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Coagulation / Fibrinolytic   Factors in PCOS
The  Alternative  Hypothesis : ,[object Object],[object Object]
Carotid IMT in PCOS Click for larger picture
Hemodynamic   Measures   in PCOS Click for larger picture
Correlation of Various Subclinical CHD Measures Click for larger picture
Interaction of PCOS and Age in IMT Click for larger picture
Lancet 1997; 350 (suppl I):15 Click for larger picture
Lancet 1997;350:21 Click for larger picture
Introduction ,[object Object],[object Object]
Introduction (cont.) ,[object Object]
Characteristics of PCOS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Affects 5 to 10 percent of US Women, and the condition is marked by:
Research   Questions ,[object Object],[object Object]
Current Study Population ,[object Object],[object Object],[object Object]
Selected Clinical and Lifestyle Factors in PCOS Cases and Controls- Preliminary Data VARIABLES (1993-94 Data) CASES (n=46) CONTROLS (n=59) * p    .05 ** p    .001
Selected Lipid and Hormone Levels in PCOS Cases and Controls- Preliminary Data VARIABLES (1993-4 Data) CASES (n=46) CONTROLS (n=59) * p    .05 ** p    .001
Differences in CAI in PCOS Cases vs. Controls by Age   * p = 0.004 ** p = 0.021
Analysis of CAI Predictors in PCOS Cases and Controls ,[object Object],[object Object],[object Object],[object Object],[object Object]
Regression - Fixed Model Predictors P-value of Predictors Model Adjusted R 2 Model Significance Forced entry of CVD risk factors: Dependent variable =  CAI
Regression - Lipids and Insulin Predictors P-value of Predictors Model Adjusted R 2 Model Significance Individual entry of lipids and insulin to CVD fixed model: Dependent Variable = CAI
Regression - PCOS Status Predictors P-value of Predictors Model Adjusted R 2 Model Significance Entry of PCOS status to CVD fixed model including LDL: Dependent variable =  CAI
Conclusions ,[object Object],[object Object]
Conclusions (cont.) ,[object Object],[object Object]
Implications ,[object Object]
Evelyn O. Talbott A544 Crabtree Hall Pittsburg, PA (412) 624-3074

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Pcos 2

  • 1. Coagulation / Fibrinolytic Factors in PCOS
  • 2.
  • 3. Carotid IMT in PCOS Click for larger picture
  • 4. Hemodynamic Measures in PCOS Click for larger picture
  • 5. Correlation of Various Subclinical CHD Measures Click for larger picture
  • 6. Interaction of PCOS and Age in IMT Click for larger picture
  • 7. Lancet 1997; 350 (suppl I):15 Click for larger picture
  • 8. Lancet 1997;350:21 Click for larger picture
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14. Selected Clinical and Lifestyle Factors in PCOS Cases and Controls- Preliminary Data VARIABLES (1993-94 Data) CASES (n=46) CONTROLS (n=59) * p  .05 ** p  .001
  • 15. Selected Lipid and Hormone Levels in PCOS Cases and Controls- Preliminary Data VARIABLES (1993-4 Data) CASES (n=46) CONTROLS (n=59) * p  .05 ** p  .001
  • 16. Differences in CAI in PCOS Cases vs. Controls by Age * p = 0.004 ** p = 0.021
  • 17.
  • 18. Regression - Fixed Model Predictors P-value of Predictors Model Adjusted R 2 Model Significance Forced entry of CVD risk factors: Dependent variable = CAI
  • 19. Regression - Lipids and Insulin Predictors P-value of Predictors Model Adjusted R 2 Model Significance Individual entry of lipids and insulin to CVD fixed model: Dependent Variable = CAI
  • 20. Regression - PCOS Status Predictors P-value of Predictors Model Adjusted R 2 Model Significance Entry of PCOS status to CVD fixed model including LDL: Dependent variable = CAI
  • 21.
  • 22.
  • 23.
  • 24. Evelyn O. Talbott A544 Crabtree Hall Pittsburg, PA (412) 624-3074