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  ARDS ITACCS  Key West 2006 Ruben J Azocar, M.D. Assistant Professor of Anesthesiology Boston University School of Medicine
ARDS: Definitions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS: Causes
ARDS:Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS:Pathogenesis ,[object Object],[object Object],[object Object]
ARDS:Pathogenesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS:Pathogenesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS: Exudative Phase ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS:Pathogenesis
ARDS: Exudative Phase ,[object Object]
ARDS: Fibroproliferative phase ,[object Object],[object Object],[object Object]
ARDS: Fibroproliferative phase ,[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS: Fibroproliferative phase ,[object Object],[object Object]
ARDS:Pathogenesis
ARDS:Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS:  Treatment
ARDS:  Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome   The Acute Respiratory Distress Syndrome Network  N Engl J Med 2000;342:1301-8 ,[object Object],[object Object]
NIH/ARDS Network ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ventilation with Lower Tidal Volumes ,[object Object]
ARDS:Permissive Hypercapnia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Kregenov et al: Hypercapnic acidosis and mortality in ALI  CCM 2006;34:1-7 ,[object Object],[object Object],[object Object]
Effect of a protective ventilation strategy on mortality in ARDS Amato M et al NEJM 1998;338:347-354 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Optimal “PEEP” ,[object Object],[object Object],[object Object]
Slutsky, A. S. et al. N Engl J Med 2006;354:1839-1841 Ventilation of an ex Vivo Rat Lung
Higher Vs. Lower PEEP in Patients With ARDS,  NEJM 2004 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BUT….. ,[object Object],[object Object]
ARDS:  Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recruitment maneuvers ,[object Object],[object Object],[object Object]
Recruitment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recruitment ,[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS Treatment ,[object Object],[object Object],[object Object],[object Object]
ARDS Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Swan and ARDS ,[object Object],[object Object],[object Object],[object Object],[object Object]
APRV ,[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS:Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS: Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS: Steroids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS:  Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ARDS: Questions

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