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ALMA  Alberta Livestock & Meat Agency Ltd.  Canadian Bovine Genomics Workshop September 14, 2009 Calgary, Alberta
International Beef Genomics: An Australian Example Heather Burrow Canadian Bovine Genomics Workshop September 14, 2009
CRC for Beef Genetic Technologies ‘ Beef industry growth by Gene Discovery, Gene Expression and Accelerated Adoption’ …
‘ Gene Discovery’ ,[object Object],[object Object],[object Object],[object Object],to address 4 key industry priorities …
DNA test for tenderness Moving from single DNA tests … Gene Discovery
to DNA marker panels and GWAS  (SNPs associated with phenotypes for traits of interest)   …   to genomic selection  (selection based on markers alone) Gene Discovery
2005:  10k Affymetrix SNP chip 2007:  Simulation study results 2008:  54k Illumina SNP chip – collaboration between Canada, USA and Australia Some history …
[object Object],[object Object],[object Object],[object Object],CRC Commercialisation Rationale
To increase adoption and industry impact … ,[object Object],[object Object],[object Object],Commercialisation
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],+ + + Size of effects Relationships Size of r g s Heritabilities, variances MARKER ASSISTED EBV (EBV m ) FOR TENDERNESS Method will apply to other traits in future ,[object Object],[object Object]
[object Object],Genetic Prediction Models
[object Object],Phenotypic Prediction Models Research  Models Developed & tested with  research and industry data Fat (& Weight) Prediction Tool ‘ BeefSpecs’ Feedlot Performance Tool Decision Optimisation Tool Better  Meet  Market  Specifications  = ++ $$ Maternal productivity tool Improve Production Efficiency = ++ $$
[object Object]
International Genomics Collaborations ,[object Object],[object Object],[object Object]
‘ Beef Information Nucleus’ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NewCo Possibility? NewCo Centralized management of all databases; Not for profit  company BINs $ Data  Cattle breeders & breed societies MLA Donor Company Matching funds Matching funds Company C Company D Company B Company A Preferred Partners Annual technology access fee Data  $ Data  Services Access to data >2 years old Most recent 2-years’ data for ‘validation’ Exclusive research on non-core traits Fund distribution $ Manage databases & DNA bank Administer & coordinate BINs Manage BIN infrastructure
Current position ,[object Object],[object Object],[object Object],[object Object]
Beef CRC Post-2012 Thinking ,[object Object],[object Object],[object Object],[object Object]
Technology Performance Optimal Technology Performance INNOVATION  GROWTH  MATURITY TIME X  Human Sheep Beef Dairy X X X
[object Object],[object Object],[object Object],[object Object],[object Object],Industry Needs to 2030
Livestock  Genomics ‘Initiative ’ ,[object Object],[object Object],[object Object],[object Object],[object Object]
Possible Industry Outcomes ,[object Object],[object Object],[object Object],[object Object]
Industry Outcomes ,[object Object],[object Object],[object Object],[object Object]

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CBGW Heather Burrow

  • 1. ALMA Alberta Livestock & Meat Agency Ltd. Canadian Bovine Genomics Workshop September 14, 2009 Calgary, Alberta
  • 2. International Beef Genomics: An Australian Example Heather Burrow Canadian Bovine Genomics Workshop September 14, 2009
  • 3. CRC for Beef Genetic Technologies ‘ Beef industry growth by Gene Discovery, Gene Expression and Accelerated Adoption’ …
  • 4.
  • 5. DNA test for tenderness Moving from single DNA tests … Gene Discovery
  • 6. to DNA marker panels and GWAS (SNPs associated with phenotypes for traits of interest) … to genomic selection (selection based on markers alone) Gene Discovery
  • 7. 2005: 10k Affymetrix SNP chip 2007: Simulation study results 2008: 54k Illumina SNP chip – collaboration between Canada, USA and Australia Some history …
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16. NewCo Possibility? NewCo Centralized management of all databases; Not for profit company BINs $ Data Cattle breeders & breed societies MLA Donor Company Matching funds Matching funds Company C Company D Company B Company A Preferred Partners Annual technology access fee Data $ Data Services Access to data >2 years old Most recent 2-years’ data for ‘validation’ Exclusive research on non-core traits Fund distribution $ Manage databases & DNA bank Administer & coordinate BINs Manage BIN infrastructure
  • 17.
  • 18.
  • 19. Technology Performance Optimal Technology Performance INNOVATION GROWTH MATURITY TIME X Human Sheep Beef Dairy X X X
  • 20.
  • 21.
  • 22.
  • 23.