CTSI Director, S. Claiborne Johnston, MD, PhD, UCSF Associate Vice Chancellor of Research, presents some of the CTSI achievements and future goals.

1. CTSI Annual Retreat 2011 A Tale of Summer S. Claiborne Johnston, MD, PhD Associate Vice Chancellor of Research & CTSI Director

2. “Daddy, why does the train stop here?” - Teo Johnston, Age 8

4. Evolution of an Industry Start-up/building phase Hire Build basic structures Start slow but accelerate

5. 1857

6. Investors European investment groups.

10. US Regional Miles of Railroad

12. Railroads in 1918 1918

15. Number of industry-sponsored clinical trials # contracts n = 374 n = 423

16. Median Cycle Time for Industry Contractsfrom internal documents complete to final award – industry clinical trials Calendar days

17. IRB Approval Times 2009  139 days 2010  71 days

22. “Daddy, why does the train stop here?” - Teo Johnston, Age 8

24. Railroads in 1918 1918

25. 2006

28. Evolution of an Industry Start-up/building phase Hire Build basic structures Start slow but accelerate Sustainability phase Prepare for change; keep eyes on future Consider more flexible approaches Continue to innovate

29. CTSI Retreat 2011 12:45-3:00 “CTSI Idol” 3:00-3:20 Break 3:20-4:00 Defining Success 4:00-4:20 Early Stage Translation 4:20-4:40 Improving the Health of SF 4:40-5:00 Closing Discussion 5:00-6:00 Reception