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5 wac 2012

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5 wac 2012

  1. 1. Organizers ,!$e1fu. Y /oRtD fffitu} @ofMadhya Pradesh AYURVEDA FOI.]NDAT ON 1gg.J # Gofr ofChhatisqarh World Auurveda Cdnnresi & [,o4qa txpo 'Enriching Public Healttt Througtt Ayurveda' 7-10 December 2012, Bhopal, Madhya Pradesh, lndia Prime Sponsor x &6* ila€*qd- qp#ch^:!i* Ftt?fm€xcll @ *-&9.:!ii.- r.*a .?'W* * PHARMACEUTICATS EXPOA] PROMOIION COUNCIL Mininry olcomm€r.€ & lnd8try *.ry= AVS, Kottakkal AVP. Coimbatore
  2. 2. CHIEF PATRONS NATIOI{AL ORGAI{ISING CONTITIEE Shri Ghulam Nabi Azad Chair Hon;ble Minister for H & FW Gow of lndia Dr P R Krishna Kumar, AVP, Coimbatore Shri Shivraj Singh Chauhan Co-Chairs Hon'ble Chief Minister, Govt of Madhya Pradesh Dr Raghavendra Kulkarni. Hyderabad Shri Sudip Bandyopadhyay Dr Jayaprakash Narayan, Bengal uru Hon'ble Minister of State, H & FW Govt of lndia Secretary General Shri S Gandhiselvan Dr G Geetha Krishnan, New Delhi Hon'ble Minister of State, H & FW, Gow of lndia Chief Co-ordinator Shri Raman Singh Shri Chandrasekharan Nair, Bengaluru Hon'ble Chief Minister, Gow of Chhattisgarh Joint Chief Coordinator PATROITS Shri Praveen Ramdas, Bhopal Shri Kailash Vijayvargiya SCIENTIFIC COMMITTEE Hon'ble Minister for Science and Technology, Chair - Dr Ajay Kumar Sharma, Director, NlA, Jaipur Gow of Madhya Pradesh Co-Chair - Dr Ram Manohar, Director Shri Mahendra Herdia AVP Research Foundation, Coimbatore Hon'ble Minister for H & FW Medical Education Secretary - Dr Vivek Sanker, Bengaluru AYUSH, Gow of Madhya Pradesh ASSOCIATE EVENTS frlATlOl{At STEERIilG COlt$lTTEE Chair - Shri Ranjit Puranik, Mumbai Chair Co-Chair - Dr Srinivas Prasad, KLE College, Belgaum Dr Vijay Bhatkar, President Vijnana Bharati & Chairman Secretary - Dr Pawankumar Godatwar, NlA, Jaipur Board of Governors, llT Delhi AROGYA EXPO 2012 Co-Chair Chair - Shri Subharthee Dey, President, ADMA, Mumbai Dr P M Varier, Arya Vaidya sala, Kottakkal Secretary, AROGYA Clinic Management - Convener Vd Vinay Velankar, Dombiwal i Shri R A Khandelwa[ Commissioner Secretary, AROGYA Expo- DrTanuja Gokhale, Pune Dept of AYUSH. Gow of Madhya Pradesh Members Co-ordinator - DrTushar Mandlilc Bhopal INTERNATIONAL DELEGATES' ASSEMBLYIIDA) Prof O P Upadhyaya, VC. GRAU, Punjab Dr P V Appaji, Director General, Pharmexcil, New Delhi Chair - Dr KAnil Kumat Bengaluru Co-Chairs - Dr Antonio Morandi, ltaly, Dr Bhushan Patwardhan, VC, SlU, Pune Ms Pratichi Mathur, USA, Dr George Berra, Argentina Prof Umesh Ch.Sarma, VC, SSUH5, Guwahati Secretary - Dr Rajesh Kotecha, Jaipur Dr Medhavi Lal Sharma,VC, GAU, Jamnagar Prof Radhey Shyam, VC, RAU, Jodhpur Convener - DrTanuja Gokhale, Pune Prof C B Jha, Dean, Faculty of Ayurveda, BHU, Varanasi STUDENTS'PROGRAMME Vaidya Raghunandan Sharma, President, CCIM, New Delhi Chair - Dr B R Ramakrishna, Principal Prof MS Bhaghel, Director, IPGT & RA, GAU, Jamnagar Sushrutha Ayurveda College, Bengaluru Shri A Jayakumar Co-Chair - Dr Asit Panja, NlA, Jaipur Secretary General, Vijnana Bharati, New Delhi Jt Conveners - Dr Dhananjay Kulkarni, Pune Prof N P Shukla, Chairman, MP Pollution Control Board Vd Bhavdeep Ganatra, Ahmedabad Dr Sudhir Sharma, Chairman, CR|SP, Govt. of MP PUBLICATIONS AND DOCUMENTATION Shri Jayant Sahasrabudhe Chair- Shri K P Eashwar, Chennai National Organising Secretary,Vijnana Bharati Convener - Ms Reena Mehta, Delhi Ex-Officio Members DELEGATE MANAGEMENT CELL Chair, National Organising Committee Chair - Dr Sreeramji Jyothishi, Nagpur Secretary General, National Organising Committee Convener - Dr Mamata Mishra, Mumbai NATIOI{AI ADVISORY BOARD FINANCE COMM]TTEE Members Chair - Dr Akhilesh Pandey, Chairman Dr T Ramasami, Secretary, Department of Science and Technology, Private University Commission, Bhopal Government of lndia Secretary - Dr Sunil Kumar,Trivandrum Dr S Ayyappan, Secretary. Department of Agriculture Education, Government of lndia and Director General, lndian Council of LOGISTICS COMMITTEE Agricultural Research Chair- Prof Piyush Trivedi, VC, RGPV Bhopal Mr Uday KumarVerma, Secretary, lnformation and Broadcasting Govt. Secretary - Dr Madhusudan Deshpande, of lndia Arogya Bharati, Bhopal Shri Rajiv Kher, Additional Secretary POSTER PAVITION Department of Commerce, Government of lndia Prof K I Vasu, Founder-President, V'rjnana Bharati Chair - Dr K5 Jayashree, Bengaluru Dr H R Nagendra, Vice Chancellor, S-WASA, Bengaluru Convener - Dr Kamini Koushal, Haridwar Dr Naresh Trehan, Medanta, New Delhi COMMUNICATION CELt Shri Darshan 5ankar, lAlM, Bengaluru Dr Anupama Raju, llAM, Bengaluru Padma Bhushan Vaidya Devendra Triguna PR AND PUBTICITY President, All lndia Ayurvedic Congress Chair - Prof B K Kuthiala, VC, MCU, Bhopal Prof Pramod KVerma, Scientific Advisor to Convener - Shri Vijesh Lunawat, Bhopal Government of Madhya Pradesh Dr Shankar Tatwawadi, Nagpur ZONAL CHAIRS Dr B G Gopinath, Managing Trustee, Prof 5 P Bhattacharjee, (East zone) World Ayurveda Foundation, Bengaluru Dr K C Ballal, Bengaluru (South zone) DrVV Doiphode, Pune (West zone) Dr B M Gupta, (North zone)
  3. 3. Abstracts of Selected Papers for oral and Poster Presentation
  4. 4. ABSTRACTS Abstracts of Selected Papers for Oral and Poster Presentation sth World Ayurveda Congress and Arogya Expo Focal theme Enriching Public Health Thrrough Ayurveda 7-llDecemb er 2012 Bhopal, Madhya Pradesh, lndia
  5. 5. OVorld Ayurveda Foundation, 20 I 2 Published by World Al"urveda Foundation, I 07/ I , Margosa Road, Between I 3th and 1 4th Cross, Malleswaram, Bengaluru - 560 003,India Disclaimer The information contained in this publication represents those of the respective authors and nor those of the publisher, the Vijnana Bharati. tfr{itEbyWod(Station Systems Pvt. Ltd. H-35, Govindpura lndustrial Estate, Bhopal.
  6. 6. CONTENTS Foreword vtl A Jayakum ar, S ecretary-G eneral,Vijnana Bharati Frsn the. desk ef Seerehry-Geeeral IX G Geetha Krishnan' Seuetary-General,SthWorld'4yuroeda Congress andArogya Expo 2012 Preface xt Prof. Ajay Kumar Sharma, Director, National Institute of ,43turzteda,Jaipur, and Chairman, Scientific Cotnmittee, 5th IY/AC A Note from the Scientific Review Committee xtil Abstract Reviewers xv Section A: Abstracts Selected for Oral presentation 1 Section B: Abstracts Selected for Poster presentation 141
  7. 7. FOREWORD Theforld Ayurveda Congress CWAC) is back! For most people. But for us atviinana Bharati (VIBHA),$[AC is always a'work in progress'. It had a great beginning at Kochi n 2002 and is moving on thereafter from place to place carrying the message of Ayurveda, It is forever gath--' ering momentum with new sets of ideas, people (both young and old), and innovations. 7hile there is no change in the overall mission for whichWAC was instituted, the Congress has always set new goals and benchmarks challenging not only the capabilities of colleagues atVIBHA' but also those of the Ayurveda fraternity. Each time and every time. A few years ago, some of my colleagues had suggested that we organize$fAC a| a particular place each time, thereby creating a distinct identity for itself among the people. Though there is some merit in their argument, what overrides this argument is the potential of$7AC to generate awareness on Ayurveda among different sets of people in different states of the counuy. True to this line of thought, we have been able to create new friends of Ayurveda and new stakehold- ers. Today, more people, including the general public, are in the fold saying, more often than nor,'yes'to Ayurveda with an open mind.To that extentrVIBHA is happy to $hare that$fAC is meeting its objectives. The 4th edition was special in one respect: the genesis of the $7orld Ayurveda Foundation (WAF). The idea is to bring all our current and planned future activities related to Ayurveda under one umbrella. I thank all those who made it happen. JflAF is also in the process of get- ting the wherewithal to give accreditation and provide authenticity to Ayurveda institutions and educational courses nrn overseas. Among the various programmes run byVIBHA,r$(/AC holds a special place in our calendar. The other prominent ones are GIST (a programme for Global Indian Scientists and Techno- crats) and BharatiyaVigyan Sammelan (BVS).While the first edition of GIST focused on the all-important issue of '$7ater', the BVS 2012 brought together prominent scientists and techno- crats from within the country to find local solutions to the various issues the country faces. We have a similar movement in the fields of ehergy and environment too. As for the 5th edition ofWAC,I am extremely grateful to Shri Shivraj Singh Chouhan, the Hon'ble Chief Minister of the Government of Madhya Pradesh. The state government's sup- porr was invaluable in every sense of the term. My special thanks to Department of AYUSH, Ministry of Health and Family'Welfare, Government of India, for the support it rendered to (/AC over the years. Most importantly, my'Pranam'to all delegates and Ayr.rrveda experts from all over the world. lyye are humbled by the fact that you have always considered this Congress as 'the' important platform to share your knowledge and wisdom. I strongly believe that sincere efforts will never go waste. In that context, I do hbpe that the output/outcome of this Congress, which will be a tangible manifestation of your collective knowledge and wisdom, will find its deserving place in the health-care policies of not only the Government of Madhya Pradesh, but also of the Depart- ment of AYUSH, Government of India. My love to the team behindr$(/AC. Best wishes A Jayakumar Secretary-General, Vijnana Bharati
  8. 8. FROM THE DESK OF SECRETARY-GENERAL,5TH litAc... : It is not about abstracts that I would'like to write here. It is about the people and the society that they concern with. From 2002 to 2012,1have seen and felt the pulse of7orld Ayurveda Congress CU7AC), its growth as the largest platform forAyurveda, and perhaps one of the largest in the area of CAM, internationally. For me, WAC represents the changing world of Ayurveda and the people who drive that change.The most perceivable change during this decade has been the openness with which the Ayurveda'community has accepted the demand for evidence and turned around its course to enable itself to the generation of clinical evidence. Today "drug dis- covery" does not mean turning up the samhitas and "discovering" a previously not read formu- lation, but building up a case with the support of combinatorial chemistry, metabolomics and systems biology to logically defend a new combination of medicinal plants for its target (often multiple) specific clinical benefit(s). "$(rhole system research" has become the focus now and "Translational research" no longer means research in translating Sanskrit texts to Hindi and English. NlH-funded research is no longer unheard of or a distant hope. Tertiary care hospitals are opening up for integrating Ayurveda. There are more youngsters (of age 20-30 years) seek- ing Ayurveda from among a multitude of options available at multilsuper specialty hospitals than any other age group. Suddenly for the first time since I was introduced to Ayurveda, as a student in 1989, it seems there is light at the end of the tunnel.The society is putting its faith back in Ayurveda and future generation seems to choose it over other options. It is also about people. In 2002,I would not have found another Dr Ram Manohar. He rep- resents a new genre of people who lead Ayurveda with truth, science and defined systems as its core value. So do the nearly 90 reviewers from all over the world who had helped analyse and select the oral, poster, and e-publication abstracts. Youngsters like Dr Vivek Shankar deserve special mention in their dedication to the science and the responsibility at hand. The greatest change in people I saw is in the industry. Mr Ranjit Puranik has been exceptional in this regard. He would spend months of his invaluable time, planning and executing, so as to enable his competitors to compete with him, with dignity and meaning.And there had never been a time when the research community in Ayurveda had so opened up and reacted swiftly to a newly introduced submission procedure for a scientific seminar. The thousands of abstracts submit- ted online, within the compactness of the defined criteria, themselves speak of a time, for which change is "inevitability". It is also worthwhile to note that this set of abstracts shall be carried in special issues of Pubmed indexed journals of Ayurveda, which itself will be a "first-time" in the sector. I am sure that you will find these abstracts extremely useful and I hope you would be able to feel the un- dercurrent of change which they represent. Dr G Geetha Krishnan 29 November 2012 Secretary-General, 5th $7AC New Delhi Trustee : World Ayrrveda Foundation Senior Consultant: Ayurveda, Medanta Chief Coordinator: Integrative Medicine, Medanta
  9. 9. PREFACE TheWorld Ayurveda Congress had been in existence for over a decade now and had organize{ four mega events, the lst at Kochi, 2nd in Pune, 3rd in Jaipur, 4th in Bengaluru and the present 5th Conference ar Bhopal. I had the opportunity to participate in all these mega events and am proud of the opportunity to actively participate in the 3rd WAC held in my National Institute ofAyurveda. Our country has made tremendous progress in health indicators over the past many decades. In spite of the impressive progress made, a high proportion of population, especially in rural areas, still continues to be deprived of quality health care on equitable basis at affordable costs. I feel here Ayurveda can play a vital role to take care ofthe day-to-day health care needs of a vast rural population. 7e all know and everyone will appreciate thatAyurveda has a proven track record ofsuccess through ages and it is the bounden duty of all of us to bring this science into a global focus, so that benefits of this rich science is available to the mankind all over the world. As per the lforld Health Organization's Report, even today more than 80% of the world's population depends on Ayurveda and other natural systems of medicines to cure their diseases' as they cannot afford to buy the expensive medicines of the advanced world. Today, even the developed countries look towards Alrrrveda and other Indian Systems of Medicines as the last hopes for curing many of the diseases, when allopathy fails. Cure of infectious disease like AIDS, chikungunia, dengue is really the challenge to both allopathy and Ayurveda. ilfho knows one day Ayurveda and other Indian Systems of Medicines may come out with wonder drugs to cure these deadly diseases? The present 5th 7orld Ayurveda Congress will throw light on various aspects such as col- laboration with foreign countries in the field of education, training, clinical research, publica- tions, manufacturing etc. so that the Ayurvedic System of Medicine will be able to reach each every corner of the globe for welfare of mankind. The aims and objectives of this Congress will be achieved with all efforts. As the Congress is held every two years' the organizers have ample time and opportunity to sit together to analyze and churn various outcomes for implementation of the so arrived opinions and decisions for further improvement and enriching of Ayurvedic System of Medicine for acceptance globally. If this is done, I hope, we can achieve a lot for the welfare of mankind. One of the main objectives of the Congress is to discuss and elaborate the possibilities of further globalization of Ayurveda by entering into collaboration, cooperation, bilateral agreements, etc. for teaching, training, research and treatment aspects of Ayurveda and also ro initiate proper legislation and validation of Ayurveda in the countries which are inter- ested to adopt Ayrrveda as a system of medicine. Efforts will also be made to find out ways and means to increase export potential of Ayurvedic medicines to foreign countries. The outcome of the deliberations and discussions of the Congress will go a long way in show- ing the right path to the global Ayurvedic community in the need for propagation, protection and adopting Ayurveda for a long and sound health at a time when many foreign countries and narionals are rurning rowards this ancient divine system of medicine for leading a purposeful and sound healthy life free from diseases. I wish all success for this mega international event. Prof. Aiay Kurnar Shartna Director, National Institute of Ayurveda, Jaipur Chairman, Scientific Cornmittee, 5th $fAC
  10. 10. A NOTE FROM THE SCIENTIFIC REVIEW COMMITTEE A blinded peer reaiewed process to scrutinise and select abstracts... The 5th World Ayurveda Congress has taken a major step forward in introducing an onlind module based peer review system for submission, review, revision, selection, editing, scheduling and creating the abstract book in a professional manner.This has been done with a view to make the lil/orld Ayurveda Congress a platform and stepping stone for showcasing the best research happening in the field of Ayurveda. The abstract submission module has been designed to enable researchers to submit abstracts that are structured and focused, but brief at the same time. Good abstract writing is so impor- tant in scientific communication because it is the abstracts that are often seriously read to take editorial decisions and even accessed by researchers in international databases. We wanted to enforce a rigorous peer review system to enable fair evaluation of the sub- mitted abstracts. All abstracts were reviewed in a blinded manner without revealing names of authors and their institutional affiliations. There were two rounds of blinded internal review by the editorial team and many abstracts were sent back to the authors for revision. In the next step, the abstracts were sent to about 150 experts all over the world. Amongst them, more than 80 responded and scored the abstracts based on various parameters like originaliry, scientific importance, rigour of methodology, appropriate analysis and proper conclusions. In the last phase, the senior members of the scientific committee picked up the abstracts for oral and poster presentations based on the rating given by the external reviewers. Ve could select only a few abstracts for oral presentations compared to the posters and e- publication. It is not true that the best papers were selected for oral presentation. We looked at at the nature of the study and which format would be most suited for its presentation.Therefore, some of the papers selected for oral presentation represent abstract ideas because they cannot be effectively presented as posters.Whereas some concrete studies are more graphically presented as posters, they were assigned for the poster sessions. Moreoverr the 7orld Ayurveda Congress has always given importance to posters compared to other conferences. Posters are allowed to be displayed for almost the entire duration of the conference in a very visible way. There has not been much of editorial intervention due to paucity of time. However, we be- lieve that the richness of the content presented in these abstracts far outweighs the glitches that you may notice on the language front. A very important step taken by the congress is to publish the abstracts in PubMed indexed research journals on Ayurveda. Post the congress, three journals in the field of Ayurveda will publish parts of the selected abstracts as a supplement.This will make these abstracts visible for researchers around the world. The abstracts of the Congress will also be indexed in DHARA online database - www.dharaonline.org. Authors are also invited to submit their papers for publication in the official journals of the congress which are PubMed indexed and this process would be facilitated by the scientific com- mittee.
  11. 11. ABSTRACT REVIEWERS Chair l0 BaliYogitha 46 RajaseHraran S. DrAjay Kumar Sharma 11 Bavadekar Shriprasad 47 Rajendra PD Sharma Director, National Institute of 12 Bhokardankar Prashant 48 RajmohanV Ayurveda, Jaipur, Rajasthan, 13 Byadgi Parmeswarappa 49 Ranade Sunanda India 14 Christian Kessler 50 Reetu Sharnra (Germany) 5l Sanjay Kumar Co-Chair 15 Dinakara Sharma M 52 Sanjeev Rastogi Dr P Ram Manohar 16 Dixit Upendra 53 Santosh Kumar Bhatted Director, AVP Research 17 Dornala Sathyanarayana 54 Sawikar Shriram Foundation, C oimbatore, 18 Durgawati Devi 55 Sekhar Namburi UR Tamil Nadu,India 19 Gopesh Mangal 56 Shailaza Bhamagar 20 HankeyAlex (UK) 57 Shamsa Fiaz Secretary 21 Hiremath Shobha 58 Shankar Rao K Dr M KVivek Sankar 22 llavarasuJudu 59 Sharad Maroti Porte Head, CCR' I AIM' 23 Indtt Bala Kaul 60 Shashi Kiran Bengaluru, Karnataka, India 24 lai Prakash SinCh 61 Sivaramaprasad 25 Jaiswal ML Vinjamury (USA) Editorial Members 26 Janardhan Krishna 62 Sreevaths Suiith Subash 2? JoglekarVP 63 Subramanya S Somit Kumar 28 Joshi Chintamani 64 Sudipt Rath Anita Mahapatra 29 JoshiYashashree 65 Sumit nathani AramyaAR 30 Kashinath Samagandi 66 Sunil Kumar Sujithra RM 31 Kishore Patwardhan 67 Sunil KumarYadav Ramya 32 Krishnan Geetha 68 Supriya Bhalerao Shreelatha 33 Kulkarni Omkar 69 Suresh P Shriranjini 34 KulkarniYogini 70 Sushila Sharma Ashwini 35 ManoVenkattaman 71 Swapana B (usA) 72 Syal Kumar (GermanY) External Reviewers 36 Mita Kotecha 73 Thangavelu Madan (UK) I Ajay Kumar Sahu 37 Nagendra HR 74 Toshikhane Hemant 2 Anand Dhruva (USA) 38 Nageshwar RaoV 75 Ubale Sandeep 3 Anita Sharma 39 Narayana DBA 76 Venkateshwarlu G 4 Antonio Morandi (Italy) 40 Nene Priya 77 Venugopal SN 5 Ashwini Godbole 41 Pankal Kundal 78 Vikas Bhatnagar 6 Ashwini Kumar Raut 42 Phadke Aashish 79 Vinay Mahajan 7 Badole Sachin 43 Prasad BS 80 VinodTG 8 Baghel MS 44 Priyadarshini Shantala 8l Yadav CR g Balasubramani SP 45 Rajagopala S 82 Yogesh Murti
  12. 12. ef7a@ea SECTION A Abstracts Selected for Oral Presentation qQ'aea
  13. 13. IOOOi-r Efficacy of the toasted garlic with jaggery in the management of kastartava TANRGunaratna : Purlrose: A randomised placebo controlled study was undertaken to examine the effect of a traditional remedy consisting of two plant ingredients (Garlic - Allium sathtum and Jaggery - Caryota urens) for the management of Kastartava (dysmenorrhoea). Mettrod: Sixty female volunteers were selected from GampahaTickramarachchi Ayurveda In- sritute, IJniversity of Kelaniya, Sri Lanka. Test group (30) was treated with remedy (25 g of toasted garlic with 5 g of jaggery) and Placebo group (30) was treated with 30 millilitres of distilled water at the onset of menstruation pain for a period of three months Pain and other symptoms were rated using five point scales Result: P-value according to the analysis of the Test Group in the comparison of before and after treatment and first, second and third month were less than 0.05. Significant relief in pain was observed in the study group at the end of three months. Conclusion: Garlic exhibitsVikashi guna (antispasmodic) andVedhana shaman (analgesic) ac- tivity. Its antispasmodic activity relieves spasms of the voluntary and involuntary by strengthen- ing nerves. Garlic and jaggery decrease aggravated Apana vata and Kapha in the Artava vaha srothas and increase the Pitta. This remedy is, therefore, helpful in regulating menstrual flow and relieving pain. Statistical analysis suggests (p<0.05) that toasted garlic with jaggery is an effective remedy for I(astartava. lOOlr-r Protective effect of yashtimadhu (Glycyrrhiza glabra) against side ef- fects of radiation/chemotherapy in head and neck malignancies Debabrata Das, H M Chandola, SK Agarwal 1 ProJessor and HOD, Dept of Radiotherapy, M P Shah Medical College ts G G Hospiial, Jamnagar Purpose: This study aims to evaluate the scope for minimising the radiation induced mucositis, skin reaction, xerostomia, change in voice etc with an Ayurvedic Ghrita preparation i.e.Yashti- madhu Ghrita. Health-related quality of life measures have been used as an outcome measure. Method: Inclusion Criteria- Patients between 30 and 60 years with histopathologically proven head and neck malignancies and who had not irritially been treated by Radiotherapy subject to Hb% -->9% and Serum Protein within normal limits. Exclusion uiteria - Those on palliative course of treatment, who have taken Radiotherapy earlier, and below 30 years and above 60 years with history of Hypertension, Cardiac Ailments, Diabetes and those allergic to Platins were excluded from the study.Yashtimadhu root was subjected to pharmacognostical study and the raw drug and its powder was used for microscopic assessment and authentication.
  14. 14. Oral Presentation Resule Thble No. 2: Comparison of side effects berween the study groups (A, B and- C) and control grqup D showing Groups and reactions before and after treatment (x2 p). p x2 Group A: Mucositis 6.71. <0.001 2.04 <0.001, Skin reactions 0.34 >0.1 0.34 >0.1, Xerostomia 0.0r4 >0.r 4.3g >0.r, change invoice 0.014 >0.1 14.39 <0.001 Group B: Mucositis 3.20 >0.1 8.98 <0.001, Skin reactions 6.g2 <0.001 0.46 )0.1, Xerostomia O.I2 >0.1 2.30 >0.l, Change in voice I l.5g <O.OOL 14.42 <0.001 Group C: Mucositis 1.50 >0.1 1.22 >0.1, Skin reactions O.OZ >0.1 2.58 >0.1, Xerostomia. 1.22 >0.1 0.86 >0.1, Change in voice 4.03 >0.1 2.26 >0.1 Conclusion: The intensity of radiation and chemotherapy induced mucositis was reduced to a great extent enabling food intake. The hematological levels were maintained within normal lim- its enabling timely administration of chemorherapy. The side effects were more visible in pitta- dominated prakriti since radiation is similar tcr Agni and chemotherapy to Tikshna aushadhi. There were no side effects of the trial drug. Xerostomia symptoms were persistent and the trial drug had no effect on this particular side effect. I 0028 Management of progressive glaucomatous optic neuropathy- a neo ayurvedic approach Veeranagouda S Adoor Purpose: Ganglion cells with nerve fibre layer contribute a substantial fraction to the retinal thickness (RT), which is usually decreased in Glaucoma. This is measured by optical Coher- ence Topography (OCT), which enables objective noninvasive evaluarion of the posterior pole and could become helpful in diagnosis of glaucoma before the onset of functional damage. Even visual fields analysis and retinal sensitivity threshold measurement also enable the assessmenr of progression of glaucomatous optic neuropathy. In this study, we wanted to compare the rate of progression/halting of progression of optic neuropathy between two treaffnent modalities by assessing all these parameters. Method: Progression of glaucomatous optic neuropathy was assessed between 20 eyes treated with modern antiglaucoma drops alone (Group-A) and 20 eyes treated rvith both modern an- tiglaucoma drops and Ayurvedic management (Classical line of management with srress on chakshusya-rasayana) (Group-B) for 90 days. In both grqups, visual acuity, Retinal Nerve Fibre I-ayer (RNFL), Visual fields, Applanation Tonometry, DO/IDO were tested periodically and datas collected. Follow up 2 months. Result: After completion of 3 months of trearment in Group-A, 7 eyes RNFL was unaltered, with significant decrease in RNFL in 13 eyes, visual field defect found to be worsened in g eyes, unchanged in l2 eyes. Retinal sensitivity was found to be decreased in l5 eyes. After completion of 3 months treatment of Group-B, the RNFL thickness was unchanged in 13 eyes and slightly improved in 2 eyes, worsened in 5 eyes, with no significant changes in visual fields of all parients, however retinal threshold sensitivity was found to be,increased in z eyes. Conclusion: A classical ayurvedic line of treatment especially of chakshusya-rasayana in nature if given as adjuvant with modern antiglaucoma management, rhe rate of progression of glauco- 4 ABSTRACTS . 5thWorldAyurvedaCongressandArogya Expo2012
  15. 15. Oral Presentation surtous optic neuropathy can be significantly slowed down or can be halted with overall visual satus improvement of the patient. lO0ll,l Role of uttarbasti in cases of benign enlargement of prostate Ramesh Rajguru Purgrose The aim of the study is to evaluate the efficacy of uttarabasti in cases of benign en- largement of prostate. Investigations like USG were done to assess prostate size and post void urine residue in bladder. Also routine investigations like CBC, urine tests were done. Method: Patient should lie on bed. After cleaning penile area, sterile rubber catheter is passed through penis till it reaches urinary bladder. Bladder is evacuated completely by giving pressure over basti area. Then 20 ml SAHACHAR taila is administered in the bladder. Patient should lie on bed for half an hour. Pulse and blood pressure are recorded and nadisweda is given over Basti area to avoid further pain. Medications used are Gokshuradi Guggul and Chandraprabha vati and Chandanasav. Medications was given for one month and after one month Rasayan churna was administered for two months. Result: The effects of this treatment was observed in 18 patients. Patients reported passing of oil with no pain while passing urine after two days After a week, burning and str:iin during urination was relieved.Within two weeks the patients were symptom free. Patients also reported improved sexual activity after the procedure. Conclusion: Uttarbasti is helpful in management of cases of benign enlargement of prostate This procedure was tried on patients in rural as well as in urban areas and patients are being followed up on a long-term basis. I OO,l2 A comparative clinicalevaluation of thyromax powder against thy- roxine sodium in the management of hypothyroidism Nitin Ujjaliya, Remedevi R, S V Krishnankutty 1V P SV'4yurveda College,2 Maulana Muhispecility Hospital Purpose:The thyroid gland regulates metabolism of the body by virtue of its hormones. Insuffl- cient levels of thyroid hormone cause signs and symptoms such as slower metabolic rate, weight gain, sleepiness, pufri face, dry and cool skin, as well as others. This condition collectively can be called as Hypothyroidism. Hypothyroidism is most common in women than men. According to a study, it affects 3.9To people with 9.4% subclinical condition.The sole available treatment for this in conventional science is HRT which is not always free from side effects and has to be taken lifelong. This study was aimed to search an option for Hypothyroidism in terms of herbs. Method: Traditionally practised drugs Gu6. uca Sawam and Amalaka car6'am was taken in a combination named Thyromax powderrM which was standardized before commencing with clinical trial. For the standardization of study drug; SOP guidelines were followed and HPTLC profile of individual content andThyromax powder was prepared. A controlled clinical trial was planned with 20 newly diagnosed participants, who were not exposed to any medicament, with Thyroxine sodium in conuol group for the duration of 3 month. Assessment was done on the basis of six subjective parameters and thyroid function test. Organized by World Ayurveda Foundation and Government of Madhya Pradesh ABSTRACTS 5
  16. 16. Oral Presentation Result: On statistical analysis, study drug showed a high positive correlation on subjective pa- rameters while control group showed significant result on T3 and T4 levels. Both the groups were found statistically insignificant on TSH level. Conclusion: HPTLC profile showed four chemical constituents in Gu6. uca Sawam and 11 peaks in Amalaka car6lam extracts. There was no negative impression in HPTLC profile of Thyromax powder due to combination. Thyromax powder is found to be more effective in re- ducing the subjective parameters. Thyroxine sodium is found to be more effective on T3 and T4 parameters.Thyromax powder andThyroxine sodium both are found to be insignificant on TSH level. roo48 Epidemiological study of metabolic syndrome with randomized con- trol trial of arjuna (Terminolia orjunaw. & a.) and agnimantha (Premna integrifolia linn) Ashish Tiwari, Himmat Lal Dhaker, Pawankumar Godatwar, Bal Krishan Sevatkar Purpose: In the past few years Metabolic Syndrome (MS) has become the leading problem of today world. By 2A25,three out of four people with diabetes will be living in third world coun- tries, and similar trends are likely for the other components of the syndrome. On keeping the above fact in mind, the present work was planned to study the epidemiological aspect of meta- bolic syndrome and evaluate the efficacy certain herbal drugs to break the pathogenesis of MS. MethodiThe present work was divided into two phases. Phase 1: Epidemiological study - 1 100 subjects in the age group of 18 to 70 of both sex (exclud- ing pregnant women) were included after informed consent. Phase 2: Randomized Clinical trial - On the basis of inclusion and exclusion criteria 100 diagnosed metabolic syndrome cases (63 male and 37 female) were randomized in two groups - Group-I : 50 (35 male, 15 female) cases treared with 6 g BD Arjuna Churna., Group-II : 5O (32 male, l8 female) cases treated with 6 g BD Agnimanth churna. Result: In the epidemiological study, 500 overweight (BMI 23 KglM3) subjects were found and incidence of overweight subjects was 454 : 1000 (45%). Out.of all overweight subjects 200 M.S. subjects were found. So incidence of M.S. subjects was 400 : 1000 (40%) and 182 : l00O (18.2%) in the age group of 18 to 70 years general population of Jaipur in Rajasthan. Conclusion: Inthe RCT,bothArjuna andAgnimanthashowed statisticallysignificant (p<O.0Ol) efficacy on parameters such as weight, BMI, visceral fat, body fat%, WHR, Blood glucose and lipid profile. Arjuna emerged better in symptoms such as- Hriddrava, Nisha-mutratar Shirah- shoola, Svedadhikya, and Alpabala while Agnimantha was better in Alasya, I(oshthabaddhata, Chalasphikaudarastana, Krichchha Vyavayata, I(shudhavriddhi, Nidrad-hikya, Kshudrashwasa' Pipasadhikya, Bahumutrata and Bhrama. 6 ABSTRACTS . 5thWorldAyurvedaCongressandArogyaExpo20l2
  17. 17. Oral Presentation r0062 Fluorescence and sound producing nature of pathogens: an ayurvedic perspective Abhilash Mullasseril Purpose: Recently modern scientist are keenly researching on the illuminations produced by the microbes. According to microbiologists the colonies of bacteria especially pathogenic ones can fluoresce and make characteristic smells. It is the modern discovery that the bacteria can make sounds and they communicate with each other.The modern scientists use the word Quo- rum Sensing for the method of communication. The invention of the device known as nano ear, which uses the gold nano particles can enable the human to hear the voice of bacteria as the German inventers published n 2olz.The aim of this paper to correlate both Ayurveda and modern findings. Method: Classical Ayurvedic texts along with the commentaries were carefully studied to com- pile information on microbes and their flourescence and sound producing nature' Result: It was observed that there is evidence in the ancient texts to suppose that the an-cient Ayurvedic experts had knowledge about the flourescence and sound producing nature ofpatho- gens. Conclusion: The chapter,of Krminidana of Madhavanidana provides evidence that the an- cient Ayurvedic physicians had knowledge of microbiology and pathogens that draw parallels with contemporary scientific findings. l0065 Consumer approach of health and Ayurveda Sagra Szaba,Viktaria Szente, Zoltain Szaka;ly Purpose: The aim of this study was to explore the differences of health interpretation be-tween people with Ayurvedic approach and non Ayurvedic but health conscious approach. rWrhile Ay- urveda has a holistic approach to health, the European medicine focuses on the physical aspects (bio-medicinal model). Although theoretically a complex interpretition of health (bio-psycho- social model) is the most accepted in Hungary, we examined whether it prevails on a practical level. Method:l$[e carried out a representative survey (N=1000) to examine the health-related knowl- edge and behaviour of the Hungarian population. To achieve deeper understanding of the sub- iect, we carried out two focus group discussions.We selected health conscious people in the first group and ayurvedic oriented people in the second group to compare their attitudes towards health. Result: The results showed that the majority of the Hungarian population (83.2%) has recog- nised that health is more than the bio-medicinal approach, it builds up of physical, psycho- logical, mental and social factors but in most cases we found huge gaps between recognition and action. During discussions the Ayurvedic oriented group construed an interpretation that contained all the five health dimensions of WHO and mentioned spirituality as an additional dimension, while the health conscious group mainly emphasized physical health. Jfe also asked the participants about their own health behaviour and found the same pattern. Organized byWorld Ayurveda Foundation and Government of Madhya Pradesh ABSTRACTS 7
  18. 18. Oral Presentation Conclusion: It can be stated that the Hungarian population theoretically admits an integra- tive model of health but it does not appear in their health behaviour. It seems that Ayurvedic orientation contributes to bringing knowledge to practice. Ayurvedic oriented people have more complex interpretation of health and are willing to do more for their health, so they are a good target group of prevention campaigns and health care services, It also suggests that the spread of Ayurvedic approach could contribute to better health behaviour in Hungary. I OOTzl Aclinicalstudy on shweta pradar (leucorrhoea) and its management with nimbadiyoga Poonam Choudhary, Grishma Solanki, Luxmipriya Dei Purpose: Intro:duction'Leucorrhoea, the abnormal vaginal discharge is quite frequently met in day to day gynecological practice. The7orld Health Organization estimated that there arc 333 million new cases of curableVulvovaginal infections fl/Vls) per year. A study in India has shown that the prevalence.of reproductive tract infections was 37 .O%o based on symptoms and 36.70/o by laboratory investigations, including3l%o Candidiasis, 3olo Gonorrhoea, 2o/oTrichomoniasis and 45o/o Bacterial vaginosis. Method: 58 patients of reproductive age group with complaint of Shwetapradara were selecred from the O.P.D. of I.P.G.T. & R.A., and were investigated with the help of wet vaginal smear by aid of pathology department of institute. Inclusion criteria of patient: Only married women aged 18-50 years.,The patients having clinical signs and symptoms of Shwetapradara (Leucorrhoea). Exclusion crireria of patient : Unmarried women, Pregnant women, Patients of Tuberculosis,VDRL, HIV Gonorrhoea, etc. and Genital malignancy, Congenital and other pathologies of reproductive rracr, Trial Drug : I NimbadiYoniVarti (I.{imba Patra,Triphala,Yavakuta, Sphatika and Madhu) of 3 g as vaginal suppository at bed time for duration of 7 days and follow up after I month. After completion of the course, wet vaginal smear was repeated to get the results of treatment. Follow up for re-occurrence of infection was carried out for I month wirh 15 days interval. Result: Statistically highly significant (P<0.001) ,..rrir, were found inYonigata Lakshalana i.e. Yonisrava (93.15%),Yoni Daurgandhya (99:16%), Srava consistency (96.77%),Yoni Kandu (94.92%o)'Yoni Daha (100%) andYoniVedana (100%). Provided 100% relief in vulvitis while relief in other local pathologies like vaginitis (97.37%), cervicitis (100%) and on local tender- ness (100%) were statistically highly significant (P<0.001). Relief in fungal hyphae (96.67%) and in pus cells (93.39%) statistically highly significant (P<0.001), while on trichomonas vagi- nalis 100% relief was obtained. Conclusion: Nimbadi yoni varti is safe and effective medicine for management of Leucor- rhoea. I OO..l5 Effect of phalaghritha yonipichu in prasramsinl yonivyapath Chethana Kumari Purpose: Among the various phases of women's life- pregnancy, parturition and lactation plays a significant role in perineal laxiry which is further compromised due to repeated child birth, menopause etc. This perineal laxity leads to uterine prolapse which can be co-related to Pras- 8 ABSTRACTS . 5th World Ayurveda Congress and Arogya Expo 2012
  19. 19. Oral Presentation ramsini yonivyapad. Adding to these malnutrition, debility, lack of adequate post natal care a1yw a days, further contributes to the condition. At present, 6,00,000 women are affected by rhis condition and among them, 2,00,000 require immediate treatment. At this juncture all eri*ting measures of treatment were said to be inadequate in recreating the lost stability and integrity of the pelvic support. Hence, a measure where the duration of hospital stay is reduced, is non-invasive, stress free was the need of the hour. One such therapy explained in classics is snehana, (olearion) swedana (sudation) and pichudharana (application of cloth dipped in oil) wtich were adopred in the study. For this a well-known drug, Phalaghritha, was selected, in the brm of pichudharana. Dlethod: The present study was carried out on 20 patients who were divided into two groups. The above said line of treatment was followed in 10 patients with Phalaghrita (group 1) and anorher 10 patients with Goghritha (group 2). Follow up was done 15 days after the treatment and I month duration. Result: The overall iesults showed marked improvement in 2OYo, moderate improvement in TOYo and improvement in 10 % of patients in group 1. Conclusion: Phalaghrita showed significant results in symptoms like feeling of mass per vagina, back pain, cystocele and cough reflex. It relaxed perineum and tone of muscles. Hence, the pres- ence of pichu in the vaginal canal not only plovides mechanical support but better absorption of the mediated oil, which in turn helps to provide better strength to the prolapsed tissues. loo$7 The role of haritaki avaleha in the management of tamakshvas (bron- chialasthama) Omprakash Dadhich Purpose: Among the disorders affecting the Pranavahasrotas (Respiratory system)' Tamaka swasa is an important disease due to its higher and widespread incidence, chronicity and pro- gression to grave condition in acute phase. The disease, Tamaka Swasa is characterized by par- oxysmal acacks of Shvaskashtata (breathlessness), Kasa (cough), Pinas (coryza). The aim of present study was to access the efficacy of the Haritakyadyavaleha in Thmaka swasa (Bronchial Asthma). Method: Total 50 patients ofThmaka Shvasa having symptoms like shvaskashtata, shvas, pinas, and parshvashoola were registered for the present study. Special case record form was prepared. Scoring and gradation was done to assess symptoms mentioned in Ayurvedic texts before and after treatmenr. They were randomly divided into two groups. Group A: -In this group 25 pa- tients of Thmaka Shvasa were given Haritaki Avaleha (5 g twice a day) with anupana of ushna iala for 45 days. Group B: 25 selected patients ofTamaka Shvasa were given placebo for 45 days. For the assessment of the results, guidelines given by classical text ofAyurveda were considered' Parameters used were AEC (Absolute Eosinophil Count), Pulmonary Function Tests such as FVC, PEF& and FEVI. Students paired and unpaired t test was applied for analysis of col- lected data. Study was carried out at National Institute of Aprurveda, Jaipur. Result: In group A significant results were found in Shvasakashtata (58%) and decrease in the frequency of Shvasa (54%). Significant results were found in reduction of duration of Shvasa (48%) and Pinasa (81%). Conclusion:Vatakapha pradhana Samprapti may be correlated with pathophysiology of asthma like inflammation and endo bronchial obstruction. It can be concluded from the study that the Organized by World Ayurveda Foundation and Government of Madhya Pradesh ABSTRACTS 9
  20. 20. Oral Presentation trial drug Haritaki Avaleha can be successfully used in the patients withTamaka Shvasa (Brpn- chial Asthama). No adverse effects were noted during the study. to0!)$ Effect of garbha poshana vati in garbha poshana w.s.r. to IUGR Shubha Muddanna,Sunita Siddesh,Jayasudha G C Purpose: When the fetus does not grow properly after attainment of sanjatasara, this condition is known as upavistaka.This can be correlated to intrauterine growth restriction (IUGR). Babies whose birth weight is below tenth percentile of the average for the gestational age is known as intra uterine growth restriction. In developing countries the overall incidence is about 2-8%. The incidence among the term babies is about 5oh and that of the post term babies is about 15%. These babies were at significantly greater risk for severe pre-eclampsia, fetal distress, op- erative intervention and lower APGAR score. It was the need of the hour to find low cost, easily available and effective remedy. Alrrrveda has mentioned the utility of Garbhini paricharya and Garbha poshana for the management of upavistaka using santarpana and bhrumhana for growth and development of the fetus. For this a clinical trial was conducted to evaluate the efficacy of Garbha-poshana vati consisting of Shatavari, Ashwagandha and Bala which were well known for Rasayana, Bhrumhana and Balya were selecred in the management of IUGR. Method: 30 patients with signs and symptoms of IUGR from OPD and IPD of Aryangala Vaidyak Mahavidyalaya, Satara - between the age group of l9-30 years were selected. Garbha- Poshana vati was administered twice daily after diagnosing IUGR in second tri-mester till deliv- ery and the results were studied on birth weight of new born. Result: In second trimester the effect of the drug was proven statisticaliy significant. The birth weigft of new born up to 2450 gwas l7%o, above 2450 gwere 40o% and above 3250 g 43%. Conclusion: Garbha Poshand Vati was found to be effective in conditions like Upavistaka Garbha correlated to Intra lJterine Growth Restriction (IUGR) as reflected in rhe birth weight of the children. IOIOO Role of sukumaragritha in prasava Shweta Dindur Purpose: Labour is accompanied by intense and prolonged pain. Child birth is a very dy- namic process and the woman needs to be well prepared for it. Prophylactic value of ante-natal supervision is so much tested and recognized, that it is needless to stress its importance. The contemporary system uses analgesia and anesthesia to reduce pain during labour but have no proved measures to shorten the l st stage of labour. fn Ayurveda similar efforts are being incor- porated by means of drugs, among them there are many formulations for the pregnant women to deliver with ease. Sukumara Gritha which is used to correct vata dosha has been Selected for the present study. Method:The present study, patients were selected from the OPD and IPD of S.K.A.M.C.H.&R. C, Bangalore comparing 2 groups, in group A- 20 patients were adminis-tered with Sukumara Gritha 1 month before EDD. In Group B, 20 patients were adminis-tered with a placebo. Con- 10 ABSTRACTS . 5th World Ayurveda Congress and Arogya Expo 2012
  21. 21. Oral Presentation tinuous observation was done for the progress of labour using Partogram and Bishop's score. Result: Results were calculated and statistically analysed using paired and unpaired t-test. The test showed significant difference within the group. Comparison between two groups also Sowed significant results for first stage of labour. For second and third stage no difference was found. Group A- showed better cervical ripening and shortened the number of hours in the first stage of labour compared to Group B. :" Conclusion: Sukumara Gritha is a proven drug to achieve earlier cervical ripening, de-creased amount of pain experienced by the women and shortening of the duration of first stage of la- bour. Dytocia is one of the contributing factor for increased recourse to Caesarian section. Su- kumara Gritha facilitates easy delivery and prevents the need for Caesarian section. ror02 The role of krishnabola (AIoe barbodensis) in the management of ar- tavkshaya w.s.r. to apanvayu vikriti Swati Khandale, Bhaskar Shyamkuwar, Omprakash Dadhich t 8 nOb, nept of Shairkriya, Goaernn'tent '4yurzted College, Nagpur hofessor Purpose: In present era, Artavkshaya (oligomenorrhoea) is becoming a problem due to life style changes and excess physical and mental stress.All menstrual disorders are due to vitiation of apana vayu. Krishnabola (Aloe barbendis) is mentioned in Ayurvedic texts for the treat- ment of artavakshaya due to its artavjanak (emmenagogue) property. The aim of the study was ro access the efficacy of Krishnabola in patients who were suffering from artavkshaya (Scanty menses, increased inter menstrual period, and decreased duration of menstruation) and on the functions of apanvayr. Method: The artavjanak (emmenagogue) activity of the Krishnabola (Aloe Barbadensis) was studied in women who were suffering ftom Artavkshaya (Scanty menses, increased inter men- strual period, and decreased duration of menstruation). Clinical trial was carried out at Gov- ernment Ayurved College, Nanded (M.S.) on 80 patients of aartavkshaya in two groups. In ex- perimental group 100 mg of krishnabola powder was given orally with luke-warm water before meal twice a day to 40 patients and in control group placebo (Indian arrow root powder) was administered for three consecutive menstrual cycles. Then the effect on functions of apanval'u and duration of menstrual period, inter menstrual cycle period, amount of menstrual blood were observed. The data was analysed by statistical z-test. Charaka Samhita, Sushruta Samhita' Asfrtanga Hridaya, Bhavprakash, Indian Materia Medica, Text book of Glmaecology were con- sulted for relevant information. Result: 1) Krishnabola increased the amount of menstrual blood (72%)' period of menstr- uation and decreased inter menstrual period (69 %) as well as incidences of dysmenorrhoea (66%).2) Krishnabola improved the functions of apanvayu' Conclusion: The collected data points to the role of krishnabola (Aloe barbadensri) in the man- agement of artavkshaya. Being emmenagogue, krishnabola increased amount of men-strual blood, duration of menstruation and decreased inter menstrual period significantly. Statistical z test showed significant results. Organized by World Ayurveda Foundation and Government of Madhya Pradesh ABSTRACTS 11
  22. 22. Oral Presentation I OI OrT clinical evaluation of a herbal compound (GH-99) in the patients of acute hepatitis-B Girendra Singh Tomar Purpose: Hepatitis B is a leading killer among all infectious agents and is responsible for he- pa,tocellular catcinoma (approx. 80%) and cirrhosis of liver (approx.68%).There is no cure for this dreaded disease in western medicine so far. Supportive measures are usually practiced for its management. Ayurveda, the holistic science of healing has got a treasure of valuable herbs for the treatment of all liver related disorders. Keeping this background in the mind present study has been plarined to evaluate the efficacy of the herbal com-pound GH-89 in acute cases of hepatitis B. Method: Present study is a clinical evaluation of a herbal compound (GH-89) in the patients of acute hepatitis B.The test drug contains Kalmegh, Kutki, Bhumyamalaki, Guduchi, punarnava, Bhringraj, Pittapapda, and Daruharidra. 180 patients, both males and females of varying age groups of acute hepatitis B were selected for this clinical trial. The patients were diagnosed on clinical, biochemical as well as serological parameters. The assessment of results was done us- ing both subjective and objective criteria. Subjective criteria consisrs of symptoms like anorexia, icterus, indigestion, weight loss, fatigue, itching, fever and hepatomegaly. All the *y*p,o-, *.r. graded as 0 = absent, I = mild,2 = moderate,3 = severe. Similarly objective criteria used were liver function test (Serum bilirubin, AUI, AST, alkaline phosphatase, serum protein, A:G ratio) and viral marker HBsAg. Result: All the patients were having altered liver function test values and HBsAg was positive in all the cases before treatment. After average duration of three months, 75% (I32) cases cleared the antigen. Apart from this there was highly significant reduction in serum Bilirubin, AST, ALT and Alkaline phosphatise levels. Moreover 90% patients restored normalcy on sympromatic cri- teria too. No case developed complication of this series. Conclusion: This study shows that the herbal compound (GH-89) is very effective in the man- agement of patients suffering from Infective hepatitis B. Conclusion: It shows this herbal compound (GH-89) is very effective in the patients of Jaun- dice of Infective hepatitis B. r0roG lmportance of drug standardisation in accordance with example of sarpaga nd ha (Rou wolfi a serpe nti n el Dr Sajeev Poovathady Padmanabhanan Purpose: Authentication, availability and conservarion status in accordance with IUCN is the strategic line of thought about medicinal plants used in Ayurveda in this era. In generalised thought we think that Ayurvedic drugs are free from side effecrs bur now a days the drugs con- suming has a chance of adulteration and contamination with different circumstances. Different standard operating procedures are adopted to ensure genuineness, identity and quality of herbal medicines. It is also essential to establish internationally recognised guidelines for accessing the raw material quality. This study attempts to illustrate standardisation of raw material through the example of Rauwoffia serpentina. 12 ABSTRACTS . 5thWorldAyurvedaCongressandArogyaExpo20l2
  23. 23. Oral Presentation Method: Rauwolfia serpentina contains a number of bioactive chemicals including ajma-line, deserpidine, rauwolscine, rescinnamine, reserpine, reserpiline, and serpentinine'7e conducted omparative pharmacognostic and phytochemical studies on Rauwolfia serpenina with its adul- tsnants and substituents. Result: Rauwolf.a serpentinais substituted with following species like Rauwotfia vomitoria, Rau- w micrantha and Rauwolfia canescens which contains the alkaloids reserpine and is adulteratqd with the roots of species of Rauwolfia d.ensiflora and Rauwolfia perakensis which do not contain reserpine.rffhile conducting powder microscopic studies there is characteristic structural devia- rffhen these drugs are added in the manufacturing don in adulterated and substitutecl samples. process of Ayurvedic medicines, it results in inactivity of the formulation or undesirable effects. Conclusion: The study concludes that the genuineness or purity of rnedicines is the key point for credibiliry of Ayurvedic science and that rigorous standardisation and quality control studies can preserve the genuineness of Ayurvedic medications. lololt Prativish chintha ras in the management of Dhatura poisoning Babita Singh Purpose: Agadatantra is one of the incredible branches of indigenous branches derived from the ancient science of Ashtang Ayurveda. It is still being practiced extensively espe-cially in ru- ral and tribal areas. Dhatura is an important deliriant poison grouped under sthavara upavisha and phalavisha. It affecrs the Central Nervous system. Dhatura is important ingredient of large number of medicinal formulations. It works as a best medicine when it is used in correct man- ner or otherwise it may cause adverse effects and may also be fatal. In India dhatura is stupef,'- ing poison prior to robbery kidnapping and rape. Dhatura poisoning is very common in India' Dhatura is also known as road poison. teatment of poisoning includes removal of unabsorbed poison, use of antidotes, elimination of ab-sorbed poison, treatment of general symptoms and maintenance of general condition of patient. Antidotes play the major role in management of poisons. In the Ayurvedic text,, Basavarajeeyam, Chincha Rasa (Tamarind) has been described io be possessing antidote action to counter toxicity of Dhatura. This study attempts to establish the activity and mechanism of action of chincha rasa against toxic effects of Dhatura by means of chemical analysis. Method: 1) Collection of drugs, 2) Authentication of three drugs in Govt. authorised institute, 3) i) Preparation of Chincha rasa (According to Charaka), ii) Preparation of Chincha pakwa phal (According to Sharangdhar), 4) Physical and Chemical study of Dhatur seed, i) Prepa- ration of Dhatur Churna (according to Sharangdhar) and Analytical Study of three drugs, 5) Methods of determination of an antidote. Result: Laboratory experiments were carried out to obtain values of specific parameters for Dhatur seeds, chincha patra ras (tamarind leaf juice) and chincha pakwa phal (ripe tamarind fruit). Conclusion: On the basis of observations and results found in chemical study and reported literature, the study came with the following conclusions. 1)The chincha patra rasa and Chincha pakwa phal rasa both contain Hordenine which is the alkaloid. It has the antibacterial and anti- biotic properties. Hordenine specially stimulates the central nervous system due to which it can control the symproms like unquenchable thirst, muttering, Delirium (indistinct and inaudible words unsteady gait.) 2) Because of tannins, Chinchapatra ras and Chincha pakwaphal ras have Organized by World Ayurveda Foundation and Government of Madhya Pradesh . ABSTRACTS 13
  24. 24. Oral Presentation astringent property, which counteract the toxic symptoms of Dhatur like dermatitis, rash and exfoliation of the skin. 3) Because of glycosides and tannins, chincha patra rasa and chincha pakwaphal have diuretic properfy rvhich counteract the toxic symptoms of dhatura like urinary retention and inability to pass urine. 4) The tartaric acid present in chincha patra ras and chin- cha pakwaphal ras causes gastric irritation and thus induces vomiting. The effects of dhatura poisoning can be reduced with the immediate vomiting. 5) Because of tannins chincha patra ras and Chincha pakwa phal have astringent property. Thus it controls the rise in temperature in Dhatura poisoning. 6) Chincha patra ras and Chincha pakwa phal ras have flavonoids (Vit. P. and Citrin) which strengthens the blood vessels.Thus it is useful in lowering blood pressure and also has anti-inflammatory properry. Therefore it can prevent arrhythmia produced in Dhatura poisoning and maintains the blood pressure and prevents heart atrack. 7) The Chincha patra ras and Chincha pakwa phal ras have vit. 'C' which lead the blood circulation rowards the heart which prevent the cardiac arrest produced in the Dhatura poisoning. Because the death in the Dhatura poisoning is resulted from heart failure. 8) Chincha patra ras aqueous extract Io/o and I 0% has the pH of 5.9 I and 5 .45 and the pH of chincha pakwa phal ras aqueous extracr of 1%o and 10% has pH of 4.72 and 4.50. Both are acidic but the pH of Dhatura in aqueous exrrac-t of 1% is 8.19 and 8.00. That is why they neutralize each other and reduce the toxic effect of dha- tura. Similarly, the action of chincha rasa can be explained through the concepts of Ayurveda. Itrll2,,l lmpact of climate change on medicinal plants: a review Harish B S Purpose: Medicinal plants are highly valuable to human livelihood and the medicinal plant wealth of India is well recognized. Studies on possible effects of climate change on medicinal plants are particularly significani due to their value within traditional systems of medicine and as economically useful plants. There is evidence that climate change is causing noticeable ef- fects on life cycles and distribution of the plant species. However, the effects of climate change on secondary metabolites in plants is not well understood. A need for research to improve our understanding of climatic effects on medicinal plants is stressed in the present article. An at- tempt is being made here to review the work so far done on this importanr issue with Indian perspective. Method: Reviews have been collected from different sources related to medicinal plants. Result:The impact of climate change with respect to medicinal plants has been discussed under the following heads. Effect of elevated CO, on productivity and quality, Effect on threars ro me- dicinal plants species, Adaptation rn.ur.rr"l for climate change and global warming, Mitigation measures to reduce emission of CO,/GHGs, Future strategies for research. Conclusion: The impact of climate change on medicinal plants both cultivated and wild is very significant. The need of the hour is to have a focused research approach specially on the accu- mulation of secondary metabolites of health significance.The research on medicinal plants with respect to climate change is very sporadic and insignificant in comparison with other commer- cial crops. It is the high time that, these group of plants should not be left as they are potential sources of bio-molecules and neutraceuticals. 14 ABSTRACTS . 5thWorldAyurvedaCongressandArogyaExpo20l2
  25. 25. Orul Pr"r"ntution l0l2:-r flnical evaluation of bilvadi leha in the management of irritable lbowel syndrome Guepreet Kaur, Dattatrya Nikarn klrose: IBS is a chronic relapsing disorder of gastrointestinal tract' according to Ayurveda it can be correlared with Grahaniroga. Modern Medicine has little to offer in this condition. The lr€sent research work was done to assess the effect of Bilvadi Leha on IBS Severity score, assess 15e effect of Bilvadi Leha on 7HO-QOL BREF score and also to assess the safety of Bilvadi I-eha in patients of IBS. Method: The selection of patients was done from Outdoor and Inpatient wing of P.G. Dept. of KayChikitsa, N.I.A., Arogya Shala, Jaipur and Outdoor wing of Gastroenterology of S.M.S. Hospital, Jaipur. 50 patients were registered for this trial, in which Bilvadi Leha 10 g admin- istered twice daily with lukewarm water after food for 14 weeks. Assessment done on the IBS Severity Score andWHO QOL BREF score. Result: It is seen in the results that there was improvement in chronic abdominal discom-fort or pain, abdominal bloating, constipation, diarrhoea, urgency of bowel movements, feeling of in- complete evacuation and passage of mucus. It is also seen in the results that there was improve- ment in Pravahana, Udara Shula, Anaha, Kapha nihssarana, Mala Durgandha, Udara Atopa, Bhojanoparanta malatyaga and Guda shula. In IBS score percentage of improvement was con- tinuously increasing from 0 to 84th day. Percentage change in the improvement of symptoms from 0 to 16th week was reduced as compared to 84th day i.e. from 60.5% to 3I.6Yo' Conclusion: Bilvadi Leha has shown good recovery in clinical manifestations of the disease showing the amapachana, anulomana, tridoshahara, analgesic, anti-inflammatory activity of Bil- vadi Leha It wa's also well tolerated by all patients. Thus it can be concluded that Bilvadi Leha can be used as safe and important therapeutic agent in the management of IBS. tol:10 Effects of Cinnamomum zeylanicum (Ceylon cinnamon) on blood glu- cose and lipids in a diabetics induced rats PreetiTrivedi Purpose: To evaluate short- and long-term effects of Cinnamomum zeylanicum on food con- sumption, body weight, glycemic control, and lipids in healthy and diabetes-induced rats Method: The study was conducted in two phases (Phase I and Phase II), using Spra-gue-Daw- ley rats in four groups. Phase I evaluated acute effects on fasting blood glucose (FBG) (Groups I and,2) and on post-oral glucose (Groups 3 and 4) blood glucose. Groups 1 and 3 received distilled-water and Groups 2 and 4 received cinnamon-extracts. Phase II evaluated effects on food consumption, body weight, blood glucose, and lipids over I month. Group A (n = 8, distilled-water) and Group B (n = 8, cinnamon-extracts) were healthy rats, while Group C (n = 5, distilled-water) and Group D (n - 5, cinnamon-extracts) were diabetes-induced rats. Serum lipid profile and HbAlc were measured on D-0 and D-30. FBG, 2-h post-prandial blood glu- cose, body weight, and food consumption were measured on every fifth day Result: Phase I: There was no significant difference in serial blood glucose values in cinna- mon-rreated group from time 0 (P > 0.05). Following oral glucose, the cinnamon group dem- Organized by World Ayurveda Foundation and Government of Madhya Pradesh ABSTRACTS 15
  26. 26. Oral Presentation onstrated a faster decline in blood glucose compared to conrrols (P < 0.05). Phase II: Between D0 and D30, the difference in food consumption was shown only in diabetes-induced rats (P < 0.001). Similarly, the significant difference following cinnamon-exrracts in FBG and,2- h post-prandial blood glucose from D0 to D30 was shown only in diabetes-induced rats. In cinnamon-extracts administered groups, total and LDL cholesterol levels were lower on D30 in both healthy and diabetes-induced animals (P < 0.001). Conclusionz C. zeylanicum lowered blood glucose, reduced food intake, and improved lipid parameters in diabetes-induced rats. I O I:I2 Erectile dysfunction (ED) and its trialwith atmaguptadicompound Dipsundar Sahu, Gopalchandra Nanda Purpose: The absence or loss of a healthy sex life can be a devastating experience for an indi- vidual. The inability to have sex due to the failure to start or maintain an erection can mean the lack of personal intimacy and low self-esteem. If the psychological and emotion-al effects of ED cannot be addressed properly, then serious social and interpersonal problems can occur. In this study, the effect of atmaguptadi compound on erectile dysfunction was evaluated. Method: After screening of all the patients through inclusion and exclusion Criteria, 45 pa- tients out of 69 were selected under 3 groups, each group had 15 patienrs. Group-l Trial Drug/ AC 05 grams was administered once in a day at bed time with 120 ml of milk for I month. Group-2- Control drug / Sildenafil Citrate was administered 50 mg once in a day at bed time for 30 days. Group-3 -Placebo/Flour and Semolina powder 5 g was administered once in a day at bed time for 30 days. The ingredients of the formulation are Atmagupta-Mucuna pruriens DC, Goksura-Tribulus terrestris Linn, Asvagandha (lVithania somnifera Dunal), Sweta Gunja (Abrus precatorius Linn), Akarkarabha (Anacyclus pyrethrum DC) and Jatiphaia (Myristica fra- gransHouff). It was administered with tr20 ml of milk with little sugar or honey. All the subjects were initially subjected to counselling. All the subjects were assessed with Rigiscan plus System for objective and subjective evaluation through International Erectile Functions Questionnaire (rEFQ. Result: AC is a herbal compound and having the therapeuric actions of rejuvenation, virili- fication, aphrodisiac, tissue strengthening, sedative, diuretic, anti inflarnmatory, appetiser and anthelmintic effect. AC was a herbal compound having aphrodisiac acrion in ED prob-lem. Conclusion: After close observation of the subjective and objective parameter, it is concluded that AC has significant activity in ED for middle aged male subjects. toHtS Management of stress induced migraine with shankhapushpi and mandookparnee potentiated ashwagandha Vinod Kr.rmar Frrtpo"., Stress induced migraine has become a common but major health issue among new generation.Though not life threatening, it adversely affects the work efficiency as well as self es- teem of the sufferer. A double blind controlled study was done to evaiuate the anti-suess activity of Shankhapushpi and Mandookparnee potentiated Ashwagandha on srress induced migraine. 16 ABSTRACTS . 5th World Ayurveda Congress and Arogya Expo 2012
  27. 27. Oral Presentation lfethod: The drug was used in the dose of 3 grams twice a day in treated group (25 pa-tients) while placebo was given to control group (25 patients).The level of stress was measured mod- erate to severely high on Singh personal Stress source inventory in pre-migraine days in all the patients. Further stress was assessed periodically during the pre-migraine, migraine days and buffer days.The patients were evaluated at the interval of 15 days over the treatment period of 3 months. During the migraine days, Danti-PravalYoga and Shir ShooladiVajra Rasa were used in appropriate doses to terminate the episode of headache. Result: The observations obtained from both groups were analysed. The level of pre-migraine stress was found reduced in treated group very significantly on Singh personal Stress source inventory (pretreatment mean stress score 77.8 + 4.3; post treatment mean stress score 37.5 +4.05) in comparison to control group (pretreatment mean stress score 74.28 + 3.87; post Eeatment mean stress score 67.04 +6.78).The other associated factors sleep quality and pain intensity were also be assessed on visual analog scale. The observations revealed marked im- provement in sleep quality and pain intensity in the pa-tients of treated group in comparison with the control group. Conclusion: The inference of the study was very conclusive to postulate the fact that Shankha- pushpi and Mandookparnee potentiated Ashwagandha controls the stress very effectively and is helpful to manage the stress induced migraine headache. I Ol:18 Anti-obesity activity of Ziziphus mauritiona lam: a potent pancreatic lipase inhibitor Mandavi Deshpande, Sushant Shengule, Kishori Apte I Symbiosis School of Biomed.ical Science.s (SSBS), Symbiosis Internationai {Iniaersity (SIU), Gram: L Purpose: To study anti-obesity activity of Ziziphus mauritiana Lam bark powder (ZMBP) on High Fat Diet (HFD) induced obesity in rats. Method: Obesity was induced in rWistar rats by feeding high fat diet (HFD) for 70 days. The obese rats were distributed in 4 groups (n=5). Group 1: Normal (lean) Control, Group 2: Obese Control, Group 3: Obese rats administered orully 250 mg/kg ZMBP daily, Group 4: Obese rats dosed with 500 mg/kg ZMBP daily, Group 5: Obese rats dosed with Standard Drug Sibutra- mine, 0.90 mg/kg. The rats were dosed orally daily for a period of 90 days. The animals were screened for induction of obesity by analyzing obesity parameters such as Body weight, Anthro- pological Parameters, SerumTryglycerides, Serum Cholesterol, Glucose tolerance test, Insulin resistanceTest, DEXA analysis and MRI Scan. Result: At the end of 90 days treatment with ZMBP the obese rats showed 16.33 % reduc- tion in body weight gain at 250 mglkg and 17.38 % (P<0.05) reduction in body weight gain at 500 mg/kg when compared with the obese control group respectively. The standard drug Sibutramine showed 552% reduction in body weight gain when compared with the obese con- trol group. The DEXA analysis at the end of 90 days of treatment showed 68.99 % (P<0.01) decrease in the Fat mass at25O mg/kg dose and 72.84 % (P<0.001) decrease in the Fat mass at 500 mg/kg dose when compared with the obese control group. The pancreatic lipase activity in250 mg/kg (5.13+0.71 U/mg of protein) and in 500 mg/kg (4.01+0.86I/mg of protein) re- duced significantly (P<0.001) when compared with the obese control group (9.73+2.39 U/mg of protein) Organized by World Ayurveda i:oundation and Government of Madhya Pradesh ABSTRACTS 17
  28. 28. Oral Presentation Conclusion: The ZMBP has anti-obesity activity at 250 mg/kg and 500 mg/kg dose. It has lipase inhibitory activity. lOl,lil Role of pranayama in the improvement of pulmonary health AjaiKumarYadav Purpose: Our life style has entirely changed which includes change in eating habits, mental tension, pollution, use of tobacco, over and above a sedentary life style leading to increase in number of respiratory patients (both obstructive and restrictive disorders). One of the great dilemmas faced by physicians is to treat disease and at the same time to improve the quality of patient's life. Pranayama is the type of self control breathing exercise and very much effective in the improvement of pulmonary health. Method: 25 healthy subjects (age between 20-45 years) were chosen for practicing Pranayama (Bhastrika' Kapalbhati, Anuloma viloma, etc.) lYz hours daily in morning. After the session, subjects took a practice of meditation (Dhyana) and concenrration (Dharana). The study de- signed was of prospective type, the parameters adopted for pulmonary test are PEFR, FVC, FEV1' FEF (FEF25%, FEF5O' recorded before Prdnayama (BASE- 'FEF75o/o,FEF25-75) LINE) and after 3 months of Pranayama. Result: The spirometry was done of all the 25, it was observed that after 3 months of Pranayama all the pulmonary indices were increased significantly (Percentage improvement in pulmonary indices are PEFR= I 4.59'o, FVC= I 3.8 %, FEV1 = I 5 .6yo, FEFZ5Yo=L7 .l%o, FEF50% = 2l .Lyo, FEFT 5 o/o= | 6.6yo, FEF 2 5 -7 5 =2L 6%). . Conclusion: Pranayama brings about cleaning of inner tracrs and desensitisation of the nerve ending, more effective filling and emptying of respiratory apparatus, increase in the power of respiratory muscles, calming effect on mind, and relief from chronic stress pat-tern. Therefore the regular practice of pranayama is helpful in providing better pulmonary health, improves respiratory efficiency and is helpful in prevention and control of obstructive and restrictive re- spiratory disorders. I O l rli-r Management of essential hypertension through takradhara Summiya Javeed, Ravindra Kumar Arahunasi Purpose: Essential Hypertension is prevalent among 970 million people worldwide.7HO rates Essential Hypertension as one of the most important causes of premature deaths in the world population.It is one of the biggest modifiable risk factors for cardiovascular dis-eases and plays a significant role in stroke also. Present day life style modification, stress, anxiety and strain can alter the physiological functioning of our body, it can be prevented and successfully treated if one sticks on to the recommended management plan. According to Ayurveda, present day signs and symptoms of Essential Hypertension can be co-related with "Raktawuta Vata" (Charaka Chikitsa 28, Susrutha Nidana l), in this vitiation of vata, rakta and medha are observed. Allo- pathic management of Essential Hypertension will be continued lifelong, whereas in ayurvedic science as we are treating the karana, the causative factors like stress, anxiety, strain etc, so it can be controlled by Ti*radhara permanently. Thkradhara procedure is anxiolytic, adaptogenic, has tranquiliser effect on body and mind, and also reduces mental stress. Thkra clears the avarana, 18 ABSTRACTS ' 5th World Ayurveda Congress and Arogya Expo 2012
  29. 29. Oral Presentation mols the vata dosha and does kapha chedhana. Hence in this study takradhara procedure has Occn selected for the prevention and control of Essential Hypertension, along with pathya like h salt diet, physical activity and maintaining healthy weight was advised. ffiahod: 30 patients of Essential hlpertension were selected randomly and assigned to a single Etnup, they received takradhara for 7 days, once daily along with pathya. lcsult: In this study for the management of Essential hypertension, according to INC 7th Rule; goal was to attain blood pressure 130/80 mm Hg, which was achieved along with other subjec- nirc parameters showing remarkable results. tQmclusion: In majority of cases observed. Essential hypertension is a major risk factor for cardiovascular diseases, this study was selected and achieved remarkable results with a1'urvedic [Bnagement of takra dhara. rol4ll The prevalence and environmental status of medicinal plants of Bidar District in Karnataka SV Kalmath,SV Kalmath,M S Patil, Kritika 5 K t Karnataka Arts, Science and Commerce College Bidar,2 Saptagiri Science College Bidar Purpose: Convention on Bio-Diversity [CBD] in Earth Summit of Environment and Devel- opment) Rio de Janeiro 1992 resolved for Conservation and Sustainable use of Biodiversity. Over 8000 plant species are used by the different systems of medicine in India. Millions of rural households use medicinal plants in a self-help mode. Over one and a half million practitioners of the Indian Systems of Medicine, in the oral and codified streams use medicinal plants in preven- dve, promotive and curative applications. While demand for the medicinal plants is increasing, their survival in the wild is under threat. Around 1000 species of medicinal plants are facing threat to their exisrence in the wild. Bidar is rich with medicinal plants used by the Traditional Health Practitioner since decades. The objectives of this project is to address their prevalence and ecological status in the wild for the purpose of conservation and sustainable use and also for further scientific investigation of phytochemical analysis for human welfare. Method: General and seasonal wise survey of 131 medicinal plants in the wild in Bidar Dis- trict used by the local health practitioners. Data on geographical, topographical, edaphic and climatic conditions including rainfall, humidity and temperature were col-lected from 1971 to 2011. Population density increased in 4 decades from 151 to 3L2 per sq. km.The impact of population density and the climatic factors on 41 important medicinal plants used by the local health practitioners were studied. Habitat distribution, de-scription, local use for medicine and aesthetic values of each medicinal plant and their survival in wild were studied. l2 health prac- titioners were interviewed, their access to the bio-resource and their experience and knowledge documented and analysed for determining the ecological status of plants. Result: Out of 41 medicinal plants studied 29 were vulnerable, 4 endangered and 8 facing low risk. Conclusion: The causes of the threat to medicinal plants are 1. Habitat destruction and 2. Over utilisation. Organized by World Ayurveda Foundation and Government of Madhya Pradesh ABSTRACTS 19
  30. 30. Oral Presentdtion ror 50 Evaluation of therapeutic efficacy of ayurvedic formulations in pa- tients with alopecia areata Hariharan Subramanian, Dhanvathri Premvel Purpose: Alopecia areata is one among the most prevalent human autoimmune diseases, lead- ing to disfiguring hair loss by the collapse of immune privilege in the hair follicle and subsequent autoimmune attack. Generally, hair loss in patches signifies alopecia areata. It typically presents a gradual or sudden loss of hair in head, eyebrows, eyelashes, nasal, ear and other areas of the body causing patches to appear. Alopecia areata or hair loss occurs in one in 1,000 people. Au- toimmune-associated alopecia areata has no age boundaries and can affect even children, men and women equally. If left untreated, or if the disease does not respond to treatment, complete baldness can resuft in the affected area. The two maior forms of Alopecia are scarring and non scarring. Highlighting the significance, a study was carried out to evaluate the therapeutic ef- ficacy of Ayurvedic formulations in patients with alopecia areata. Method: Fifteen alopecia areata patients of either sex with varying degrees of hair loss were randomly selected for the clinicai trial and were treated with Indralupta Bhasma, Malathyadi Thilam and Guduchi tablet for a period of 3-5 months. Subsequently, most of them were ob- served bi monthly up to a 5 months period' Result: Findings revealed that 8 of the l5 patients with patchy progressive hair loss stabilised and showed no additional hair loss. After 3-5 months of treatment hair growth in these patients were partial or full. Of the other 7 patients with stable patchy total hair loss, four had some lim- ited growth, two patients displayed complete growth of eyebrows and eyelashes, but had poor hair growth on scalp while one patient did not show any response. Conclusion: The study vividly indicated the efficacy of Ayurvedic formulations in patients with Alopecia Areata. The trial medicines too proved to be effective minimizing the patchy hair loss. tol55 Clinical evaluation of herbomineral compound in lumbago w.s.r.to spinal canalstenosis Jai Prakash Singh, Meera Antiwal t Senior Resident, Department of Kayachikitsa, I ME B H U,Varanasi (U P) Purpose: Low back pain or lumbago is a common musculoskeletal disorder affecting 80% of people at some point in their lives. It is a major health care problem. An estimatedT5Yo of all people experience back pain at some time in their lives. There could be multiple causes of low back pain but now a days commonly encountered causes are spinal disc herniation ("slipped disc"), lumbar spinal canal stenosis. Objective of the study was to determine the efficacy of herbo-mineral compound in low back pain (Spinal canal stenosis). . Method: The present study was carried out at I(ayachikitsa O.P.D and I.P.D. of Sir Sunder Lal Hospital, Institute of Medical Sciences, Banaras Hindu University,Varanasi and National insti- tute of Ayurveda Jaipur (Rajasthan) between the period of August 2008 to May 2012. A total of 54 patients of lumbago were registered.The data were analysed with SPSS 16'0 for$7indows. Design: first phase clinical trial (unidirectional) open study, Participant: 54, Main out comes 20 ABSTRACTS ' 5th World Ayurveda Congress and Arogya Expo 2012
  31. 31. Oral Presentation measures: Pain rating scale (VAS), Roland Morris disability score (number of activities impaired by pain),r$flalking time, Strait leg raising test, Safety profile of trial. Result: In this study good improvement (69.0%)), moderate improvement (19.7%), and un- changed or none (LL.3%) was observed. No significant adverse events were observed in this trial. : (Conclusion: This Ayurvedic regimen is extremely effective in reducing pain rating scale (VAS), Roland Morris disability score, walking time and straight leg raising test. lOl i-r6 Evaluation of sedative activity of different solvent extracts of leaves of Celastrus poniculafus Willd llonojit Debnath Purlrose: The leaves of Jyotishmati (Celastrus paniculatus Willd., fam. Celasrraceae) has been recommended for its sedative activity by the tribal pockets of Andaman and Nicobar Islands. However, no pharmacological studies have been yet evaluated its sedative effects.The aim of the present study was to determine the sedative activity of different solvent extracts of the leaves of Jyotishmati. Method: All animals were divided into five different groups (n=6). Group I served as control and ueated with normal saline (5 mVkg, i.p.).Test groups II,III and fV were treated with pet ether, ethyl acetate and methanol extracts respectively. Group V treated with standard drug rhlorpromazine hydrochloride (l mg/kg, i.p.). Pentobarbitone (40 mg/kg, i.p.) was administered after 30 min in Groups (I, II, nI and IV) and after 15 min in Standard groupV. Onset of sleep and duration of sleep were measured for all the groups. Onset of action was recorded by noting the time of loss of reflex for three consecutive trials and duration of sleep recorded by time dif- ference between loss of righting reflex and recovery time. Result: The control group showed quickest recovbry from sleep. All the solvent extracts showed sedative activity. The Pet ether extract (78 min) showed very long duration of sleep with com- parison to the standard drug chlorpromazine hydrochloride (81 min). Conclusion: In the present study the ether soluble extract showed most potent activiry than the other two extracts. The ether extractive seed oil is already proved for its potent sedative action. This may indicate the chemical similarity between the chemical constitu-ents present in the leaf and seed oil also. The steroid, terpenoid present in the pet-ether extract may be responsible for such pharmacological action. Further more study is required for the isolation of the active con- stituent responsible for this activity. lor60 Role of matravasti as rasayana in jarajanya vikar: a clinical study Sathyanarayana Dornala, Om Prakash Sharma t Department of Panchakarma, RDM,$turvedic College & Hospital Purpose:To prove whether Matravasti shows multiple effects on different systems in old people and to substantiate the effects of Matravasti and Rasayana on clinical basis in ageing. Organized by World Ayurveda Foundation and Government of Madhya Pradesh ABSTRACTS 2l
  32. 32. Oral Presentation Method: Eighty two patients - Men of age group 50-80 years; rWomen aged above 45 years or who have attained Menopause and <75 years suffering from common problems of old age irrespective of sex, caste, religion etc. were registered for the study from the OPD of MCD Ay- urvedic Dispensary, Iftishna Nagar, Delhi and OPD and IPD of PG Dept. of Panchakarma, MadhavVilas Hospital,Jaipur. Out of which, 16 patients dropped out did not complete treat- ment. Matravasti was administered for 2l times with Balashwagandha lakshadi (BAL) Thila on alternate days with a dosage 30-80 ml accordingly,After completion of 21 days of Matravasti, all the patients were reviewed for successivd 6 months. All the cases were assessed by consider- ing 15 different aspects reflecting the common problems of ageing like Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL) etc. Result: The overall effect and maximum benefit observed was FAIR (25 %-50 %) in 38 cases out of 66 patients. GOOD response (51 %-75 o/o response) :r;.26 cases and remaining 2 cases Best response (>75%o).And the maximum benefit observed among all the cases is 81.8 % and the least effect was 25 %.Among all clinical parameters considered foi the study maximum ef- ficacy was found in sleep disturbances (67.5%) followed with gait bal-ance deficit (56.25%), emotional status (55.1olo), urinary incontinence (55o/o), Mobility (53.96 %), IADL (51.3%), ADL (50.8olo), constipation (49.5%), cognitive status, (48.78yo), pain (48.14%), dyspnoea (47.25%), hearing impairment (42.5%), visual impairment (41.8%), dermatological manifesta- tions (41 .l7yo), and involuntary movements (22.2%o). Conclusion: Matravasti is a multifaceted and highly effective therapeutic measure in the geri- atric conditions. lorol A clinical evaluation of the effect of devd ali (Lutra echinata) nasya in the management of Hepatitis (Kamala) Meera Antiwal Purpose: Chronic Viral Hepatitis is highly prevalent globally, with some five hundred mil- lion people estimated to be currently infected with Hepatitis B or C. Due to significant global mortality and morbidiry Hepatitis prevention and control programmes are mul-ti-faceted. In Modern Medicine, Chronic Hepatitis B is treated with dt'ugs, including Inter-feron, Nucleoside analogues and other anti-viral agents, whose outqomes are variable and help only some patients. Clinically Jaundice can correlate with Kamala in Ayurveda. But the term Kamala denotes the clinical as well as pathological process rather than a sign or a symptom as in case of Jaundice. Objective of the study is to evaluate the therapeutic efficacy of Devadali Nasya on Kamala (Hepatitis) patients. Method: The patients attending the O.P.D and I.P.D. of the Department of I(ayacikitsa, Sir Sunderlal Hospital, Banaras Hindu University, UP, Varanasi were enrolled in the study, which was conducted from August 2008 to November 201 1. The data were analysed with SPSS 16.0 forWindows. Sample size:60,The test drug - Devadali sheeta Kasaya, Dose and route of Ad- ministration - 4 drops into each nostril consequently thrice at 5 minutes intervals (0 day, 4th day, 15th day), Period of treatment - Fifteen days. All investigations were conducted before first 'therapeutic administration, second therapeutic administration was given on fourth day after the first treatment, and third therapeutic administration was given after fifteen days of first treat- ment. 22 ABSTRACTS . SthWorld Ayurveda Congress and Arogya Expo 2012

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