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GOUT-NURAINI ENSIU (PHY001171010)
ALZHEIMER DISEASE-UMI HABIBAH
SUAIB (PHY001121010)
   Gout, a disease long known through history
    as "The Disease of Kings" or the "Rich
    Man's disease", is a severely painful
    condition caused from too much uric
    acid (monosodium urate) in the body.
1-Gout happens when the excess uric acid in the
  blood crystallizes into needle-like shapes within
  the synovial fluid.

2-The immune system tries to purge the foreign
  objects when they sensing that the uric acid
  crystals do not belong in the synovial fluids.
3-The immune system attacking the uric acid
  causes swelling to occur.

4-As this swelling worsens, painful arthritis
  develops within the afflicted joint. This arthritis
  causes almost unbearable pain.
Stage 1 ( Asymptomatic )
 During the first stage,the patients develop
  hyperuricemia ( urate levels rise but do not
  produce symptoms )..



  Hyperuricemia---> abnormally high amount
  of uric acid in the blood stream.
Stage 2 (acute)
 During this stage, patient experiences
  painful swelling and tenderness. Symptom
  usually lead the patient to seek medical
  attention.
Stage 3 ( intercitical )
 The third stage, the intercritical stage may
  last for months to years. The patient may be
  asymptomatic or experience exacerbations.
Stage 4 ( chronic )
 Chronic stage is gout is charaterized by
  tophi, large masses of urates within the
  subarticular bone or surrounding soft
  tissues. Less commonly, tophi form in the
  internal organs.Tophi deposists precipate
  joint erosion and tendon rupture
   A tendency towards gout can be hereditary.
   I t can begin as a result of joint
    injury, surgery, chemotherapy or even
    losing weight rapidly on a crash diet.
   However, the main causes are fatty red
    meats, certain seafood and all alcohol.
   Severe pain in the joints.
   Itchy and peeling skin later.
   Redness and inflammation.
   Red/purplish skin.
   Fever .
   Less flexibility .
   Nodules.
SELF CARE AT HOME
 Take medications as prescribed.



   While a joint is hot and swollen, you may want to use a
    cane or similar support to keep your weight off that
    joint.

   It may be helpful to keep the swollen joint elevated
    above your chest as much as possible.

   Ice packs can be helpful in relieving pain and reducing
    inflammation.
   Maintaining adequate hydration is key for
    minimizing the frequency and intensity of
    attacks.

   Cherry juice may decrease the intensity and
    severity of attacks.
Stretching and flexibility Exercises
Aim:
 Reduce stiffness.

 Increase circulation.

 To help strengthen the muscle.



  Example:Performing simple stretches, such as
  knee bends, helps relieve tension in the joints
  and reduce inflammation.Yoga.Taichi.
Endurance Program
Aim:
 Improve blood circulation, heart function and
  relieve symptoms of gout.
 Because gout often attacks your feet, it's
  important to engage in low-impact exercises
  that won't put any additional strain on your
  lower extremities. Physical therapy will include
  a swimming or stationary cycling program.
   Use medications that help you excrete uric
    acid (a class of drugs known as uricosuric
    agents)
   Use medications that help you decrease the
    production of urate (e.g., Allopurinol)
   Lose weight slowly. (Fast weight loss tends
    to cause further attacks.)
   Diet Changes. This means avoiding increasing
    fluid intake and avoiding:
       Alcohol (especially red wine and beer)
       Meats, poultry, fish and seafood.
       Fatty foods
       Certain vegetables--
        asparagus, cauliflower, beans, peas, mushrooms and
        spinach
   Protect the joint from further trauma by wearing
    loose shoes, and avoiding occupations that are
    hard on the feet.
   Follow up regularly with your physician. After their
    first attack, patients should be seen every couple
    months for a year and then every 6 months.
o   Alzheimer's is a type of dementia that causes
    problems with memory, thinking and
    behavior. Symptoms usually develop slowly
    and get worse over time, becoming severe
    enough to interfere with daily tasks.
o   AD begins slowly
o   AD usually begins after age 60
o   The cause of Alzheimer’s disease is
    unknown, but there are factors are thought to
    contribute:
   Viral factor such as slow-growing CNS viruses
   Trauma
   Genetic factors
   Memory loss that disrupts daily life
   Confusion with time or place
   Trouble understanding visual image and
    spatial relationship
   New problem with word in speaking or
    writing
   Withdrawal from work or social activity
   Difficulty having a conversation
   Difficulty manage a budget
   Stage 1
    No impairment (normal function)


   Stage 2
    Very mild cognitive decline (may be normal
    age-related changes or earliest signs of
    Alzheimer's disease)
   Stage 3
    Mild cognitive decline (early-stage
    Alzheimer's can be diagnosed in some, but
    not all, individuals with these symptoms)
   Stage 4
    Moderate cognitive decline
    (Mild or early-stage Alzheimer's disease)
   Stage 5
    Moderately severe cognitive decline
    (Moderate or mid-stage Alzheimer's disease)
   Stage 6
    Severe cognitive decline
    (Moderately severe or mid-stage Alzheimer's
    disease)
   Stage 7
    Very severe cognitive decline
    (Severe or late-stage Alzheimer's disease)
   Age
   Family history
   Sex
   Gender
   Genetic
   Eating a well-balanced and healthy diet
   Avoiding smoking and excess alcohol
   Maintaining your weight
   Keeping your cholesterol and blood pressure
    levels in check
   Exercising regularly
   Getting regular sleep
   Maintaining a social network
   Stimulating your brain by doing the
    crossword, taking dance lessons, or learning a new
    language
   Protecting your brain by wearing a helmet when
    you bike
   Balance exercise
   Strengthening exercise
   Stretching exercise
   Endurance exercise
  Medication
-aricept,cognex,exelon,rezadyne
Gout and alzheimer disease

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Gout and alzheimer disease

  • 1. GOUT-NURAINI ENSIU (PHY001171010) ALZHEIMER DISEASE-UMI HABIBAH SUAIB (PHY001121010)
  • 2. Gout, a disease long known through history as "The Disease of Kings" or the "Rich Man's disease", is a severely painful condition caused from too much uric acid (monosodium urate) in the body.
  • 3.
  • 4. 1-Gout happens when the excess uric acid in the blood crystallizes into needle-like shapes within the synovial fluid. 2-The immune system tries to purge the foreign objects when they sensing that the uric acid crystals do not belong in the synovial fluids.
  • 5.
  • 6. 3-The immune system attacking the uric acid causes swelling to occur. 4-As this swelling worsens, painful arthritis develops within the afflicted joint. This arthritis causes almost unbearable pain.
  • 7. Stage 1 ( Asymptomatic )  During the first stage,the patients develop hyperuricemia ( urate levels rise but do not produce symptoms ).. Hyperuricemia---> abnormally high amount of uric acid in the blood stream.
  • 8. Stage 2 (acute)  During this stage, patient experiences painful swelling and tenderness. Symptom usually lead the patient to seek medical attention.
  • 9. Stage 3 ( intercitical )  The third stage, the intercritical stage may last for months to years. The patient may be asymptomatic or experience exacerbations.
  • 10. Stage 4 ( chronic )  Chronic stage is gout is charaterized by tophi, large masses of urates within the subarticular bone or surrounding soft tissues. Less commonly, tophi form in the internal organs.Tophi deposists precipate joint erosion and tendon rupture
  • 11.
  • 12.
  • 13.
  • 14.
  • 15. A tendency towards gout can be hereditary.  I t can begin as a result of joint injury, surgery, chemotherapy or even losing weight rapidly on a crash diet.  However, the main causes are fatty red meats, certain seafood and all alcohol.
  • 16. Severe pain in the joints.  Itchy and peeling skin later.  Redness and inflammation.  Red/purplish skin.  Fever .  Less flexibility .  Nodules.
  • 17. SELF CARE AT HOME  Take medications as prescribed.  While a joint is hot and swollen, you may want to use a cane or similar support to keep your weight off that joint.  It may be helpful to keep the swollen joint elevated above your chest as much as possible.  Ice packs can be helpful in relieving pain and reducing inflammation.
  • 18. Maintaining adequate hydration is key for minimizing the frequency and intensity of attacks.  Cherry juice may decrease the intensity and severity of attacks.
  • 19.
  • 20. Stretching and flexibility Exercises Aim:  Reduce stiffness.  Increase circulation.  To help strengthen the muscle. Example:Performing simple stretches, such as knee bends, helps relieve tension in the joints and reduce inflammation.Yoga.Taichi.
  • 21. Endurance Program Aim:  Improve blood circulation, heart function and relieve symptoms of gout.  Because gout often attacks your feet, it's important to engage in low-impact exercises that won't put any additional strain on your lower extremities. Physical therapy will include a swimming or stationary cycling program.
  • 22. Use medications that help you excrete uric acid (a class of drugs known as uricosuric agents)  Use medications that help you decrease the production of urate (e.g., Allopurinol)  Lose weight slowly. (Fast weight loss tends to cause further attacks.)
  • 23. Diet Changes. This means avoiding increasing fluid intake and avoiding:  Alcohol (especially red wine and beer)  Meats, poultry, fish and seafood.  Fatty foods  Certain vegetables-- asparagus, cauliflower, beans, peas, mushrooms and spinach  Protect the joint from further trauma by wearing loose shoes, and avoiding occupations that are hard on the feet.  Follow up regularly with your physician. After their first attack, patients should be seen every couple months for a year and then every 6 months.
  • 24.
  • 25. o Alzheimer's is a type of dementia that causes problems with memory, thinking and behavior. Symptoms usually develop slowly and get worse over time, becoming severe enough to interfere with daily tasks. o AD begins slowly o AD usually begins after age 60
  • 26. o The cause of Alzheimer’s disease is unknown, but there are factors are thought to contribute:  Viral factor such as slow-growing CNS viruses  Trauma  Genetic factors
  • 27. Memory loss that disrupts daily life  Confusion with time or place  Trouble understanding visual image and spatial relationship  New problem with word in speaking or writing  Withdrawal from work or social activity  Difficulty having a conversation  Difficulty manage a budget
  • 28. Stage 1 No impairment (normal function)  Stage 2 Very mild cognitive decline (may be normal age-related changes or earliest signs of Alzheimer's disease)
  • 29. Stage 3 Mild cognitive decline (early-stage Alzheimer's can be diagnosed in some, but not all, individuals with these symptoms)  Stage 4 Moderate cognitive decline (Mild or early-stage Alzheimer's disease)
  • 30. Stage 5 Moderately severe cognitive decline (Moderate or mid-stage Alzheimer's disease)  Stage 6 Severe cognitive decline (Moderately severe or mid-stage Alzheimer's disease)  Stage 7 Very severe cognitive decline (Severe or late-stage Alzheimer's disease)
  • 31. Age  Family history  Sex  Gender  Genetic
  • 32. Eating a well-balanced and healthy diet  Avoiding smoking and excess alcohol  Maintaining your weight  Keeping your cholesterol and blood pressure levels in check  Exercising regularly  Getting regular sleep  Maintaining a social network  Stimulating your brain by doing the crossword, taking dance lessons, or learning a new language  Protecting your brain by wearing a helmet when you bike
  • 33. Balance exercise  Strengthening exercise  Stretching exercise  Endurance exercise