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Last minute mrcp1 revision

Sherif Elbadrawy

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22 de jun de 2014

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BADRAWY MRCP Revision

‫اﻟرﺣﯾم‬ ‫اﻟرﺣﻣن‬ ‫ﷲ‬ ‫ﺑﺳم‬
This is a collection of commonly
tested facts for part 1
MRCP ...including the 100
commonly te...

a must read before part 1 ...
U'll find at least 20-30
Questions in your MRCP 1
exam from these notes.
‫ﷲ‬ ‫ﺷﺎء‬ ‫إن‬ 1b
B...

Somatisation vs
hypochondria
2a
BADRAWY MRCP Revision

Somatisation = patient
concerned about Symptoms.
HypochonDria = patient
concerned about underlying
Disease eg Cancer.
2b
B...

DiGeorge syndrome =
affects what type of cell?
3a
BADRAWY MRCP Revision

- a T-cell disorder
3b
BADRAWY MRCP Revision

Antithrombotic therapy in
bioprosthetic vs
mechanical heart valves
4a
BADRAWY MRCP Revision

- bioprosthetic: aspirin -
mechanical: warfarin +
aspirin
4b
BADRAWY MRCP Revision

Goodpasture's syndrome -
histology?
5a
BADRAWY MRCP Revision

- IgG deposits on renal
biopsy - anti-GBM
antibodies
5b
BADRAWY MRCP Revision

Adrenaline induced
ischaemia treatment
6a
BADRAWY MRCP Revision

- phentolamine
6b
BADRAWY MRCP Revision

Complete heart block
following a MI?
7a
BADRAWY MRCP Revision

- right coronary artery
lesion
7b
BADRAWY MRCP Revision

Wilson's disease: diagnosis
8a
BADRAWY MRCP Revision

- serum caeruloplasmin is
decreased
8b
BADRAWY MRCP Revision

Fluctuating
confusion/consciousness in
elderly plus/minus
deterioration ?
9a
BADRAWY MRCP Revision

chronic subdural. Can last
even longer than 6 months
9b
BADRAWY MRCP Revision

Acute promyelocytic
leukaemia translocation
10a
BADRAWY MRCP Revision

- t(15;17)
10b
BADRAWY MRCP Revision

Dermatophyte nail
infections Rx
11a
BADRAWY MRCP Revision

- use oral terbinafine
11b
BADRAWY MRCP Revision

Actions of BNP
12a
BADRAWY MRCP Revision

- vasodilator - diuretic and
natriuretic - suppresses
both sympathetic tone and
the renin-angiotensin-
aldosterone system
...

Burning thigh pain - ?nerve
compression
13a
BADRAWY MRCP Revision

? meralgia paraesthetica -
lateral cutaneous nerve of
thigh compression
13b
BADRAWY MRCP Revision

URTI symptoms +
amoxicillin --> rash
14a
BADRAWY MRCP Revision

?glandular fever
14b
BADRAWY MRCP Revision

IgM paraproteinaemia -
15a
BADRAWY MRCP Revision

?Waldenstrom's
macroglobulinaemia
15b
BADRAWY MRCP Revision

Absolute risk reduction =
16a
BADRAWY MRCP Revision

= (Control event rate) -
(Experimental event rate)
16b
BADRAWY MRCP Revision

Terlipressin - MoA?
17a
BADRAWY MRCP Revision

= constriction of the
splanchnic vessels
17b
BADRAWY MRCP Revision

Localising bitemporal
hemianopia - upper
quadrant defect > lower
quadrant defect.
18a
BADRAWY MRCP Revision

= inferior chiasmal
compression, commonly a
pituitary tumour
18b
BADRAWY MRCP Revision

Tear-drop poikilocytes ?
19a
BADRAWY MRCP Revision

= myelofibrosis
19b
BADRAWY MRCP Revision

Localising bitemporal
hemianopia - upper
quadrant defect > lower
quadrant defect.
20a
BADRAWY MRCP Revision

= superior chiasmal
compression, commonly a
craniopharyngioma
20b
BADRAWY MRCP Revision

Imatinib - MoA
21a
BADRAWY MRCP Revision

= tyrosine kinase inhibitor
used in CML
21b
BADRAWY MRCP Revision

Flushing, diarrhoea,
bronchospasm, tricuspid
stenosis, pellagra -
diagnosis?
22a
BADRAWY MRCP Revision

--> carcinoid with liver
mets
22b
BADRAWY MRCP Revision

Flash pulmonary oedema,
U&Es worse on ACE
inhibitor, asymmetrical
kidneys: ?diagnosis
23a
BADRAWY MRCP Revision

--> renal artery stenosis -
do MR angiography
23b
BADRAWY MRCP Revision

Collapse + ARF =
24a
BADRAWY MRCP Revision

--> rhabdomyolysis - treat
with IV fluids
24b
BADRAWY MRCP Revision

Statistical power =
25a
BADRAWY MRCP Revision

1 - the probability of a type
II error
25b
BADRAWY MRCP Revision

Sarcoidosis CXR stages
26a
BADRAWY MRCP Revision

1 = BHL - 2 = BHL +
infiltrates - 3 = infiltrates -
4 = fibrosis
26b
BADRAWY MRCP Revision

Calculating breakthrough
morphine dose?
27a
BADRAWY MRCP Revision

1/6th of daily morphine
dose
27b
BADRAWY MRCP Revision

Post-natal depression
incidence?
28a
BADRAWY MRCP Revision

10% of women
28b
BADRAWY MRCP Revision

COPD - when to start
LTOT?
29a
BADRAWY MRCP Revision

2 measurements of pO2 <
7.3 kPa
29b
BADRAWY MRCP Revision

Stroke thrombolysis time
limit?
30a
BADRAWY MRCP Revision

4.5 hours
30b
BADRAWY MRCP Revision

1mg prednisolone = ?
hydrocortisone
31a
BADRAWY MRCP Revision

4mg hydrocortisone
31b
BADRAWY MRCP Revision

Finasteride MoA
32a
BADRAWY MRCP Revision

5 alpha-reductase inhibitor
- inhibits conversion of
testosterone to
dihydrotestosterone
32b
BADRAWY MRCP Revision

Finasteride treatment of
BPH may take how long
before results are seen?
33a
BADRAWY MRCP Revision

6 months
33b
BADRAWY MRCP Revision

DVLA restriction post-
seizure
34a
BADRAWY MRCP Revision

6 months
34b
BADRAWY MRCP Revision

Rx for Hypertension in
diabetics -
35a
BADRAWY MRCP Revision

ACE-inhibitors are first-
line regardless of age
35b
BADRAWY MRCP Revision

Dysphagia affecting both
solids and liquids from the
start - think?
36a
BADRAWY MRCP Revision

achalasia
36b
BADRAWY MRCP Revision

Loss of corneal reflex - key
differential?
37a
BADRAWY MRCP Revision

acoustic neuroma
37b
BADRAWY MRCP Revision

Factor V Leiden mutation
results in?
38a
BADRAWY MRCP Revision

activated protein C
resistance
38b
BADRAWY MRCP Revision

Key treatments in migraine
- acute vs prophylactic
39a
BADRAWY MRCP Revision

acute: 5-HT1 agonist -
prophylaxis: beta-blocker
39b
BADRAWY MRCP Revision

Congenital heart disease -
acyanotic - most common
cause:
40a
BADRAWY MRCP Revision

acyanotic: VSD most
common cause
40b
BADRAWY MRCP Revision

Glitazones: MoA
41a
BADRAWY MRCP Revision

agonists of PPAR-gamma
receptors
41b
BADRAWY MRCP Revision

Atrial fibrillation -
cardioversion rx:
42a
BADRAWY MRCP Revision

amiodarone + flecainide
42b
BADRAWY MRCP Revision

Adult Life Support (ALS)
adrenaline doses -
43a
BADRAWY MRCP Revision

anaphylaxis: 0.5ml 1:1,000
IM - cardiac arrest: 10ml
1:10,000 IV or 1ml of
1:1000 IV
43b
BADRAWY MRCP Revision

Bartter's syndrome ?
44a
BADRAWY MRCP Revision

AR inherited cause of
hypokalaemia associated
with normotension
44b
BADRAWY MRCP Revision

Miller Fisher syndrome -
CFs?
45a
BADRAWY MRCP Revision

areflexia, ataxia,
ophthalmoplegia
45b
BADRAWY MRCP Revision

Polycythaemia rubra vera
progression?
46a
BADRAWY MRCP Revision

around 5-15% progress to
myelofibrosis or AML
46b
BADRAWY MRCP Revision

malt workers' lung -
pathogen
47a
BADRAWY MRCP Revision

Aspergillus clavatus
47b
BADRAWY MRCP Revision

Urticaria - common drug
cause?
48a
BADRAWY MRCP Revision

Aspirin
48b
BADRAWY MRCP Revision

Antiphospholipid
syndrome in pregnancy
treatment
49a
BADRAWY MRCP Revision

aspirin + LMWH
49b
BADRAWY MRCP Revision

Causes of raised transfer
factor?
50a
BADRAWY MRCP Revision

asthma, haemorrhage, left-
to-right shunts,
polycythaemia
50b
BADRAWY MRCP Revision

Beta-blocker overdose
management:
51a
BADRAWY MRCP Revision

atropine + glucagon
51b
BADRAWY MRCP Revision

Hereditary haemorrhagic
telangiectasia - inheritance
52a
BADRAWY MRCP Revision

autosomal dominant
52b
BADRAWY MRCP Revision

Alpha-1 antitrypsin
deficiency inheritance
53a
BADRAWY MRCP Revision

autosomal recessive / co-
dominant
53b
BADRAWY MRCP Revision

Aortic stenosis
management:
54a
BADRAWY MRCP Revision

AVR if symptomatic,
otherwise cut-off is
gradient of 50 mmHg
54b
BADRAWY MRCP Revision

Live attenuated vaccines -
55a
BADRAWY MRCP Revision

BCG - MMR - oral polio -
yellow fever - oral typhoid
55b
BADRAWY MRCP Revision

Atrial fibrillation: rate
control rx -
56a
BADRAWY MRCP Revision

beta blockers (preferable to
digoxin)
56b
BADRAWY MRCP Revision

Aortic stenosis - most
common cause <65 yrs:
57a
BADRAWY MRCP Revision

bicuspid aortic valve
57b
BADRAWY MRCP Revision

Most common cardiac
defect in Turner's
syndrome?
58a
BADRAWY MRCP Revision

Bicuspid aortic valve
58b
BADRAWY MRCP Revision

Porphyria cutanea tarda -
CP?
59a
BADRAWY MRCP Revision

Bullae on hands ,blistering
photosensitive rash -
hypertrichosis -
hyperpigmentation, fragile
SKIN torn by minor trauma
59...

Amiodarone MoA
60a
BADRAWY MRCP Revision

Blocks potassium channels
60b
BADRAWY MRCP Revision

Visual changes secondary
to drugs - blue vision?
Yellow-green vision?
61a
BADRAWY MRCP Revision

blue vision: Viagra ('the
blue pill') - yellow-green
vision: digoxin
61b
BADRAWY MRCP Revision

HRT: adding a progestogen
increases the risk of?
62a
BADRAWY MRCP Revision

breast cancer
62b
BADRAWY MRCP Revision

Common cause of tumour
lysis syndrome?
63a
BADRAWY MRCP Revision

Burkitt's lymphoma
63b
BADRAWY MRCP Revision

EBV: associated
malignancies?
64a
BADRAWY MRCP Revision

Burkitt's lymphoma -
Hodgkin's lymphoma -
nasopharyngeal carcinoma
64b
BADRAWY MRCP Revision

Variables used to calculate
eGFR?
65a
BADRAWY MRCP Revision

CAGE - Creatinine, Age,
Gender, Ethnicity
65b
BADRAWY MRCP Revision

Aortic stenosis - most
common cause >65 yrs:
66a
BADRAWY MRCP Revision

calcification
66b
BADRAWY MRCP Revision

What drugs are now
preferred to thiazides in the
treatment of hypertension?
67a
BADRAWY MRCP Revision

Calcium channel blockers
67b
BADRAWY MRCP Revision

DVLA advice post CVA:
68a
BADRAWY MRCP Revision

cannot drive for 1 month
68b
BADRAWY MRCP Revision

DVLA advice following
angioplasty -
69a
BADRAWY MRCP Revision

cannot drive for 1 week
69b
BADRAWY MRCP Revision

DVLA advice post multiple
TIAs:
70a
BADRAWY MRCP Revision

cannot drive for 3 months
70b
BADRAWY MRCP Revision

DVLA advice post MI -
71a
BADRAWY MRCP Revision

cannot drive for 4 weeks
71b
BADRAWY MRCP Revision

Epilepsy medication: first-
line - partial seizure:
72a
BADRAWY MRCP Revision

carbamazepine
72b
BADRAWY MRCP Revision

Trigeminal neuralgia -
first-line Rx?
73a
BADRAWY MRCP Revision

carbamazepine
73b
BADRAWY MRCP Revision

Trastuzumab (Herceptin) -
important SE?
74a
BADRAWY MRCP Revision

cardiotoxicity
74b
BADRAWY MRCP Revision

Schistosoma haematobium
75a
BADRAWY MRCP Revision

causes haematuria
75b
BADRAWY MRCP Revision

Horner's syndrome -
anhydrosis of head, arm,
trunk =
76a
BADRAWY MRCP Revision

central lesion: stroke,
syringomyelia
76b
BADRAWY MRCP Revision

Chickenpox exposure in
pregnancy - first step?
77a
BADRAWY MRCP Revision

check antibodies
77b
BADRAWY MRCP Revision

CLL - treatment?
78a
BADRAWY MRCP Revision

chlorambucil
78b
BADRAWY MRCP Revision

ADPKD type 1
chromosome
79a
BADRAWY MRCP Revision

chromosome 16 = 85% of
cases
79b
BADRAWY MRCP Revision

Chemo agent associated
with hypomagnesaemia?
80a
BADRAWY MRCP Revision

Cisplatin
80b
BADRAWY MRCP Revision

Rx Infertility in PCOS -
81a
BADRAWY MRCP Revision

clomifene is superior to
metformin
81b
BADRAWY MRCP Revision

JVP: C wave - physiological
correlate
82a
BADRAWY MRCP Revision

closure of the tricuspid
valve
82b
BADRAWY MRCP Revision

Episodic eye pain,
lacrimation, nasal
stuffiness occurring daily -
?diagnosis
83a
BADRAWY MRCP Revision

cluster headache
83b
BADRAWY MRCP Revision

Burkitt's lymphoma - gene
translocation?
84a
BADRAWY MRCP Revision

c-myc
84b
BADRAWY MRCP Revision

Animal bite treatment
85a
BADRAWY MRCP Revision

co-amoxiclav
85b
BADRAWY MRCP Revision

Drug metabolism - phase II
components?
86a
BADRAWY MRCP Revision

conjugation
86b
BADRAWY MRCP Revision

Viagra contraindications
87a
BADRAWY MRCP Revision

contraindicated by nitrates
and nicorandil
87b
BADRAWY MRCP Revision

Main indication for HRT?
88a
BADRAWY MRCP Revision

control of vasomotor
symptoms
88b
BADRAWY MRCP Revision

First line investigation for
PE according to current
BTS guidelines?
89a
BADRAWY MRCP Revision

CTPA
89b
BADRAWY MRCP Revision

hypokalaemic metabolic
alkalosis - endocrine
condition?
90a
BADRAWY MRCP Revision

Cushing's syndrome
90b
BADRAWY MRCP Revision

Hemiballism (involuntary,
sudden, jerking
movements) = caused by?
91a
BADRAWY MRCP Revision

damage to the subthalamic
nucleus
91b
BADRAWY MRCP Revision

Acute myeloid leukaemia -
poor prognosis
92a
BADRAWY MRCP Revision

deletion of chromosome 5
or 7
92b
BADRAWY MRCP Revision

Most common psychiatric
problem in Parkinson's
disease?
93a
BADRAWY MRCP Revision

depression
93b
BADRAWY MRCP Revision

Investigation for Carcinoid
94a
BADRAWY MRCP Revision

Diagnosis: urinary 5-HIAA
94b
BADRAWY MRCP Revision

Adenosine interactions
95a
BADRAWY MRCP Revision

dipyridamole enhances
effect - aminophylline
reduces effect
95b
BADRAWY MRCP Revision

Dystrophia myotonica -
DM1 CFs
96a
BADRAWY MRCP Revision

DM1 - distal weakness
initially - autosomal
dominant - diabetes -
dysarthria
96b
BADRAWY MRCP Revision

Restless leg syndrome -
management
97a
BADRAWY MRCP Revision

dopamine agonists such as
ropinirole
97b
BADRAWY MRCP Revision

Change to steroid dose in
people on long term tx if
intercurrent illness?
98a
BADRAWY MRCP Revision

Double doses
98b
BADRAWY MRCP Revision

Rheumatoid arthritis -
HLA association?
99a
BADRAWY MRCP Revision

DR4
99b
BADRAWY MRCP Revision

HRT: unopposed oestrogen
increases risk of?
100a
BADRAWY MRCP Revision

endometrial cancer
100b
BADRAWY MRCP Revision

Bosentan - MoA, uses?
101a
BADRAWY MRCP Revision

endothelin-1 receptor
antagonist used if negative
response to acute
vasodilator testing in
pulmonary hypertension
101b
BAD...

Pemphigus vulgaris key
features?
102a
BADRAWY MRCP Revision

Epidermal, desmoglein 3,
involves mucosa, flaccid
non-pruritic blisters,
younger people
102b
BADRAWY MRCP Revision

Head injury followed by
lucid interval?
103a
BADRAWY MRCP Revision

Epidural haematoma
103b
BADRAWY MRCP Revision

Zollinger-Ellison syndrome
- CFs
104a
BADRAWY MRCP Revision

epigastric pain and
diarrhoea
104b
BADRAWY MRCP Revision

Key contraindication to
buproprion?
105a
BADRAWY MRCP Revision

epilepsy
105b
BADRAWY MRCP Revision

Ciclosporin side-effects
106a
BADRAWY MRCP Revision

everything is increased -
fluid, BP, K+, hair, gums,
glucose
106b
BADRAWY MRCP Revision

Activated protein C
resistance =
107a
BADRAWY MRCP Revision

Factor V Leiden, the most
common inherited
thrombophilia
107b
BADRAWY MRCP Revision

Diabetes diagnosis:
108a
BADRAWY MRCP Revision

fasting > 7.0, random > 11.1
- if asymptomatic need two
readings
HbA1c of 6.5% or greater is
now diagnostic (WHO 2011)
108...

investigation of choice for
upper airway compression
109a
BADRAWY MRCP Revision

Flow volume loop
109b
BADRAWY MRCP Revision

Common antibiotic causes
of cholestasis
110a
BADRAWY MRCP Revision

Flucloxacillin + co-
amoxiclav
110b
BADRAWY MRCP Revision

Ethylene glycol toxicity
management -
111a
BADRAWY MRCP Revision

fomepizole. Also ethanol /
haemodialysis
111b
BADRAWY MRCP Revision

Benzodiazepines enhance
the effect of which
neurotransmitter?
112a
BADRAWY MRCP Revision

GABA, the main inhibitory
neurotransmitter
112b
BADRAWY MRCP Revision

Signet ring cells =
113a
BADRAWY MRCP Revision

Gastric adenocarcinoma
113b
BADRAWY MRCP Revision

Screening for
haemochromatosis -
114a
BADRAWY MRCP Revision

general population:
transferrin saturation >
ferritin - family members:
HFE genetic testing
114b
BADRAWY MRCP Revision

SSRI + NSAID interaction?
115a
BADRAWY MRCP Revision

GI bleeding risk - give a
PPI
115b
BADRAWY MRCP Revision

Tricyclic overdose - rx
116a
BADRAWY MRCP Revision

give IV bicarbonate
116b
BADRAWY MRCP Revision

ITP - rx
117a
BADRAWY MRCP Revision

give oral prednisolone
117b
BADRAWY MRCP Revision

PHaeochromocytoma -
118a
BADRAWY MRCP Revision

give PHenoxybenzamine
before beta-blockers
118b
BADRAWY MRCP Revision

Exenatide MoA
119a
BADRAWY MRCP Revision

Glucagon-like peptide-1
(GLP-1) mimetic
119b
BADRAWY MRCP Revision

Philadelphia translocation
and prognosis?
120a
BADRAWY MRCP Revision

good prognosis in CML,
poor prognosis in AML +
ALL
120b
BADRAWY MRCP Revision

Absence seizures prognosis
121a
BADRAWY MRCP Revision

good: 90-95% become
seizure free in adolescence
121b
BADRAWY MRCP Revision

Bronchiectasis: most
common organism?
122a
BADRAWY MRCP Revision

Haemophilus influenzae
122b
BADRAWY MRCP Revision

Cyclophosphamide SE:
123a
BADRAWY MRCP Revision

haemorrhagic cystitis -
prevent with mesna
123b
BADRAWY MRCP Revision

Genital ulcers - painful:
124a
BADRAWY MRCP Revision

herpes >> chancroid
124b
BADRAWY MRCP Revision

CT head showing temporal
lobe changes - think what?
125a
BADRAWY MRCP Revision

herpes simplex
encephalitis,temporoparietal
attentuation -
subacute onset i.e. Several
days.
125b
BADRAWY MRCP Revision

most common cause of
sudden cardiac death in the
young
126a
BADRAWY MRCP Revision

HOCM
126b
BADRAWY MRCP Revision

U waves on ECG
127a
BADRAWY MRCP Revision

Hypokalaemia -
127b
BADRAWY MRCP Revision

Liddle's syndrome:
128a
BADRAWY MRCP Revision

hypokalaemia +
hypertension
128b
BADRAWY MRCP Revision

Hashimoto's thyroiditis key
features?
129a
BADRAWY MRCP Revision

hypothyroidism + goitre +
anti-TPO
129b
BADRAWY MRCP Revision

Asymmetrical symptoms in
PD suggest what cause?
130a
BADRAWY MRCP Revision

Idiopathic Parkinson's
130b
BADRAWY MRCP Revision

NSTEMI/unstable angina
Rx. 6 month mortality risk
>1.5% vs 6m risk >3%
131a
BADRAWY MRCP Revision

if > 1.5% clopidogrel for 12
months - if > 3%
angiography within 96
hours
131b
BADRAWY MRCP Revision

Primary biliary cirrhosis -
the M rule mnemonic?
132a
BADRAWY MRCP Revision

IgM - anti-Mitochondrial
antibodies, M2 subtype -
Middle aged females
132b
BADRAWY MRCP Revision

What is rheumatoid factor?
133a
BADRAWY MRCP Revision

IgM antibody against IgG
133b
BADRAWY MRCP Revision

CLL - investigation of
choice?
134a
BADRAWY MRCP Revision

immunophenotyping
134b
BADRAWY MRCP Revision

Nicotinic acid MoA
135a
BADRAWY MRCP Revision

increases HDL levels
135b
BADRAWY MRCP Revision

Essential tremor:
inheritance, aggravants /
relievants
136a
BADRAWY MRCP Revision

Inheritance: AD
Aggravants: Arms
outstretched
Relievants: Alcohol,
propanolol
136b
BADRAWY MRCP Revision

Ciclosporin + tacrolimus -
MOA:
137a
BADRAWY MRCP Revision

inhibit calcineurin thus
decreasing IL-2
137b
BADRAWY MRCP Revision

Statins - MoA?
138a
BADRAWY MRCP Revision

inhibit HMG-CoA
reductase, the rate-limiting
enzyme in hepatic
cholesterol synthesis
138b
BADRAWY MRCP Revision

Bisphosphonates MoA
139a
BADRAWY MRCP Revision

inhibit osteoclasts,prevent
steroid incduced
osteoperosis
(vitamin D also).
139b
BADRAWY MRCP Revision

Clopidogrel MoA:
140a
BADRAWY MRCP Revision

inhibits ADP binding to
platelet receptors
140b
BADRAWY MRCP Revision

Dipyridamole - MoA
141a
BADRAWY MRCP Revision

inhibits phosphodiesterase
141b
BADRAWY MRCP Revision

Digoxin - MoA
142a
BADRAWY MRCP Revision

inhibits the Na+/K+
ATPase pump
142b
BADRAWY MRCP Revision

Isoniazid SEs:
143a
BADRAWY MRCP Revision

inhibits the P450 system,
causes peripheral
neuropathy
143b
BADRAWY MRCP Revision

Allopurinol MoA
144a
BADRAWY MRCP Revision

inhibits xanthine oxidase
144b
BADRAWY MRCP Revision

Symptom control in non-
CF bronchiectasis?
145a
BADRAWY MRCP Revision

inspiratory muscle training
+ postural drainage
145b
BADRAWY MRCP Revision

Complete heart block
following an ANterior MI -
?pacing
146a
BADRAWY MRCP Revision

is AN indication for pacing,
unlike with an inferior MI
146b
BADRAWY MRCP Revision

Streptococcus pneumoniae
147a
BADRAWY MRCP Revision

is associated with cold
sores
147b
BADRAWY MRCP Revision

Streptococcus bovis
endocarditis
148a
BADRAWY MRCP Revision

is associated with
colorectal cancer
148b
BADRAWY MRCP Revision

Legionella pneumophilia
149a
BADRAWY MRCP Revision

is best diagnosed by the
urinary antigen test
149b
BADRAWY MRCP Revision

Complete heart block
following an INferior MI - ?
pacing
150a
BADRAWY MRCP Revision

Is Not an indication for
pacing, unlike with an
anterior MI
150b
BADRAWY MRCP Revision

Most common cause of
occupational asthma?
151a
BADRAWY MRCP Revision

Isocyanates
151b
BADRAWY MRCP Revision

Lichen sclerosus:
152a
BADRAWY MRCP Revision

itchy white spots typically
seen on the vulva of elderly
women
152b
BADRAWY MRCP Revision

Polycythaemia rubra vera -
genetic cause?
153a
BADRAWY MRCP Revision

JAK2 mutation
153b
BADRAWY MRCP Revision

Hypertension - step 4 rx?
154a
BADRAWY MRCP Revision

K+ < 4.5 then
spironolactone - K+ > 4.5
then higher-dose thiazide-
like diuretic
154b
BADRAWY MRCP Revision

Pneumonia in an alcoholic
- pathogen?
155a
BADRAWY MRCP Revision

Klebsiella
155b
BADRAWY MRCP Revision

BTS COPD: breathless
despite PRN inhalers, and
FEV1 < 50%
156a
BADRAWY MRCP Revision

LABA + ICS or LAMA
156b
BADRAWY MRCP Revision

BTS COPD: breathless
despite PRN inhalers, and
FEV1 > 50%:
157a
BADRAWY MRCP Revision

LABA or LAMA
157b
BADRAWY MRCP Revision

Polymorphic eruption of
pregnancy - CFs?
158a
BADRAWY MRCP Revision

Last trimester, may see
vesicles, but no blistering
158b
BADRAWY MRCP Revision

Cerebellar signs,
contralateral sensory loss &
ipsilateral Horner's =
159a
BADRAWY MRCP Revision

Lateral medullary
syndrome - PICA lesion -
159b
BADRAWY MRCP Revision

Mucocutaneous ulceration
following travel - key
differential?
160a
BADRAWY MRCP Revision

Leishmania brasiliensis
160b
BADRAWY MRCP Revision

Most common presenting
symptom in myelofibrosis?
161a
BADRAWY MRCP Revision

lethargy
161b
BADRAWY MRCP Revision

Safest TCA in overdosage?
162a
BADRAWY MRCP Revision

Lofepramine
162b
BADRAWY MRCP Revision

Second heart sound (S2) -
loud, soft, fixed split,
reversed split?
163a
BADRAWY MRCP Revision

loud: hypertension - soft:
AS - fixed split: ASD -
reversed split: LBBB
163b
BADRAWY MRCP Revision

ESR in polycythaemia
rubra vera
164a
BADRAWY MRCP Revision

low
164b
BADRAWY MRCP Revision

Oxygen dissociation curve -
shifts Left?
165a
BADRAWY MRCP Revision

Lower oxygen delivery -
Lower acidity, temp, 2-3
DPG - also HbF,
carboxy/methaemoglobin -
165b
BADRAWY MRCP Revision

Most common lung cancer
type in non-smokers?
166a
BADRAWY MRCP Revision

Lung adenocarcinoma -
peripheral lesion
166b
BADRAWY MRCP Revision

Gallop rhythm (S3) is an
early sign of?
167a
BADRAWY MRCP Revision

LVF
167b
BADRAWY MRCP Revision

Hodgkin's lymphoma - best
prognosis =
168a
BADRAWY MRCP Revision

lymphocyte predominant
168b
BADRAWY MRCP Revision

Patients with Sjogren's
syndrome have an
increased risk of which
malignancy?
169a
BADRAWY MRCP Revision

lymphoid malignancies
169b
BADRAWY MRCP Revision

Rx for Mycoplasma
pneumonia
170a
BADRAWY MRCP Revision

Macrolides. If allergic
=doxycycline
170b
BADRAWY MRCP Revision

Eclampsia - first-line
treatment
171a
BADRAWY MRCP Revision

magnesium sulphate
171b
BADRAWY MRCP Revision

Sarcoidosis prognosis?
172a
BADRAWY MRCP Revision

Majority of patients get
better without treatment
172b
BADRAWY MRCP Revision

PTH level in primary
hyperparathyroidism
173a
BADRAWY MRCP Revision

may be normal
173b
BADRAWY MRCP Revision

TNF-#alpha# inhibitors
174a
BADRAWY MRCP Revision

may reactivate TB
174b
BADRAWY MRCP Revision

Choosing prosthetic heart
valves
175a
BADRAWY MRCP Revision

mechanical valves last
longer and tend to be given
to younger patients
175b
BADRAWY MRCP Revision

Prolactinoma management
-medical or surgical?
176a
BADRAWY MRCP Revision

medical therapy is almost
always first-line
176b
BADRAWY MRCP Revision

Autosomal recessive
conditions tend to be ??
with what exceptions?
177a
BADRAWY MRCP Revision

Metabolic. Exception =
inherited ataxias
177b
BADRAWY MRCP Revision

Acne rosacea treatment: -
178a
BADRAWY MRCP Revision

mild/moderate: topical
metronidazole -
severe/resistant: oral
tetracycline
178b
BADRAWY MRCP Revision

Kearns-Sayre syndrome -
179a
BADRAWY MRCP Revision

mitochondrial inheritance -
onset < 20-years-old -
external ophthalmoplegia -
retinitis pigmentosa
179b
BADRAWY MRCP Revis...

Common topical steroids
and their potency?
180a
BADRAWY MRCP Revision

moderate: Clobetasone
butyrate 0.05% - potent:
Betamethasone valerate 0.1%
- very potent: Clobetasol
propionate 0.05%
180b...

Magnesium sulphate -
monitoring
181a
BADRAWY MRCP Revision

monitor reflexes +
respiratory rate
181b
BADRAWY MRCP Revision

Cetuximab - MoA?
182a
BADRAWY MRCP Revision

monoclonal antibody
against the epidermal
growth factor receptor
182b
BADRAWY MRCP Revision

Trastuzumab (Herceptin) -
183a
BADRAWY MRCP Revision

monoclonal antibody that
acts on the HER2/neu
receptor
183b
BADRAWY MRCP Revision

Anorexia features -
184a
BADRAWY MRCP Revision

most things low - G's and
C's raised: growth
hormone, glucose, salivary
glands, cortisol,
cholesterol, carotinaemia
184b
B...

Rises first following MI?
185a
BADRAWY MRCP Revision

Myoglobin
185b
BADRAWY MRCP Revision

Hypercholesterolaemia
rather than
hypertriglyceridaemia:
186a
BADRAWY MRCP Revision

nephrotic syndrome,
cholestasis,
hypothyroidism
186b
BADRAWY MRCP Revision

Signs suggesting TTP
rather than HUS?
187a
BADRAWY MRCP Revision

Neuro signs and purpura
point towards TTP
187b
BADRAWY MRCP Revision

Motor neuron disease -
treatment:
188a
BADRAWY MRCP Revision

NIV is better than riluzole
188b
BADRAWY MRCP Revision

AF treatment: young man,
no TIA or risk factors,
189a
BADRAWY MRCP Revision

no treatment is now
preferred to aspirin
189b
BADRAWY MRCP Revision

Hodgkin's lymphoma -
most common type =
190a
BADRAWY MRCP Revision

nodular sclerosing
190b
BADRAWY MRCP Revision

Renal tubular acidosis -
anion gap?
191a
BADRAWY MRCP Revision

normal anion gap
191b
BADRAWY MRCP Revision

Urinary incontinence + gait
abnormality + dementia.
Diagnosis?
192a
BADRAWY MRCP Revision

normal pressure
hydrocephalus
192b
BADRAWY MRCP Revision

Rx metastatic bone pain
193a
BADRAWY MRCP Revision

NSAIDs, bisphosphonates
or radiotherapy
193b
BADRAWY MRCP Revision

Acromegaly diagnosis?
194a
BADRAWY MRCP Revision

oral glucose tolerance with
growth hormone
measurements
194b
BADRAWY MRCP Revision

Cushing's syndrome - best
test to diagnose?
195a
BADRAWY MRCP Revision

overnight dexamethasone
suppression test
195b
BADRAWY MRCP Revision

Drug metabolism - phase I
components?
196a
BADRAWY MRCP Revision

oxidation, reduction,
hydrolysis
196b
BADRAWY MRCP Revision

Antiphospholipid
syndrome: APPT, PLTs
197a
BADRAWY MRCP Revision

Paradoxically prolonged
APTT + low platelets
197b
BADRAWY MRCP Revision

Progressive supranuclear
palsy CFs?
198a
BADRAWY MRCP Revision

Absent voluntary downward
gaze, normal dolls eye . i.e.
Occulomotor nuclei intact,
supranuclear Pathology.
parkinsonism
19...

SSRI with high incidence of
discontinuation symptoms?
199a
BADRAWY MRCP Revision

Paroxetine
199b
BADRAWY MRCP Revision

Collapsing pulse - which
congenital heart defect?
200a
BADRAWY MRCP Revision

Patent ductus arteriosus -
200b
BADRAWY MRCP Revision

Vincristine - important SE?
201a
BADRAWY MRCP Revision

peripheral neuropathy
201b
BADRAWY MRCP Revision

Drugs with zero-order
(saturation) kinetics -
202a
BADRAWY MRCP Revision

phenytoin - alcohol
202b
BADRAWY MRCP Revision

Causes of gingival
hyperplasia?
203a
BADRAWY MRCP Revision

phenytoin, ciclosporin,
calcium channel blockers
and AML
203b
BADRAWY MRCP Revision

TTP first-line Rx?
204a
BADRAWY MRCP Revision

Plasma exchange
204b
BADRAWY MRCP Revision

Painful third nerve palsy -
key differential?
205a
BADRAWY MRCP Revision

posterior communicating
artery aneurysm
205b
BADRAWY MRCP Revision

Horner's syndrome -
anhydrosis absent =
206a
BADRAWY MRCP Revision

post-ganglionic lesion:
carotid artery
206b
BADRAWY MRCP Revision

Rx Minimal change
glomerulonephritis?
207a
BADRAWY MRCP Revision

prednisolone
207b
BADRAWY MRCP Revision

Horner's syndrome -
anhydrosis of just face =
208a
BADRAWY MRCP Revision

pre-ganglionic lesion:
Pancoast's, cervical rib
208b
BADRAWY MRCP Revision

Causes of raised prolactin?
209a
BADRAWY MRCP Revision

pregnancy - prolactinoma -
physiological - polycystic ovarian
syndrome - primary
hypothyroidism -
phenothiazines,
metoclop...

Taxanes (e.g. Docetaxel)
MoA?
210a
BADRAWY MRCP Revision

prevent microtubule
disassembly
210b
BADRAWY MRCP Revision

Infective endocarditis -
strongest risk factor
211a
BADRAWY MRCP Revision

previous episode of
infective endocarditis
211b
BADRAWY MRCP Revision

Ptosis + dilated pupil vs
Ptosis + constricted pupil
212a
BADRAWY MRCP Revision

Ptosis + dilated pupil = 3rd
nerve palsy; Ptosis +
constricted pupil =
Horner's
212b
BADRAWY MRCP Revision

Lichen - planus:
213a
BADRAWY MRCP Revision

purple, pruritic, papular,
polygonal rash on flexor
surfaces. Wickham's striae
over surface. Oral
involvement common
213b
...

Oxygen dissociation curve -
shifts Right?
214a
BADRAWY MRCP Revision

Raised oxygen delivery -
Raised acidity, temp, 2-3
DPG
214b
BADRAWY MRCP Revision

HbA1C - when to recheck
after change in therapy?
215a
BADRAWY MRCP Revision

recheck after 2-3 months
215b
BADRAWY MRCP Revision

Inferior MI -
216a
BADRAWY MRCP Revision

right coronary artery lesion
216b
BADRAWY MRCP Revision

Farmers lung pathogen
217a
BADRAWY MRCP Revision

Saccharopolyspora
rectivirgula
217b
BADRAWY MRCP Revision

Erythema nodosum is
associated with a good
prognosis in what systemic
condition?
218a
BADRAWY MRCP Revision

sarcoidosis
218b
BADRAWY MRCP Revision

Combined B- and T-cell
disorders
219a
BADRAWY MRCP Revision

SCID WAS ataxic (SCID,
Wiskott-Aldrich syndrome,
ataxic telangiectasia)
219b
BADRAWY MRCP Revision

Pulsus alternans?
220a
BADRAWY MRCP Revision

seen in left ventricular
failure
220b
BADRAWY MRCP Revision

HOCM - poor prognostic
factor on echo =
221a
BADRAWY MRCP Revision

septal wall thickness of >
3cm
221b
BADRAWY MRCP Revision

Detecting occupational
asthma?
222a
BADRAWY MRCP Revision

Serial peak flow
measurements at work and
at home
222b
BADRAWY MRCP Revision

Mycoplasma diagnosis
223a
BADRAWY MRCP Revision

Serology
223b
BADRAWY MRCP Revision

Dx Addison's disease
224a
BADRAWY MRCP Revision

short synacthen test
224b
BADRAWY MRCP Revision

Epilepsy medication: first-
line - generalised seizure:
225a
BADRAWY MRCP Revision

sodium valproate -
225b
BADRAWY MRCP Revision

Syringomyelia - CFs?
226a
BADRAWY MRCP Revision

spinothalamic sensory loss
(pain and temperature)
226b
BADRAWY MRCP Revision

Asthma diagnosis - first
line investigation in
intermediate probability?
227a
BADRAWY MRCP Revision

Spirometry
227b
BADRAWY MRCP Revision

Paraneoplastic features of
lung cancer - squamous cell
vs small cell?
228a
BADRAWY MRCP Revision

squamous cell: PTHrp,
clubbing, HPOA - small
cell: ADH, ACTH, Lambert-
Eaton syndrome
228b
BADRAWY MRCP Revision

Pneumonia following
influenza - pathogen?
229a
BADRAWY MRCP Revision

Staphylococcus aureus
pneumonia
229b
BADRAWY MRCP Revision

Most common cause of
endocarditis if < 2 months
post valve surgery
230a
BADRAWY MRCP Revision

Staphylococcus
epidermidis
230b
BADRAWY MRCP Revision

Asthma diagnosis - first
line investigation in high
probability?
231a
BADRAWY MRCP Revision

Start treatment
231b
BADRAWY MRCP Revision

Infective endocarditis -
good prognosis
232a
BADRAWY MRCP Revision

streptococcal infection
232b
BADRAWY MRCP Revision

Most common cause of
endocarditis
233a
BADRAWY MRCP Revision

Streptococcus viridans
233b
BADRAWY MRCP Revision

Antipsychotics in the
elderly -> risk of?
234a
BADRAWY MRCP Revision

stroke and VTE
234b
BADRAWY MRCP Revision

Autosomal dominant
conditions tend to be ?? -
with what exceptions?
235a
BADRAWY MRCP Revision

Structural. Exceptions =
hyperlipidaemia type II,
hypokalaemic periodic
paralysis
235b
BADRAWY MRCP Revision

Cluster headache - acute
treatment
236a
BADRAWY MRCP Revision

subcutaneous sumatriptan
+ 100% O2
236b
BADRAWY MRCP Revision

Bullous pemphigoid key
features?
237a
BADRAWY MRCP Revision

Subepidermal,
hemidesmosomal BP
antigens, rarely involves
mucosa, tense pruritic
blisters, older people
237b
BADRAWY MRCP ...

Diagnosing insulinoma?
238a
BADRAWY MRCP Revision

supervised prolonged
fasting
238b
BADRAWY MRCP Revision

Cryptosporidium diarrhoea
Rx
239a
BADRAWY MRCP Revision

Supportive therapy
239b
BADRAWY MRCP Revision

Contraindications to lung
cancer surgery
240a
BADRAWY MRCP Revision

SVC obstruction, FEV < 1.5,
MALIGNANT pleural
effusion, and vocal cord
paralysis
240b
BADRAWY MRCP Revision

Reason for ^sweating in
acromegaly
241a
BADRAWY MRCP Revision

sweat gland hypertrophy
241b
BADRAWY MRCP Revision

Alcohol withdrawal time to
symptoms/signs
242a
BADRAWY MRCP Revision

symptoms: 6-12 hours -
seizures: 36 hours -
delirium tremens: 72 hours
242b
BADRAWY MRCP Revision

Genital ulcers - painless:
243a
BADRAWY MRCP Revision

syphilis >
lymphogranuloma
venereum + granuloma
inguinale
243b
BADRAWY MRCP Revision

Philadelphia translocation?
244a
BADRAWY MRCP Revision

t(9;22)
244b
BADRAWY MRCP Revision

Congenital heart disease -
cyanotic - most common
cause:
245a
BADRAWY MRCP Revision

TGA most common at
birth, Fallot's most
common overall -
245b
BADRAWY MRCP Revision

Melanoma: single most
important prognostic factor
246a
BADRAWY MRCP Revision

the invasion depth of the
tumour
246b
BADRAWY MRCP Revision

Diuretic cause of
hypercalcaemia?
247a
BADRAWY MRCP Revision

Thiazides
247b
BADRAWY MRCP Revision

Disproportionate
microcytic anaemia -
think?
248a
BADRAWY MRCP Revision

think beta-thalassaemia
trait
248b
BADRAWY MRCP Revision

Hashimoto's thyroiditis is
associated with which
malignancy?
249a
BADRAWY MRCP Revision

thyroid lymphoma
249b
BADRAWY MRCP Revision

Impetigo - rx
250a
BADRAWY MRCP Revision

topical fusidic acid --> oral
flucloxacillin / topical
retapamulin
250b
BADRAWY MRCP Revision

Chlamydia - treatment
251a
BADRAWY MRCP Revision

treat with azithromycin or
doxycycline
251b
BADRAWY MRCP Revision

JVP: giant v waves
252a
BADRAWY MRCP Revision

tricuspid regurgitation
252b
BADRAWY MRCP Revision

Associations in
mesangiocapillary /
membranoproliferative
GN. Type 1 vs Type 2
253a
BADRAWY MRCP Revision

type 1: cryoglobulinaemia,
hepatitis C - type 2: partial
lipodystrophy
253b
BADRAWY MRCP Revision

Aortic dissection - Type A
254a
BADRAWY MRCP Revision

type A - ascending aorta -
control BP(IV labetalol) +
surgery
254b
BADRAWY MRCP Revision

Aortic dissection - Type B
255a
BADRAWY MRCP Revision

type B - descending aorta -
control BP(IV labetalol), no
surgery
255b
BADRAWY MRCP Revision

Diagnosing systemic
mastocytosis?
256a
BADRAWY MRCP Revision

Urinary histamine
256b
BADRAWY MRCP Revision

Vigabatrin - important SE?
257a
BADRAWY MRCP Revision

V for Vigabatrin - V for
Visual field defects
257b
BADRAWY MRCP Revision

Ventricular tachycardia -
which antiarrhythmic is
contraindicated?
258a
BADRAWY MRCP Revision

verapamil
258b
BADRAWY MRCP Revision

macrophages containing
Periodic acid-Schiff (PAS)
granules
259a
BADRAWY MRCP Revision

Whipple's disease jejunal
biopsy
259b
BADRAWY MRCP Revision

PCI - biggest RF for stent
thrombosis?
260a
BADRAWY MRCP Revision

withdrawal of antiplatelets
260b
BADRAWY MRCP Revision

Alport's syndrome
inheritance
261a
BADRAWY MRCP Revision

X-linked dominant (in the
majority)
261b
BADRAWY MRCP Revision

Keloid scars - more
common in who and what
body part?
262a
BADRAWY MRCP Revision

young, black, male adults
on the sternum
262b
BADRAWY MRCP Revision

Ankylosing spondylitis: CFs
263a
BADRAWY MRCP Revision

Features - the 'A's
• Apical fibrosis (CXR)
• Anterior uveitis
• Aortic regurgitation
• Achilles tendonitis
• AV node bloc...

Septic arthritis - most
common organism?
264a
BADRAWY MRCP Revision

Staphylococcus aureus
264b
BADRAWY MRCP Revision

Low levels of which type of
complement are associated
with SLE?
265a
BADRAWY MRCP Revision

C3, C4a and C4b
265b
BADRAWY MRCP Revision

What should you check
before starting
azathioprine?
266a
BADRAWY MRCP Revision

Check thiopurine
methyltransferase
deficiency (TPMT) before
treatment
266b
BADRAWY MRCP Revision

When to start allopurinol
in gout?
267a
BADRAWY MRCP Revision

>= 2 attacks in 12 month
period.
267b
BADRAWY MRCP Revision

Which cytokine is most
important in
pathophysiology of
rheumatoid arthritis?
268a
BADRAWY MRCP Revision

TNF
268b
BADRAWY MRCP Revision

Nitric oxide - key effects
269a
BADRAWY MRCP Revision

Vasodilation - mainly
venodilation
Inhibits platelet
aggregation
269b
BADRAWY MRCP Revision

Superiority vs equivalence
vs non-inferiority. What
sample sizes?
270a
BADRAWY MRCP Revision

Superiority trial --> large
sample size needed.
270b
BADRAWY MRCP Revision

Clotting factors affected by
warfarin?
271a
BADRAWY MRCP Revision

Mnemonic = 1972 (Simon)
- 10, 9, 7 and 2.
271b
BADRAWY MRCP Revision

Adrenal cortex - what part
releases what?
272a
BADRAWY MRCP Revision

Mnemonic GFR - ACD
1) Glomerulosa (outer):
Aldosterone
2) Fasciculata (middle): Cortisol
3) Reticularis (on inside): DHEA
...

Obese T2DM with
abnormal LFTs - think of
what disease?
273a
BADRAWY MRCP Revision

non-alcoholic fatty liver
disease
273b
BADRAWY MRCP Revision

EBV-associated
malignancies
274a
BADRAWY MRCP Revision

Burkitt's lymphoma
Hodgkin's lymphoma
nasopharyngeal carcinoma
HIV-associated central nervous
system lymphomas
Hairy leuko...

Associations between
hypermetropia/myopia and
glaucoma?
275a
BADRAWY MRCP Revision

Acute angle closure glaucoma
is associated with
hypermetropia, where as
primary open-angle glaucoma
is associated with myo...

Antiphospholipid
syndrome: key triad of
features
276a
BADRAWY MRCP Revision

arterial/venous
thrombosis, miscarriage,
livedo reticularis
276b
BADRAWY MRCP Revision

Types of cells seen in CLL?
277a
BADRAWY MRCP Revision

CLL is caused by a
monoclonal proliferation of
B-cell lymphocytes
277b
BADRAWY MRCP Revision

Atrial natriuretic peptide -
effect on vessels?
278a
BADRAWY MRCP Revision

Atrial natriuretic peptide -
powerful vasodilator
278b
BADRAWY MRCP Revision

Most common cause of
primary
hyperaldosteronism
279a
BADRAWY MRCP Revision

Bilateral idiopathic adrenal
hyperplasia is the most
common cause of primary
hyperaldosteronism
279b
BADRAWY MRCP Revision

Obesity - NICE bariatric
referral cut offs
280a
BADRAWY MRCP Revision

NICE bariatric referral cut-
offs
with risk factors (T2DM, BP
etc): > 35 kg/m^2
no risk factors: > 40 kg/m^2
280b
BADRAWY ...

CT most commonly
associated with PBC
281a
BADRAWY MRCP Revision

Sjogren's syndrome
281b
BADRAWY MRCP Revision

How names of ART drugs
relate to function
282a
BADRAWY MRCP Revision

HIV drugs, rule of thumb:
NRTIs end in 'ine'
Pis: end in 'vir'
NNRTIs: nevirapine,
efavirenz
282b
BADRAWY MRCP Revision

Interpreting the ACR
results
283a
BADRAWY MRCP Revision

in non-diabetics an ACR greater than 30
mg/mmol is considered clinically
significant proteinuria
in diabetics microalbumin...

Which antiepileptic is safe
in breast feeding?
284a
BADRAWY MRCP Revision

Breast feeding is acceptable
with nearly all anti-
epileptic drugs
284b
BADRAWY MRCP Revision

ATN or prerenal uraemia?
285a
BADRAWY MRCP Revision

In prerenal uraemia think
of the kidneys holding on
to sodium to preserve
volume
285b
BADRAWY MRCP Revision

Renal stones on x-ray
286a
BADRAWY MRCP Revision

cystine stones: semi-
opaque
urate + xanthine stones:
radio-lucent
286b
BADRAWY MRCP Revision

Isoretinoin adverse effects?
287a
BADRAWY MRCP Revision

teratogenicity - females MUST be
taking contraception
low mood
dry eyes and lips
raised triglycerides
hair thinning
nose b...

An important and common
interaction with statins?
288a
BADRAWY MRCP Revision

Statins +
erythromycin/clarithromycin
- an important and common
interaction
288b
BADRAWY MRCP Revision

Low CSF glucose but viral
aetiology in meningitis?
289a
BADRAWY MRCP Revision

Mumps meningitis is
associated with a low
glucose in up to a third of
patients
289b
BADRAWY MRCP Revision

Type of bladder cancer
association with
schistosomiasis
290a
BADRAWY MRCP Revision

SchistoSomiaSiS is a risk
factor for SquamouS cell
bladder cancer
290b
BADRAWY MRCP Revision

%tage of people with Hep C
developing cirrhosis?
291a
BADRAWY MRCP Revision

Liver cirrhosis will develop
in around 20-30% of
patients over 20-30 years
291b
BADRAWY MRCP Revision

Rash on buttocks
292a
BADRAWY MRCP Revision

Dermatitis herpetiformis
(coeliac dx).
292b
BADRAWY MRCP Revision

Obese woman,
papilledema/headache
293a
BADRAWY MRCP Revision

Benign Intercanial
Hypertention.
293b
BADRAWY MRCP Revision

Drug induced pneumonitis
294a
BADRAWY MRCP Revision

methotrexate or
amiodarone.
294b
BADRAWY MRCP Revision

foreign travel, macpap
rash/flu like illnes
295a
BADRAWY MRCP Revision

HIV acute.
295b
BADRAWY MRCP Revision

Splenectomy
296a
BADRAWY MRCP Revision

need pneumococcal vaccine
AT LEAST 2 weeks pre-op
and for life.
296b
BADRAWY MRCP Revision

Primary
hrperparathyroidism
297a
BADRAWY MRCP Revision

high Ca, normal/low PO4,
normal/high PTH (in
elderly).
297b
BADRAWY MRCP Revision

Middle aged man with
KNEE arthritis
298a
BADRAWY MRCP Revision

gonococcal sepsis (older
people ➜ Staph).
298b
BADRAWY MRCP Revision

Sarcoidosis, erythema
nodosum, arthropathy
299a
BADRAWY MRCP Revision

Loffgrens syndrome
benign, no Rx needed or
NSAIDs
299b
BADRAWY MRCP Revision

TREMOR postural, slow
progression,titubation,
300a
BADRAWY MRCP Revision

benign essential TREMOR
AutDom.
300b
BADRAWY MRCP Revision

Contraindications lung
Surgery
301a
BADRAWY MRCP Revision

FEV dec bp 130/90, Ace
inhibitors (if proteinuria
analgesic induced
headache.
301b
BADRAWY MRCP Revision

1.5 cm difference btwn
kidneys
302a
BADRAWY MRCP Revision

Renal artery stenosis ➜
Magnetic resonance
angiogram.
302b
BADRAWY MRCP Revision

Temporal tenderness
303a
BADRAWY MRCP Revision

temporal arteritis ➜
steroids > 90% ischemic
neuropathy, 10%
retinal art occlusion.
303b
BADRAWY MRCP Revision

cluster headache.
304a
BADRAWY MRCP Revision

Severe retroorbital, daily
headache, lacrimation
304b
BADRAWY MRCP Revision

Diagnosis of polyuria
305a
BADRAWY MRCP Revision

water deprivation test, then
DDAVP
305b
BADRAWY MRCP Revision

Causes of villous atrophy
306a
BADRAWY MRCP Revision

coeliac (lymphocytic
infiltrate), Whipples , dec Ig,
lymphoma, trop sprue (Rx
tetracycline).
306b
BADRAWY MRCP Revision

Hepatitis B with general
deterioration
307a
BADRAWY MRCP Revision

hepaocellular carcinoma
307b
BADRAWY MRCP Revision

Albumin normal, total
protein high
308a
BADRAWY MRCP Revision

myeloma (hypercalcemia,
electrophoresis).
308b
BADRAWY MRCP Revision

HBsAg positive, HB DNA
not detectable
309a
BADRAWY MRCP Revision

chornic carirer
309b
BADRAWY MRCP Revision

Aortic Stenosis
310a
BADRAWY MRCP Revision

s2 paradoxical split, length
proportional to severity
310b
BADRAWY MRCP Revision

Loud S1
311a
BADRAWY MRCP Revision

MS, hyperdynamic, short
PR
311b
BADRAWY MRCP Revision

Soft S1
312a
BADRAWY MRCP Revision

immobile MS, MR.
312b
BADRAWY MRCP Revision

Loud S2
313a
BADRAWY MRCP Revision

hypertension, AS
313b
BADRAWY MRCP Revision

Fixed split
314a
BADRAWY MRCP Revision

ASD
314b
BADRAWY MRCP Revision

Opening snap
315a
BADRAWY MRCP Revision

MOBILE MS, severe near
S2
315b
BADRAWY MRCP Revision

HOCM/MVP
316a
BADRAWY MRCP Revision

inc by standing,valsalva,
dec by squating (# all
others)
316b
BADRAWY MRCP Revision

HOCM
317a
BADRAWY MRCP Revision

Sudden death athlete, FH,
Rx. Amiodarone, ICD
317b
BADRAWY MRCP Revision

Guillan Barre syndrome
318a
BADRAWY MRCP Revision

check VITAL CAPACITY.
318b
BADRAWY MRCP Revision

Horners
319a
BADRAWY MRCP Revision

sweating lost in upper face
only - lesion proximal to
common carotid artery.
319b
BADRAWY MRCP Revision

Internuclear
opthalmoplegia
320a
BADRAWY MRCP Revision

medial longitudinal
fasciculus connects CN
nucleus 3-4.
320b
BADRAWY MRCP Revision

Perinauds syndrome
321a
BADRAWY MRCP Revision

dorsal midbrain syndrome,
damaged midrain and superior
colliculus: impaired upgaze (cf
PSNP), lid retraction, convergence
...

Acute red eye
322a
BADRAWY MRCP Revision

acute closed angle
glaucoma >> less common
(ant uveitis, scleritis,
episcleritis, subconjuntival
hemmorrhage).
322b
BADRAW...

Sweats and weight gain
323a
BADRAWY MRCP Revision

insulinoma.
323b
BADRAWY MRCP Revision

Diagnostic test for asthma
324a
BADRAWY MRCP Revision

morning dip in PEFR
>20%.
324b
BADRAWY MRCP Revision

Causes of SIADH
325a
BADRAWY MRCP Revision

chest/cerebral/pancreas Pathology
, porphyria, malignancy, Drugs
(carbamazepine, chlorpropamide,
clofibrate, atipsychotics...

Causes of central DI
326a
BADRAWY MRCP Revision

tumor, infiltration, trauma
326b
BADRAWY MRCP Revision

Causes of Nephrogenic DI
327a
BADRAWY MRCP Revision

Lithium, amphoteracin,
domeclocycline, prologed
hypercalcemia/hypornatremia,
FAMILIAL X linked type
327b
BADRAWY MRCP Revi...

Returned from airline
flight, TIA
328a
BADRAWY MRCP Revision

paradoxical embolus do
TEE.
328b
BADRAWY MRCP Revision

Alcoholic, given glucose
develops nystagmus
329a
BADRAWY MRCP Revision

B1 deficiency (wernickes).
329b
BADRAWY MRCP Revision

Mono-artropathy with
thiazide
330a
BADRAWY MRCP Revision

gout (neg birefringence).
NO ALLOPURINOL for
acute.
330b
BADRAWY MRCP Revision

MC Cause of gout
331a
BADRAWY MRCP Revision

dec urinary excretion
331b
BADRAWY MRCP Revision

Painful 3rd nerve palsy
332a
BADRAWY MRCP Revision

posterior communicating
artery aneurysm till proven
otherwise
332b
BADRAWY MRCP Revision

Late complication of
scleroderma
333a
BADRAWY MRCP Revision

pulmonary hypertention ±
fibrosis
333b
BADRAWY MRCP Revision

Mouth/genital ulcers and
oligarthritis
334a
BADRAWY MRCP Revision

behcets (also eye /SKIN
lesions, DVT)
334b
BADRAWY MRCP Revision

Cavernous sinus syndrome
335a
BADRAWY MRCP Revision

3rd nerve palsy, proptosis,
periorbital swelling, conj
injection
335b
BADRAWY MRCP Revision

Asymetric parkinsons
336a
BADRAWY MRCP Revision

likely to be idiopathic
336b
BADRAWY MRCP Revision

Obese, NIDDM ♀ with
abnormal LFT's
337a
BADRAWY MRCP Revision

NASH
337b
BADRAWY MRCP Revision

Ipsilateral ataxia, Horners,
contralateral loss
pain/temp
338a
BADRAWY MRCP Revision

PICA stroke (lateral
medulary syndrome of
Wallenburg)
338b
BADRAWY MRCP Revision

Distal, asymetric
arthropathy
339a
BADRAWY MRCP Revision

PSORIASIS
339b
BADRAWY MRCP Revision

Episodic headache with
tachycardia
340a
BADRAWY MRCP Revision

Pheochromocytoma
340b
BADRAWY MRCP Revision

Very raised WCC
341a
BADRAWY MRCP Revision

ALWAYS think of
leukemia.
341b
BADRAWY MRCP Revision

Diagnosis of CLL
342a
BADRAWY MRCP Revision

immunophenotyping NOT
cytogenetics, NOT bone
marrow
342b
BADRAWY MRCP Revision

Prognostic factors for AML
343a
BADRAWY MRCP Revision

bm karyotype
(good/poor/standard)
343b
BADRAWY MRCP Revision

Pancytopenia with raised
MCV
344a
BADRAWY MRCP Revision

check B12/folate first
(other causes possible, but
do this FIRST). Often
associayed with phenytoin
use ➜ ↓ folate
344b
...

Anosmia, delayed puberty
345a
BADRAWY MRCP Revision

Kallmans syndrome
(hypogonadotrophic
hypogonadism)
345b
BADRAWY MRCP Revision

Commonest finding in
G6PD hamolysis
346a
BADRAWY MRCP Revision

haemoglobinuria
346b
BADRAWY MRCP Revision

Flank pain,
urinalysis:blood, protein
347a
BADRAWY MRCP Revision

renal vein thrombosis.
Causes: nephrotic
syndrome, RCC, amyloid,
acute pyelonephritis, SLE
,atiphospholipid syndrome
347b
...

Anemia in the elderly
assume
348a
BADRAWY MRCP Revision

GI malignancy
348b
BADRAWY MRCP Revision

Diptheria
349a
BADRAWY MRCP Revision

exudative pharyngitis,
lymphadenopathy, cardio
and neuro toxicity.
349b
BADRAWY MRCP Revision

Indurated plaques on
cheeks, scarring alopecia,
hyperkeratosis over hair
follicles
350a
BADRAWY MRCP Revision

Discoid LUPUS
350b
BADRAWY MRCP Revision

Wt loss, malabsoption, inc
ALP
351a
BADRAWY MRCP Revision

pancreatic cancer
351b
BADRAWY MRCP Revision

Wt loss, anemia
(macro/micro), no obvious
cause
352a
BADRAWY MRCP Revision

coeliac (diarrhea does NOT
have to be present)
352b
BADRAWY MRCP Revision

Hematuria, proteinuria,
best investigation
353a
BADRAWY MRCP Revision

if glomerulonephritis
suspected ➜ renal biopsy
353b
BADRAWY MRCP Revision

Venous ulcer treatment
354a
BADRAWY MRCP Revision

exclude arteriopathy (eg
ABPI), control edema,
prevent infection,
compression bandaging.
354b
BADRAWY MRCP Revision

Fever, lymphadenopathy,
lymphocytosis, pharygitis
355a
BADRAWY MRCP Revision

EBV ➜ heterophile
antibodies
355b
BADRAWY MRCP Revision

GI bleed after endovascular
AAA Surgery
356a
BADRAWY MRCP Revision

aortoenteric fistula
356b
BADRAWY MRCP Revision

Functional
hypogonadotrophic
hypogonadism
357a
BADRAWY MRCP Revision

amennorhea. LH and FSH
both low.
All other hormones are
usually normal. Ferritin
low.
357b
BADRAWY MRCP Revision

Vitiligo - commonest
assoctions
358a
BADRAWY MRCP Revision

pernicious anemia type 1
DM , autoimmune
addisons, autoimmune
thyoid
358b
BADRAWY MRCP Revision

Peripheral neuropathy
359a
BADRAWY MRCP Revision

a) B12 - rapid, dorsal columns (joint pos,
vibration), sensory
ataxia, pseudoathetosis of upperlimbs
b) diabetic - slow, s...

CNS abnormalities in HIV
360a
BADRAWY MRCP Revision

toxoplaasmosis (multiple ring
enhancing), lymphoma (solitary
lesion). HIV encephalopathy,
progressive multifocal
leucoence...

Travellers diarrohea
361a
BADRAWY MRCP Revision

chronic (>2 WEEKS) giardia
(incidious onset rx.
Metronidazole),
SALMONELLA (serious systemic
illness), E.coli (rx. Ciprofl...

If you see blood on
urinalysis forget about
362a
BADRAWY MRCP Revision

RAS
362b
BADRAWY MRCP Revision

Fasciculations
363a
BADRAWY MRCP Revision

Motor neurone diease
363b
BADRAWY MRCP Revision

Silvery white scale
364a
BADRAWY MRCP Revision

PSORIASIS
364b
BADRAWY MRCP Revision

Hypopigmented
365a
BADRAWY MRCP Revision

vitiligo/pityriasis versicolor
365b
BADRAWY MRCP Revision

Pretibial myxedema
366a
BADRAWY MRCP Revision

Graves
366b
BADRAWY MRCP Revision

R. Arthritis with nephritic
syndrome
367a
BADRAWY MRCP Revision

looks for amyloidosis, even
by rectal biopsy.
367b
BADRAWY MRCP Revision

Your valuable comments
are highly appreciated.
368a
BADRAWY MRCP Revision

Thank You
368b
BADRAWY MRCP Revision

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