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Running head: INTERVENTIONS FOR DECREASING POST OP VTE                                   1 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
          Critical Appraisal  
Angela K. Rosa 
Point Loma Nazarene University  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
INTERVENTIONS FOR DECREASING POST OP VTE                                                            2 
Critical Appraisal  
Introduction 
Venous thromboembolism complications or VTEs are exceedingly common among 
postoperative patients in the hospital. VTEs can take many different forms such as a deep vein 
thrombosis or a pulmonary embolism. Most postoperative patients choose to delay and limit 
mobilization due to their postoperative pain, but doing so may increase and predispose them to a 
greater risk for developing a VTE.  Regardless of the specific form they come in, they are the 
leading cause of morbidity and mortality in the United States with incidences as common as, 117 
per 100,000 postoperative patients (Cassidy, Rosenkranz & McAneny, 2014). For having such a 
high rate of occurrence it brings about the question, what interventions, as opposed to receiving 
the standard of care, would decrease the likelihood of developing postoperative venous 
thromboembolisms? These interventions are important to discover and implement in the nursing 
practice because they would greatly decrease the likelihood of patients developing any type of 
VTE. Based on the article by Michael R. Cassidy, Pamela Rosenkranz & McAneny, ​Reducing 
Postoperative Venous Thromboembolism Complications with a Standardized Risk­Stratified 
Prophylaxis Protocol and Mobilization Program​, the interventions to decrease the likelihood of 
postoperative patients developing VTEs is to implement a standardized protocol for assessing a 
patient's individualized risk for developing a VTE​ ​along with implementing an early 
mobilization program after surgery (Cassidy et al., 2014).  
PICO Question 
P: Postoperative patients 
I: Risk stratified prophylaxis protocol and early mobilization 
 
 
INTERVENTIONS FOR DECREASING POST OP VTE                                                            3 
C: Standard care 
O: Decrease the likelihood of developing a VTE  
Search Strategies 
 
To find this article the writer employed Point Loma Nazarene University's research 
database called, MEDLINE with full text. The writer then used keywords such as, ​postoperative, 
venous thromboembolism, intervention, and early mobilization. ​With those specific keywords the 
writer successfully found the correct research article in full text that incorporated the keywords 
and more importantly, the PICO question.  
Synopsis of Article 
This study was conducted at the Boston Medical Center and was specifically directed 
towards postoperative patients. The study design used in this article was quasi­experimental. 
This was because there were no randomly assigned groups. The researcher wanted to 
demonstrate cause and effect. In further detail, the researcher wanted to find out if implementing 
a standardized scoring protocol for the risk of developing a venous thromboembolism and 
whether implementing an early mobilization program among all postoperative patients, affected 
the development of any form of venous thromboembolism. Those findings were then compared 
to a trial conducted before the experiment to the results collected at the end of the experiment.  
During the study a prophylaxis regimen called the Caprini Scoring System was selected for use. 
The Caprini Scoring System is a standardized risk stratified test that determines a patient's 
individualized risk for developing a VTE by giving them a score from 0<9 which notifies the 
physicians of which types of prophylaxis interventions to utilize as well as the recommended 
duration of their use. There are five different risk categories that a patient can be placed in such 
 
 
INTERVENTIONS FOR DECREASING POST OP VTE                                                            4 
as  lowest, low, moderate, high, and highest. After the patient's score was calculated, the data 
was entered into the hospital’s computer system which was designed to require that the surgeons 
implement and construct an order for all postoperative patients to receive their standardized 
prophylaxis protocol. However, the surgeon was still able to decline VTE prophylaxis protocol 
implementation if the risk of another complication outweighed the risk for developing a VTE. 
The study also included a standardized postoperative mobilization program which required the 
nurses to get each patient out of bed, sitting in a chair, or walking, starting with the day of 
surgery, at least 3 times daily. In which case, early mobilization was highly encouraged 
throughout this entire study (Cassidy et al., 2014).  
Study Purpose 
The purpose of this study was to put into action and to determine the effectiveness of a 
standardized VTE risk screening and intervention protocol such as an early mobilization program 
for reducing the likelihood of patients developing any form of a postoperative venous 
thromboembolism complication.  
Sample 
Before the implementation of the Caprini Scoring System and the early mobilization 
program, the incidences of DVTs at the Boston Medical Center were recoded as 1.9% of 1,569 
patients. After implementation of the two part VTE prevention program, the DVT complications 
decreased to 0.3% of 1,323 patients. As far as PE incidences, before implementation of the 
program, PE incidences were recorded as 1.1% of 1,569 patients, but decreased to 0.5% of 1,323 
patients (Cassidy et al., 2014).  
Major Study Findings 
 
 
INTERVENTIONS FOR DECREASING POST OP VTE                                                            5 
Before implementing the program, the hospital's baseline of care for postoperative 
patients was assessed by observing the mobilization practices 3 times daily. Clinical staff 
observed and recorded weather the patients were in bed, sitting in a chair, or walking at the time 
that they visited the patient. The clinical staff found that there was little to no VTE prevention 
requirements or guidelines before the study was implemented and carried out. Postoperative 
patients generally stayed in bed longer than desired putting them at a higher risk to develop a 
VTE. At times there may have been mobilization orders, but they were either too vague, 
forgotten, or even non existent. Before the program there was also no patient specific and 
individualized risk screening for VTEs, there were no electronic reminders in the computer’s 
charting system about implementing a VTE prophylaxis, and there was no system like the 
Caprini System being used to guide medical decisions and interventions. The study found that 
there was a great compliance rate with the program and prophylaxis protocol that had been 
created. Overall, the study found that with implementation of standardized patient specific VTE 
screening and an early mobilization program the incidences of postoperative patients developing 
a VTE significantly decreased (Cassidy et al., 2014).  
Limitations & Strengths 
The research article brought to question a few limitations in the study. The study only 
captured a representative sample of patients, those being solely the postoperative patients, rather 
than including all general hospitalized patients. In that case, a randomized trial wasn’t carried out 
using the Caprini Scoring System or early mobilization interventions since that specific 
exclusion criteria was in place. There may also have been some bias because different health 
systems and hospitals may possess higher levels of technology that can help them better visualize 
 
 
INTERVENTIONS FOR DECREASING POST OP VTE                                                            6 
and diagnose VTE complications thereby exceeding the use of  the Caprini Scoring System as 
used in the study. One last limitation of the study was that it never presented a clear number for 
the sample size that the study was being conducted on. On the other hand, there were also some 
strengths that the study possessed. For example, patient confidentiality was maintained 
throughout the entire study, a before and after trial was conducted in order to compare the 
findings and analyze the differences, the recording of patient information was well organized in 
the computer systems with the appropriate prophylaxis regimens automatically displayed for the 
surgeons to see, and lastly the standardization of the care made it easy for everyone to comply 
and provide the recommended prophylaxis protocol for each individual patient (Cassidy et al., 
2014).  
Evidence, Validity, & Reliability  
This article contained evidence on a level 6 basis because it was from a research 
journal based on a qualitative study. The study was reliable because it used a standardized and 
computerized scoring system to evaluate each patient's individualized risk for developing a VTE 
complication. This ensured that the results would be stable and consistent throughout all 
hospitals because it was a  standardized protocol and since it was consistent in automatically 
displaying the prophylaxis recommendation for for each postoperative patient for the surgeon to 
see and check the appropriate box accordingly. This research study was also very valid because 
the interventions measured directly what was intended to be measured which was represented 
with the results of the study. The research did not veer off into any other direction, instead it 
focused on the topic at hand and specifically measured how VTE complications could be 
 
 
INTERVENTIONS FOR DECREASING POST OP VTE                                                            7 
decreased. In doing so it was found that the incidences of VTE complications were significantly 
reduced among the postoperative patients that were included in the study.  
Evaluation of Article 
The results of this research study apply to the PICO question because the study focused 
on an intervention such as screening postoperative patients with a standardized VTE scoring 
system used to direct the prophylaxis regimen and an early mobilization program and found that 
the program being implemented decreased the likelihood of postoperative patients developing 
any form of VTE as opposed to the patient solely receiving the standard of care for VTE 
prevention, therefore putting the patient more at risk for developing a VTE complication. A 
recommendation for this research study includes, the implementation of this specific 
standardized program expanding to benefit and prevent the development of VTE complications 
among all general hospitalized patients rather than solely focussing on the postoperative patients. 
Practice change is warranted based on this study because it showed a significant decrease in the 
levels of VTE complications among postoperative patients which demonstrates its effectiveness 
in keeping the VTE incidence rates and complications down to a minimum.  
 
 
 
 
 
 
 
INTERVENTIONS FOR DECREASING POST OP VTE                                                            8 
References  
Cassidy, M. R., Rosenkranz, P., &McAneny, D. (2014). Reducing postoperative venous   
            thromboembolism complications with a standardized risk­stratified prophylaxis  
protocol and mobilization program.​ Journal Of The American College Of Surgeons​,  
218(6), 1095­1104. doi:10.1016/j.jamcollsurg.2013.12.061 
 
 
 

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