SlideShare a Scribd company logo

Antimicrobials 1 Lec

•Download as PPT, PDF•
•
M
MD Specialclass
TechnologyBusiness
1 of 109
BETA LACTAM & OTHER CELL WALL- & MEMBRANE ACTIVE ANTIBIOTICS MA. LENY ALDA G. JUSAYAN, MD DEPARTMENT OF PHARMACOLOGY
Introduction ,[object Object]
History ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Chemical Properties of Penicillins ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Chemical Properties of Penicillins ,[object Object],[object Object],[object Object]
 
 
thiazolidine ring (A) connected to a b-lactam ring (B), to which is attached a side chain (R).
[object Object],[object Object]
Cell Wall production ,[object Object],[object Object],[object Object]
[object Object]
[object Object],[object Object],[object Object]
[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
 
 
 
Beta Lactam Antibiotics & Other Cell Wall Synthesis Inhibitors ,[object Object],[object Object],[object Object],[object Object],[object Object]
Classification ,[object Object],[object Object],[object Object]
PENICILLINS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PENICILLINS ,[object Object],[object Object],[object Object],[object Object]
Penicillinase Susceptible ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Penicillinase Susceptible ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Penicillinase Susceptible ,[object Object],[object Object],[object Object]
Mechanisms of Action: ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Mechanisms of Drug Actions by Enzyme Inhibition: ,[object Object]
:Mechanisms of Resistance: ,[object Object],[object Object],[object Object],[object Object]
 
Resistance to β-Lactams – Gram pos.
PHARMACOKINETICS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object]
Parenteral Administration of Penicillin G ,[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
PHARMACOKINETICS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADVERSE EFFECTS: ,[object Object],[object Object],[object Object],[object Object]
ADVERSE EFFECTS: ,[object Object],[object Object],[object Object],[object Object]
Specific toxicities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Specific toxicities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Unitage of Penicillin ,[object Object],[object Object],[object Object]
Penicillin G ,[object Object],[object Object]
Penicillin G ,[object Object],[object Object],[object Object]
B. Procaine Penicillin G – IM ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
D. Penicillin V ,[object Object],[object Object],[object Object],[object Object],[object Object]
E. Ampicillin and Amoxicillin ,[object Object],[object Object],[object Object],[object Object]
E. Ampicillin and Amoxicillin ,[object Object],[object Object],[object Object],[object Object],[object Object]
Ampicillin doses: ,[object Object],[object Object],[object Object],[object Object]
F. ESTERS OF AMPICILLIN ,[object Object],[object Object]
G. CARBOXYPENICILLINS and UREIDOPENICILLINS ,[object Object],[object Object],[object Object],[object Object],[object Object]
H. PENICILLINASE RESISTANT ,[object Object],[object Object],[object Object],[object Object]
H. PENICILLINASE RESISTANT ,[object Object],[object Object],[object Object],[object Object]
Drug-drug Interactions ,[object Object],[object Object]
Classification of the Penicillins and Summary of Their Pharmacological Properties ,[object Object]
[object Object]
[object Object]
Cephalosporins   First Generation        Second Generation     Third Generation       Fourth Generation                      * Oral Agent Cefadroxil *   Cefaclor * Cefdinir Cefepime   Cefazolin    Cefamandole  Cefoperaxone    Cefpirome   Cefelixin *   Cefonicid  Cefotaxime     Cephalothin    Ceforanide Ceftazidime     Cephaprin    Cefotetan Ceftibuten     Cephradine *   Cefoxitin  Ceftizoxime       Cefuroxime moxalactam Ceftriaxone
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cephalosporins ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
GENERAL PROPERTIES OF CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
GENERAL PROPERTIES OF CEPHALOSPORINS ,[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object]
THIRD GENERATION ,[object Object],[object Object],[object Object]
THIRD GENERATION ,[object Object],[object Object],[object Object],[object Object]
THIRD GENERATION ,[object Object],[object Object],[object Object],[object Object]
THIRD GENERATION ,[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object]
CEPHALOSPORINS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADVERSE EFFECTS of Cephalosporins ,[object Object],[object Object],[object Object],[object Object]
ADVERSE EFFECTS of Cephalosporins ,[object Object],[object Object],[object Object]
MONOBACTAMS ,[object Object],[object Object],[object Object]
Monobactam ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object]
MONOBACTAMS ,[object Object],[object Object]
BETA LACTAMASE INHIBITORS ,[object Object],[object Object],[object Object]
BETA LACTAMASE INHIBITORS ,[object Object],[object Object],[object Object],[object Object]
Carbapenems ,[object Object],[object Object],[object Object],[object Object]
Imipenem: ,[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Meropenem ,[object Object],[object Object],[object Object]
CARBAPENEMS ,[object Object],[object Object],[object Object],[object Object]
CARBAPENEMS ,[object Object],[object Object],[object Object],[object Object],[object Object]
A. VANCOMYCIN ,[object Object],[object Object],[object Object]
A. VANCOMYCIN ,[object Object],[object Object],[object Object]
A. VANCOMYCIN ,[object Object],[object Object],[object Object],[object Object]
B. FOSFOMYCIN ,[object Object],[object Object]
B. FOSFOMYCIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
C. BACITRACIN ,[object Object],[object Object],[object Object],[object Object],[object Object]
D. CYCLOSERINE ,[object Object],[object Object],[object Object],[object Object]
 
POST-TEST ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]

Recommended

Cell wall inhibitors
Cell wall inhibitorsCell wall inhibitors
Cell wall inhibitorsArtina Aquitania
 
Cell Wall Inhibitors
Cell Wall InhibitorsCell Wall Inhibitors
Cell Wall Inhibitorsshabeel pn
 
Pharmacology - Cell wall inhibitors 1
Pharmacology - Cell wall inhibitors 1Pharmacology - Cell wall inhibitors 1
Pharmacology - Cell wall inhibitors 1Areej Abu Hanieh
 
Cell wall inhibitors
Cell wall inhibitors Cell wall inhibitors
Cell wall inhibitors Rawan Adnan
 
Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!
Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!
Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!RxVichuZ
 
Beta lactam Antibiotics
Beta lactam AntibioticsBeta lactam Antibiotics
Beta lactam AntibioticsShefali Jaiswal
 
Antibiotics
AntibioticsAntibiotics
AntibioticsAMIR HASSAN
 
Antibiotics and Synthetic Antimicrobial agents
Antibiotics and Synthetic Antimicrobial agentsAntibiotics and Synthetic Antimicrobial agents
Antibiotics and Synthetic Antimicrobial agentsRinaldo John
 

Recommended

Cell wall inhibitors
Cell wall inhibitorsCell wall inhibitors
Cell wall inhibitorsArtina Aquitania
 
Cell Wall Inhibitors
Cell Wall InhibitorsCell Wall Inhibitors
Cell Wall Inhibitorsshabeel pn
 
Pharmacology - Cell wall inhibitors 1
Pharmacology - Cell wall inhibitors 1Pharmacology - Cell wall inhibitors 1
Pharmacology - Cell wall inhibitors 1Areej Abu Hanieh
 
Cell wall inhibitors
Cell wall inhibitors Cell wall inhibitors
Cell wall inhibitors Rawan Adnan
 
Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!
Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!
Antibiotics inhibiting cell wall synthesis- All you need to know, by RxVichuZ!RxVichuZ
 
Beta lactam Antibiotics
Beta lactam AntibioticsBeta lactam Antibiotics
Beta lactam AntibioticsShefali Jaiswal
 
Antibiotics
AntibioticsAntibiotics
AntibioticsAMIR HASSAN
 
Antibiotics and Synthetic Antimicrobial agents
Antibiotics and Synthetic Antimicrobial agentsAntibiotics and Synthetic Antimicrobial agents
Antibiotics and Synthetic Antimicrobial agentsRinaldo John
 
Fundamentals antimicrobial agents
Fundamentals antimicrobial agentsFundamentals antimicrobial agents
Fundamentals antimicrobial agentsraj kumar
 
2.ANTIBIOTIC (CELL WALL INHIBITORS)
2.ANTIBIOTIC (CELL WALL INHIBITORS)2.ANTIBIOTIC (CELL WALL INHIBITORS)
2.ANTIBIOTIC (CELL WALL INHIBITORS)Saminathan Kayarohanam
 
Antibiotic Mechanisms of Action
Antibiotic Mechanisms of ActionAntibiotic Mechanisms of Action
Antibiotic Mechanisms of ActionYazan Kherallah
 
Antibiotics- sail through
Antibiotics- sail throughAntibiotics- sail through
Antibiotics- sail throughLucas Ampaire
 
Antibacterials affecting cell membrane 03-05-2018
Antibacterials affecting cell membrane 03-05-2018Antibacterials affecting cell membrane 03-05-2018
Antibacterials affecting cell membrane 03-05-2018Ravi Kant Agrawal
 
Antibiotics & mechanisms of actions
Antibiotics & mechanisms of actionsAntibiotics & mechanisms of actions
Antibiotics & mechanisms of actionsabiola adeosun
 
Basics of Antimicrobial Drugs
Basics of Antimicrobial DrugsBasics of Antimicrobial Drugs
Basics of Antimicrobial DrugsASSOCHAM
 
Antibiotics
AntibioticsAntibiotics
AntibioticsSiniRajeesh
 
Antibiotics,,classification
Antibiotics,,classificationAntibiotics,,classification
Antibiotics,,classificationsumel ashique
 
Antibiotics
AntibioticsAntibiotics
AntibioticsKamma Madhavi
 
Chapter 6 inhibitors of cell wall synthesis
Chapter 6 inhibitors of cell wall synthesisChapter 6 inhibitors of cell wall synthesis
Chapter 6 inhibitors of cell wall synthesisAlia Najiha
 
Medicinal chemistry-beta lactam antibiotics
Medicinal chemistry-beta lactam antibioticsMedicinal chemistry-beta lactam antibiotics
Medicinal chemistry-beta lactam antibioticsDHARMENDRA BARIA
 
Antibiotics and its mechanism of action
Antibiotics and its mechanism of actionAntibiotics and its mechanism of action
Antibiotics and its mechanism of actionKarthik Rajendran
 
Cephalosporins & other β lactam antibiotics & cell wall destructors
Cephalosporins & other β lactam antibiotics & cell wall destructorsCephalosporins & other β lactam antibiotics & cell wall destructors
Cephalosporins & other β lactam antibiotics & cell wall destructorsFarazaJaved
 
Chemotherapy
ChemotherapyChemotherapy
ChemotherapyCh. Bhargava krishna
 
Beta lactam antibiotics
Beta lactam antibioticsBeta lactam antibiotics
Beta lactam antibioticsEneutron
 
Cephalosporins antibiotics - Beta lactam antibiotics
Cephalosporins antibiotics - Beta lactam antibioticsCephalosporins antibiotics - Beta lactam antibiotics
Cephalosporins antibiotics - Beta lactam antibioticsAkhil Nagar
 
Antimicrobial agents 2 wafaa
Antimicrobial agents 2 wafaaAntimicrobial agents 2 wafaa
Antimicrobial agents 2 wafaawafaa ahmed
 
MECHANISMS OF ANTIBACTERIAL ACTION.
MECHANISMS OF ANTIBACTERIAL ACTION.MECHANISMS OF ANTIBACTERIAL ACTION.
MECHANISMS OF ANTIBACTERIAL ACTION.Dr. Ravi Sankar
 
Mechanism of action of antibiotics
Mechanism of action of antibioticsMechanism of action of antibiotics
Mechanism of action of antibioticsMumtaz Ali
 
antibioticsmechanismsofactions-150428084652-conversion-gate02.pdf
antibioticsmechanismsofactions-150428084652-conversion-gate02.pdfantibioticsmechanismsofactions-150428084652-conversion-gate02.pdf
antibioticsmechanismsofactions-150428084652-conversion-gate02.pdfBucky10
 
_beta-lactam antibiotics M pharmacy Pharmacology
_beta-lactam antibiotics M pharmacy Pharmacology_beta-lactam antibiotics M pharmacy Pharmacology
_beta-lactam antibiotics M pharmacy PharmacologyAyodhya Paradhe
 

More Related Content

What's hot

Fundamentals antimicrobial agents
Fundamentals antimicrobial agentsFundamentals antimicrobial agents
Fundamentals antimicrobial agentsraj kumar
 
Antibiotic Mechanisms of Action
Antibiotic Mechanisms of ActionAntibiotic Mechanisms of Action
Antibiotic Mechanisms of ActionYazan Kherallah
 
Antibiotics- sail through
Antibiotics- sail throughAntibiotics- sail through
Antibiotics- sail throughLucas Ampaire
 
Antibacterials affecting cell membrane 03-05-2018
Antibacterials affecting cell membrane 03-05-2018Antibacterials affecting cell membrane 03-05-2018
Antibacterials affecting cell membrane 03-05-2018Ravi Kant Agrawal
 
Antibiotics & mechanisms of actions
Antibiotics & mechanisms of actionsAntibiotics & mechanisms of actions
Antibiotics & mechanisms of actionsabiola adeosun
 
Basics of Antimicrobial Drugs
Basics of Antimicrobial DrugsBasics of Antimicrobial Drugs
Basics of Antimicrobial DrugsASSOCHAM
 
Antibiotics,,classification
Antibiotics,,classificationAntibiotics,,classification
Antibiotics,,classificationsumel ashique
 
Chapter 6 inhibitors of cell wall synthesis
Chapter 6 inhibitors of cell wall synthesisChapter 6 inhibitors of cell wall synthesis
Chapter 6 inhibitors of cell wall synthesisAlia Najiha
 
Medicinal chemistry-beta lactam antibiotics
Medicinal chemistry-beta lactam antibioticsMedicinal chemistry-beta lactam antibiotics
Medicinal chemistry-beta lactam antibioticsDHARMENDRA BARIA
 
Antibiotics and its mechanism of action
Antibiotics and its mechanism of actionAntibiotics and its mechanism of action
Antibiotics and its mechanism of actionKarthik Rajendran
 
Cephalosporins & other β lactam antibiotics & cell wall destructors
Cephalosporins & other β lactam antibiotics & cell wall destructorsCephalosporins & other β lactam antibiotics & cell wall destructors
Cephalosporins & other β lactam antibiotics & cell wall destructorsFarazaJaved
 
Beta lactam antibiotics
Beta lactam antibioticsBeta lactam antibiotics
Beta lactam antibioticsEneutron
 
Cephalosporins antibiotics - Beta lactam antibiotics
Cephalosporins antibiotics - Beta lactam antibioticsCephalosporins antibiotics - Beta lactam antibiotics
Cephalosporins antibiotics - Beta lactam antibioticsAkhil Nagar
 
Antimicrobial agents 2 wafaa
Antimicrobial agents 2 wafaaAntimicrobial agents 2 wafaa
Antimicrobial agents 2 wafaawafaa ahmed
 
MECHANISMS OF ANTIBACTERIAL ACTION.
MECHANISMS OF ANTIBACTERIAL ACTION.MECHANISMS OF ANTIBACTERIAL ACTION.
MECHANISMS OF ANTIBACTERIAL ACTION.Dr. Ravi Sankar
 
Mechanism of action of antibiotics
Mechanism of action of antibioticsMechanism of action of antibiotics
Mechanism of action of antibioticsMumtaz Ali
 

What's hot (20)

Fundamentals antimicrobial agents
Fundamentals antimicrobial agentsFundamentals antimicrobial agents
Fundamentals antimicrobial agents
 
2.ANTIBIOTIC (CELL WALL INHIBITORS)
2.ANTIBIOTIC (CELL WALL INHIBITORS)2.ANTIBIOTIC (CELL WALL INHIBITORS)
2.ANTIBIOTIC (CELL WALL INHIBITORS)
 
Antibiotic Mechanisms of Action
Antibiotic Mechanisms of ActionAntibiotic Mechanisms of Action
Antibiotic Mechanisms of Action
 
Antibiotics- sail through
Antibiotics- sail throughAntibiotics- sail through
Antibiotics- sail through
 
Antibacterials affecting cell membrane 03-05-2018
Antibacterials affecting cell membrane 03-05-2018Antibacterials affecting cell membrane 03-05-2018
Antibacterials affecting cell membrane 03-05-2018
 
Antibiotics & mechanisms of actions
Antibiotics & mechanisms of actionsAntibiotics & mechanisms of actions
Antibiotics & mechanisms of actions
 
Basics of Antimicrobial Drugs
Basics of Antimicrobial DrugsBasics of Antimicrobial Drugs
Basics of Antimicrobial Drugs
 
Antibiotics
AntibioticsAntibiotics
Antibiotics
 
Antibiotics,,classification
Antibiotics,,classificationAntibiotics,,classification
Antibiotics,,classification
 
Antibiotics
AntibioticsAntibiotics
Antibiotics
 
Chapter 6 inhibitors of cell wall synthesis
Chapter 6 inhibitors of cell wall synthesisChapter 6 inhibitors of cell wall synthesis
Chapter 6 inhibitors of cell wall synthesis
 
Medicinal chemistry-beta lactam antibiotics
Medicinal chemistry-beta lactam antibioticsMedicinal chemistry-beta lactam antibiotics
Medicinal chemistry-beta lactam antibiotics
 
Antibiotics and its mechanism of action
Antibiotics and its mechanism of actionAntibiotics and its mechanism of action
Antibiotics and its mechanism of action
 
Cephalosporins & other β lactam antibiotics & cell wall destructors
Cephalosporins & other β lactam antibiotics & cell wall destructorsCephalosporins & other β lactam antibiotics & cell wall destructors
Cephalosporins & other β lactam antibiotics & cell wall destructors
 
Chemotherapy
ChemotherapyChemotherapy
Chemotherapy
 
Beta lactam antibiotics
Beta lactam antibioticsBeta lactam antibiotics
Beta lactam antibiotics
 
Cephalosporins antibiotics - Beta lactam antibiotics
Cephalosporins antibiotics - Beta lactam antibioticsCephalosporins antibiotics - Beta lactam antibiotics
Cephalosporins antibiotics - Beta lactam antibiotics
 
Antimicrobial agents 2 wafaa
Antimicrobial agents 2 wafaaAntimicrobial agents 2 wafaa
Antimicrobial agents 2 wafaa
 
MECHANISMS OF ANTIBACTERIAL ACTION.
MECHANISMS OF ANTIBACTERIAL ACTION.MECHANISMS OF ANTIBACTERIAL ACTION.
MECHANISMS OF ANTIBACTERIAL ACTION.
 
Mechanism of action of antibiotics
Mechanism of action of antibioticsMechanism of action of antibiotics
Mechanism of action of antibiotics
 

Similar to Antimicrobials 1 Lec

antibioticsmechanismsofactions-150428084652-conversion-gate02.pdf
antibioticsmechanismsofactions-150428084652-conversion-gate02.pdfantibioticsmechanismsofactions-150428084652-conversion-gate02.pdf
antibioticsmechanismsofactions-150428084652-conversion-gate02.pdfBucky10
 
_beta-lactam antibiotics M pharmacy Pharmacology
_beta-lactam antibiotics M pharmacy Pharmacology_beta-lactam antibiotics M pharmacy Pharmacology
_beta-lactam antibiotics M pharmacy PharmacologyAyodhya Paradhe
 
Penicillins and Cephalosporins.ppt
Penicillins and Cephalosporins.pptPenicillins and Cephalosporins.ppt
Penicillins and Cephalosporins.pptssuser504dda
 
Lecture 7 micro-antibiotics-mbbs
Lecture 7 micro-antibiotics-mbbsLecture 7 micro-antibiotics-mbbs
Lecture 7 micro-antibiotics-mbbsMBBS IMS MSU
 
Mode of action of penicillin
Mode of action of penicillin Mode of action of penicillin
Mode of action of penicillin ShubhamDubey217
 
beta lactam antibiotics
beta lactam antibioticsbeta lactam antibiotics
beta lactam antibioticsRavish Yadav
 
Microbiology antibiotic
Microbiology antibioticMicrobiology antibiotic
Microbiology antibioticMBBS IMS MSU
 
Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...
Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...
Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...ANUSHA SHAJI
 
beta-lactam antibiotics pharmaceutical chemistry.pptx
beta-lactam antibiotics pharmaceutical chemistry.pptxbeta-lactam antibiotics pharmaceutical chemistry.pptx
beta-lactam antibiotics pharmaceutical chemistry.pptxmisgana18
 
Penicillins (ANTIBIOTICS)
Penicillins (ANTIBIOTICS)Penicillins (ANTIBIOTICS)
Penicillins (ANTIBIOTICS)Muhammad Arsal
 

Similar to Antimicrobials 1 Lec (20)

antibioticsmechanismsofactions-150428084652-conversion-gate02.pdf
antibioticsmechanismsofactions-150428084652-conversion-gate02.pdfantibioticsmechanismsofactions-150428084652-conversion-gate02.pdf
antibioticsmechanismsofactions-150428084652-conversion-gate02.pdf
 
_beta-lactam antibiotics M pharmacy Pharmacology
_beta-lactam antibiotics M pharmacy Pharmacology_beta-lactam antibiotics M pharmacy Pharmacology
_beta-lactam antibiotics M pharmacy Pharmacology
 
PBP2a
PBP2aPBP2a
PBP2a
 
Penicillin's
Penicillin'sPenicillin's
Penicillin's
 
Penicillin
PenicillinPenicillin
Penicillin
 
Penicillins and Cephalosporins.ppt
Penicillins and Cephalosporins.pptPenicillins and Cephalosporins.ppt
Penicillins and Cephalosporins.ppt
 
Antibiotics
AntibioticsAntibiotics
Antibiotics
 
Antibiotics
AntibioticsAntibiotics
Antibiotics
 
Cell wall.pptx
Cell wall.pptxCell wall.pptx
Cell wall.pptx
 
Penicillins (VK)
Penicillins (VK)Penicillins (VK)
Penicillins (VK)
 
Lecture 7 micro-antibiotics-mbbs
Lecture 7 micro-antibiotics-mbbsLecture 7 micro-antibiotics-mbbs
Lecture 7 micro-antibiotics-mbbs
 
Mode of action of penicillin
Mode of action of penicillin Mode of action of penicillin
Mode of action of penicillin
 
beta lactam antibiotics
beta lactam antibioticsbeta lactam antibiotics
beta lactam antibiotics
 
Antibiotics
AntibioticsAntibiotics
Antibiotics
 
Antibiotic Penicillin
Antibiotic PenicillinAntibiotic Penicillin
Antibiotic Penicillin
 
Microbiology antibiotic
Microbiology antibioticMicrobiology antibiotic
Microbiology antibiotic
 
Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...
Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...
Penicillins- Mechanism of action, Antimicrobial spectrum & Antibacterial resi...
 
beta-lactam antibiotics pharmaceutical chemistry.pptx
beta-lactam antibiotics pharmaceutical chemistry.pptxbeta-lactam antibiotics pharmaceutical chemistry.pptx
beta-lactam antibiotics pharmaceutical chemistry.pptx
 
Penicillins (ANTIBIOTICS)
Penicillins (ANTIBIOTICS)Penicillins (ANTIBIOTICS)
Penicillins (ANTIBIOTICS)
 
cephalo.ppt
cephalo.pptcephalo.ppt
cephalo.ppt
 

More from MD Specialclass

Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...
Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...
Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...MD Specialclass
 
Git diseases presentn no. 2 applied nutrition
Git diseases presentn no. 2 applied nutritionGit diseases presentn no. 2 applied nutrition
Git diseases presentn no. 2 applied nutritionMD Specialclass
 
Getting ahead of headaches
Getting ahead of headachesGetting ahead of headaches
Getting ahead of headachesMD Specialclass
 
EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL MD Specialclass
 
EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL MD Specialclass
 
Hepatocellular carcinoma
Hepatocellular carcinomaHepatocellular carcinoma
Hepatocellular carcinomaMD Specialclass
 
Normal sleep and sleep disorders
Normal sleep and sleep disordersNormal sleep and sleep disorders
Normal sleep and sleep disordersMD Specialclass
 
Toxic and drug induced hepatitis
Toxic and drug induced hepatitisToxic and drug induced hepatitis
Toxic and drug induced hepatitisMD Specialclass
 
Complications of cirrhosis
Complications of cirrhosisComplications of cirrhosis
Complications of cirrhosisMD Specialclass
 

More from MD Specialclass (20)

Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...
Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...
Applied nutrition 3 rd presentation - diseases of liver, gall bladder, and ...
 
Git diseases presentn no. 2 applied nutrition
Git diseases presentn no. 2 applied nutritionGit diseases presentn no. 2 applied nutrition
Git diseases presentn no. 2 applied nutrition
 
Getting ahead of headaches
Getting ahead of headachesGetting ahead of headaches
Getting ahead of headaches
 
Acute brain attack 911
Acute brain attack 911Acute brain attack 911
Acute brain attack 911
 
Hema intro anemia
Hema intro anemiaHema intro anemia
Hema intro anemia
 
EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL
 
EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL EXCRETA, SEWAGE, REFUSE DISPOSAL
EXCRETA, SEWAGE, REFUSE DISPOSAL
 
Fever & id diet final
Fever & id diet finalFever & id diet final
Fever & id diet final
 
Eating disorders
Eating disordersEating disorders
Eating disorders
 
Hepatocellular carcinoma
Hepatocellular carcinomaHepatocellular carcinoma
Hepatocellular carcinoma
 
Eating disorders
Eating disordersEating disorders
Eating disorders
 
Normal sleep and sleep disorders
Normal sleep and sleep disordersNormal sleep and sleep disorders
Normal sleep and sleep disorders
 
Tic disorder
Tic disorderTic disorder
Tic disorder
 
Thyroid
ThyroidThyroid
Thyroid
 
Dermatology dr.n.ramos
Dermatology dr.n.ramosDermatology dr.n.ramos
Dermatology dr.n.ramos
 
Tic disorder
Tic disorderTic disorder
Tic disorder
 
Toxic and drug induced hepatitis
Toxic and drug induced hepatitisToxic and drug induced hepatitis
Toxic and drug induced hepatitis
 
Pancreatic disease
Pancreatic diseasePancreatic disease
Pancreatic disease
 
Liver disease
Liver diseaseLiver disease
Liver disease
 
Complications of cirrhosis
Complications of cirrhosisComplications of cirrhosis
Complications of cirrhosis
 

Recently uploaded

Digital Identity is Under Attack: FIDO Paris Seminar.pptx
Digital Identity is Under Attack: FIDO Paris Seminar.pptxDigital Identity is Under Attack: FIDO Paris Seminar.pptx
Digital Identity is Under Attack: FIDO Paris Seminar.pptxLoriGlavin3
 
unit 4 immunoblotting technique complete.pptx
unit 4 immunoblotting technique complete.pptxunit 4 immunoblotting technique complete.pptx
unit 4 immunoblotting technique complete.pptxBkGupta21
 
Use of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptx
Use of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptxUse of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptx
Use of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptxLoriGlavin3
 
Ensuring Technical Readiness For Copilot in Microsoft 365
Ensuring Technical Readiness For Copilot in Microsoft 365Ensuring Technical Readiness For Copilot in Microsoft 365
Ensuring Technical Readiness For Copilot in Microsoft 3652toLead Limited
 
Moving Beyond Passwords: FIDO Paris Seminar.pdf
Moving Beyond Passwords: FIDO Paris Seminar.pdfMoving Beyond Passwords: FIDO Paris Seminar.pdf
Moving Beyond Passwords: FIDO Paris Seminar.pdfLoriGlavin3
 
New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024
New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024
New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024BookNet Canada
 
DevoxxFR 2024 Reproducible Builds with Apache Maven
DevoxxFR 2024 Reproducible Builds with Apache MavenDevoxxFR 2024 Reproducible Builds with Apache Maven
DevoxxFR 2024 Reproducible Builds with Apache MavenHervé Boutemy
 
Hyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdf
Hyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdfHyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdf
Hyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdfPrecisely
 
The Ultimate Guide to Choosing WordPress Pros and Cons
The Ultimate Guide to Choosing WordPress Pros and ConsThe Ultimate Guide to Choosing WordPress Pros and Cons
The Ultimate Guide to Choosing WordPress Pros and ConsPixlogix Infotech
 
Passkey Providers and Enabling Portability: FIDO Paris Seminar.pptx
Passkey Providers and Enabling Portability: FIDO Paris Seminar.pptxPasskey Providers and Enabling Portability: FIDO Paris Seminar.pptx
Passkey Providers and Enabling Portability: FIDO Paris Seminar.pptxLoriGlavin3
 
Are Multi-Cloud and Serverless Good or Bad?
Are Multi-Cloud and Serverless Good or Bad?Are Multi-Cloud and Serverless Good or Bad?
Are Multi-Cloud and Serverless Good or Bad?Mattias Andersson
 
SIP trunking in Janus @ Kamailio World 2024
SIP trunking in Janus @ Kamailio World 2024SIP trunking in Janus @ Kamailio World 2024
SIP trunking in Janus @ Kamailio World 2024Lorenzo Miniero
 
The Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptx
The Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptxThe Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptx
The Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptxLoriGlavin3
 
DSPy a system for AI to Write Prompts and Do Fine Tuning
DSPy a system for AI to Write Prompts and Do Fine TuningDSPy a system for AI to Write Prompts and Do Fine Tuning
DSPy a system for AI to Write Prompts and Do Fine TuningLars Bell
 
Merck Moving Beyond Passwords: FIDO Paris Seminar.pptx
Merck Moving Beyond Passwords: FIDO Paris Seminar.pptxMerck Moving Beyond Passwords: FIDO Paris Seminar.pptx
Merck Moving Beyond Passwords: FIDO Paris Seminar.pptxLoriGlavin3
 
Advanced Computer Architecture – An Introduction
Advanced Computer Architecture – An IntroductionAdvanced Computer Architecture – An Introduction
Advanced Computer Architecture – An IntroductionDilum Bandara
 
Developer Data Modeling Mistakes: From Postgres to NoSQL
Developer Data Modeling Mistakes: From Postgres to NoSQLDeveloper Data Modeling Mistakes: From Postgres to NoSQL
Developer Data Modeling Mistakes: From Postgres to NoSQLScyllaDB
 
Scanning the Internet for External Cloud Exposures via SSL Certs
Scanning the Internet for External Cloud Exposures via SSL CertsScanning the Internet for External Cloud Exposures via SSL Certs
Scanning the Internet for External Cloud Exposures via SSL CertsRizwan Syed
 
WordPress Websites for Engineers: Elevate Your Brand
WordPress Websites for Engineers: Elevate Your BrandWordPress Websites for Engineers: Elevate Your Brand
WordPress Websites for Engineers: Elevate Your Brandgvaughan
 

Recently uploaded (20)

Digital Identity is Under Attack: FIDO Paris Seminar.pptx
Digital Identity is Under Attack: FIDO Paris Seminar.pptxDigital Identity is Under Attack: FIDO Paris Seminar.pptx
Digital Identity is Under Attack: FIDO Paris Seminar.pptx
 
unit 4 immunoblotting technique complete.pptx
unit 4 immunoblotting technique complete.pptxunit 4 immunoblotting technique complete.pptx
unit 4 immunoblotting technique complete.pptx
 
Use of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptx
Use of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptxUse of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptx
Use of FIDO in the Payments and Identity Landscape: FIDO Paris Seminar.pptx
 
Ensuring Technical Readiness For Copilot in Microsoft 365
Ensuring Technical Readiness For Copilot in Microsoft 365Ensuring Technical Readiness For Copilot in Microsoft 365
Ensuring Technical Readiness For Copilot in Microsoft 365
 
Moving Beyond Passwords: FIDO Paris Seminar.pdf
Moving Beyond Passwords: FIDO Paris Seminar.pdfMoving Beyond Passwords: FIDO Paris Seminar.pdf
Moving Beyond Passwords: FIDO Paris Seminar.pdf
 
New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024
New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024
New from BookNet Canada for 2024: Loan Stars - Tech Forum 2024
 
DevoxxFR 2024 Reproducible Builds with Apache Maven
DevoxxFR 2024 Reproducible Builds with Apache MavenDevoxxFR 2024 Reproducible Builds with Apache Maven
DevoxxFR 2024 Reproducible Builds with Apache Maven
 
Hyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdf
Hyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdfHyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdf
Hyperautomation and AI/ML: A Strategy for Digital Transformation Success.pdf
 
The Ultimate Guide to Choosing WordPress Pros and Cons
The Ultimate Guide to Choosing WordPress Pros and ConsThe Ultimate Guide to Choosing WordPress Pros and Cons
The Ultimate Guide to Choosing WordPress Pros and Cons
 
Passkey Providers and Enabling Portability: FIDO Paris Seminar.pptx
Passkey Providers and Enabling Portability: FIDO Paris Seminar.pptxPasskey Providers and Enabling Portability: FIDO Paris Seminar.pptx
Passkey Providers and Enabling Portability: FIDO Paris Seminar.pptx
 
Are Multi-Cloud and Serverless Good or Bad?
Are Multi-Cloud and Serverless Good or Bad?Are Multi-Cloud and Serverless Good or Bad?
Are Multi-Cloud and Serverless Good or Bad?
 
SIP trunking in Janus @ Kamailio World 2024
SIP trunking in Janus @ Kamailio World 2024SIP trunking in Janus @ Kamailio World 2024
SIP trunking in Janus @ Kamailio World 2024
 
The Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptx
The Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptxThe Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptx
The Role of FIDO in a Cyber Secure Netherlands: FIDO Paris Seminar.pptx
 
DSPy a system for AI to Write Prompts and Do Fine Tuning
DSPy a system for AI to Write Prompts and Do Fine TuningDSPy a system for AI to Write Prompts and Do Fine Tuning
DSPy a system for AI to Write Prompts and Do Fine Tuning
 
DMCC Future of Trade Web3 - Special Edition
DMCC Future of Trade Web3 - Special EditionDMCC Future of Trade Web3 - Special Edition
DMCC Future of Trade Web3 - Special Edition
 
Merck Moving Beyond Passwords: FIDO Paris Seminar.pptx
Merck Moving Beyond Passwords: FIDO Paris Seminar.pptxMerck Moving Beyond Passwords: FIDO Paris Seminar.pptx
Merck Moving Beyond Passwords: FIDO Paris Seminar.pptx
 
Advanced Computer Architecture – An Introduction
Advanced Computer Architecture – An IntroductionAdvanced Computer Architecture – An Introduction
Advanced Computer Architecture – An Introduction
 
Developer Data Modeling Mistakes: From Postgres to NoSQL
Developer Data Modeling Mistakes: From Postgres to NoSQLDeveloper Data Modeling Mistakes: From Postgres to NoSQL
Developer Data Modeling Mistakes: From Postgres to NoSQL
 
Scanning the Internet for External Cloud Exposures via SSL Certs
Scanning the Internet for External Cloud Exposures via SSL CertsScanning the Internet for External Cloud Exposures via SSL Certs
Scanning the Internet for External Cloud Exposures via SSL Certs
 
WordPress Websites for Engineers: Elevate Your Brand
WordPress Websites for Engineers: Elevate Your BrandWordPress Websites for Engineers: Elevate Your Brand
WordPress Websites for Engineers: Elevate Your Brand
 

Antimicrobials 1 Lec

  • 1. BETA LACTAM & OTHER CELL WALL- & MEMBRANE ACTIVE ANTIBIOTICS MA. LENY ALDA G. JUSAYAN, MD DEPARTMENT OF PHARMACOLOGY
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.  
  • 7.
  • 8.
  • 9.  
  • 10.  
  • 11. thiazolidine ring (A) connected to a b-lactam ring (B), to which is attached a side chain (R).
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.  
  • 21.  
  • 22.  
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.  
  • 32.
  • 33.
  • 34.  
  • 35. Resistance to β-Lactams – Gram pos.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.
  • 51.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.
  • 61.
  • 62.
  • 63.
  • 64. Cephalosporins   First Generation        Second Generation     Third Generation       Fourth Generation                      * Oral Agent Cefadroxil *   Cefaclor * Cefdinir Cefepime   Cefazolin    Cefamandole  Cefoperaxone    Cefpirome   Cefelixin *   Cefonicid  Cefotaxime     Cephalothin    Ceforanide Ceftazidime     Cephaprin    Cefotetan Ceftibuten     Cephradine *   Cefoxitin  Ceftizoxime       Cefuroxime moxalactam Ceftriaxone
  • 65.
  • 66.
  • 67.
  • 68.
  • 69.
  • 70.  
  • 71.
  • 72.
  • 73.
  • 74.
  • 75.
  • 76.
  • 77.
  • 78.
  • 79.
  • 80.
  • 81.
  • 82.
  • 83.
  • 84.
  • 85.
  • 86.
  • 87.
  • 88.
  • 89.
  • 90.
  • 91.
  • 92.
  • 93.
  • 94.
  • 95.
  • 96.
  • 97.
  • 98.
  • 99.
  • 100.
  • 101.
  • 102.
  • 103.
  • 104.
  • 105.
  • 106.
  • 107.  
  • 108.
  • 109.