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contains axons that arise in the
 oculomotor nucleus (which innervates all of
  the oculomotor muscles except the superior
  oblique and lateral rectus)
 Edinger–Westphal nucleus (which sends
  preganglionic parasympathetic axons to the
  ciliary ganglion).
 leaves the brain on the medial side of the
  cerebral peduncle, behind the posterior
  cerebral artery and in front of the superior
  cerebellar artery.
 then passes anteriorly, parallel to the
  internal carotid artery in the lateral wall of
  the cavernous sinus, leaving the cranial
  cavity by way of the superior orbital fissure.
 Thesomatic efferent portion of the nerve
 innervates the levator palpebrae superioris
 muscle; the superior, medial, and inferior
 rectus muscles; and the inferior oblique
 muscle
 Thevisceral efferent portion innervates two
 smooth intraocular muscles: the ciliary and
 the constrictor pupillae.
 Strabismus   (squint) is the deviation of one
  or both eyes.
 In internal strabismus, the visual axes cross
  each other
 in external strabismus, the visual axes
  diverge from each other
 Diplopia (double vision) is a subjective
  phenomenon reported to be present when
  the patient is, usually, looking with both eyes
 caused by misalignment of the visual axes
 Ptosis (lid drop) is caused by weakness or
  paralysis of the levator palpebrae superioris
  muscle
 seen with lesions of nerve III and sometimes
  in patients with myasthenia gravis.
 External  ophthalmoplegia is characterized
  by divergent strabismus, diplopia, and ptosis.
 The eye deviates downward and outward.
 This corresponds to the weaknesses of the
  medial, superior, and inferior recti and the
  inferior oblique muscles.
 position of the eye is described by the
  mnemonic "down and out."
 Internal ophthalmoplegia is characterized
  by a dilated pupil and loss of light and
  accommodation reflexes.
 There may be paralysis of individual muscles
  of nerve III
 Isolatedinvolvement of nerve III (often with
 a dilated pupil) occurs as an early sign in
 uncal herniation because of expanding
 hemispheric mass lesions that compress the
 nerve against the tentorium
 Nerve  III crosses the internal carotid, where
  it joins the posterior communicating artery;
  aneurysms of the posterior communicating
  artery thus can compress the nerve
 Isolated nerve III palsy also occurs in
  diabetes, presumably because of ischemic
  damage, and when caused by diabetes, often
  spares the pupil
 the  only crossed cranial nerve
 originates from the trochlear nucleus, which
  is a group of specialized motor neurons
  located just caudal to the CN III nucleus
  within the lower midbrain.
 Axons  cross within the midbrain, and then
  emerge contralaterally on the dorsal surface
  of the brain stem.
 nerve then curves ventrally between the
  posterior cerebral and superior cerebellar
  arteries (lateral to CN III).
 continues anteriorly in the lateral wall of the
  cavernous sinus and enters the orbit via the
  superior orbital fissure.
 innervates the superior oblique muscle
 rare condition
 slight convergent strabismus and diplopia on
  looking downward
 patient cannot look downward and inward -
  has difficulty in descending stairs.
 head is tilted as a compensatory adjustment;
  this may be the first indication of a trochlear
  lesion.
 arises from neurons of the abducens nucleus
  located within the dorsomedial tegmentum
  within the caudal pons.
 emerges from the pontomedullary fissure,
  passes through the cavernous sinus close to
  the internal carotid, and exits from the
  cranial cavity via the superior orbital fissure
 long intracranial course makes it vulnerable
  to pathologic processes in the posterior and
  middle cranial fossae.
 innervates the lateral rectus muscle
 few  proprioceptive fibers from the muscles
  of the eye are present in nerves III, IV, and VI
  and in some other nerves that innervate
  striated muscles.
 central termination of these fibers is in the
  mesencephalic nucleus of V
 most common owing to the long course of
  nerve VI.
 weakness of eye abduction
 convergent strabismus and diplopia.
 affected eye deviates medially, i.e., in the

  direction of the opposing muscle
Cranial nerves iii, iv,vi
Cranial nerves iii, iv,vi

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Cranial nerves iii, iv,vi

  • 1.
  • 2.
  • 3.
  • 4.
  • 5. contains axons that arise in the  oculomotor nucleus (which innervates all of the oculomotor muscles except the superior oblique and lateral rectus)  Edinger–Westphal nucleus (which sends preganglionic parasympathetic axons to the ciliary ganglion).
  • 6.  leaves the brain on the medial side of the cerebral peduncle, behind the posterior cerebral artery and in front of the superior cerebellar artery.  then passes anteriorly, parallel to the internal carotid artery in the lateral wall of the cavernous sinus, leaving the cranial cavity by way of the superior orbital fissure.
  • 7.  Thesomatic efferent portion of the nerve innervates the levator palpebrae superioris muscle; the superior, medial, and inferior rectus muscles; and the inferior oblique muscle
  • 8.  Thevisceral efferent portion innervates two smooth intraocular muscles: the ciliary and the constrictor pupillae.
  • 9.  Strabismus (squint) is the deviation of one or both eyes.  In internal strabismus, the visual axes cross each other  in external strabismus, the visual axes diverge from each other
  • 10.  Diplopia (double vision) is a subjective phenomenon reported to be present when the patient is, usually, looking with both eyes  caused by misalignment of the visual axes
  • 11.  Ptosis (lid drop) is caused by weakness or paralysis of the levator palpebrae superioris muscle  seen with lesions of nerve III and sometimes in patients with myasthenia gravis.
  • 12.  External ophthalmoplegia is characterized by divergent strabismus, diplopia, and ptosis.  The eye deviates downward and outward.  This corresponds to the weaknesses of the medial, superior, and inferior recti and the inferior oblique muscles.  position of the eye is described by the mnemonic "down and out."
  • 13.  Internal ophthalmoplegia is characterized by a dilated pupil and loss of light and accommodation reflexes.  There may be paralysis of individual muscles of nerve III
  • 14.
  • 15.  Isolatedinvolvement of nerve III (often with a dilated pupil) occurs as an early sign in uncal herniation because of expanding hemispheric mass lesions that compress the nerve against the tentorium
  • 16.  Nerve III crosses the internal carotid, where it joins the posterior communicating artery; aneurysms of the posterior communicating artery thus can compress the nerve  Isolated nerve III palsy also occurs in diabetes, presumably because of ischemic damage, and when caused by diabetes, often spares the pupil
  • 17.  the only crossed cranial nerve  originates from the trochlear nucleus, which is a group of specialized motor neurons located just caudal to the CN III nucleus within the lower midbrain.
  • 18.  Axons cross within the midbrain, and then emerge contralaterally on the dorsal surface of the brain stem.  nerve then curves ventrally between the posterior cerebral and superior cerebellar arteries (lateral to CN III).
  • 19.  continues anteriorly in the lateral wall of the cavernous sinus and enters the orbit via the superior orbital fissure.  innervates the superior oblique muscle
  • 20.  rare condition  slight convergent strabismus and diplopia on looking downward  patient cannot look downward and inward - has difficulty in descending stairs.  head is tilted as a compensatory adjustment; this may be the first indication of a trochlear lesion.
  • 21.  arises from neurons of the abducens nucleus located within the dorsomedial tegmentum within the caudal pons.  emerges from the pontomedullary fissure, passes through the cavernous sinus close to the internal carotid, and exits from the cranial cavity via the superior orbital fissure
  • 22.
  • 23.  long intracranial course makes it vulnerable to pathologic processes in the posterior and middle cranial fossae.  innervates the lateral rectus muscle
  • 24.  few proprioceptive fibers from the muscles of the eye are present in nerves III, IV, and VI and in some other nerves that innervate striated muscles.  central termination of these fibers is in the mesencephalic nucleus of V
  • 25.  most common owing to the long course of nerve VI.  weakness of eye abduction  convergent strabismus and diplopia.  affected eye deviates medially, i.e., in the direction of the opposing muscle