SOSventures is an accelerator VC that focuses on synthetic biology through its IndieBio accelerator. It has invested in companies developing technologies like growing milk in vats instead of cows, producing egg whites without chickens, and synthesizing THC without marijuana plants. IndieBio portfolio companies fall into two main categories: synthetic biology companies producing materials from microbes, and bio-tools companies creating technologies like affordable DNA printers and lab-on-a-chip devices. Regulatory issues around topics like GMOs differ between regions like the US and Europe.

1. Confidential - Copyright 2015
Premoney
12 June 2015
Accelerating
Biology
Producing Milk Without Cows, Egg Whites Without Chickens,
THC Without Pot (What It Means for the Planet...& the Market)
@indbio - @sosventures

2. Confidential - Copyright 2015
Synthetic biology &
biodesign
San Francisco & Cork
Who we are: SOSV - the Accelerator VC
SOSventures is the Accelerator VC
China/Asia - Software/
Apps
Chinaccelerator
InteractionX
Human-computer
interaction. .
Hardware/Robotics/IOT
Shenzhen, China.
Hax FoodX
“Disruptive Food”
New York
Hardware Distribution
Boost
Vertical
theme-based
accelerators
Deep domain
expertise & hands-on,
supportive model
Eternal spring of
high quality
investment
opportunities
Concentrated in
Key Areas /
Megatrends
De-risk with long
and effective due
diligence process
@indbio - @sosventures
SOSV: Accelerating Biology
IndieBio

3. Confidential - Copyright 2015
130 companies graduate
SOSV accelerators per year
SOSventures is the Accelerator VC
•IndieBio
•Hax
•FoodX
40
30
20
20
10 •Other
•Chinaccelerator
HealthMaterialsFood
‘A new way for
scientists, entrepreneurs, and
makers
to shape their own destiny
and
make something that
matters’
1/3 of accelerator portfolio
@sosventures@indbio - @sosventures
SOSV: Accelerating Biology

4. Confidential - Copyright 2015
BioSystems
IndieBio teams fall into 2 main buckets
SOSventures is the Accelerator VC
Grow milk in vats rather
than in cows.
M
The Nespresso
machine of DNA
synthesis
Producing ex-vivo egg
whites without chickens
Growing rhino horns
from DNA and 3D
printed keratin
“Lab on a Chip” : $10
real time blood
diagnostics
Synthetic Biology
@indbio - @sosventures
SOSV: Accelerating Biology

5. Confidential - Copyright 2015
What is biology?
SOSventures is the Accelerator VC
Think:
“Engineered lifeforms”
@indbio - @sosventures
SOSV: Accelerating Biology
“The study of animals and plants…”
What is synthetic biology?

6. Confidential - Copyright 2015
That was then…
SOSventures is the Accelerator VC
@indbio - @sosventures
SOSV: Accelerating Biology
Feedstock Organism Output Yummy

7. Confidential - Copyright 2015
SOSventures is the Accelerator VC
this is now.
@indbio - @sosventures
SOSV: Accelerating Biology
Feedstock Organism Yummy

9. Confidential - Copyright 2015
Then: resource intensive
SOSventures is the Accelerator VC
Raw Inputs Plant/Animal
Raw output
@indbio - @sosventures
SOSV: Accelerating Biology

10. Confidential - Copyright 2015
Now: Resource Efficient, Scalable
SOSventures is the Accelerator VC
Develop
organisms
Ferment
feedstock
Purify
@indbio - @sosventures
SOSV: Accelerating Biology

11. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Data Processing
@indbio - @sosventures
SOSV: Accelerating Biology
Input Data Programs Output

12. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Bioprocessing
@indbio - @sosventures
SOSV: Accelerating Biology
Data =
Feedstock
Programs =
DNA
Output =
Desired Protein/
Molecules/Chemicals

13. Confidential - Copyright 2015
$40m
Series B
SOSventures is the Accelerator VC
?
VCs
production
@indbio - @sosventures
SOSV: Accelerating Biology
Last week: Bolt Threads w/ $40m funding round

14. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Fundable Categories in the new Biotech
@indbio - @sosventures
SOSV: Accelerating Biology
Synthetic Biology
Output materials: chemicals, compounds, foods,
materials, drugs, etc.
BioSystems Tools
Picks & Shovels: bioreactors, robotics, process
improvements, DNA printers, Crisper CAS9, etc.
cloud biolabs, bioprocessing plants, yield
improvement services, info services
Biomedical Design
Biotreatments & drug discovery: therapeutic
applications, new treatment methods.
BioSystems Infrastructure

15. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Fundable Categories in the new Biotech
@indbio - @sosventures
SOSV: Accelerating Biology
Synthetic Biology
Output materials: chemicals, compounds, foods,
materials, drugs, etc.
Grow milk in vats rather
than in cows.
M
Producing ex-vivo egg
whites without chickens
Growing rhino horns
from DNA and 3D
printed keratin
Next generation microbes for
industrial chemicals
Production of THC without
production of Marijuana plants

16. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Fundable Categories in the new Biotech
@indbio - @sosventures
SOSV: Accelerating Biology
BioSystems Tools
The Nespresso
machine of DNA
synthesis
“Lab on a Chip” : $10
real time blood
diagnostics
Sub $1,000 bioreactor
Sub $2,000 liquid
handling robot
Picks & Shovels: bioreactors, robotics, process
improvements, DNA printers, Crisper CAS9, etc.

17. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Fundable Categories in the new Biotech
@indbio - @sosventures
SOSV: Accelerating Biology
cloud biolabs, bioprocessing plants, yield
improvement services, info services
BioSystems Infrastructure
Predictive DNA analysis, processing every possible variant
Bioprocessing optimization
Cloud services for bioprocessing
Github for life sciences

18. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Fundable Categories in the new Biotech
@indbio - @sosventures
SOSV: Accelerating Biology
Biomedical Design
Biotreatments & drug discovery: therapeutic
applications, new treatment methods
The Solution for Gaucher’s Disease
A sustainable supply for Horseshoe Crab Blood
Diagnostic DNA computer for tropical diseases
Crowdsourced bacteria
for drug discovery

19. Confidential - Copyright 2015
SOSventures is the Accelerator VC
Regulatory Issues
@indbio - @sosventures
SOSV: Accelerating Biology
US vs. Europe
What’s a GMO?
Biosimilar
Orphan Diseases

20. Confidential - Copyright 2015
Growing rhino horns
from DNA and 3D
printed keratin
Producing ex-vivo egg
whites without chickens
The Nespresso machine of
DNA analysis
Representative SOSventures Indie.Bio Investments
Grow milk in vats rather
than in cows.
SOSventures is the Accelerator VC
“Lab on a Chip” : $10 real
time blood diagnostics
M
SOSv: Accelerating Biology
@indbio - @sosventures