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Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
1
Authors
Cristina Farrell, MD, Children’s Hospital Boston, Harvard Medical School
Leonard Rappaport, MD, MS, Children’s Hospital Boston, Harvard Medical School
Neelam Sell, MD, The Children’s Hospital of Philadelphia
Brian Tang, MD, Lucile Packard Children’s Hospital, Stanford University School of Medicine
Editors
Georgina Peacock, MD, MPH, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention
Carol Weitzman, MD, Yale University School of Medicine
Jana Thomas, MPA, Porter Novelli
Treatments for
Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
2
Learning Objectives
1. Evaluate the etiology of changes to behavior and
functioning in children with autism spectrum disorder
(ASD) and describe strategies to analyze these changes.
– Identify specific causes that can increase maladaptive behavior.
– Describe the components of a functional behavioral analysis.
– Be familiar with rating scales that can be used to assess behavior
change in children with ASD.
2. Develop knowledge regarding specific options to treat
maladaptive behaviors in children with ASD.
– Understand the evidence-based indications for the initiation of
pharmacotherapy in children with ASD.
– Become familiar with the classes of drugs used to treat children with
ASD.
– Describe the most common complementary and alternative medicine
(CAM) therapies used to treat children with ASD.
– Learn strategies to engage families around the use of CAM.

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
3
Part I
• Kofi is an overweight 8-year-old boy who was
diagnosed with ASD and borderline intellectual
functioning …

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
4
What stands out to you about this case?

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
5
What would you do next?

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
6
Part II
• Kofi’s mother returns for a follow-up visit. She is
awaiting her consultation with the
developmental-behavioral pediatrician…

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
7
What stands out to you about this
discussion?

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
8
Part III - Epilogue
• Kofi’s mother calls you with an update after
seeing the developmental-behavioral
pediatrician…

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
9
How would you apply the information in
this case?
What did you learn through this case?

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
10
Post-Learning Exercise
Treatments for Autism
Talk with a family who has a child or adolescent with
ASD. Discuss the challenges in managing symptoms,
such as aggression, obsessions, and other issues.

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
11
Potential Next Case:
Autism Spectrum Disorder-Specific
Anticipatory Guidance
Case Goals
• Recognize some of the common
developmental issues that present in children
with ASD and how to evaluate them.
• Identify management approaches and
strategies for the common developmental
issues seen in children with ASD.

Treatments for Autism Spectrum Disorder
Autism Case Training:
A Developmental-Behavioral Pediatrics Curriculum
12
Developed in partnership with
Health Resources and Services Administration
Maternal and Child Health Bureau

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Photo Credit: Getty Images/iStockphoto Week 4: Therapy for Patients With Major Depressive Disorder (MDD) Mood disorders can impact every facet of a human being’s life, making the most basic activities difficult for patients and their families. This was the case for 13-year-old Jeanette, who was struggling at home and at school. For more than 8 years, Jeanette suffered from temper tantrums, impulsiveness, inappropriate behavior, difficulty in judgment, and sleep issues. As a PNP working with pediatric patients, you must be able to assess whether these symptoms are caused by psychological, social, or underlying growth and development issues. You must then be able recommend appropriate therapies. This week, as you examine antidepressant therapies, you explore the assessment and treatment of three populations: pediatrics, adults, and geriatrics. The focus of your assessment tool, a decision tree, will specifically center on one of the most vulnerable populations, pediatrics. Please remember, you must also consider the ethical and legal implications of these therapies. You will also complete a Quiz on the concepts addressed throughout this module. Learning Objectives Students will: • Assess patient factors and history to develop personalized plans of antidepressant therapy across the lifespan • Analyze factors that influence pharmacokinetic and pharmacodynamic processes in pediatric, adult, and geriatric patients requiring antidepressant therapy • Synthesize knowledge of providing care to pediatric, adult, and geriatric patients presenting for antidepressant therapy • Analyze ethical and legal implications related to prescribing antidepressant therapy to patients across the lifespan Assignment: Assessing and Treating Pediatric Patients With Mood Disorders When pediatric patients present with mood disorders, the process of assessing, diagnosing, and treating them can be quite complex. Children not only present with different signs and symptoms than adult patients with the same disorders, they also metabolize medications much differently. Yet, there may be times when the same psychopharmacologic treatments may be used in both pediatric and adult cases with major depressive disorders. As a result, psychiatric nurse practitioners must exercise caution when prescribing psychotropic medications to these patients. For this Assignment, as you examine the patient case study in this week’s Learning Resources, consider how you might assess and treat pediatric patients presenting with mood disorders. To prepare for this Assignment: • Review this week’s Learning Resources, including the Medication Resources indicated for this week. • Reflect on the psychopharmacologic treatments you might recommend for the assessment and treatment of pediatric patients requiring antidepressant therapy. The Assignment: 5 pages Examine Case Study: An African American Child Suffering From Depression. You will be asked ...

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