The document discusses peripheral medical devices in Europe and emphasizes non-invasive approaches. It summarizes a study of over 1700 patients that found various rates of diabetes, peripheral artery disease (PAD), and cardiovascular issues among men and women. The document advocates for programs focused on early detection, monitoring, and initiating non-invasive therapies to minimize surgeries and avoid amputations by achieving over 90% sensitivity and specificity. Telemedicine can effectively monitor patients and pharmacodynamic effects of medications while enabling application of therapies. An example from Brazil showed success in detection and management of at-risk patients. The conclusion emphasizes that telemedicine enables early detection and monitoring for prevention with an integrated medical approach.