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Linda Hope
Senior Industry Specialist
Edgewater Fullscope
Potency Management
* APICS Dictionary (American Production and Inventory Control Society)
Active

Standard Potency
% Caustic

.

As less Quantity is
needed, more
Compensating
Quantity is required

As Potency
incr...
Active

Standard Potency
% Caustic

.

As more Quantity is
needed, less
Compensating
Quantity is required

As Potency
decr...
Standard Potency
% Fatty Acid

Active

Compensating

OliveOil

As Potency
decreases, more
Quantity of the Active
Ingredien...
Standard Potency
% Fatty Acid

Active

Compensating

OliveOil

As Potency
increases, less
Quantity of the Active
Ingredien...
Filler

Active

Compensating

Compensatio
n Principle
Complimentary
Effect

Compensating

Opposing
Effect
A batch of lower concentration (42.5%) has been selected
which results in a increased required quantity for the Active
ing...
A batch of lower concentration (42.5%) has been selected
which results in a increased required quantity for the Active
ing...
Pay Suppliers and value inventory based on the active ingredient quantity received.
Most common price calculation:
Price /...





•

•

•
Batch Order Sequencing
Batch Order Sequencing
•

–
–
–
–
Batch Order Sequencing
From this…

To This…
Flavor – Pack Size - Tablet Size

Cleanup!
Simple Sequencing : Flavor

Grape
Banana

Orange

Minimizes Changeover
And Cleanups

Lemon
Chocolate
Safe Sequencing : Drugs

Ensure different products that
look similar are never sequenced
to follow each other
Using multiple sequences ranked within a sequence
group provides the desired sequence

Sequence 1: Flavor
Sequence 2: Pack...
Lot Inheritance
•
•
•
Co-Product A
Batch Attributes
Appearance white crystalline substance
Melting point app. 65°C
Solubility in water 680 g/l (...
Cell Culture 1
Blood Type: O +
Cell Culture 2
Blood Type: O +
Cell Culture 3
Blood Type: O +

Cell Culture 4
Blood Type: O...
Example: Assembly

Expiry Date:
12/17/2012
Expiry Date:
12/21/2012

Expiry Date:
12/19/2012
Assembly
Components

Assembly ...
Example: Consumed inventory lots include these
attributes and shelf life
Shelf Life: Earliest Expiration date is 04/01/201...
Example: Batch for the formula item includes the batch
attributes and shelf life dates of the consumed raw
material batche...
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
5 Manufacturing R2 Enhancements Life S
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5 Manufacturing R2 Enhancements Life S

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5 Manufacturing R2 Enhancements Life S

  1. 1. Linda Hope Senior Industry Specialist Edgewater Fullscope
  2. 2. Potency Management
  3. 3. * APICS Dictionary (American Production and Inventory Control Society)
  4. 4. Active Standard Potency % Caustic . As less Quantity is needed, more Compensating Quantity is required As Potency increases, less Quantity of the Active Ingredient is required Sodium Hydroxide Potassium Hydroxide C Compensating
  5. 5. Active Standard Potency % Caustic . As more Quantity is needed, less Compensating Quantity is required As Potency decreases, more Quantity of the Active Ingredient is required Sodium Hydroxide Potassium Hydroxide C Compensating
  6. 6. Standard Potency % Fatty Acid Active Compensating OliveOil As Potency decreases, more Quantity of the Active Ingredient is required As more Quantity is needed, more Compensating Quantity is required
  7. 7. Standard Potency % Fatty Acid Active Compensating OliveOil As Potency increases, less Quantity of the Active Ingredient is required As less Quantity is needed, less Compensating Quantity is required
  8. 8. Filler Active Compensating Compensatio n Principle Complimentary Effect Compensating Opposing Effect
  9. 9. A batch of lower concentration (42.5%) has been selected which results in a increased required quantity for the Active ingredient. When the Balance batch ingredients is clicked, the Balanced quantity for the Compensating, Filler and other ingredients are calculated.
  10. 10. A batch of lower concentration (42.5%) has been selected which results in a increased required quantity for the Active ingredient. When the Balance batch ingredients is clicked, the Balanced quantity for the Compensating, Filler and other ingredients are calculated.
  11. 11. Pay Suppliers and value inventory based on the active ingredient quantity received. Most common price calculation: Price / Target Potency * Actual Potency received 50 Gallons 85% Active = $655.50 50 Gallons 82.5% Active = $636.22 50 Gallons 86.7% Active = $668.61 Price calculation may vary by supplier and item
  12. 12.    
  13. 13. • • •
  14. 14. Batch Order Sequencing
  15. 15. Batch Order Sequencing • – – – –
  16. 16. Batch Order Sequencing From this… To This… Flavor – Pack Size - Tablet Size Cleanup!
  17. 17. Simple Sequencing : Flavor Grape Banana Orange Minimizes Changeover And Cleanups Lemon Chocolate
  18. 18. Safe Sequencing : Drugs Ensure different products that look similar are never sequenced to follow each other
  19. 19. Using multiple sequences ranked within a sequence group provides the desired sequence Sequence 1: Flavor Sequence 2: Pack Type
  20. 20. Lot Inheritance
  21. 21. • • •
  22. 22. Co-Product A Batch Attributes Appearance white crystalline substance Melting point app. 65°C Solubility in water 680 g/l (20°C 1400 g/l (60°C) Alkaline resistance good Acid resistance decomposition Odour slight internal odour Delivery form powder, granules HS-Code 28 31 10 00 Chemical 123 Batch Attributes Appearance white crystalline substance Melting point app. 65°C Solubility in water 680 g/l (20°C 1400 g/l (60°C) Alkaline resistance good Acid resistance decomposition Odour slight internal odour Delivery form powder, granules HS-Code 28 31 10 00 Co-Product B Batch Attributes Appearance white crystalline substance Melting point app. 65°C Solubility in water 680 g/l (20°C 1400 g/l (60°C) Alkaline resistance good Acid resistance decomposition Odour slight internal odour Delivery form powder, granules HS-Code 28 31 10 00
  23. 23. Cell Culture 1 Blood Type: O + Cell Culture 2 Blood Type: O + Cell Culture 3 Blood Type: O + Cell Culture 4 Blood Type: O + Human Skin Tissue Blood Type: O +
  24. 24. Example: Assembly Expiry Date: 12/17/2012 Expiry Date: 12/21/2012 Expiry Date: 12/19/2012 Assembly Components Assembly will inherit the earliest shelf life of 12/17/2012
  25. 25. Example: Consumed inventory lots include these attributes and shelf life Shelf Life: Earliest Expiration date is 04/01/2013 Attribute Values: Unique attributes and values for each item and batch
  26. 26. Example: Batch for the formula item includes the batch attributes and shelf life dates of the consumed raw material batches Inherits earliest expiry date for consumed batches Inherits attributes of consumed lots and their respective values

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