1. Respiratory regulation of Acid-Base Balance DR. SUMREENA MANSOOR ASSISTANT PROF OF BIOCHEMISTRY DEPT OF BIOCHEMISTRY & MOLECULAR BIOLOGY

2. Arterial Blood Gas (ABG) pH, pCO 2 , pO 2 – Measured directly HCO 3 - , O 2 saturation (usually) – Calculated from pH, pCO 2 , and pO 2

15. 9 year old with H/O asthma, audibly wheezing x 1 week, has not slept in 2 nights; presents sitting up and using accessory muscles to breath with audible wheezes

18. 57-year-old male with COPD, home oxygen dependence, daily chronic sputum production, is treated with several types of metered dose inhalers. No other medications. He is in his usual state.

20. The patient described in above problem develops increasing shortness of breath, purulent sputum production, and increased weakness requiring emergency room visit. He appears to be in moderate respiratory distress peripheral cyanosis.

22. MALE, AGED 70 YEARS, WITH RESPIRATORY AND METABOLIC FAILURE DUE TO COPD. HE WAS ADMITTED TO ICU AND MECHANICALLY VENTILATED