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The Intersection of Medical
           Research and Public Health

                              Kimberly M. Brown

April 9, 2010
University of Florida
                        Spring 2010 Public Health Day
Research!America



  Make research to improve
   health a higher national
           priority
Interning with Research!America

             Tasks                        Opportunities

• Contributor to the New Voices   • National Forum and Advocacy
  for Research Blog and online      Awards
  advocacy community              • Congressional Briefing on
• Contributor to the Research       Biomedical Research funding
  Advocate member newsletter      • Created and implemented a
• Updated the                       social media marketing
  Research!America website’s        strategy for New Voices for
  NIH ARRA funding                  Research initiative
                                    • Twitter: @NV4Research
                                  • Capital Science 2010
                                    Conference
The Historical Relationship Between
      Medicine and Public Health


                                           Practice
                                        Transformation             • Advancement
   • Infectious
     disease                                                         of scientific
                                   • Bacteriology                    knowledge
   • Mutual
     dependence
                                                                           Functional
         Collaboration                                                     Separation




Source: Lasker R. Medicine and Public Health: The Power of Collaboration
Rationale-Childhood Obesity

                Year                 Excess Crises               Needless Deaths
                2020                          600                           130
                2025                        5,400                           550
                2030                        11,000                          1,500
                2035                        37,000                          3,700




Sources: Bibbins-Domingo, K et al. Adolescent Overweight and Future Adult
Coronary Heart Disease.
Rationale-HIV/AIDS




Source: El-Sadr, W et al. Aids in America: Forgotten but Not Gone
Methods
•   Literature review
    •   CINHAL
    •   PubMed
•   Research!America fact sheets and poll data
•   Media alerts
Objectives
•   To show how medical research and public
    health intersect to address health problems
    •   Past- Influenza
    •   Present-Childhood Obesity
    •   Future- HIV/AIDS
•   Identify key public health advocacy messages
Influenza
Spanish Influenza (1918-1920)
       • Estimated 50 to
         100 million people
         were killed
         worldwide
       • Average life span
         reduced by 10
         years
       • Most deadly for
         people ages 20 to
         40 years old

Source: "The 1918 Influenza Pandemic." Stanford University.
Public Health Achievements
•   Influenza Vaccine-
    1945
•   Sanitation
    •   Hand-washing
    •   Coughing/sneezing
        techniques
    •   Alcohol based hand
        sanitizer
•   Social Distancing
Medical Advancements
•   Over the counter
    medications
    •   Fever reducers- 1946
•   Anti-virals
    •   Zanamivir (Relenza)-
        1989
    •   Oseltamivir (Tamiflu)-
        1999
Childhood Obesity
Public Health Interventions
                 •   Nutrition programs
                 •   Vending machine
                     removal
                 •   Full calorie sodas
                     removed from
                     schools
                 •   Walking school buses
                 •   Promotion of physical
                     education
Gastric Banding in Severely Obese
     Adolescents


           Gastric Banding                        Lifestyle Change
               Group                                    Group

         • 84% lost more                         • 12% lost more
           than 50% of                             than 50% of
           excess weight                           excess weight
         • Average weight                        • Average weight
           loss: 76.1 lbs                          loss: 6.6 lbs

Source: Ogden CL et al. Prevalence of overweight and obesity in
the United States, 1999-2004.
First Lady Obama’s Let’s Move
Campaign

       Healthy Choices     Accessible and
       • New easy-to-      Affordable
         understand        Healthy Food
         nutrition         • Eliminating food
         labeling            deserts
       • Medical           • Increasing the
         education on        availability of
         obesity             fresh produce

       Healthier           Physical Activity
       Schools             • President’s
       • Nutrition           Physical Fitness
         education           Challenge
         programs          • Presidential
       • School lunch        Active Lifestyle
         standardization     Award
HIV/AIDS
Advancements in the Treatment of
      HIV/AIDS
                                                •   1983-Identified the
                                                    HIV virus
                                                •   1987-AZT became
                                                    first approved
                                                    treatment for HIV




Source: GH Wynn et al. Antiretrovirals , Part 1: Overview, History and
Focus on Protease Inhibitors.
Public Health Interventions
•   HIV testing
•   Safe sex education
•   Work with at-risk
    populations
•   Prevention of
    mother-to-child
    transmission
•   Behavior changing
Working Together
     •   Pre-exposure prophylaxis (PrEP)
         •   Using anti-retrovirals (ARVs) as a prevention tool
             in non-infected communities
         •   Take ARVs prior to HIV exposure
         •   Goal is to lower risk of infection




Source: CDC’s Clinical Studies of Pre-Exposure Prophylaxis for HIV Prevention
Majority of Americans Want More
   Funding for Research
     How many cents out of each health dollar do you think we SHOULD spend?


    26 cents or more                   12%

         15-25 cents                   13%
                                                                              70%
         10-15 cents              9%

           7-10 cents                                            36%

            5-6 cents                           21%

            0-4 cents             9%


Source: Your Congress–Your Health Survey, June 2009
Charlton Research Company for Research!America
Funding for CDC
     CDC implements research-based programs to prevent chronic and infectious diseases,
     lower injury rates, limit tobacco use, protect the population from pandemics, and
     mitigate environmental health risks. Which of the following statements most accurately
     reflects your view?
                                                              We should increase
                                                              funding for core
              10%                                             programs at CDC to
                                                 45%          improve public health

                                                              We should maintain
                                                              current funding levels
                                                              for CDC core programs
                                                              because other budget
                                                              items take precedence
                                                              Funding for CDC core
                                                              programs is not a
         45%
                                                              priority
Source: Your Congress–Your Health Survey, June 2009
Charlton Research Company for Research!America
Political Opportunities Supporting
Collaboration
               •   2009 American
                   Recovery and
                   Reinvestment Act
               •   Obama’s proposed FY
                   2011 budget
               •   Health insurance reform
Relationship to Public Health
Values
Contribution to the larger field of
public health
Community Dimensions of
                               Systems Thinking
Practice
•   Recognizes community       •   Describes how public
    linkages and                   health operates within a
    relationships among            larger system
    multiple factors           •   Identifies key values
    affecting health               and a shared vision as
•   Seeks the collaboration        guiding principles for
    of community partners          community action
    to promote the health of
    the population
Competencies
                 • Informing, educating and empowering
                   people about health issues
  Master of      • Mobilizing community partnerships
                   and action to solve health problems
 Public Health   • Communicating effectively with public
                   health constituencies in oral and
                   written forms


                 • Identify, retrieve, summarize, manage
 Management        and communicate public health
                   information
  and Policy     • Demonstrate the principles of problem
                   solving and crisis management
Competencies

                 • Communicate effectively with
 Biostatistics     investigators in other areas of
                   public health

  Social &       • Demonstrate communication skills
 Behavioral        key to public health workforce
  Sciences         participation and advocacy

                 • Identify key sources of
Epidemiology       epidemiologic data and data
                   collection methodology
Future Recommendations
•   Working in conjunction with public health and
    medical research organizations in order to find
    new ways to collaborate
•   Conduct advocacy trainings for public health
    and medical professionals
Acknowledgments
Questions?

                      Kimberly M. Brown

April 9, 2010   Spring 2010 Public Health Day

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The Intersection of Medical Research and Public Health

  • 1. The Intersection of Medical Research and Public Health Kimberly M. Brown April 9, 2010 University of Florida Spring 2010 Public Health Day
  • 2. Research!America Make research to improve health a higher national priority
  • 3. Interning with Research!America Tasks Opportunities • Contributor to the New Voices • National Forum and Advocacy for Research Blog and online Awards advocacy community • Congressional Briefing on • Contributor to the Research Biomedical Research funding Advocate member newsletter • Created and implemented a • Updated the social media marketing Research!America website’s strategy for New Voices for NIH ARRA funding Research initiative • Twitter: @NV4Research • Capital Science 2010 Conference
  • 4. The Historical Relationship Between Medicine and Public Health Practice Transformation • Advancement • Infectious disease of scientific • Bacteriology knowledge • Mutual dependence Functional Collaboration Separation Source: Lasker R. Medicine and Public Health: The Power of Collaboration
  • 5. Rationale-Childhood Obesity Year Excess Crises Needless Deaths 2020 600 130 2025 5,400 550 2030 11,000 1,500 2035 37,000 3,700 Sources: Bibbins-Domingo, K et al. Adolescent Overweight and Future Adult Coronary Heart Disease.
  • 6. Rationale-HIV/AIDS Source: El-Sadr, W et al. Aids in America: Forgotten but Not Gone
  • 7. Methods • Literature review • CINHAL • PubMed • Research!America fact sheets and poll data • Media alerts
  • 8. Objectives • To show how medical research and public health intersect to address health problems • Past- Influenza • Present-Childhood Obesity • Future- HIV/AIDS • Identify key public health advocacy messages
  • 10. Spanish Influenza (1918-1920) • Estimated 50 to 100 million people were killed worldwide • Average life span reduced by 10 years • Most deadly for people ages 20 to 40 years old Source: "The 1918 Influenza Pandemic." Stanford University.
  • 11. Public Health Achievements • Influenza Vaccine- 1945 • Sanitation • Hand-washing • Coughing/sneezing techniques • Alcohol based hand sanitizer • Social Distancing
  • 12. Medical Advancements • Over the counter medications • Fever reducers- 1946 • Anti-virals • Zanamivir (Relenza)- 1989 • Oseltamivir (Tamiflu)- 1999
  • 14. Public Health Interventions • Nutrition programs • Vending machine removal • Full calorie sodas removed from schools • Walking school buses • Promotion of physical education
  • 15. Gastric Banding in Severely Obese Adolescents Gastric Banding Lifestyle Change Group Group • 84% lost more • 12% lost more than 50% of than 50% of excess weight excess weight • Average weight • Average weight loss: 76.1 lbs loss: 6.6 lbs Source: Ogden CL et al. Prevalence of overweight and obesity in the United States, 1999-2004.
  • 16. First Lady Obama’s Let’s Move Campaign Healthy Choices Accessible and • New easy-to- Affordable understand Healthy Food nutrition • Eliminating food labeling deserts • Medical • Increasing the education on availability of obesity fresh produce Healthier Physical Activity Schools • President’s • Nutrition Physical Fitness education Challenge programs • Presidential • School lunch Active Lifestyle standardization Award
  • 18. Advancements in the Treatment of HIV/AIDS • 1983-Identified the HIV virus • 1987-AZT became first approved treatment for HIV Source: GH Wynn et al. Antiretrovirals , Part 1: Overview, History and Focus on Protease Inhibitors.
  • 19. Public Health Interventions • HIV testing • Safe sex education • Work with at-risk populations • Prevention of mother-to-child transmission • Behavior changing
  • 20. Working Together • Pre-exposure prophylaxis (PrEP) • Using anti-retrovirals (ARVs) as a prevention tool in non-infected communities • Take ARVs prior to HIV exposure • Goal is to lower risk of infection Source: CDC’s Clinical Studies of Pre-Exposure Prophylaxis for HIV Prevention
  • 21. Majority of Americans Want More Funding for Research How many cents out of each health dollar do you think we SHOULD spend? 26 cents or more 12% 15-25 cents 13% 70% 10-15 cents 9% 7-10 cents 36% 5-6 cents 21% 0-4 cents 9% Source: Your Congress–Your Health Survey, June 2009 Charlton Research Company for Research!America
  • 22. Funding for CDC CDC implements research-based programs to prevent chronic and infectious diseases, lower injury rates, limit tobacco use, protect the population from pandemics, and mitigate environmental health risks. Which of the following statements most accurately reflects your view? We should increase funding for core 10% programs at CDC to 45% improve public health We should maintain current funding levels for CDC core programs because other budget items take precedence Funding for CDC core programs is not a 45% priority Source: Your Congress–Your Health Survey, June 2009 Charlton Research Company for Research!America
  • 23. Political Opportunities Supporting Collaboration • 2009 American Recovery and Reinvestment Act • Obama’s proposed FY 2011 budget • Health insurance reform
  • 24. Relationship to Public Health Values
  • 25. Contribution to the larger field of public health Community Dimensions of Systems Thinking Practice • Recognizes community • Describes how public linkages and health operates within a relationships among larger system multiple factors • Identifies key values affecting health and a shared vision as • Seeks the collaboration guiding principles for of community partners community action to promote the health of the population
  • 26. Competencies • Informing, educating and empowering people about health issues Master of • Mobilizing community partnerships and action to solve health problems Public Health • Communicating effectively with public health constituencies in oral and written forms • Identify, retrieve, summarize, manage Management and communicate public health information and Policy • Demonstrate the principles of problem solving and crisis management
  • 27. Competencies • Communicate effectively with Biostatistics investigators in other areas of public health Social & • Demonstrate communication skills Behavioral key to public health workforce Sciences participation and advocacy • Identify key sources of Epidemiology epidemiologic data and data collection methodology
  • 28. Future Recommendations • Working in conjunction with public health and medical research organizations in order to find new ways to collaborate • Conduct advocacy trainings for public health and medical professionals
  • 30. Questions? Kimberly M. Brown April 9, 2010 Spring 2010 Public Health Day