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Acupuncture


UBC Students for Science Based Medicine




                UBC SBM
UBC SBM


                    What I’ll Cover
• Acupuncture
   – History, Definition, and Basis in Traditional Chinese Medicine


• What does the research say about acupuncture for …
   – Nausea?

   – Pain?



   – Infertility?



   – Asthma?
UBC SBM


History: Unclear
UBC SBM


                           History

                                                  1800 CE
                                                  • Connection
1000 CE                                             between electricity
                                                    and nerves made
• Professionalized




                     1600 CE
                     • Circulatory system fully
                       described
                     • Reproduction not
                       understood.
What is acupuncture?
BC Health Professions Act:
Traditional Chinese Medicine Practitioners
and Acupuncturists Regulation

Acupuncture
    is an act of stimulation, by means of
    needles, of specific sites on the skin, to
    promote, maintain, restore or improve
    health, to prevent a disorder, disease or to
    alleviate pain and includes
         A. Needles: mechanical, thermal,
             electrical
         B. Lasers & magnets
         C. Burning dried leaves (moxibustion)




                                  UBC SBM
UBC SBM


             What is Acupuncture?
College of TCM Practitioners and Acupuncturists
of BC
• Acupuncture is a procedure in Traditional Chinese
   Medicine.

•   TCM grows out of Daoism (religion/philosophy):
     – Yin/Yang (bright/dark)
     – Five Elements
UBC SBM


What is Acupuncture?
UBC SBM


                           Acupuncture Basics
     •   Scientists in China divided on whether meridian
         system is relevant




     •   Current research does not strongly support the idea
         that there is something unique about acupuncture
         points or that meridians exist




1)   Sampson, WI (September/October 1996). "Traditional Medicine and Pseudoscience in China: A Report of the Second
     CSICOP Delegation (Part 2)". Skeptical Inquirer 20 (5).

1)   Langevin, H. M., & Yandow, J. A. (2002). Relationship of acupuncture points and meridians to connective tissue planes. THE
     ANATOMICAL RECORD (NEW ANAT.), 269, 257-265. Retrieved from http://www.uvm.edu/annb/faculty/PDFs/257.pdf
UBC SBM


                  Research
• There’s a lot of research out
  there
Levels of Research




      UBC SBM
UBC SBM


Why reviews have different results
• Reasons why reviews come up with different
  conclusions:

   – No one likes publishing negative studies, so positive studies are
     overrepresented

   – Different statistical formulas

   – Different studies
UBC SBM


                                          Nausea


                                                2008                        2009
                                             (10 studies)                (40 studies)


                  Acupuncture




Abraham, J. (2008). "Acupressure and acupuncture in preventing and managing postoperative nausea and
vomiting in adults". Journal of perioperative practice 18 (12): 543–551.

Lee A, Fan, LTY (2009). Lee, Anna. ed. "Stimulation of the wrist acupuncture point P6 for preventing postoperative
nausea and vomiting". Cochrane Database of Systematic Reviews (Online) (2): CD003281.
UBC SBM


        Nausea: Conclusion
• Acupuncture at wrist helps with nausea
  after surgery

• But
  – No difference between needles and pressure
  – Not better than present medication
  – Only tested nausea after surgery
    • Not food poisoning or motion sickness
UBC SBM


       Pain


Somewhat unclear


Conflicting Evidence
UBC SBM


                                                    Pain
                                                 Review of
                                                  reviews



Review 1                 Review 2                  Review 3                 Review 4                Review 5




                         Individual Studies
Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review
of reviews." Pain 152 (4): 755–764.
UBC SBM


              Pain: Review of reviews
                             •    Migraines
                             •    Tension Headaches
                             •    Rheumatoid Arthritis
                             •    Cancer Pain
                             •    Fibromyalgia (long term body wide pain)
                             •    Muscular-skeletal Pain
                             •    Shoulder Pain
                             •    During Surgery Pain

                             • After Surgery Pain
                             • Jaw Joint Pain
                             • Sciatica (leg pain)

                             • Neck Pain
                             • Low Back Pain
                             • Osteoarthritis

Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review
of reviews." Pain 152 (4): 755–764.
UBC SBM


    Pain: Chronic Low-Back Pain
                                 People who experienced
                                     pain reduction
                        40
                        30
                        20
                        10
                         0
                               Acupuncture           Fake        No
                                                  Acupuncture Treatment
• But
     – Short term only (3 months)
     – Not better than conventional therapies



Furlan, Andrea D; Van Tulder, Maurits W; Cherkin, Dan; Tsukayama, Hiroshi; Lao, Lixing; Koes, Bart W; Berman,
Brian M (2005). Furlan, Andrea D. ed. "Acupuncture and dry-needling for low back pain" (PDF). Cochrane
Database Syst Rev (1): CD001351.
UBC SBM


              Pain: Review of reviews
                             •    Migraines
                             •    Tension Headaches
                             •    Rheumatoid Arthritis
                             •    Cancer Pain
                             •    Fibromyalgia (long term body wide pain)
                             •    Muscular-skeletal Pain
                             •    Shoulder Pain
                             •    During Surgery Pain

                             • After Surgery Pain
                             • Jaw Joint Pain
                             • Sciatica (leg pain)

                             • Neck Pain
                             • Low Back Pain
                             • Osteoarthritis

Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review
of reviews." Pain 152 (4): 755–764.
UBC SBM


          Pain: Conclusion
1. Small pain reduction in some types of
   pain, no reduction in most other types

1. Little or no difference between
   acupuncture and fake acupuncture
UBC SBM


Infertility
UBC SBM


                         Infertility


              Review 1     Review 2   Review 3   Review 4
              (2008)       (2008)     (2009)     (2011)


More
Pregnancies


More
Babies
UBC SBM


           Infertility: Conclusion
• Conclusion:
   – There is conflicting evidence about whether acupuncture treats
     infertility

   – Most reviews suggest acupuncture does not increase odds of
     giving birth
UBC SBM


                                        Asthma
• Long term lung disease.

• Reversible breathing difficulty.

• Often, but not always, caused
  by allergies.

• 250,000 deaths/year
  worldwide (GINA, 2009)


"Global Strategy for Asthma Management and Prevention 2010
(update)" (PDF). Global Initiative for Asthma. 2010.
UBC SBM


                                            Asthma
• Review 1 (2002):
     – “The current analysis did not find evidence of the efficacy of acupuncture in the
       treatment of patients with asthma”




• Review 2 (2002):
     – “There is not enough evidence to make recommendations about the value of
       acupuncture in asthma treatment.”




 Linde K, Jobst K, Panton J. Acupuncture for chronicasthma (Cochrane Review). The Cochrane Library, Issue 2. Oxford,
 Update Software, 2002.

 Martin J, Donaldson AN, Villarroel R, Parmar MKB, Ernst E, Higginson IJ. Efficacy of acupuncture in asthma: systematic
 review and meta-analysis of published data from 11 randomised controlled trials. The European Respiratory Journal.
 2002;20(4):846–852.
Placebo Effect:
                       Does it really help?
            Feeling Better                                                    Getting Better




Wechsler ME, Kelley JM, Boyd IO, Dutile S, Marigowda G, et al. (2011) Active albuterol or placebo, sham acupuncture, or no
intervention in asthma. N Engl J Med 365: 119–126.
Acupuncture Conclusion:                                             UBC SBM


               Benefits
            Subjective                                  Objective
After Surgery Nausea                      Infertility
   –    Acupuncture at wrist seems to         –    Latest review says fertility does
        help                                       not increase chance of having a
   –    No difference between needles              baby
        and pressure
                                          Asthma
Pain Weak
  -                                          - – Best evidence does not
                                                   Evidence is weak
  - – Comparable to conventional
         Both fake acupuncture and real        – support it’s use
                                                   Existing therapies prevent death
      therapies
         acupuncture have small effect       - Conventional therapies
  - – Those therapies aren’ttypes of
         Mostly equal for most great             much better (Asthma)
      to begin with
         pain                                - No competing therapy (IVF)
   –    For some types of pain real               - Except IVF is a therapy
        acupuncture seems to be better               itself that does help
        than fake acupuncture but                    with infertility
        there’s conflicting evidence
UBC SBM
              Acupuncture Conclusion:
               Risks and side effects
   – Bacterial and viral infections
          • Non sterile needling
          • Small risk, but still real


   – Trauma
          •   Not bleeding (surprisingly)
          •   Pain, headache, numbness
          •   Pneumothorax
          •   Death




Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review of
reviews" (pdf). Pain 152 (4): 755–764.
Concluding Statements
• Acupuncture:
  –   minor benefits, evidence generally weak
  –   minor to major risks
  –   has been studied for decades and still no clear effect
  –   If acupuncture were a drug it would not make it to
      market and would be abandoned


• Alternative Medicine
• Controversial to recommend
                           UBC SBM
Works Cited
1. Manheimer, E., Zhang, G., Udoff, L., et al., 2008. Effects ofacupuncture on rates of pregnancy and
   live birth among womenundergoing in vitro fertilization: systematic review andmeta-analysis. British
   Medical Journal 336, 545–549.
2. El-Toukhy, T., Sunkara, S.K., Khairy, M., et al., 2008. A systematicreview and meta-analysis of
   acupuncture in in vitro fertilization.British Journal of Obstetrics and Gynaecology 10, 1203–1213.
3. Sunkara, S.K., Coomarasamy, A., Khalaf, Y., El-Toukhy, T., 2009.Acupuncture and in vitro
   fertilization: updated meta-analysis.Human Reproduction 24, 2047–2048.
4. Moy I, Milad MP, Barnes R, Confino E, Kazer RR, Zhang X. Randomized controlled trial: effects of
   acupuncture on pregnancy rates in women undergoing in vitro fertilization. Fertil Steril.
   2011;95:583–7. doi: 10.1016/j.fertnstert.2010.05.024
Acupuncture
            By Ratib Islam
UBC Students for Science Based Medicine




                UBC SBM

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Acupuncture

  • 1. Acupuncture UBC Students for Science Based Medicine UBC SBM
  • 2. UBC SBM What I’ll Cover • Acupuncture – History, Definition, and Basis in Traditional Chinese Medicine • What does the research say about acupuncture for … – Nausea? – Pain? – Infertility? – Asthma?
  • 4. UBC SBM History 1800 CE • Connection 1000 CE between electricity and nerves made • Professionalized 1600 CE • Circulatory system fully described • Reproduction not understood.
  • 5. What is acupuncture? BC Health Professions Act: Traditional Chinese Medicine Practitioners and Acupuncturists Regulation Acupuncture is an act of stimulation, by means of needles, of specific sites on the skin, to promote, maintain, restore or improve health, to prevent a disorder, disease or to alleviate pain and includes A. Needles: mechanical, thermal, electrical B. Lasers & magnets C. Burning dried leaves (moxibustion) UBC SBM
  • 6. UBC SBM What is Acupuncture? College of TCM Practitioners and Acupuncturists of BC • Acupuncture is a procedure in Traditional Chinese Medicine. • TCM grows out of Daoism (religion/philosophy): – Yin/Yang (bright/dark) – Five Elements
  • 7. UBC SBM What is Acupuncture?
  • 8. UBC SBM Acupuncture Basics • Scientists in China divided on whether meridian system is relevant • Current research does not strongly support the idea that there is something unique about acupuncture points or that meridians exist 1) Sampson, WI (September/October 1996). "Traditional Medicine and Pseudoscience in China: A Report of the Second CSICOP Delegation (Part 2)". Skeptical Inquirer 20 (5). 1) Langevin, H. M., & Yandow, J. A. (2002). Relationship of acupuncture points and meridians to connective tissue planes. THE ANATOMICAL RECORD (NEW ANAT.), 269, 257-265. Retrieved from http://www.uvm.edu/annb/faculty/PDFs/257.pdf
  • 9. UBC SBM Research • There’s a lot of research out there
  • 11. UBC SBM Why reviews have different results • Reasons why reviews come up with different conclusions: – No one likes publishing negative studies, so positive studies are overrepresented – Different statistical formulas – Different studies
  • 12. UBC SBM Nausea 2008 2009 (10 studies) (40 studies) Acupuncture Abraham, J. (2008). "Acupressure and acupuncture in preventing and managing postoperative nausea and vomiting in adults". Journal of perioperative practice 18 (12): 543–551. Lee A, Fan, LTY (2009). Lee, Anna. ed. "Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting". Cochrane Database of Systematic Reviews (Online) (2): CD003281.
  • 13. UBC SBM Nausea: Conclusion • Acupuncture at wrist helps with nausea after surgery • But – No difference between needles and pressure – Not better than present medication – Only tested nausea after surgery • Not food poisoning or motion sickness
  • 14. UBC SBM Pain Somewhat unclear Conflicting Evidence
  • 15. UBC SBM Pain Review of reviews Review 1 Review 2 Review 3 Review 4 Review 5 Individual Studies Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review of reviews." Pain 152 (4): 755–764.
  • 16. UBC SBM Pain: Review of reviews • Migraines • Tension Headaches • Rheumatoid Arthritis • Cancer Pain • Fibromyalgia (long term body wide pain) • Muscular-skeletal Pain • Shoulder Pain • During Surgery Pain • After Surgery Pain • Jaw Joint Pain • Sciatica (leg pain) • Neck Pain • Low Back Pain • Osteoarthritis Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review of reviews." Pain 152 (4): 755–764.
  • 17. UBC SBM Pain: Chronic Low-Back Pain People who experienced pain reduction 40 30 20 10 0 Acupuncture Fake No Acupuncture Treatment • But – Short term only (3 months) – Not better than conventional therapies Furlan, Andrea D; Van Tulder, Maurits W; Cherkin, Dan; Tsukayama, Hiroshi; Lao, Lixing; Koes, Bart W; Berman, Brian M (2005). Furlan, Andrea D. ed. "Acupuncture and dry-needling for low back pain" (PDF). Cochrane Database Syst Rev (1): CD001351.
  • 18. UBC SBM Pain: Review of reviews • Migraines • Tension Headaches • Rheumatoid Arthritis • Cancer Pain • Fibromyalgia (long term body wide pain) • Muscular-skeletal Pain • Shoulder Pain • During Surgery Pain • After Surgery Pain • Jaw Joint Pain • Sciatica (leg pain) • Neck Pain • Low Back Pain • Osteoarthritis Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review of reviews." Pain 152 (4): 755–764.
  • 19. UBC SBM Pain: Conclusion 1. Small pain reduction in some types of pain, no reduction in most other types 1. Little or no difference between acupuncture and fake acupuncture
  • 21. UBC SBM Infertility Review 1 Review 2 Review 3 Review 4 (2008) (2008) (2009) (2011) More Pregnancies More Babies
  • 22. UBC SBM Infertility: Conclusion • Conclusion: – There is conflicting evidence about whether acupuncture treats infertility – Most reviews suggest acupuncture does not increase odds of giving birth
  • 23. UBC SBM Asthma • Long term lung disease. • Reversible breathing difficulty. • Often, but not always, caused by allergies. • 250,000 deaths/year worldwide (GINA, 2009) "Global Strategy for Asthma Management and Prevention 2010 (update)" (PDF). Global Initiative for Asthma. 2010.
  • 24. UBC SBM Asthma • Review 1 (2002): – “The current analysis did not find evidence of the efficacy of acupuncture in the treatment of patients with asthma” • Review 2 (2002): – “There is not enough evidence to make recommendations about the value of acupuncture in asthma treatment.” Linde K, Jobst K, Panton J. Acupuncture for chronicasthma (Cochrane Review). The Cochrane Library, Issue 2. Oxford, Update Software, 2002. Martin J, Donaldson AN, Villarroel R, Parmar MKB, Ernst E, Higginson IJ. Efficacy of acupuncture in asthma: systematic review and meta-analysis of published data from 11 randomised controlled trials. The European Respiratory Journal. 2002;20(4):846–852.
  • 25. Placebo Effect: Does it really help? Feeling Better Getting Better Wechsler ME, Kelley JM, Boyd IO, Dutile S, Marigowda G, et al. (2011) Active albuterol or placebo, sham acupuncture, or no intervention in asthma. N Engl J Med 365: 119–126.
  • 26. Acupuncture Conclusion: UBC SBM Benefits Subjective Objective After Surgery Nausea Infertility – Acupuncture at wrist seems to – Latest review says fertility does help not increase chance of having a – No difference between needles baby and pressure Asthma Pain Weak - - – Best evidence does not Evidence is weak - – Comparable to conventional Both fake acupuncture and real – support it’s use Existing therapies prevent death therapies acupuncture have small effect - Conventional therapies - – Those therapies aren’ttypes of Mostly equal for most great much better (Asthma) to begin with pain - No competing therapy (IVF) – For some types of pain real - Except IVF is a therapy acupuncture seems to be better itself that does help than fake acupuncture but with infertility there’s conflicting evidence
  • 27. UBC SBM Acupuncture Conclusion: Risks and side effects – Bacterial and viral infections • Non sterile needling • Small risk, but still real – Trauma • Not bleeding (surprisingly) • Pain, headache, numbness • Pneumothorax • Death Ernst, E.; Lee, M. S.; Choi, T. Y. (2011). "Acupuncture: Does it alleviate pain and are there serious risks? A review of reviews" (pdf). Pain 152 (4): 755–764.
  • 28. Concluding Statements • Acupuncture: – minor benefits, evidence generally weak – minor to major risks – has been studied for decades and still no clear effect – If acupuncture were a drug it would not make it to market and would be abandoned • Alternative Medicine • Controversial to recommend UBC SBM
  • 29. Works Cited 1. Manheimer, E., Zhang, G., Udoff, L., et al., 2008. Effects ofacupuncture on rates of pregnancy and live birth among womenundergoing in vitro fertilization: systematic review andmeta-analysis. British Medical Journal 336, 545–549. 2. El-Toukhy, T., Sunkara, S.K., Khairy, M., et al., 2008. A systematicreview and meta-analysis of acupuncture in in vitro fertilization.British Journal of Obstetrics and Gynaecology 10, 1203–1213. 3. Sunkara, S.K., Coomarasamy, A., Khalaf, Y., El-Toukhy, T., 2009.Acupuncture and in vitro fertilization: updated meta-analysis.Human Reproduction 24, 2047–2048. 4. Moy I, Milad MP, Barnes R, Confino E, Kazer RR, Zhang X. Randomized controlled trial: effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization. Fertil Steril. 2011;95:583–7. doi: 10.1016/j.fertnstert.2010.05.024
  • 30. Acupuncture By Ratib Islam UBC Students for Science Based Medicine UBC SBM

Editor's Notes

  1. Science hasn’t found any anything that corrseponds to QI/meridiansSome scientists think Qi is a real and useful way to understand the human body. Others think that it’s just old medicine and no longer relevant.In China, some scientists think Qi is a useful abstraction in modeling bodily processes, while others dismiss it as philosophy with no relationship to modern physiology/medicine (1)TRANSITION. NOW YOU’VE COVERED THE BASICS, LET’S LOOK AT APPLICATION.
  2. Reviews of reviews are better than individual studiesUsing systematic reviews, we can get a broader picture of the evidence.Make an animation for the top of pyramids.
  3. Emphasize the More Babies
  4. Layify more.
  5. `This is the only thing I’m talking about in which people die.IT’S INCREDIBLY IMPORTANT THAT WHATEVER TREATMENT CLAIMS TO TREAT ASTHMA HAS SOLID EVIDENCE BEHIND IT BECAUSE YOU CAN DIE
  6. GET RID OF EVERYTHING EXCEPT THE MAIN CONCLUSION QUOTE FROM COCHRANE (BUT DON’T’ SAY OR WRITE COCHRANE)
  7. EXPLAIN IN DETAILALBUTEROL = PUFFERWHITE OUT ALL DETAILS EXCEPT NAMES. CHANGE AXES TO FEEL BETTER AND GET BETTER