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Femoral Access Site
  Complications
    FSH Care Suites Inservice
Advantages of Percutaneous
    Femoral Approach

• Dominant technique
• Does not require arteriotomy and arterial
    repair
•   Permits repeated site use for future
    angiograms
•   Suture closure of skin not necessary
Best Treatment - Prevention


• Accurate puncture technique
• Adequate compression for satisfactory
    initial hemostasis
    -  Careful attention!
•   Some complications unavoidable
•   Early recognition and intervention is key
Femoral Anatomy Review
•   Common Femoral Artery (CFA)
    - Between femoral nerve (medial) and vein (lateral)
•   Superficial Femoral Artery (SFA)
•   Profunda (Deep) Femoral Artery (PFA or DFA)
    - Branches from SFA
    - Thinner walls; atherosclerotic changes more likely
Angiographic Femoral Anatomy
Ideal Insertion Site



•   Below inquinal ligament

•   Above Common
    Femoral Artery (CFA)
    bifurcation
Seldinger Technique

•   Anterior and posterior a. wall
    pierced with needle encased
    in metal sheath
•   Both retracted into vessel,
    needle removed, outer
    cannula remains inside
•   Guidewire introduced
    through cannula
•   Less chance of intraluminal
    damage; but produces two
    holes in artery
Front Wall Technique for Vascular Access



•   Most likely route at FSH
•   Anterior wall pierced; needle
    immediately centered in artery
    lumen
•   Guidewire inserted through needle;
    needle removed; sheath fed over
    guidewire
•   Only one hole in artery; but greater
    chance for intraluminal damage
Anticoagulation During Catheterization


 • Two reasons
  - Reduce possibility of catheter-related
       embolic event (surface clots on catheter)
     - Decrease platelet aggregability to injured
       plaque
 •   Aspirin - AM of procedure
 •   Heparin - maintain ACT > 300 s
 •   Possible Glycoprotein Inhibitors
When to Remove Sheath


• Diagnostic procedures - immediately
• Interventional procedures - 4-6 hr
• Why delay for interventional procedures?
 - Give heparin time to dissipate
 - Ready access if coronary vessel closes
    abruptly
Time of Sheath Removal Important


• Short-window of time between
    subtherapeutic anticoagulation range and
    rebound thrombin activation
•   FSH standing orders - remove sheath as
    soon as PTT < 50 s
•   Complications increase with cannulation
    time duration
Ways to Achieve Hemostasis

•   Manual Pressure

•   Sandbags

•   Pressure Dressing

•   C-Clamp

•   Femostop

•   Vessel Seal/Closure Device
Pressure Devices




               FemoStop®
CompressAR®
Vessel Seal/Closure Devices




                          Vasoseal®
              Perclose®
Angioseal®
Patient Factors that Affect
      Complication Risk
• Hypertension
• Peripheral Vascular Disease
• Smoking
• Diabetes
• Obesity
• Anticoagulants
• Advanced Age
• Women
Procedural Factors that Affect
      Complication Risk

• Size of introducer sheath
• Repeated sheath changes
• Length of cannulation
• Post procedure heparin
• Failure to achieve adequate initial
  hemostasis when removing sheath
Four Signs of Blood Loss or Hemorrhage
              at Access Site



• Bulging mass in groin or thigh
• Pulsatility
• Bruit
• Tenderness in inguinal area
Possible Complications


• Retroperitoneal Hematoma or Bleed
• Hematoma
• Pseudoaneurysm
• Arteriovenous Fistula
• Neuropathy
• Arterial Occlusion
Hematoma


•   Blood loss may
    necessitate
    transfusion

•   Usually resolves
    in 2-3 weeks;
    can take much
    longer
Hematoma

Physical Findings              Nursing Interventions

•                              •
    Site pain/burning              Manual pressure above site

•                              •
    Difficulty moving hip/leg       Notify MD if severe
                                   or evolving
•   Possible tachycardia or
                               •
    hypotension                    VS q 15-30 min until
                                   hematoma stable, then
•   Red/purple skin                q 2-4 hr
    discoloration
                               •   Outline hematoma

                               •   Measure thigh girth
                                   q 1 hr until hematoma
                                   stable, then q 4-8 hr
Pseudoaneurysm
Often associated with puncture below CFA
bifurcation and initial inadequate hemostasis
Pseudoaneurysm
Physical Findings            Nursing Interventions

•                             •
    Groin pain/burning            Assess VS, groin site,
                                  pedal pules, and bruit
•   Back pain
                                  q 15 min while enlarging,
•   Swelling at groin site        then q 2 hr when stable
•                             •
    Ecchymosis                    Thigh girth q 1 hr
•                             •
    Pulsatile mass                CBC, PTT until < 30 s
•   Bruit
Ultrasound-Guided Compression

• Probe locates tract
    between artery and
    pseudoaneurysm; also
    used for pressure
•   Surgery when >2 cm



                   4-5 days after catheterization complicated
                   by significant groin hematoma
Arteriovenous Fistula


• Rare
• Usually forms when needle punctures
  artery and vein
 -  More likely when artery is punctured
    > 3 cm below inquinal ligament where
    veins are inferior to arteries
Arteriovenous Fistula
Physical Findings                   Nursing Interventions

•                                   •
    Swelling at groin site, leg         Notify MD
    pain
                                    •   Heart and lung sounds
•   Possible signs high-output          q 2 hr
    heart failure (arterial blood
                                    •   Check for decreased pedal
    shunting into venous bed)           pulses
•   Possible tachycardia and
                                    •   Check for bruit
    decreased BP
Neuropathy

• Rare
• After large hemorrhage or pseudoaneurysm
 - Pressure exerts on medial and intermediate
      cutaneous nerve
    - Usually resolves when cause resolves
•   Late complication from chronic accumulation
    of fluid that causes pressure/irritability
    - Usually resolves when cause resolves
Neuropathy
Physical Findings                  Nursing Interventions

•                                  •
    Pain, tingling at groin site       Notify MD
•                                  •
    Numbness at site or distal         Check for altered sensation
    leg                                and/or motor ability
•                                  •
    Motor difficulty in affected        Compare reflexes and ROM
    leg                                to unaffected leg
•                                  •
    Possible decreased patellar        In intermediate recovery
                                       phases, check VS, groin site
    tendon reflex
                                       and pulses per protocol,
•   Possible weakness of knee          then q 2 hr until symptoms
    extension                          resolve
•   Symptoms may occur as late
    as 3 months post procedure
Arterial Occlusion

• Very rare
• Can occur from large thrombus at
    puncture site. Use of anticoagulants
    occurance unlikely.
•   Large catheter most likely used in a small
    CFA
    - Diabetes
    - Female
Arterial Occlusion
Physical Findings            Nursing Interventions

•                            •
    Pain                         Notify MD
•                            •
    Pallor                       Assess VS, leg, pedal pulses
                                 q 15-30 min until
•   Paresthesia
                                 circulation restored
•   Pulseless
                             •   Use Doppler Ultrasound
                                 for pulse assessment
Care Post (4 fr.) Sheath Removal

• Site check with VS per unit protocol
• Instruct patient to call nurse for any sign of
    bleeding and apply manual pressure to site
    - Apply pressure to site while coughing,
      laughing, or sneezing
•   BR for 2 hr
    - Light restraint on affected limb
    - May elevate HOB 30º
Site Assessment

• Groin
 - How much ecchymosis and redness?
 - Is there any bleeding? How much?
 - Is there a raised mass? Does it pulsate?
 - Is there a bruit?
• Distal extremity
 - CMS (Color - Motion - Sensory)
Documentation


• Vital signs - HR, BP, RR, rhythm
• Neurovascular checks - affected limb
• Unexpected outcomes
• Nursing interventions/actions taken
• Evaluation
Mayo Study

• Implemented a new care standard
 - BR 3-4 hr (vs. 6)
 - HOB elevation (vs. flat)
 - Pressure dressing (vs. sandbag)
• 306 retrospective chart audits
• Compared complication rates for
  new vs. old standards
                           McCabe, et.al. (2001)
Minor Bleeding
              Mayo Study


• Defined as spurting, trickling, or oozing of
  blood not contained by Band-aid®
  - Possible redressing of site and/or
    additional compression (not > 30 min)
  - BR extended for more than small ooze
  - No hemodynamic instability
  - No medical or surgical intervention
                             McCabe, et.al. (2001)
Major Bleeding
              Mayo Study



• Spurting or brisk bleeding not controlled
  by site compression
  - Possible hemodynamic instability
  - Possible need for diagnostic tests and
    medical or surgical consultations


                             McCabe, et.al. (2001)
Minor Hematoma
              Mayo Study

• Collection of extravasated blood under
  skin that forms a soft raised surface - easily
  palpable
 -  Controlled by manual compression
 -  No hemodynamic instability
 -  No neurovascular compromise of
    affected limb
 -  No medical or surgical intervention
                              McCabe, et.al. (2001)
Major Hematoma
                 Mayo Study
• Collection of extravasated blood that may or
  may not be palpable. May occur under skin, in
  surrounding tissues, or extend into
  retroperitoneum
 -  Some classify size > 10 cm
 -  Increased risk for hemodynamic instability
 -  Possible neurovascular compromise
 -  Medical and/or surgical consultation with likely
    surgical intervention
                                McCabe, et.al. (2001)
Complication Rate
               Mayo Study
        Complication           No.         %
Hematoma - Minor               18         5.9
Hematoma - Major                9         2.9
Bleeding - Minor               13         4.2
Bleeding - Major                1         0.3
Pseudoaneurysm                  3         1.0
Arteriovenous fistula            0         0.0
Thorombosis of affected limb    0         0.0
Any major complication         10         3.3
Any complication               15        11.4
                               McCabe, et.al. (2001)
Timing After Sheath Removal
                   Mayo Study       N = 300

                            Total                  Major
              15

 Number of
Patients With 10                    End of BR
Complications
               5


               0
                      0-1    1-2      2-4       4-12       >12
                            Hours After Sheath Removal
                                            McCabe, et.al. (2001)
Amsterdam Study


• Coronary angioplasty, stenting, or both
    using femoral 6 fr. approach and Heparin
    5,000 IU
    - Also aspirin and Plavix
•   Manual compression followed by
    compression bandage
•   Ambulation at 2 hr
Amsterdam Study Results


• N = 300 (32% stent placements)
• Mean time to hemostasis = 9.6 min
• 5 (1.7%) bled at ambulation
• 9 had 5x5 cm hematoma at 48 hr
• All treated conservatively
• No late bleeding or vascular complications
U Minnesota Study (1)

• How well does a 4.5 kg (36 cm x 16 cm)
    sandbag with cross-sectional diameter of
    576 cm2 work?
    - It applies compression force of 3.4 g/cm2
      to stop bleeding in artery with intraluminal
      pressure ≥ 100 mmHg
•   Randomized study compared complications
    after angiography with and without sandbags
                                  Christensen, et. al. (1998)
U Minnesota (2)
Post Sheath Removal
                      Sandbag        Bandage
                      n = 174        n = 176

  Rebleeding            22               14


  Ecchymosis            13                8


  Hematoma              23               20

                                Christensen, et. al. (1998)
U Minnesota Study (3)

                          Sandbag Bandage
New fem bruit - 6 hr        0             0
New fem bruit - next AM     0             1
Ecchymosis - 6 hr           24           18
Ecchymosis - next AM        41           33
Hematoma - 6 hr             23           20
Hematoma - next AM          13           20
                            Christensen, et. al. (1998)
U Minnesota Study (4)
Early Complications (< 24 h)

                      Sandbag        Dressing

Any Bleeding             18               16

-Ooze                    8                7

-Brisk Bleeding          10               9

-Other                   2                1
                                Christensen, et. al. (1998)
U Minnesota Study (5)
Late Complications (1-30 days)
                        Sandbag         Dressing
                            2                1
Pseudoaneurysm
                            1                0
AV Fistula
                            3                2
Late Bleeding
                            1                0
Stroke
                            1                0
Loss of Pulse
                            1                2
Vascular Surgery
                            2                2
Other
                                  Christensen, et. al. (1998)
U Minnesota Study (6)

• Incidence of vascular complications not
    statistically significant between groups
•   Differences in patient satisfaction was
    statistically significant
                      Sandbag         Bandage
                      n = 174         n = 176
         Severe
                        18                 4
       Discomfort
       Moderate
                        6                  0
       Discomfort
                                Christensen, et. al. (1998)
Comparison of Physical Findings
                             Overview
                        Bulging    Pulsatile
                                                 Bruit*    Tenderness
                         Mass       Mass
                                   +/- pulse
Hematoma                varies                     no          yes
                                    waves

Pseudoaneurysm            yes         yes          yes         yes

AV Fistula                no           no          yes         no

* Some elderly adults have femoral bruits - atherosclerosis.
It’s a good idea to ascultate the groin pre procedure.
Patient Scenario - AV Fistula
Secondary to Pseudoaneurysm (1)
Patient Scenario - AV Fistula
Secondary to Pseudoaneurysm (2)
Patient Scenario - AV Fistula
Secondary to Pseudoaneurysm (3)

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Femoral Site Complications

  • 1. Femoral Access Site Complications FSH Care Suites Inservice
  • 2. Advantages of Percutaneous Femoral Approach • Dominant technique • Does not require arteriotomy and arterial repair • Permits repeated site use for future angiograms • Suture closure of skin not necessary
  • 3. Best Treatment - Prevention • Accurate puncture technique • Adequate compression for satisfactory initial hemostasis - Careful attention! • Some complications unavoidable • Early recognition and intervention is key
  • 4. Femoral Anatomy Review • Common Femoral Artery (CFA) - Between femoral nerve (medial) and vein (lateral) • Superficial Femoral Artery (SFA) • Profunda (Deep) Femoral Artery (PFA or DFA) - Branches from SFA - Thinner walls; atherosclerotic changes more likely
  • 6. Ideal Insertion Site • Below inquinal ligament • Above Common Femoral Artery (CFA) bifurcation
  • 7. Seldinger Technique • Anterior and posterior a. wall pierced with needle encased in metal sheath • Both retracted into vessel, needle removed, outer cannula remains inside • Guidewire introduced through cannula • Less chance of intraluminal damage; but produces two holes in artery
  • 8. Front Wall Technique for Vascular Access • Most likely route at FSH • Anterior wall pierced; needle immediately centered in artery lumen • Guidewire inserted through needle; needle removed; sheath fed over guidewire • Only one hole in artery; but greater chance for intraluminal damage
  • 9. Anticoagulation During Catheterization • Two reasons - Reduce possibility of catheter-related embolic event (surface clots on catheter) - Decrease platelet aggregability to injured plaque • Aspirin - AM of procedure • Heparin - maintain ACT > 300 s • Possible Glycoprotein Inhibitors
  • 10. When to Remove Sheath • Diagnostic procedures - immediately • Interventional procedures - 4-6 hr • Why delay for interventional procedures? - Give heparin time to dissipate - Ready access if coronary vessel closes abruptly
  • 11. Time of Sheath Removal Important • Short-window of time between subtherapeutic anticoagulation range and rebound thrombin activation • FSH standing orders - remove sheath as soon as PTT < 50 s • Complications increase with cannulation time duration
  • 12. Ways to Achieve Hemostasis • Manual Pressure • Sandbags • Pressure Dressing • C-Clamp • Femostop • Vessel Seal/Closure Device
  • 13. Pressure Devices FemoStop® CompressAR®
  • 14. Vessel Seal/Closure Devices Vasoseal® Perclose® Angioseal®
  • 15. Patient Factors that Affect Complication Risk • Hypertension • Peripheral Vascular Disease • Smoking • Diabetes • Obesity • Anticoagulants • Advanced Age • Women
  • 16. Procedural Factors that Affect Complication Risk • Size of introducer sheath • Repeated sheath changes • Length of cannulation • Post procedure heparin • Failure to achieve adequate initial hemostasis when removing sheath
  • 17. Four Signs of Blood Loss or Hemorrhage at Access Site • Bulging mass in groin or thigh • Pulsatility • Bruit • Tenderness in inguinal area
  • 18. Possible Complications • Retroperitoneal Hematoma or Bleed • Hematoma • Pseudoaneurysm • Arteriovenous Fistula • Neuropathy • Arterial Occlusion
  • 19. Hematoma • Blood loss may necessitate transfusion • Usually resolves in 2-3 weeks; can take much longer
  • 20. Hematoma Physical Findings Nursing Interventions • • Site pain/burning Manual pressure above site • • Difficulty moving hip/leg Notify MD if severe or evolving • Possible tachycardia or • hypotension VS q 15-30 min until hematoma stable, then • Red/purple skin q 2-4 hr discoloration • Outline hematoma • Measure thigh girth q 1 hr until hematoma stable, then q 4-8 hr
  • 21. Pseudoaneurysm Often associated with puncture below CFA bifurcation and initial inadequate hemostasis
  • 22. Pseudoaneurysm Physical Findings Nursing Interventions • • Groin pain/burning Assess VS, groin site, pedal pules, and bruit • Back pain q 15 min while enlarging, • Swelling at groin site then q 2 hr when stable • • Ecchymosis Thigh girth q 1 hr • • Pulsatile mass CBC, PTT until < 30 s • Bruit
  • 23. Ultrasound-Guided Compression • Probe locates tract between artery and pseudoaneurysm; also used for pressure • Surgery when >2 cm 4-5 days after catheterization complicated by significant groin hematoma
  • 24. Arteriovenous Fistula • Rare • Usually forms when needle punctures artery and vein - More likely when artery is punctured > 3 cm below inquinal ligament where veins are inferior to arteries
  • 25. Arteriovenous Fistula Physical Findings Nursing Interventions • • Swelling at groin site, leg Notify MD pain • Heart and lung sounds • Possible signs high-output q 2 hr heart failure (arterial blood • Check for decreased pedal shunting into venous bed) pulses • Possible tachycardia and • Check for bruit decreased BP
  • 26. Neuropathy • Rare • After large hemorrhage or pseudoaneurysm - Pressure exerts on medial and intermediate cutaneous nerve - Usually resolves when cause resolves • Late complication from chronic accumulation of fluid that causes pressure/irritability - Usually resolves when cause resolves
  • 27. Neuropathy Physical Findings Nursing Interventions • • Pain, tingling at groin site Notify MD • • Numbness at site or distal Check for altered sensation leg and/or motor ability • • Motor difficulty in affected Compare reflexes and ROM leg to unaffected leg • • Possible decreased patellar In intermediate recovery phases, check VS, groin site tendon reflex and pulses per protocol, • Possible weakness of knee then q 2 hr until symptoms extension resolve • Symptoms may occur as late as 3 months post procedure
  • 28. Arterial Occlusion • Very rare • Can occur from large thrombus at puncture site. Use of anticoagulants occurance unlikely. • Large catheter most likely used in a small CFA - Diabetes - Female
  • 29. Arterial Occlusion Physical Findings Nursing Interventions • • Pain Notify MD • • Pallor Assess VS, leg, pedal pulses q 15-30 min until • Paresthesia circulation restored • Pulseless • Use Doppler Ultrasound for pulse assessment
  • 30. Care Post (4 fr.) Sheath Removal • Site check with VS per unit protocol • Instruct patient to call nurse for any sign of bleeding and apply manual pressure to site - Apply pressure to site while coughing, laughing, or sneezing • BR for 2 hr - Light restraint on affected limb - May elevate HOB 30º
  • 31. Site Assessment • Groin - How much ecchymosis and redness? - Is there any bleeding? How much? - Is there a raised mass? Does it pulsate? - Is there a bruit? • Distal extremity - CMS (Color - Motion - Sensory)
  • 32. Documentation • Vital signs - HR, BP, RR, rhythm • Neurovascular checks - affected limb • Unexpected outcomes • Nursing interventions/actions taken • Evaluation
  • 33. Mayo Study • Implemented a new care standard - BR 3-4 hr (vs. 6) - HOB elevation (vs. flat) - Pressure dressing (vs. sandbag) • 306 retrospective chart audits • Compared complication rates for new vs. old standards McCabe, et.al. (2001)
  • 34. Minor Bleeding Mayo Study • Defined as spurting, trickling, or oozing of blood not contained by Band-aid® - Possible redressing of site and/or additional compression (not > 30 min) - BR extended for more than small ooze - No hemodynamic instability - No medical or surgical intervention McCabe, et.al. (2001)
  • 35. Major Bleeding Mayo Study • Spurting or brisk bleeding not controlled by site compression - Possible hemodynamic instability - Possible need for diagnostic tests and medical or surgical consultations McCabe, et.al. (2001)
  • 36. Minor Hematoma Mayo Study • Collection of extravasated blood under skin that forms a soft raised surface - easily palpable - Controlled by manual compression - No hemodynamic instability - No neurovascular compromise of affected limb - No medical or surgical intervention McCabe, et.al. (2001)
  • 37. Major Hematoma Mayo Study • Collection of extravasated blood that may or may not be palpable. May occur under skin, in surrounding tissues, or extend into retroperitoneum - Some classify size > 10 cm - Increased risk for hemodynamic instability - Possible neurovascular compromise - Medical and/or surgical consultation with likely surgical intervention McCabe, et.al. (2001)
  • 38. Complication Rate Mayo Study Complication No. % Hematoma - Minor 18 5.9 Hematoma - Major 9 2.9 Bleeding - Minor 13 4.2 Bleeding - Major 1 0.3 Pseudoaneurysm 3 1.0 Arteriovenous fistula 0 0.0 Thorombosis of affected limb 0 0.0 Any major complication 10 3.3 Any complication 15 11.4 McCabe, et.al. (2001)
  • 39. Timing After Sheath Removal Mayo Study N = 300 Total Major 15 Number of Patients With 10 End of BR Complications 5 0 0-1 1-2 2-4 4-12 >12 Hours After Sheath Removal McCabe, et.al. (2001)
  • 40. Amsterdam Study • Coronary angioplasty, stenting, or both using femoral 6 fr. approach and Heparin 5,000 IU - Also aspirin and Plavix • Manual compression followed by compression bandage • Ambulation at 2 hr
  • 41. Amsterdam Study Results • N = 300 (32% stent placements) • Mean time to hemostasis = 9.6 min • 5 (1.7%) bled at ambulation • 9 had 5x5 cm hematoma at 48 hr • All treated conservatively • No late bleeding or vascular complications
  • 42. U Minnesota Study (1) • How well does a 4.5 kg (36 cm x 16 cm) sandbag with cross-sectional diameter of 576 cm2 work? - It applies compression force of 3.4 g/cm2 to stop bleeding in artery with intraluminal pressure ≥ 100 mmHg • Randomized study compared complications after angiography with and without sandbags Christensen, et. al. (1998)
  • 43. U Minnesota (2) Post Sheath Removal Sandbag Bandage n = 174 n = 176 Rebleeding 22 14 Ecchymosis 13 8 Hematoma 23 20 Christensen, et. al. (1998)
  • 44. U Minnesota Study (3) Sandbag Bandage New fem bruit - 6 hr 0 0 New fem bruit - next AM 0 1 Ecchymosis - 6 hr 24 18 Ecchymosis - next AM 41 33 Hematoma - 6 hr 23 20 Hematoma - next AM 13 20 Christensen, et. al. (1998)
  • 45. U Minnesota Study (4) Early Complications (< 24 h) Sandbag Dressing Any Bleeding 18 16 -Ooze 8 7 -Brisk Bleeding 10 9 -Other 2 1 Christensen, et. al. (1998)
  • 46. U Minnesota Study (5) Late Complications (1-30 days) Sandbag Dressing 2 1 Pseudoaneurysm 1 0 AV Fistula 3 2 Late Bleeding 1 0 Stroke 1 0 Loss of Pulse 1 2 Vascular Surgery 2 2 Other Christensen, et. al. (1998)
  • 47. U Minnesota Study (6) • Incidence of vascular complications not statistically significant between groups • Differences in patient satisfaction was statistically significant Sandbag Bandage n = 174 n = 176 Severe 18 4 Discomfort Moderate 6 0 Discomfort Christensen, et. al. (1998)
  • 48. Comparison of Physical Findings Overview Bulging Pulsatile Bruit* Tenderness Mass Mass +/- pulse Hematoma varies no yes waves Pseudoaneurysm yes yes yes yes AV Fistula no no yes no * Some elderly adults have femoral bruits - atherosclerosis. It’s a good idea to ascultate the groin pre procedure.
  • 49. Patient Scenario - AV Fistula Secondary to Pseudoaneurysm (1)
  • 50. Patient Scenario - AV Fistula Secondary to Pseudoaneurysm (2)
  • 51. Patient Scenario - AV Fistula Secondary to Pseudoaneurysm (3)