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Creating a Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis (CAMERA)—Taking Metagenomics to Light Speed Invited Talk  ONR Review Scripps Institution of Oceanography, UCSD June 27, 2006 Dr. Larry Smarr Director, California Institute for Telecommunications and Information Technologies Harry E. Gruber Professor,  Dept. of Computer Science and Engineering Jacobs School of Engineering, UCSD
Two New Calit2 Buildings Provide  New Laboratories for “Living in the Future” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],UC Irvine www.calit2.net Preparing for a World in Which  Distance is Eliminated… UC San Diego
The OptIPuter Project – Creating High Resolution Portals  Over Dedicated Optical Channels to Global Science Data ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],NIH Biomedical Informatics NSF EarthScope and ORION Research Network
OptIPuter Scalable Adaptive Graphics Environment (SAGE) Allows Integration of HD Streams Photo: David Lee,  NCMIR, UCSD OptIPortal–  Termination Device  for the OptIPuter Global Backplane
PI Larry Smarr
The Sargasso Sea Experiment  The Power of Environmental Metagenomics ,[object Object],[object Object],[object Object],[object Object],MODIS-Aqua satellite image of ocean chlorophyll in the Sargasso Sea grid about the BATS site from 22 February 2003 J. Craig Venter, et al.  Science  2 April 2004: Vol. 304.  pp. 66 - 74
Evolution is the Principle of Biological Systems: Most of Evolutionary Time Was in the Microbial World Source: Carl Woese, et al You Are Here Much of Genome Work Has Occurred in Animals
Marine Genome Sequencing Project Measuring the Genetic Diversity of Ocean Microbes CAMERA will include  All Sorcerer II Metagenomic Data
Using the OptIPuter to Couple Data Assimilation Models  to Remote Data Sources Including Biology Regional Ocean Modeling System (ROMS)  http://ourocean.jpl.nasa.gov/ NASA MODIS Mean Primary Productivity  for April 2001 in California Current System
Announced January 17, 2006
Calit2’s Direct Access Core Architecture  Will Create Next Generation Metagenomics Server Traditional User Response Request Source: Phil Papadopoulos, SDSC, Calit2 + Web Services ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Flat File Server Farm W E B  PORTAL Dedicated Compute Farm (100s of CPUs) TeraGrid: Cyberinfrastructure Backplane (scheduled activities, e.g. all by all comparison) (10000s of CPUs)  Web (other service) Local  Cluster Local Environment Direct Access  Lambda Cnxns Data- Base Farm 10 GigE  Fabric
The Future Home of the Moore Foundation Funded Marine Microbial Ecology Metagenomics Complex First Implementation of  the CAMERA Complex Photo Courtesy Joe Keefe, Calit2 Major Buildout of Calit2 Server Room Underway
The Bioinformatics Core of the Joint Center for Structural Genomics will be Housed in the Calit2@UCSD Building Extremely Thermostable -- Useful for Many  Industrial Processes (e.g. Chemical and Food)  173 Structures (122 from JCSG) ,[object Object],[object Object],[object Object],[object Object],Source: John Wooley, UCSD
Interactive Visualization  of Thermatoga Proteins at Calit2 Source: John Wooley, Jurgen Schulze, Calit2
Calit2 and the Venter Institute Will Combine Telepresence with Remote Interactive Analysis Live Demonstration  of 21st Century  National-Scale  Team Science OptIPuter  Visualized  Data HDTV  Over  Lambda 25 Miles Venter Institute
Countries are Aggressively Creating Gigabit Services: Interactive Access to CAMERA Data System www.glif.is Created in Reykjavik, Iceland 2003 Visualization courtesy of Bob Patterson, NCSA.

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Creating a Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis (CAMERA)—Taking Metagenomics to Light Speed

  • 1. Creating a Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis (CAMERA)—Taking Metagenomics to Light Speed Invited Talk ONR Review Scripps Institution of Oceanography, UCSD June 27, 2006 Dr. Larry Smarr Director, California Institute for Telecommunications and Information Technologies Harry E. Gruber Professor, Dept. of Computer Science and Engineering Jacobs School of Engineering, UCSD
  • 2.
  • 3.
  • 4. OptIPuter Scalable Adaptive Graphics Environment (SAGE) Allows Integration of HD Streams Photo: David Lee, NCMIR, UCSD OptIPortal– Termination Device for the OptIPuter Global Backplane
  • 6.
  • 7. Evolution is the Principle of Biological Systems: Most of Evolutionary Time Was in the Microbial World Source: Carl Woese, et al You Are Here Much of Genome Work Has Occurred in Animals
  • 8. Marine Genome Sequencing Project Measuring the Genetic Diversity of Ocean Microbes CAMERA will include All Sorcerer II Metagenomic Data
  • 9. Using the OptIPuter to Couple Data Assimilation Models to Remote Data Sources Including Biology Regional Ocean Modeling System (ROMS) http://ourocean.jpl.nasa.gov/ NASA MODIS Mean Primary Productivity for April 2001 in California Current System
  • 11.
  • 12. The Future Home of the Moore Foundation Funded Marine Microbial Ecology Metagenomics Complex First Implementation of the CAMERA Complex Photo Courtesy Joe Keefe, Calit2 Major Buildout of Calit2 Server Room Underway
  • 13.
  • 14. Interactive Visualization of Thermatoga Proteins at Calit2 Source: John Wooley, Jurgen Schulze, Calit2
  • 15. Calit2 and the Venter Institute Will Combine Telepresence with Remote Interactive Analysis Live Demonstration of 21st Century National-Scale Team Science OptIPuter Visualized Data HDTV Over Lambda 25 Miles Venter Institute
  • 16. Countries are Aggressively Creating Gigabit Services: Interactive Access to CAMERA Data System www.glif.is Created in Reykjavik, Iceland 2003 Visualization courtesy of Bob Patterson, NCSA.