We discuss several of our past and current OSGi-based solutions for defense systems, mining equipment, construction equipment, industrial automation, and automotive/telematics domains. We present some best practices for building flexible, cross-platform, high-performance embedded application and the resulting lessons learned along the way. We demonstrate how the Eclipse Runtime Components and Frameworks can be used to access communication buses such as CAN, J1939, J1850, and MIL-STD-1553. Finally, we explain how using OSGi and Equinox can simplify the development, testing, and deployment of your next application, whether embedded or not.