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AI and Healthcare 2023.pdf

The document explores the intersection of artificial intelligence (AI) and healthcare, detailing the history of AI, its definitions, and the distinction between AI and machine learning. It highlights current applications of AI in healthcare, including patient monitoring, predictive analytics, and clinical trials, while also addressing barriers such as data bias and discrimination. Furthermore, the document discusses the future potential of AI in improving healthcare outcomes and efficiency.

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Artificial Intelligence & Healthcare Kimberley R. Barker, MLIS Librarian for Belonging & Community Engagement Health Sciences Library
Learning Objectives • Learn to define “Artificial Intelligence” • Learn about the history of AI • Learn the difference between AI and machine learning • Learn about AI industry leaders • Learn about popular current uses of machine learning in daily life • Learn about current healthcare applications for AI • Learn about barriers to AI • Learn about possible AI uses in the near future
AI: definition •“…the theory and development of computer systems able to perform tasks that normally require human intelligence, such as visual perception, speech recognition, decision- making, and translation between languages.”
AI: a brief history •An ancient idea •Talos & Galatea
AI: a brief history, 2 • 1206- Al-Jazari creates a programmable orchestra of mechanical human beings • 1580- Rabbai Judah Loew Ben Bezalel (allegedly) creates the Golem • 1642- Blaise Pascal invents the first digital calculating machine • 1726- Jonathon Swift publishes Gulliver’s Travels à the Engine:“a Project for improving speculative Knowledge by practical and mechanical Operations ”
AI: a brief history 3 • 1818- Mary Shelley publishes Frankenstein; or The Modern Prometheus- speculates on the ethics of creating life • 1863- Samuel Butler speculates that machines will one day become conscious and supplant humanity • 1941- Konrad Zuse builds first working program-controlled computer • 1945- Game theory is introduced in Theory of Games and Economic Behavior; integral to development of modern AI • 1950- Alan Turing introduces the idea of the Turing Test • 1950- Isaac Asimov publishes The Three Laws of Robotics
AI: a brief history 4 • 1951- first working AI programs written; checkers and chess • 1955- Arthur Samuels builds a program which learns how to play checkers • 1956- Dartmouth College Summer AI Conference organized (term “artificial intelligence” is coined) • 1959- Jonathon McCarthy and Marvin Minsky found the MIT AI Lab • Late 1950’s-early 1960’s- Margaret Masterson and colleagues design semantic nets for machine translation • 1960’s- Ray Solomonoff lays foundation of mathematical theory of AI
AI: a brief history, 5 • 1963- ANALOGY (written by Thomas Evans) demonstrates that computers can solve the same analogy questions that are given on IQ tests • 1965- ELIZA- interactive program that carries on a dialogue in English, on any topic • 1965- DENDRAI, 10-year effort to to deduce the molecular structure of organic compounds using scientific instrument data. First expert system • 1966- Ross Quillian demonstrates semantic nets • 1969- Shakey the Robot demonstrated animal locomotion, perception and problem-solving
AI: a brief history 6 • Early 1970’s- Jane Robinson establishes a Natural Language Processing Center • 1973- Assembly Robotics Group builds Freddy Robot; capable of using visual perception to locate and assemble models • 1975- Marvin Minsky publishes “Frames”; brings together ideas about schemas and semantic links • 1979-the Stanford Cart; first computer-controlled automated vehicle. Successfully navigated a room full of chairs • 1986- robot cars from the University of Munich drove up to 55 mph on empty streets
AI: a brief history 7 • 1986- Barbara Grosz and Candace Sidner create the first computation model of discourse, establishing the field of research. • 1997- Deep Blue chess machine defeats the (then) world chess champion, Garry Kasparov. • 1998- Furby released (first successful attempt at producing a type of A.I to reach domestic market) • 1998- Tim Berners-Lee publishes Semantic Web Road Map • Late 1990’s- Web crawlers and other AI-based information extraction programs become essential in widespread use of the Internet
AI: a brief history 8 • 2000- Nomad robot explores remote regions of Antarctica looking for meteorite samples • 2002- Roomba released (autonomous vacuum) • 2004- DARPA Grand Challenge (prize money for autonomous vehicles) • 2004- “Spirit” and “Opportunity” autonomously navigate Mars • 2005- Recommendation technology based on tracking web activity brings AI to marketing. • 2005- Blue Brain- project to simulate the brain at molecular detail • 2009- Google self-driving car
AI: a brief history 9 • 2010- Microsoft Kinect (machine learning for human motion capture) • 2011- Watson defeats Jeopardy! champions • 2011-2014- Siri, Google Now, Cortana (natural language; recommendations; perform actions) • 2013- NEIL (Never Ending Image Learner) released at Carnegie Mellon University; constantly compared and analyzed relationships between different images • 2015- Hawking, Musk, Wozniak and 3,000 researchers in AI and robotics sign open letter calling for ban on research of autonomous weapons
AI: a brief history 10 • 2017- Asilomar Conference on Beneficial AI; discussed AI ethics and strategies for bringing about beneficial AI while avoiding risk from artificial general intelligence. • 2018- • Google’s Duplex impressed a trade show audience with its human- sounding voice and ability to make calls on behalf of clients • Amazon’s Rekognition facial recognition software caused concern due to ethical concerns • Google’s Project Maven was a collaboration with the Department of Defense to allow the use of its API in drones
AI: a brief history, 11 • 2019 • FDNA uses AI to detect rare diseases • “Genomic insights through next-generation phenotyping (NGP)” • 2020 • OpenAI announced DALL-E • multimodal AI system that generates images from text • 2022 • Midjourney , an artificial intelligence art generation service, enters open beta • Chatgpt launched by OpenAI
Examples of AI-Generated Avatars These were created with different AI generators and needed between 8-20 pictures of me to generate the images.
According to pwc’s research, AI’s estimated potential contribution to the global economy by 2030 will be $15.7 trillion.
The Interactive Data Explorer from pwc: https://www.pwc.com/gx/en/i ssues/data-and- analytics/publications/artificial -intelligence- study.html#explorer
Neural Networks- crucial to development •“A Neural Network is a computer system designed to work by classifying information in the same way a human brain does. It can be taught to recognize, for example, images, and classify them according to elements they contain.”
Interpretation of a neural network
AI in (Old) Pop Culture • C-3PO • Skynet • Baymax • WOTAN (Doctor Who) • Omnius (Dune) • Cylons • Transformers • The Matrix
AI vs. Machine Learning • AI is the broad category; machine learning is one application of AI • “AI is basically the intelligence – how we make machines intelligent, while machine learning is the implementation of the computer methods that support it.” For examples, if the category was pasta, tortellini would be one type of pasta.
Machine Learning- definition • “Machine learning is an application of artificial intelligence (AI) that provides systems the ability to automatically learn and improve from experience without being explicitly programmed. Machine learning focuses on the development of computer programs that can access data and use it learn for themselves.” • *pattern recognition • ML is really “start of the art” of AI; true AI isn’t a reality yet
Examples of Machine Learning • Virtual Personal Assistants- Siri, Alexis, Cortana • Traffic predictions • Surveillance systems • Computer vision à how Pinterest knows which pins to recommend • Facial recognition • Chatbots- Chatgpt, FB, Replika, Dadbot • Shopping recommendations (Alibaba)
Examples of Machine Learning • Purchase predictions • Video games • Self-driving cars • Fraud detection • News generation • Pandora
AI Industry Leaders
Famous Real AI • Google Bard
Let’s talk about Chatgpt… • What is it? • Chat Generative Pre-Trained Transformer is a Large Language Model (LLM) machine learning chatbot, created by AINOW and released in November 2022 • Why all the excitement? • Chatgpt is the first chatbot of its kind to be able to write and CONVERSE convincingly in English. • How is it being used in the sciences? • Write essays & talks • Summarize literature • Improve papers • Identify research gaps • Write computer code • Perform statistical analyses
Chatgpt- on the positive side… • How might it revolutionize research practices? • Accelerate the innovation process • Shorten time-to-publication • Make science more equitable • Increase the diversity of science perspectives - From “ChatGPT: five priorities for research”
Chatgpt, on the negative side… • Gets things wrong, spurring misinformation- and it’s very convincing • Needs to be carefully monitored/edited by a human subject matter expert • Its writings lack depth • It lacks its own set of ethics, relying on the sources from whom it learns to “create” them
Chatgpt: an example from a friend: “write an incident report for an RA conducting rounds who identified a broken window”
Examples of AI start-ups • Zipline- blood & vaccine delivery via drones • Everlaw- trial preparation through document analysis • Voicera- personal assistant • ShieldAI- drones in combat situations (mapping, identification)
Why AI in healthcare? •Save time/efficiency •Shortage of clinicians •Improve patient outcomes
Why AI in healthcare now? •The perfect storm •Tons of data ("big data") generated by the minute •Robust algorithms •Processing power
Examples of AI in healthcare • Patient self-monitoring (builds on the “quantified self”) • Chronic and acute conditions; post-surgery • PeerWell- AI for total joint replacement • Patients begin using app before surgery. Patients receive customized daily lessons and tasks which require them to input their results directly into the app. Machine learning algorithm adjusts pre- and post-surgery instructions based on patient input. •Extended Visual Assistant (EVA) • Voice-controlled eyewear for the visually impaired • Uses machine learning to recognize objects, text, signs, etc, and verbally describes what it sees
AI & Healthcare • Patient self-monitoring, cont • AI apps for more common ailments • Diabetes management • Palliative care • Congenital heart disease • Clinical trials • Finding the right candidates for trials • Predicting bioactivity of patients in trials • Scheduling • TrueCare’s Baymax bot • Finds a doctor for you and then schedules an appointment
Examples of AI in Healthcare • Pattern recognition • Skin cancer detection • Arterys- AI assistant for radiologists (1st FDA approval) • Disease detection
How AI in Predictive Analytics/Modelling can benefit patients • Increase the accuracy of diagnoses • Improve preventive medicine and public health • Enhance personalized care • Accurately predict insurance costs • Streamline research and development with prediction models • Guide drug development to deliver medications that meet public need • Better patient outcomes
AI in Research •AIs can (and are!): • Analyze data • Clean data • Identify patterns in data • Discovery tools • Gather data; e.g.; drone operators in places that are too remote or dangerous for humans • Analyze & match data; e.g., matching patients to clinical trials
Barriers to use of AI in healthcare •Dirty data (data management has to happen first) •Silo’d data •Discrimination •Patients can’t be adequately served if discriminated against
Barriers to use of AI in healthcare •Lack of infrastructure/data management plan •DMP should be predicated on International Data Corporation (IDC) Third Platform Principles, which are anchored by 4 areas: •Big Data & Analytics •Cloud •Mobile •Social
AI and Discrimination • AI is only as unbiased as: • the people who program it (mostly men; mostly white, in the US) • the data on which its trained • Deep neural networks for images most often trained on ImageNet, which is heavily biased towards white Westerners • Natural language processing algorithms trained on data sets scraped from GoogleImages, GoogleNews, and Wikipedia- all heavily influenced by men, which have led to misogynistic AIs • “… Amazon’s computer models were trained to vet applicants by observing patterns in resumes submitted to the company over a 10-year period. Most came from men, a reflection of male dominance across the tech industry.” – Amazon scraps secret AI recruiting tool that showed bias against women (2018) • the systems & institutions into which AI is deployed
AI & Discrimination: Training Humans • “ first major photography exhibition devoted to training images: the collections of photos used by scientists to train artificial intelligence (AI) systems in how to ‘see’ and categorize the world.” • Explores two fundamental issues: • how humans are represented, interpreted and codified through training datasets • how technological systems harvest, label and use this material
AI & Discrimination: Training Humans • Also of interest to the creators: • Affect-training recognition, a system used by AI in security & hiring systems, etc, to determine a person’s mental & emotional “aims to detect and classify emotions by analyzing any face” • ATR based on the work of Paul Ekman • From his website: “Dr. Ekman identified the six basic emotions as anger, surprise, disgust, enjoyment, fear, and sadness. His research shows the strongest evidence to date of a seventh emotion, which is contempt.” • Ekman’s work is highly disputed by other researchers in both the same and different fields.
Affect- Training Recognition • Now ATR is being used in hiring, security, and other systems to determine whether someone would be a good employee or is a threat. • HireVu • “AI system to extract microexpressions, tone of voice, and other variables from video job interviews, which it used to compare job applicants against a company’s top performers.” • Emotient (Apple) • Claimed to be capable of identifying emotions from images of faces • Affectiva • detecting distracted and “risky” drivers on roads • measuring consumers’ emotional responses to advertising
AI & Discrimination • ImageNet Roulette- And, surprise(!), AI has some pretty racist and misogynistic ideas about people. Or, rather, the dataset ImageNet Roulette draws from, ImageNet, is filled with problematic categories that reflect the bias often inherent in the large datasets that make machine learning possible. • ”Automated systems that replicate, and by extension exacerbate, the biases present in society have the power to codify those very problems.”
Future applications of AI in healthcare • AI-powered predictive care • networked hospitals • better patient and staff experiences
Questions? Kimberley R Barker, MLIS krb3k@virginia.edu
Resources • Timeline of Artificial Intelligence https://en.wikipedia.org/wiki/Timeline_of_artificial_intelligence • History of Machine Learning https://www.estory.io/timeline/view/JlYn6L/445/History_of_Machine_Learning • “What Is The Difference Between Artificial Intelligence And Machine Learning?” https://bit.ly/2jHOxFA • Everlaw- trial prep via document analysis https://www.everlaw.com/ • Voicera- https://www.voicera.com/ • Extended Visual Assistant (EVA), AI assistant
Resources • “Neural Network | Human Brain versus computer” https://techbuf.com/human-brain-neural-network/ • ShieldAI- drones for combat situations https://www.shield.ai/ • Wordsmith- https://automatedinsights.com/wordsmith • AI’s role in healthcare starts small, gets bigger” https://bit.ly/2F93JZu • “How AI is transforming healthcare and solving problems in 2017” https://bit.ly/2qWvugp • “Google, Fitbit, startups storm into healthcare AI” https://bit.ly/2ryvJgn
Resources • “Artificial intelligence messenger bot, Baymax” https://www.medicaldesignandoutsourcing.com/artificial-intelligence-messenger-bot/ • “’Big Hero 6': The Science Behind Baymax, Disney's Big, Soft Robot” https://www.nbcnews.com/tech/gadgets/big-hero-6-science-behind-baymax-disneys-big- soft-robot-n240241 • “No, Facebook Did Not Panic and Shut Down an AI Program That Was Getting Dangerously Smart” https://gizmodo.com/no-facebook-did-not-panic-and-shut-down-an-ai-program- 1797414922 • “Google Self-Driving Cars Have Learned How to Interpret Cyclists' Hand Signals” http://fortune.com/2016/07/06/google-self-driving-cars-cyclist/ • AI Chatbots Are Getting Better. But an Interview With ChatGPT Reveals Their Limits- https://time.com/6238781/chatbot-chatgpt-ai-interview/
Resources • “Predictive analytics in health care using machine learning tools and techniques” https://ieeexplore.ieee.org/document/8250771/ • “How artificial intelligence is revolutionizing the patient experience in healthcare” https://www.telusinternational.com/articles/ai-patient-experience-healthcare/ • “'It Is Crazy!' The Promise and Potential Peril of ChatGPT” https://www.medpagetoday.com/opinion/patientcenteredmedicalhome/102557 • Creating Artificial Intelligence 'In Full Color’ https://www.nursing.virginia.edu/news/ai-ecosystem-williams-moorman/ • “These ER Docs Invented a Real Star Trek Tricorder” https://www.nbcnews.com/mach/technology/these-er-docs-invented-real-star-trek- tricorder-n755631 • “What Companies Are Winning The Race For Artificial Intelligence?” https://www.forbes.com/sites/quora/2017/02/24/what-companies-are-winning-the- race-for-artificial-intelligence/#34820637f5cd
Resources • “Just a Few of the Amazing Things AI Is Doing in Healthcare” https://singularityhub.com/2018/03/29/just-a-few-of-the-amazing-things-ai-is-doing-in- healthcare/#sm.00000ffrfb4hgpe2xxzxbtpckn6ws • “Artificial intelligence powers digital medicine” https://www.nature.com/articles/s41746-017-0012-2 • “Man against machine: AI is better than dermatologists at diagnosing skin cancer” https://www.eurekalert.org/pub_releases/2018-05/esfm-mam052418.php • "Contributed: Top 10 Use Cases for AI in Healthcare” https://www.mobihealthnews.com/news/contributed-top-10-use-cases-ai-healthcare • Can Artificial Intelligence detect Melanoma? https://www.mskcc.org/news/can-artificial-intelligence-detect-melanoma • Artificial intelligence in disease diagnosis: a systematic literature review, synthesizing framework and future research agenda- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754556/
Resources • What Do We Do About the Biases in AI?- https://hbr.org/2019/10/what-do-we- do-about-the-biases-in-ai • How tech's white male workforce feeds bias into AI- https://www.cbsnews.com/news/ai-bias-problem-techs-white-male-workforce/ • AI can be sexist and racist — it’s time to make it fair- https://www.nature.com/articles/d41586-018-05707-8 • Amazon scraps secret AI recruiting tool that showed bias against women- https://www.reuters.com/article/us-amazon-com-jobs-automation- insight/amazon-scraps-secret-ai-recruiting-tool-that-showed-bias-against- women-idUSKCN1MK08G •
Resources • AINOW 2019 Report- https://ainowinstitute.org/AI_Now_2019_Report.pdf • ChatGPT: five priorities for research- https://www.nature.com/articles/d41586-023- 00288-7 • Replika AI- https://replika.com/ • Project December- https://projectdecember.net/ • Hereafter AI- https://www.hereafter.ai/ • Good Bot, Bad Bot | Part III: Life, death and AI- Endless Thread podcast- https://www.wbur.org/endlessthread/2022/11/18/life-death-ai • Good Bot, Bad Bot | Part I: Mental Health and Bot Therapy- Endless Thread podcast- https://www.wbur.org/endlessthread/2022/11/04/bots-mental-health • Whispers of AI’s Modular Future- https://www.newyorker.com/tech/annals-of- technology/whispers-of-ais-modular-future
Resources • Arterys Resources https://www.arterys.com/resources-library • “The future is now? Zipline http://www.flyzipline.com/ • “Zipline, which delivers lifesaving medical supplies by drone, now valued at $1.2 billion” https://www.cnbc.com/2019/05/17/zipline-medical-delivery-drone-start-up-now-valued-at- 1point2-billion.html • AITopics https://aitopics.org/search • Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge https://jamanetwork.com/journals/jama/fullarticle/2801170 • Peer-Reviewed Journal Publishes Paper Written Almost Entirely by ChatGPT https://www.medpagetoday.com/special-reports/exclusives/102960? • Worldwide Artificial Intelligence Spending Guide- https://www.idc.com/getdoc.jsp?containerId=IDC_P33198
Resources • Google Bard AI hands-on: A work in progress with plenty of caveats- https://www.engadget.com/google-bard-ai-hands-on-a-work-in-progress-with-plenty-of- caveats-170956025.html • Microsoft Adds DALL-E AI Image Generator to Bing- https://gizmodo.com/microsoft-adds- dall-e-ai-image-generator-to-bing-1850247593 • Microsoft's new AI chatbot has been saying some 'crazy and unhinged things’- https://www.npr.org/2023/03/02/1159895892/ai-microsoft-bing-chatbot • See what AI really thinks of you with this deeply humbling website- https://mashable.com/article/ai-machine-learning-imagenet-roulette
Resources • Artificial Intelligence is Misreading Human Emotion- https://www.theatlantic.com/technology/archive/2021/04/artificial-intelligence-misreading- human-emotion/618696/ • Global Emotion Detection & Recognition Market Size is Projected to Grow from USD 21.6 Billion in 2019 to USD 56.0 Billion by 2024, at a CAGR of 21.0% - ResearchAndMarkets.com- https://www.businesswire.com/news/home/20200213005614/en/Global-Emotion-Detection- Recognition-Market-Size-is-Projected-to-Grow-from-USD-21.6-Billion-in-2019-to-USD-56.0- Billion-by-2024-at-a-CAGR-of-21.0---ResearchAndMarkets.com • World Economic Forum: 3 ways AI will transform healthcare in the next decade- https://www.beckershospitalreview.com/innovation/world-economic-forum-3-ways-ai-will- transform-healthcare-in-the-next-decade?oly_enc_id=6411D3520189C0K