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Topic Refinement
1. Topic Refinement Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov
5. Topic Refinement in the Comparative Effectiveness Review (CER) Process Develop Topic Identify and triage topics based on appropriateness, importance, desirability of new research/duplication, feasibility, and potential impact. Refine Topic Identify patient intervention, comparator, outcomes, timing, and setting of each topic. Review Topic Prepare topic, search for and select studies, abstract data, analyze and synthesize data, and present findings. Engage Stakeholders in Clarifying Areas for Future Research Identify future research needs and inform real world health care decisions.
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13. Devise an Analytic Framework* *See Analytic Frameworks module Phung OJ, et al. Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients With Cystic Fibrosis [draft report]. Available at: http://www.effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/?pageaction= displayproduct&productid=391.
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23. Topic Refinement Process: UCONN/HH EPC Example (IV) Phung OJ, et al. Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients With Cystic Fibrosis [draft report]. Available at: http://www.effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/?pageaction= displayproduct&productid=391. UCONN/HH EPC = University of Connecticut/Hartford Hospital Evidence-based Practice Center