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Chapter 1:
Form, Function, and Life

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Anatomy vs. Physiology
โ€ข Anatomy: form of things
โ€“ Goal: study how structure relates to function
โ€ข Physiology: function (activity) of things
โ€“ Goal: study how the body works

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Organisms: Characteristics

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Form and Function

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Building Blocks of Life

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Environment and Life

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Gradients

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Homeostasis

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Homeostasis and President Reagan

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Remember This
โ€ข Negative feedback keeps systems tightly regulated
near their set point and thus promotes stability.

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Positive Feedback

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Directional Terms

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Remember This
โ€ข You can remember the order of word parts by the
mnemonic PRS:
โ€ข Prefix
โ€ข Root
โ€ข Suffix
โ€ข Example: pericarditis

โ€ข periโ€“ = around (prefix)
โ€ข cardia = heart (root)
โ€ข โ€“itis = meaning inflammation (suffix)
Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Planes and Sections
โ€ข Frontal plane: any plane that runs vertically (straight up
and down) from superior (above) to inferior (and divides
structures into anterior and posterior parts
โ€ข Also called coronal planeโ€”cuts along this plane are
called frontal or coronal sections
โ€ข Sagittal plane: vertical plane that divides structures into
right and left parts. It runs from superior to inferior and is
perpendicular to a frontal plane.
โ€ข Sagittal sections: cross-sections cut by this plane
โ€ข Mid-sagittal sections: cuts right down the middle
Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Planes and Sections (contโ€™d)
โ€ข Transverse plane: one parallel to the horizon that divides
structures into superior and inferior parts. It runs from
anterior (front) to posterior (rear) and is perpendicular to
both frontal and sagittal planes.
โ€ข Also called horizontal planeโ€”cuts along this plane are
called transverse sections
โ€ข Oblique plane: any plane not perpendicular to a frontal,
sagittal, or transverse (horizontal) plane

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Planes and Sections (contโ€™d)

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Body Regions

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Body Cavities

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Thoracic Membranes and Cavities

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Abdominal Quadrants

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Abdominal Regions

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Language of Disease
โ€ข Disease: an unhealthful state of abnormal form and
function due to the effects of injury
โ€ข Acute disease (e.g., ear infection)
โ€“ Arises quickly
โ€“ Lasts a short time
โ€“ Has specific symptoms
โ€ข Chronic disease (e.g., arthritis) starts slowly with
nonspecific symptoms and may last a lifetime

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Language of Disease (contโ€™d)
โ€ข Signs are direct, measurable observations by an
examiner (nurse, physician assistant, physician, etc.)
such as body temperature and heart rate.
โ€ข Symptoms are complaints reported by the patient
or by someone else on behalf of the patient and are
a part of the medical history.
โ€ข A syndrome is a collection of clinical signs and
symptoms.
โ€“ sunburn: skin that is red (sign), painful (symptom),
and swollen (sign)
Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Language of Disease (contโ€™d)
โ€ข Pathology: study of changes in bodily structure and
function that occur as a result of disease
โ€ข Etiology: cause of the injury or disease
โ€“ Idiopathic: of unknown cause
โ€“ Iatrogenic: byproduct of medical diagnosis or
treatment

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Language of Disease (contโ€™d)
โ€ข Pathogenesis: natural history and development
of a disease
โ€ข Pathophysiology: abnormal manner in which the
incorrect function is expressed
โ€ข Lesion: the structural (anatomic) abnormality produced
by injury

Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins

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A&p chapter 1 pp

  • 1. Chapter 1: Form, Function, and Life Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 2. Anatomy vs. Physiology โ€ข Anatomy: form of things โ€“ Goal: study how structure relates to function โ€ข Physiology: function (activity) of things โ€“ Goal: study how the body works Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 3. Organisms: Characteristics Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 4. Form and Function Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 5. Building Blocks of Life Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 6. Environment and Life Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 7. Gradients Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 8. Homeostasis Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 9. Homeostasis and President Reagan Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 10. Remember This โ€ข Negative feedback keeps systems tightly regulated near their set point and thus promotes stability. Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 11. Positive Feedback Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 12. Directional Terms Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 13. Remember This โ€ข You can remember the order of word parts by the mnemonic PRS: โ€ข Prefix โ€ข Root โ€ข Suffix โ€ข Example: pericarditis โ€ข periโ€“ = around (prefix) โ€ข cardia = heart (root) โ€ข โ€“itis = meaning inflammation (suffix) Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 14. Planes and Sections โ€ข Frontal plane: any plane that runs vertically (straight up and down) from superior (above) to inferior (and divides structures into anterior and posterior parts โ€ข Also called coronal planeโ€”cuts along this plane are called frontal or coronal sections โ€ข Sagittal plane: vertical plane that divides structures into right and left parts. It runs from superior to inferior and is perpendicular to a frontal plane. โ€ข Sagittal sections: cross-sections cut by this plane โ€ข Mid-sagittal sections: cuts right down the middle Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 15. Planes and Sections (contโ€™d) โ€ข Transverse plane: one parallel to the horizon that divides structures into superior and inferior parts. It runs from anterior (front) to posterior (rear) and is perpendicular to both frontal and sagittal planes. โ€ข Also called horizontal planeโ€”cuts along this plane are called transverse sections โ€ข Oblique plane: any plane not perpendicular to a frontal, sagittal, or transverse (horizontal) plane Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 16. Planes and Sections (contโ€™d) Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 17. Body Regions Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 18. Body Cavities Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 19. Thoracic Membranes and Cavities Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 20. Abdominal Quadrants Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 21. Abdominal Regions Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 22. Language of Disease โ€ข Disease: an unhealthful state of abnormal form and function due to the effects of injury โ€ข Acute disease (e.g., ear infection) โ€“ Arises quickly โ€“ Lasts a short time โ€“ Has specific symptoms โ€ข Chronic disease (e.g., arthritis) starts slowly with nonspecific symptoms and may last a lifetime Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 23. Language of Disease (contโ€™d) โ€ข Signs are direct, measurable observations by an examiner (nurse, physician assistant, physician, etc.) such as body temperature and heart rate. โ€ข Symptoms are complaints reported by the patient or by someone else on behalf of the patient and are a part of the medical history. โ€ข A syndrome is a collection of clinical signs and symptoms. โ€“ sunburn: skin that is red (sign), painful (symptom), and swollen (sign) Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 24. Language of Disease (contโ€™d) โ€ข Pathology: study of changes in bodily structure and function that occur as a result of disease โ€ข Etiology: cause of the injury or disease โ€“ Idiopathic: of unknown cause โ€“ Iatrogenic: byproduct of medical diagnosis or treatment Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 25. Language of Disease (contโ€™d) โ€ข Pathogenesis: natural history and development of a disease โ€ข Pathophysiology: abnormal manner in which the incorrect function is expressed โ€ข Lesion: the structural (anatomic) abnormality produced by injury Copyright ยฉ 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins

Editor's Notes

  1. Major Themes Life is defined by specific characteristics. Form and function are intimately related at every level of life. Life is sustained by specific things in the external environment. Life is maintained by strict, automatic reactions that adjust the internal environment. Precise communication is a key attribute of science and requires specialized descriptive language.
  2. Notes: Types of anatomy: Gross anatomy: structures seen with naked eye Microscopic anatomy: invisible to naked eye Three states: Life: form and function combine to produce biologic activity Illness: abnormal form or function Death: end of biologic activity
  3. Characteristics of life: all living things share four functions: - Organization - Metabolism - Adaptation -Reproduction Question: We shiver when it is cold to generate more heat. Which function of life does this represent? Answer: Adaptation Notes: Organism: complete life form that can function independently of other life forms Organization is maintained by boundaries that separate the internal environment from the external environment. Metabolism involves anabolism and catabolism.
  4. The human hand, with thumb rotated at 90ยฐ, is capable of a pincer grip. The monkey hand, with thumb parallel to other fingers, only allows a less precise (but stronger) palmar grip. Question: True or false: the structure of the monkeyโ€™s hand refers to its physiology. False; structure refers to anatomy
  5. Question: Which is the smallest building block illustrated in this figure? Answer: atoms
  6. Astronauts carry their life-sustaining environment with them. Question: Which necessities of life are illustrated? Answer: Pressure, oxygen, temperature Notes: Elements we normally get from our environment include pressure, oxygen, heat, water, and nutrients. Pressure includes static pressure (such as atmospheric pressure) and dynamic pressure (e.g., strong wind, blood pressure). Blood pressure is controlled by volume, heart activity, blood vessel diameter Oxygen is about 20% of air. Absorbed by the lungs, it unlocks chemical nutrients from food and keeps cells alive. Body temperature must be maintained within extremely narrow limits, but livable environmental temperature can vary widely. Heat is generated by metabolism, dissipated by radiation, increased when cold by shivering, and decreased when hot by sweating. Nutrients are burned for energy and used as building blocks. Water is a solvent for chemical reactions, smoothes movements of various body parts, carries nutrients to cells and removes wastes, transports messenger and regulatory molecules.
  7. Altitude gradient of a roof Pressure gradient in a blood vessel Concentration gradient in a cell Question: In part B, where is the pressure greatestโ€”inside or outside the blood vessel? Answer: Inside Notes: Gradient: difference in the quantity or concentration of a physical value between two areas
  8. Negative feedback restores homeostasis. Negative feedback is used to maintain a constant temperature in a room (inner circle) and in a person (outer circle). Question: Name the effectors that respond to a change in body temperature. Answer: Sweat glands and blood vessels in skin Notes: Homeostasis depends on negative feedback: process that reflexively keeps systems tightly regulated near their set point and thus promotes stability Set point is optimum range (e.g., 98.6 ยฐF) Sensor detects deviations from set point Deviations trigger opposing (negative) response to return to set point.
  9. The disruptions in homeostasis caused by the bullet are shown in red. Homeostatic adjustments and medical interventions are in yellow. Question: Why was Reaganโ€™s blood pressure low? Answer: Because he lost blood volume Notes: Homeostasis: bodyโ€™s collective communication and control effort to maintain internal conditions within a narrow, stable physiologic range Example: Cardiovascular system increases blood flow if blood pressure falls. Analogy: Bodyโ€™s systems work like a symphony. Negative feedback controls thousands of functions, including levels of sodium and potassium in blood, weight, and blood pressure. Homeostasis keeps body stable. Failure of homeostasis causes illness and even death.
  10. Positive feedback reinforces a condition. Positive feedback loops often terminate in cataclysmic events, such as childbirth or death. Question: Would uterine contractions increase or decrease the activation of the cervical nerve endings (the sensors)? Answer: Increase Notes: Positive feedback: increases intensity of effect Unlike negative feedback, positive feedback: - Controls only a few functions - Enhances rather than reduces change - Does not stabilize, but pushes reactions to an ending or to exhaustion Example: childbirth
  11. Directional terms refer to the body in the anatomic position. Question: Which part is more lateralโ€”the ears or the nose? Answer: Ears Notes: Directional terms: describe the position of a part relative to another part or a subdivision of a part Example:Inferior sternum (lower part of breastbone) Example: Incision superior to (above) the fifth rib Based on standard anatomic position
  12. Notes: Medical terms often come from Greek or Latin roots. Prefixes precede the root. Suffixes follow the root.
  13. Transverse plane: one parallel to the horizon that divides structures into superior and inferior parts.
  14. Planes divide the body in specific ways. Cuts along these planes result in different sections. Question: Which plane divides the body into right and left halves? Answer: Sagittal
  15. Regional terms and surface landmarks describe important areas and points on the surface of a body in the anatomical position. Question: What is the adjective describing the entire foot? Answer: Pedal Notes: Surface anatomy: -head: skull and face -neck -trunk or torso: chest, abdomen, pelvis -upper limb: shoulder, armpit, arm, forearm, wrist, hand -lower limb: buttock, thigh, leg, ankle, foot
  16. Body organs exist in hollow spaces lined by membranes. Question: Which cavity is superiorโ€”pelvic or abdominal? Answer: abdominal Notes: Dorsal cavities: Cranial cavity: contains the brain Spinal cavity: contains the spinal cord Formed of bone and lined with membranes Ventral cavity: Thoracic cavity: lies above the diaphragm; contains the heart, lungs, and large vessels Abdominopelvic cavity: lies below the diaphragm -Abdominal cavity: contains most of the digestive organs and abdominal glands, such as the stomach, liver, gall bladder, pancreas, and most of the intestines -Pelvic cavity: contains part of the large intestine and reproductive organs
  17. Minute cavities separate the two layers of the pericardium and the two pleurae. The double-layered thoracic membranes formed when the heart and lungs pushed their way into fetal cavities. Question: Name the membrane in contact with the heart wall. Answer: Visceral pericardium Notes: Membranes in the thoracic and abdominopelvic cavities: Pericardium: covers the heart Pleurae: cover the lungs Peritoneum: covers abdominal and pelvic organs Membrane layers: Visceral attaches to organs Parietal attaches to cavity walls
  18. A. Abdominal quadrants Notes: Upper right quadrant: liver Right lower quadrant: appendix Peritoneum: covers abdominal and pelvic organs
  19. B. Abdominal regions Question: Which region is inferiorโ€”the iliac or hypochondriac region? Answer: Iliac Notes: Abdominal regions: -Two horizontal lines below ribs and above hip bones -Two vertical lines near nipples
  20. Notes: Rememberโ€”both acute and chronic diseases can range in severity from mild to life-threatening.