Agile Data Science 2.0 (O'Reilly 2017) defines a methodology and a software stack with which to apply the methods. *The methodology* seeks to deliver data products in short sprints by going meta and putting the focus on the applied research process itself. *The stack* is but an example of one meeting the requirements that it be utterly scalable and utterly efficient in use by application developers as well as data engineers. It includes everything needed to build a full-blown predictive system: Apache Spark, Apache Kafka, Apache Incubating Airflow, MongoDB, ElasticSearch, Apache Parquet, Python/Flask, JQuery. This talk will cover the full lifecycle of large data application development and will show how to use lessons from agile software engineering to apply data science using this full-stack to build better analytics applications. The entire lifecycle of big data application development is discussed. The system starts with plumbing, moving on to data tables, charts and search, through interactive reports, and building towards predictions in both batch and realtime (and defining the role for both), the deployment of predictive systems and how to iteratively improve predictions that prove valuable.