This document contains information from Dr. Amita Jain, a urogynaecologist in India. It discusses female genital fistulas (FGF), which are abnormal connections between the bladder or urethra and the vagina. FGF is a significant problem worldwide, especially in developing countries. An estimated 2 million women live with fistulas, with 50,000 to 100,000 new cases annually. The backlog of women needing fistula repair is estimated to be as high as 99%. Prevention is emphasized as better than cure for this debilitating condition.
2.
Female Genital Fistula(FGF) is a socially debilitating
problem with important medicolegal implications.
In the developing nations, nearly 5 million women
annually suffer severe morbidity with obstetric
fistulae being the foremost on the list. (WHO 1991)
Around > 2 million women living with fistula, with
approximately 50,000 to 100,000 cases occurring
annually, mostly in Africa, Asia, and the Arab world.
Stanton C et al, Int J Gynaecol Obstet 2007, 99:S4-S9.
The unmet need for fistula repair is estimated to be
as high as 99%. Ahmed S et al, Int J Gynaecol Obstet 2007, 99:S1-S3.
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4. • 74 years
• C/O Involuntary leakage of urine with coughing, sneezing
& change in posture
• Co - morbidities
Old age (Postmenopausal)
Past multiple surgeries
- Wertheim’s hysterectomy followed by Radiotherapy –
carcinoma cervix 1986
- Laparotomy - intestinal obstruction 1990
- Repeated urethral dilatation - retention of urine 2008
- Abdominal Sacrocolpopexy - vaginal vault prolapse
March 2010
Hypertension
Hypothyroidism
Osteoarthritis
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5. General & Neurological Examination: normal
POPQ
Aa
+2.0
Gh
7
Ap
-3
Ba
+1.0
Pb
3.5
Bp
-3
C
-5
TVL
7
D
0
STAGE III CYSTOCELE
Urethral Hypermobility +
Stress leak +
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6. SENSATION RESULTS
LEAK POINT PRESSURES
SENSATION
Bladder
filling
First Sensation
110 cc
10 cmH2O
Strong Desire
280 cc
11 cmH2O
Max Cyst
Capacity
280 cc
15 cmH2O
Bladder filling
Pabd
Pdet
1
156 cc
13 cmH2O
10 cmH2O
2
248 cc
10 cmH2O
7 cmH2O
3
276 cc
10 cmH2O
11 cmH2O
Pdet
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7. Total bladder capacity
281cc
Peak flow rate
7ml/s
Pdet at peak flow
15 cmH2O
Average flow rate
3 ml/s
Residual Urine
0 ml
Opening Pdet
9 cmH O
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Blind pit at Ant. Vaginal
wall ( ? healed fistula
opening)
Negative Three
Swab Test
10. Suture Removal
3 weeks
Cystocele Repair
&
Midurethral Sling Placement
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11. Peak Flow Rate
15 ml/s
Average Flow Rate
7 ml/s
Voided Volume
267 ml
Voided Time
24 s
Flow Time
24 s
Post Void Residual
150 cc
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12. •
Able to hold & void herself
•
Fully continent ( Pads not required)
•
Clean Intermittent Self Catheterisation
(3 times a day)
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14. • 54 years
• Recurrent UTI
• On & off pinkish foul smelling vaginal
discharge
1.5 yrs
• Past Surgical History
- Lap Hysterectomy 2 yrs back (Menorrhagia cause ? fibroid
uterus)
- Cholecystectomy 20 yrs back
- Incisional hernia repair 16 yrs back
• Co-morbidities
- Hypertension 3-4 months
- Diabetes Mellitus 3-4 months
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15. Per speculum:
- Black colored material at the apex of
vaginal vault
- Foul smelling black to brown dirty
discharge soiling the walls of vaginal vault
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17. A black colored
? Suture at the
apex of vaginal
vault
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18. On removal – black brown colored infected material
drained.
Communicating path traced through a probe.
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19. Abdominal Repair
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21. No communicating
path into sigmoid
colon or rectum
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22. Edges of
Vaginal
opening
freshened up
& closed
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23. No
foul smell discharge
Not
a single episode of UTI
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25. •
•
•
•
54 years
Pain in left loin – 1 month
Continuous urinary leakage – 1 month
H/O present illness
month
- D & C for menorrhagia 4 months back.
- f/b Vaginal hysterectomy with left oophorectomy after one
- C/O continuous significant vaginal bleeding in postop
- re-evaluated after 2 weeks & some stiches were put through
vaginal route
- developed high grade fever after 2 days f/b urinary
incontinence
• Past H/O
- Tubal ligation 30 yrs back
• No Co - morbidities
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26. Findings:
Moderate Left sided
Hydroureteronephrosis with
dilatation of left ureter in its entire
extent with abrupt cut off at distal
end, which appears to merge with
vaginal stump
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33. Abrupt cut off at 2 cm
distance from left ureteric
orifice
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34. Post Hysterectomy
Iatrogenic Left Ureteric
Trauma with Vesico-vaginal
fistula
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35. Left Percutaneous Nephrostomy
4 weeks
Cystoscopy + O’Conner’s VVF Repair* + Left Ureteric
Reimplantation (stented)
[ discharged on POD 5 with SPC in situ]
“The best approach for complex fistulas is transabdominal using the
O'Connors bivalve technique.” O'Connor VJ et al. Suprapubic closure of vesicovaginal
fistula. J Urol. 1973;109:51–4.
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36. At 2 Weeks
Findings:
•Well maintained
bladder outline
•No leak
DJ Stent removal
done
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37.
Normal KFT
Normal findings of DTPA Scan and
USG Whole Abdomen
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39. • 31 years
• Continuous urinary leakage per vaginum for 2 year
• Past Surgical History
- MTP with tubal ligation (continous leakage in postop)
- Hysterectomy with reimplantation of right ureter
- Cystoscopy (0.5 cm sized fistula inferomedial to left
ureteric orifice, right ureteric orifice not seen) + LRGP + LDJS
- 2 failed attempts of vaginal repair of VVF
- LRGP + Left Laser endoureterotomy + Laser fulgration
of VVF
• No Co-morbidities
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40.
USG KUB: B/L Chronic Renal Parenchymal Disease
KFT: Bld Urea 93 mg/dl
S. Creatinine 4.76 mg/dl
Hb 8 g/dl
Urine C/S: E Coli >10 cfu/ml
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Impression:
B/L contracted Kidneys,
Re-implantation of right ureter ? into
bowel (dilated 8 mm),
DJ Stent on left side,
4 mm sized focal defect in posterior
wall of UB communcating to vaginal
stump (fluid in endovaginal canal)
42. Renal Transplantation after
Fistula Repair
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44. • 52 years
• Continuous urinary leakage per vaginum for 2 year
• Large bed sore over sacrum
• Past History
- Received multiple courses of chemoradiation for Ca
Cervix (grade III) diagnosed in 1999
- Multiple cystoscopies for gross hematuria in 2009
- Cystoscopic fulgration & angioembolisation in Aug
2009
- Admitted in ICU for septicemia - on catheter removal
at discharge noticed continuous leakage of urine
• No Co-morbidities
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45. Left
small sized kidney
Right
normal sized kidney
No
Ureterovaginal fistula/ no
ureteric stricture
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46. Frozen
Large
Pelvis
Vesico-vaginal fistula
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47.
Small capacity bladder
Fluffy tissue inside
Patchy inflammation
Supratrigonal large irregular hole at
left side of posterior wall
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48. Urinary Diversion
( Transverse Colonic Urinary Conduit)
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49. POD3
Myelosuppresion with pancytopenic sepsis
B/L Parotitis with right parotid abscess
Respiratory failure with Metabolic Acidosis
Acute Renal Failure with Dyselectrolytemia
Liver Dysfunction with Hypoalbuminemia
Paralytic ileus
POD 11
Anastomotic leakage
Conservative Management in ICU by Multidisciplinary Team
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50.
Went home on full recovery after 6 weeks
Doing well at 2years 6 months
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51.
Obstretical fistulas are associated with high
incidence of recurrence and failure rates due to
their large size and presence of ischaemic
tissues. Arrow SS et al, Obstet Gynecol Surv. 1996;51:568–74.
Postsurgical fistulas are result of more direct
and localised trauma to otherwise healthy
tissue, so having better results after repair. Hadley
HR. Vesicovaginal fistula. Curr Urol Rep. 2002;3:401–7.
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52.
To date improvements in health care facilities may
have led to change in etiological aspect of FGF.
Surgical correction is still a great challenge and
requires a team approach for better results.
“Prevention is better than cure".
THANKS
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53. Medanta Institute of Kidney & Urology
Dr. Amita Jain
Urogynaecology Clinic
12th Floor, OPD Wing,
Medanta -The Medicity
Gurgaon, Haryana -122001, INDIA
Tel: +91 124 4141 414 info@medanta.org www.medanta.org
MOB. +91-9871136110
http://www.urogynecologistindia.in/
http://amitajainurogynaecolgist.blogspot.in/
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