This document provides guidance for interacting with patients with various special needs or circumstances. It recommends maintaining eye contact and minimizing distractions for hearing impaired patients. For visually impaired patients, it suggests using touch, cues, and describing locations. When interviewing speech impaired or low comprehension patients, it advises using simple questions, written formats, and pictures. Interpreters should be used for non-English speakers and the patient, not interpreter, should be directly questioned. It also gives tips for interacting with patients who are crying, anxious, angry, hostile, sexually aggressive, intoxicated, seriously ill, or older adults.