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Albinism is a congenital disorder characterized by
 complete or partial absence of pigments in hair ,
                  skin and eyes.

Albinism is caused by a genetic lack of melanin

Melanin is synthesized from the amino acid
tyrosine

Tyrosinase breaks down tyrosine

People with albinism have been passed down a
nonfunctional tyrosinase allele, which does not
allow them to produce melanin
TYPES OF ALBINISM

In humans there are two main types of albinism:
OCULOCUTANEOUS affecting the eyes, skin and hair
OCULAR affecting the eyes only.
SIGNS AND SYMPTOMS
Number of visual defects such as photophobia ,
nystagmus and astigmatism
Lack of skin pigmentation making more susceptible to
sunburn and skin cancer
Absence of normal pigments in eyes resulting in pale
blue or red eyes
GENETICS OF ALBINISM

Most forms of albinism are the result of biological
inheritance of genetically recessive alleles passed
from both parents to an individual.
Organisms can be carriers of genes for albinism
without exhibiting any traits,albinistic offspring can be
produced by two non-albinistic parents.
If we represent dominant allele for albinism as B and
recessive allele as b than we can justify by the help of
this test cross that two normal parents can have an
albino child:
         XBXb (Mother)                XBY(Father)




  1               2              3                4
 XBXB           XBXb             XBY             XbY
            Normal male                Affected male
Key:
            Normal female              Carrier female
Albinism in animals
Albinism has been observed in many animals also.
TREATMENT OF ALBINISM


There are few possible
treatments such as,
Ultra violet protective clothing,
sunglasses and sunscreen SPF 15
or higher
INCIDENCE OF ALBINISM

The international average for albinism is about 1
in 20,000.

There are some incidences where albinism is
more than 10 times more prevalent, these take
place in south western native American tribes.

This is said to be so prevalent due to one single
carrier.

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Albinism

  • 1.
  • 2. Albinism is a congenital disorder characterized by complete or partial absence of pigments in hair , skin and eyes. Albinism is caused by a genetic lack of melanin Melanin is synthesized from the amino acid tyrosine Tyrosinase breaks down tyrosine People with albinism have been passed down a nonfunctional tyrosinase allele, which does not allow them to produce melanin
  • 3. TYPES OF ALBINISM In humans there are two main types of albinism: OCULOCUTANEOUS affecting the eyes, skin and hair OCULAR affecting the eyes only.
  • 4. SIGNS AND SYMPTOMS Number of visual defects such as photophobia , nystagmus and astigmatism Lack of skin pigmentation making more susceptible to sunburn and skin cancer Absence of normal pigments in eyes resulting in pale blue or red eyes
  • 5. GENETICS OF ALBINISM Most forms of albinism are the result of biological inheritance of genetically recessive alleles passed from both parents to an individual. Organisms can be carriers of genes for albinism without exhibiting any traits,albinistic offspring can be produced by two non-albinistic parents.
  • 6. If we represent dominant allele for albinism as B and recessive allele as b than we can justify by the help of this test cross that two normal parents can have an albino child: XBXb (Mother) XBY(Father) 1 2 3 4 XBXB XBXb XBY XbY Normal male Affected male Key: Normal female Carrier female
  • 7. Albinism in animals Albinism has been observed in many animals also.
  • 8. TREATMENT OF ALBINISM There are few possible treatments such as, Ultra violet protective clothing, sunglasses and sunscreen SPF 15 or higher
  • 9. INCIDENCE OF ALBINISM The international average for albinism is about 1 in 20,000. There are some incidences where albinism is more than 10 times more prevalent, these take place in south western native American tribes. This is said to be so prevalent due to one single carrier.