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Asthma management guidelines and pharmacotherapy have evolved in parallel as new products have been developed. The introduction of ICS in 1972 led to the need to categorise medicines as either controllers or relievers; however, this did not happen until more than 20 years later. The introduction of the long-acting bronchodilator, formoterol, has led to some difficulties in classification as it is both a long-acting (controller) medication and a rapid-acting (reliever) medication. The addition of a long-acting 2 -agonist to a low dose of ICS has been shown to provide better asthma control than a higher dose of ICS alone. The introduction of the first combination product, Seretide ™ , was a combination of two controller medications: salmeterol and fluticasone. Symbicort ® , which contains both budesonide and formoterol, is a combination product containing both controller and potential reliever medications.