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CloudBurst: Highly Sensitive Read Mapping with MapReduce Michael Schatz May 27,  2009 AWS Start-Up Event
Searching Wikipedia ,[object Object],[object Object],[object Object],[object Object],[object Object],Michael Schatz Michel Schatz Michal Schatz … Michael Shatz Michael Schats Michael Schantz
Indexing with MapReduce ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Apple Zebra Apples are the fruit of the apple tree with black seeds. Zebras are equids with black and white stripes. … Apples 1 Apple 7 And 6 Are 2 , 2 Black 10 ,5 Equids 3 Fruit 4 Of 5 Seeds 11 Stripes 8 The 3 , 6 Tree 8 White 7 With 9 ,4 Zebras 1
Indexing DNA with MapReduce ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Chr 1 Chr X CATGCTGCGAATA TATGAATTCC … AAT 10 ,5 ATA 11 ATG 2 , 2 ATT 6 CAT 1 CGA 8 CTG 5 GAA 9 ,4 GCG 7 GCT 4 TAT 1 TCC 8 TGA 3 TGC 3 , 6 TTC 7
Personal Genomics ,[object Object],Heart Disease Cancer Loves Portuguese Water Dogs
CloudBurst Architecture ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Human chromosome 1 Read 1 Read 2 map shuffle … … reduce Read 1, Chromosome 1, 12345-12365 Read 2, Chromosome 1, 12350-12370
[object Object],[object Object],[object Object],[object Object],[object Object],Amazon EC2 Evaluation
Grand Challenge of Biology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acknowledgements Mihai Pop Ben Langmead Jimmy Lin Steven Salzberg
Thank You!

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