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Dr. Amita Jain

Consultant
Urogynaecologist
Medanta Institute of Kidney & Urology
Medanta -The Medicity
Gurgaon, Haryana -122001, INDIA


Female Genital Fistula(FGF) is a socially debilitating
problem with important medicolegal implications.



In the developing nations, nearly 5 million women
annually suffer severe morbidity with obstetric
fistulae being the foremost on the list. (WHO 1991)



Around > 2 million women living with fistula, with
approximately 50,000 to 100,000 cases occurring
annually, mostly in Africa, Asia, and the Arab world.
Stanton C et al, Int J Gynaecol Obstet 2007, 99:S4-S9.



The unmet need for fistula repair is estimated to be
as high as 99%. Ahmed S et al, Int J Gynaecol Obstet 2007, 99:S1-S3.
DR AMITA JAIN
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use of this material without prior permission is strictly prohibited
DR AMITA JAIN
Confidential & Proprietary.
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use of this material without prior permission is strictly prohibited
• 74 years
• C/O Involuntary leakage of urine with coughing, sneezing
& change in posture
• Co - morbidities
Old age (Postmenopausal)
Past multiple surgeries
- Wertheim’s hysterectomy followed by Radiotherapy –
carcinoma cervix 1986
- Laparotomy - intestinal obstruction 1990
- Repeated urethral dilatation - retention of urine 2008
- Abdominal Sacrocolpopexy - vaginal vault prolapse
March 2010
Hypertension
Hypothyroidism
Osteoarthritis

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General & Neurological Examination: normal
POPQ
Aa
+2.0
Gh
7
Ap
-3

Ba
+1.0
Pb
3.5
Bp
-3

C
-5
TVL
7
D
0

STAGE III CYSTOCELE

Urethral Hypermobility +
Stress leak +

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SENSATION RESULTS

LEAK POINT PRESSURES

SENSATION

Bladder
filling

First Sensation

110 cc

10 cmH2O

Strong Desire

280 cc

11 cmH2O

Max Cyst
Capacity

280 cc

15 cmH2O

Bladder filling

Pabd

Pdet

1

156 cc

13 cmH2O

10 cmH2O

2

248 cc

10 cmH2O

7 cmH2O

3

276 cc

10 cmH2O

11 cmH2O

Pdet

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Total bladder capacity

281cc

Peak flow rate

7ml/s

Pdet at peak flow

15 cmH2O

Average flow rate

3 ml/s

Residual Urine

0 ml

Opening Pdet

9 cmH O

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Braided Suture
Piercing
bladder wall

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DR AMITA JAIN
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Blind pit at Ant. Vaginal
wall ( ? healed fistula
opening)

Negative Three
Swab Test
Suture Removal
3 weeks

Cystocele Repair
&
Midurethral Sling Placement
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Peak Flow Rate

15 ml/s

Average Flow Rate

7 ml/s

Voided Volume

267 ml

Voided Time

24 s

Flow Time

24 s

Post Void Residual

150 cc

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•

Able to hold & void herself

•

Fully continent ( Pads not required)

•

Clean Intermittent Self Catheterisation
(3 times a day)

 

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• 54 years
• Recurrent UTI
• On & off pinkish foul smelling vaginal
discharge

1.5 yrs

• Past Surgical History
- Lap Hysterectomy 2 yrs back (Menorrhagia cause ? fibroid
uterus)
- Cholecystectomy 20 yrs back
- Incisional hernia repair 16 yrs back

• Co-morbidities
- Hypertension 3-4 months

- Diabetes Mellitus 3-4 months
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Per speculum:
- Black colored material at the apex of
vaginal vault
- Foul smelling black to brown dirty
discharge soiling the walls of vaginal vault

DR AMITA JAIN
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Impression:
Low
Rectovaginal
fistula

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A black colored
? Suture at the
apex of vaginal
vault

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On removal – black brown colored infected material
drained.
 Communicating path traced through a probe.


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Abdominal Repair

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Vaginal
opening
traced

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No communicating
path into sigmoid
colon or rectum
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Edges of
Vaginal
opening
freshened up
& closed

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 No

foul smell discharge

 Not

a single episode of UTI

 
DR AMITA JAIN
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DR AMITA JAIN
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•
•
•
•

54 years
Pain in left loin – 1 month
Continuous urinary leakage – 1 month
H/O present illness

month

- D & C for menorrhagia 4 months back.
- f/b Vaginal hysterectomy with left oophorectomy after one

- C/O continuous significant vaginal bleeding in postop
- re-evaluated after 2 weeks & some stiches were put through
vaginal route
- developed high grade fever after 2 days f/b urinary
incontinence

• Past H/O
- Tubal ligation 30 yrs back
• No Co - morbidities

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Findings:
Moderate Left sided
Hydroureteronephrosis with
dilatation of left ureter in its entire
extent with abrupt cut off at distal
end, which appears to merge with
vaginal stump

DR AMITA JAIN
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DR AMITA JAIN
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DR AMITA JAIN Confidential &
Proprietary.
Any use of this
material without prior permission is
strictly prohibited
DR AMITA JAIN
Confidential & Proprietary.
Any
use of this material without prior permission is strictly prohibited
DR AMITA JAIN Confidential &
Proprietary.
Any use of this
material without prior permission is
strictly prohibited
DR AMITA JAIN
Confidential & Proprietary.
Any
use of this material without prior permission is strictly prohibited
DR AMITA JAIN Confidential &
Proprietary.
Any use of this
material without prior permission is
strictly prohibited
Abrupt cut off at 2 cm
distance from left ureteric
orifice

DR AMITA JAIN
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Post Hysterectomy
Iatrogenic Left Ureteric
Trauma with Vesico-vaginal
fistula

DR AMITA JAIN
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Left Percutaneous Nephrostomy
4 weeks
Cystoscopy + O’Conner’s VVF Repair* + Left Ureteric
Reimplantation (stented)
[ discharged on POD 5 with SPC in situ]
“The best approach for complex fistulas is transabdominal using the
O'Connors bivalve technique.” O'Connor VJ et al. Suprapubic closure of vesicovaginal
fistula. J Urol. 1973;109:51–4.
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At 2 Weeks

Findings:
•Well maintained
bladder outline
•No leak
DJ Stent removal
done

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

Normal KFT



Normal findings of DTPA Scan and
USG Whole Abdomen

 
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DR AMITA JAIN
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• 31 years
• Continuous urinary leakage per vaginum for 2 year

• Past Surgical History
- MTP with tubal ligation (continous leakage in postop)
- Hysterectomy with reimplantation of right ureter
- Cystoscopy (0.5 cm sized fistula inferomedial to left
ureteric orifice, right ureteric orifice not seen) + LRGP + LDJS
- 2 failed attempts of vaginal repair of VVF
- LRGP + Left Laser endoureterotomy + Laser fulgration
of VVF

• No Co-morbidities
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

USG KUB: B/L Chronic Renal Parenchymal Disease



KFT: Bld Urea 93 mg/dl
S. Creatinine 4.76 mg/dl



Hb 8 g/dl



Urine C/S: E Coli >10 cfu/ml

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DR AMITA JAIN
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Impression:

B/L contracted Kidneys,
Re-implantation of right ureter ? into
bowel (dilated 8 mm),
DJ Stent on left side,
4 mm sized focal defect in posterior
wall of UB communcating to vaginal
stump (fluid in endovaginal canal)
Renal Transplantation after
Fistula Repair

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DR AMITA JAIN
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• 52 years
• Continuous urinary leakage per vaginum for 2 year
• Large bed sore over sacrum

• Past History

- Received multiple courses of chemoradiation for Ca
Cervix (grade III) diagnosed in 1999
- Multiple cystoscopies for gross hematuria in 2009
- Cystoscopic fulgration & angioembolisation in Aug
2009
- Admitted in ICU for septicemia - on catheter removal
at discharge noticed continuous leakage of urine

• No Co-morbidities
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 Left

small sized kidney

 Right

normal sized kidney

 No

Ureterovaginal fistula/ no
ureteric stricture

DR AMITA JAIN
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use of this material without prior permission is strictly prohibited
 Frozen
 Large

Pelvis

Vesico-vaginal fistula

DR AMITA JAIN
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use of this material without prior permission is strictly prohibited


Small capacity bladder



Fluffy tissue inside



Patchy inflammation



Supratrigonal large irregular hole at
left side of posterior wall

DR AMITA JAIN
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use of this material without prior permission is strictly prohibited
Urinary Diversion
( Transverse Colonic Urinary Conduit)

DR AMITA JAIN
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use of this material without prior permission is strictly prohibited
POD3
 Myelosuppresion with pancytopenic sepsis
 B/L Parotitis with right parotid abscess
 Respiratory failure with Metabolic Acidosis
 Acute Renal Failure with Dyselectrolytemia
 Liver Dysfunction with Hypoalbuminemia
 Paralytic ileus
POD 11
 Anastomotic leakage
Conservative Management in ICU by Multidisciplinary Team
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

Went home on full recovery after 6 weeks



Doing well at 2years 6 months

 

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use of this material without prior permission is strictly prohibited


Obstretical fistulas are associated with high
incidence of recurrence and failure rates due to
their large size and presence of ischaemic
tissues. Arrow SS et al, Obstet Gynecol Surv. 1996;51:568–74.



Postsurgical fistulas are result of more direct
and localised trauma to otherwise healthy
tissue, so having better results after repair. Hadley
HR. Vesicovaginal fistula. Curr Urol Rep. 2002;3:401–7.

DR AMITA JAIN
Confidential & Proprietary.
Any
use of this material without prior permission is strictly prohibited


To date improvements in health care facilities may
have led to change in etiological aspect of FGF.



Surgical correction is still a great challenge and
requires a team approach for better results.

“Prevention is better than cure".
THANKS
DR AMITA JAIN
Confidential & Proprietary.
Any
use of this material without prior permission is strictly prohibited
Medanta Institute of Kidney & Urology

Dr. Amita Jain
Urogynaecology Clinic
12th Floor, OPD Wing,
Medanta -The Medicity
Gurgaon, Haryana -122001, INDIA
Tel: +91 124 4141 414 info@medanta.org www.medanta.org
MOB. +91-9871136110
http://www.urogynecologistindia.in/
http://amitajainurogynaecolgist.blogspot.in/
http://www.linkedin.com/mbox?displayMBoxItem=&itemID=I225857003_75

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Dr Amita Jain Treats Complex Fistulas

  • 1. Dr. Amita Jain Consultant Urogynaecologist Medanta Institute of Kidney & Urology Medanta -The Medicity Gurgaon, Haryana -122001, INDIA
  • 2.  Female Genital Fistula(FGF) is a socially debilitating problem with important medicolegal implications.  In the developing nations, nearly 5 million women annually suffer severe morbidity with obstetric fistulae being the foremost on the list. (WHO 1991)  Around > 2 million women living with fistula, with approximately 50,000 to 100,000 cases occurring annually, mostly in Africa, Asia, and the Arab world. Stanton C et al, Int J Gynaecol Obstet 2007, 99:S4-S9.  The unmet need for fistula repair is estimated to be as high as 99%. Ahmed S et al, Int J Gynaecol Obstet 2007, 99:S1-S3. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 3. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 4. • 74 years • C/O Involuntary leakage of urine with coughing, sneezing & change in posture • Co - morbidities Old age (Postmenopausal) Past multiple surgeries - Wertheim’s hysterectomy followed by Radiotherapy – carcinoma cervix 1986 - Laparotomy - intestinal obstruction 1990 - Repeated urethral dilatation - retention of urine 2008 - Abdominal Sacrocolpopexy - vaginal vault prolapse March 2010 Hypertension Hypothyroidism Osteoarthritis DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 5. General & Neurological Examination: normal POPQ Aa +2.0 Gh 7 Ap -3 Ba +1.0 Pb 3.5 Bp -3 C -5 TVL 7 D 0 STAGE III CYSTOCELE Urethral Hypermobility + Stress leak + DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 6. SENSATION RESULTS LEAK POINT PRESSURES SENSATION Bladder filling First Sensation 110 cc 10 cmH2O Strong Desire 280 cc 11 cmH2O Max Cyst Capacity 280 cc 15 cmH2O Bladder filling Pabd Pdet 1 156 cc 13 cmH2O 10 cmH2O 2 248 cc 10 cmH2O 7 cmH2O 3 276 cc 10 cmH2O 11 cmH2O Pdet DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 7. Total bladder capacity 281cc Peak flow rate 7ml/s Pdet at peak flow 15 cmH2O Average flow rate 3 ml/s Residual Urine 0 ml Opening Pdet 9 cmH O DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 8. Braided Suture Piercing bladder wall DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 9. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited Blind pit at Ant. Vaginal wall ( ? healed fistula opening) Negative Three Swab Test
  • 10. Suture Removal 3 weeks Cystocele Repair & Midurethral Sling Placement DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 11. Peak Flow Rate 15 ml/s Average Flow Rate 7 ml/s Voided Volume 267 ml Voided Time 24 s Flow Time 24 s Post Void Residual 150 cc DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 12. • Able to hold & void herself • Fully continent ( Pads not required) • Clean Intermittent Self Catheterisation (3 times a day)   DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 13. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 14. • 54 years • Recurrent UTI • On & off pinkish foul smelling vaginal discharge 1.5 yrs • Past Surgical History - Lap Hysterectomy 2 yrs back (Menorrhagia cause ? fibroid uterus) - Cholecystectomy 20 yrs back - Incisional hernia repair 16 yrs back • Co-morbidities - Hypertension 3-4 months - Diabetes Mellitus 3-4 months DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 15. Per speculum: - Black colored material at the apex of vaginal vault - Foul smelling black to brown dirty discharge soiling the walls of vaginal vault DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 16. Impression: Low Rectovaginal fistula DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 17. A black colored ? Suture at the apex of vaginal vault DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 18. On removal – black brown colored infected material drained.  Communicating path traced through a probe.  DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 19. Abdominal Repair DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 20. Vaginal opening traced DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 21. No communicating path into sigmoid colon or rectum DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 22. Edges of Vaginal opening freshened up & closed DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 23.  No foul smell discharge  Not a single episode of UTI   DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 24. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 25. • • • • 54 years Pain in left loin – 1 month Continuous urinary leakage – 1 month H/O present illness month - D & C for menorrhagia 4 months back. - f/b Vaginal hysterectomy with left oophorectomy after one - C/O continuous significant vaginal bleeding in postop - re-evaluated after 2 weeks & some stiches were put through vaginal route - developed high grade fever after 2 days f/b urinary incontinence • Past H/O - Tubal ligation 30 yrs back • No Co - morbidities DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 26. Findings: Moderate Left sided Hydroureteronephrosis with dilatation of left ureter in its entire extent with abrupt cut off at distal end, which appears to merge with vaginal stump DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 27. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 28. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 29. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 30. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 31. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 32. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 33. Abrupt cut off at 2 cm distance from left ureteric orifice DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 34. Post Hysterectomy Iatrogenic Left Ureteric Trauma with Vesico-vaginal fistula DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 35. Left Percutaneous Nephrostomy 4 weeks Cystoscopy + O’Conner’s VVF Repair* + Left Ureteric Reimplantation (stented) [ discharged on POD 5 with SPC in situ] “The best approach for complex fistulas is transabdominal using the O'Connors bivalve technique.” O'Connor VJ et al. Suprapubic closure of vesicovaginal fistula. J Urol. 1973;109:51–4. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 36. At 2 Weeks Findings: •Well maintained bladder outline •No leak DJ Stent removal done DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 37.  Normal KFT  Normal findings of DTPA Scan and USG Whole Abdomen   DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 38. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 39. • 31 years • Continuous urinary leakage per vaginum for 2 year • Past Surgical History - MTP with tubal ligation (continous leakage in postop) - Hysterectomy with reimplantation of right ureter - Cystoscopy (0.5 cm sized fistula inferomedial to left ureteric orifice, right ureteric orifice not seen) + LRGP + LDJS - 2 failed attempts of vaginal repair of VVF - LRGP + Left Laser endoureterotomy + Laser fulgration of VVF • No Co-morbidities DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 40.  USG KUB: B/L Chronic Renal Parenchymal Disease  KFT: Bld Urea 93 mg/dl S. Creatinine 4.76 mg/dl  Hb 8 g/dl  Urine C/S: E Coli >10 cfu/ml DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 41. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited Impression: B/L contracted Kidneys, Re-implantation of right ureter ? into bowel (dilated 8 mm), DJ Stent on left side, 4 mm sized focal defect in posterior wall of UB communcating to vaginal stump (fluid in endovaginal canal)
  • 42. Renal Transplantation after Fistula Repair DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 43. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 44. • 52 years • Continuous urinary leakage per vaginum for 2 year • Large bed sore over sacrum • Past History - Received multiple courses of chemoradiation for Ca Cervix (grade III) diagnosed in 1999 - Multiple cystoscopies for gross hematuria in 2009 - Cystoscopic fulgration & angioembolisation in Aug 2009 - Admitted in ICU for septicemia - on catheter removal at discharge noticed continuous leakage of urine • No Co-morbidities DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 45.  Left small sized kidney  Right normal sized kidney  No Ureterovaginal fistula/ no ureteric stricture DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 46.  Frozen  Large Pelvis Vesico-vaginal fistula DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 47.  Small capacity bladder  Fluffy tissue inside  Patchy inflammation  Supratrigonal large irregular hole at left side of posterior wall DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 48. Urinary Diversion ( Transverse Colonic Urinary Conduit) DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 49. POD3  Myelosuppresion with pancytopenic sepsis  B/L Parotitis with right parotid abscess  Respiratory failure with Metabolic Acidosis  Acute Renal Failure with Dyselectrolytemia  Liver Dysfunction with Hypoalbuminemia  Paralytic ileus POD 11  Anastomotic leakage Conservative Management in ICU by Multidisciplinary Team DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 50.  Went home on full recovery after 6 weeks  Doing well at 2years 6 months   DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 51.  Obstretical fistulas are associated with high incidence of recurrence and failure rates due to their large size and presence of ischaemic tissues. Arrow SS et al, Obstet Gynecol Surv. 1996;51:568–74.  Postsurgical fistulas are result of more direct and localised trauma to otherwise healthy tissue, so having better results after repair. Hadley HR. Vesicovaginal fistula. Curr Urol Rep. 2002;3:401–7. DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 52.  To date improvements in health care facilities may have led to change in etiological aspect of FGF.  Surgical correction is still a great challenge and requires a team approach for better results. “Prevention is better than cure". THANKS DR AMITA JAIN Confidential & Proprietary. Any use of this material without prior permission is strictly prohibited
  • 53. Medanta Institute of Kidney & Urology Dr. Amita Jain Urogynaecology Clinic 12th Floor, OPD Wing, Medanta -The Medicity Gurgaon, Haryana -122001, INDIA Tel: +91 124 4141 414 info@medanta.org www.medanta.org MOB. +91-9871136110 http://www.urogynecologistindia.in/ http://amitajainurogynaecolgist.blogspot.in/ http://www.linkedin.com/mbox?displayMBoxItem=&itemID=I225857003_75