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Nigella sativa is a safe herbal product

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Nigella sativa is a safe herbal product

  1. 1. ● Letter to the Editor Nigella sativa is a safe herbal product Abdullah Bamosa Department of Physiology, College of Medicine, University of Dammam, Dammam, Saudi Arabia KEYWORDS: Nigella sativa; diabetes mellitus, type 2; kidney failure, acute DOI: 10.3736/jintegrmed2014007 Bamosa A. Nigella sativa is a safe herbal product. J Integr Med. 2014 January; Epub ahead of print. Received December 28, 2013; accepted December 31, 2013. Open-access article copyright © 2014 Abdullah Bamosa. Correspondence: Abdullah Bamosa, PhD, Associate Professor; E-mail: This is a comment on the following article: Arslan E, Sayın S, Demirbaş Ş, Çakar M, Somak NG, Yeşilkaya Ş, Sağlam K. A case study report of acute renal failure associated with Nigella sativa in a diabetic patient. J Integr Med. 2013; 11(1): 64-66. We are currently publishing results on one-year N. sativa treatment in diabetic patients. It showed that N. sativa has hypoglycemic, hypolipidemic and cardioprotective effects with no adverse effects. Competing interests We have been conducting research on the beneficial effects of Nigella sativa for more than 15 years. We have conducted several clinical trials and used up to 3 g/d and found no toxic effect, rather N. sativa had positive effects on these patients. N. sativa in three doses (1, 2, and 3 g/d) with 40 mg nexium produced from 50% to 67% eradication of Helicobacter pylori in non-ulcer dyspeptic patients[1]. Furthermore, N. sativa in type 2 diabetic patients with the same doses (1, 2 and 3 g/d) reduced fasting blood glucose and hemoglobin A1c significantly by the end of the three months treatment and all basic indexes were normal[2]. I really think that the investigators[3] should have looked at the composition of the tablets they reported that cause acute renal failure before they attributed this effect to N. sativa. Many herbal products sold in public shops are contaminated with other products that could be sometimes toxic. I would not agree with the conclusion of the investigators and I think their approach should have been more scientific before jumping into such a conclusion. The author declares that he has no competing interests. REFERENCES 1 2 3 Salem EM, Yar T, Bamosa AO, Al-Quorain A, Yasawy MI, Alsulaiman RM, Randhawa MA. Comparative study of Nigella sativa and triple therapy in eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. Saudi J Gastroenterol. 2010; 16(3): 207-214. Bamosa AO, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A. Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus. Indian J Physiol Pharmacol. 2010; 54(4): 344-354. Arslan E, Sayın S, Demirbaş Ş, Çakar M, Somak NG, Yeşilkaya Ş, Sağlam K. A case study report of acute renal failure associated with Nigella sativa in a diabetic patient. J Integr Med. 2013; 11(1): 64-66. Submission Guide Journal of Integrative Medicine (JIM) is a PubMed-indexed, peer-reviewed, open-access journal, publishing papers on all aspects of integrative medicine, such as acupuncture and traditional Chinese medicine, Ayurvedic medicine, herbal medicine, homeopathy, nutrition, chiropractic, mind-body medicine, Taichi, Qigong, meditation, and any other modalities of complementary and alternative medicine (CAM). Article ● No submission and page charges types include reviews, systematic reviews and meta-analyses, randomized controlled and pragmatic trials, translational and patient-centered effectiveness outcome studies, case series and reports, clinical trial protocols, preclinical and basic science studies, papers on methodology and CAM history or education, editorials, global views, commentaries, short communications, book reviews, conference proceedings, and letters to the editor. ● Quick decision and online first publication For information on manuscript preparation and submission, please visit JIM website. Send your postal address by e-mail to, we will send you a complimentary print issue upon receipt. Editors-in-Chief: Wei-kang Zhao & Lixing Lao. ISSN 2095-4964. Published by Science Press, China. Journal of Integrative Medicine 1 Epub ahead of print