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Germs:  The Good, the Bad, and the Ugly Clara Pelfrey, Ph.D. Cleveland Clinic & Case Western Reserve University
[object Object],[object Object],[object Object],What are germs?
Some common conditions caused by germs Condition Kind of Germ Common Symptoms Athelete’s Foot Fungus Red, scaly, itchy rash on feet Chickenpox Virus Fever; headache; red, pimple-like rash Common Cold Virus Sore throat; runny or stuffed-up nose; coughing; sneezing Ear infection Bacteria Pain and/or swelling in ear; fever Flu Virus Fever; headache; sore throat; coughing; muscle aches Strep Throat Bacteria Fever; sore throat; headache; swollen tonsils or yellow patches at back of throat
[object Object],[object Object]
In the Middle Ages, people thought illnesses were due to  demons . ,[object Object],[object Object]
[object Object],[object Object],[object Object]
Three general shapes of bacteria: Round (coccus,  plr. cocci) Rod  (bacillus,  plr. bacilli) Spiral (spirillum, plr. spirilla)  Example: Staphylococcus epidermidis Example:  Escherichia coli Example: Treponema pallidum                                           
Computer-generated video showing the motions of an E. coli bacterium
Types of bacteria
“ Streak plate” on a petri dish to isolate bacteria
Bacterial colonies on agar
Label agar plates on the  BOTTOM … to prevent condensation
Enterotubes help hospitals identify bacteria
“ The Good, the Bad  and the Ugly” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The “Good guys” See if you can figure them out! Game show quiz:
BEER YEAST
Blue cheese Blue mold
Champagne Yeast
Compost Soil Bacteria
Oil spill These "oil-eating" bacteria are shown swimming around large droplets of oil.
Oenococcus   Oeni  -lactic acid bacterium Wine
Yogurt “ Live active cultures”  Lactobacillus acidophilus
Penicillin Penicillium
Penicillium mold inhibiting bacterial growth Mold Bacteria Zone of inhibition
Bread Baker’s yeast
Sausage & Salami Soy sauce Pickles
The “Bad” guys
Click on the picture to go to a web video on proper sneezing technique When you sneeze, air explodes out of your lungs at a speed of 100 miles per hour.  The air in a cough travels at 500 mph!
To cover or not cover  your mouth? ,[object Object],[object Object],[object Object]
The “Ugly”
Bacteria growing on your teeth can cause tooth decay
Bacterial colonies
Moldy bread!
Relative size of a bacterium, compared to a virus
Play HOW BIG?   MOVIE
What are viruses? ,[object Object],[object Object],[object Object],[object Object],[object Object]
DNA Viruses
RNA Viruses
AIDS Virus structure
AIDS Virus particles
Louis Pasteur ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pasteur gives the first Rabies vaccine
Benjamin Franklin
Conclusions ,[object Object],[object Object],[object Object],[object Object],[object Object]

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