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HUMAN
REPRODUCTION
FEMALE REPRODUCTIVE SYSTEM
INTRODUCTION
Female reproductive system(front view)
Fallopian tubes are also called oviducts or uterine tubes
Female Reproductive organs
uterus
ovum
Female reproductive system-uterus and oviduct
Myometrium:
the middle
muscular layer
Ampulla: The part
of the fallopian tube
where fertilization
takes place.
Perimetrium: the
external membranous
structure
Femalereproductive system(side view)
Picture of pelvic region showing location of reproductive system
Picture showing the sectional view of female reproductive system
Ovary
Oviduct
Uterus
Cervix
Vagina
Urinary
bladder
Urethra
External genitals infemale-Vulva
INTERNAL STRUCTURE OF OVARY
Internal structure ofovary
Germinal epithelium- the lining of the ovary
These are a pair of ovoid
organs, located in the upper
pelvic cavity, one on each
side of the uterus.
Produce ovum and female
hormones
The ovum in the ovary
Potential eggs AT PUBERTY
The follicle rupture
after 2 weeks to
release the egg cell
The released egg
cell- OVULATION
A mature
follicle is
called
Graafian
follicle
Potential eggs surrounded by cells - follicle
Internal structure of ovary
Development of follicles
from primordial to graffian
follicle-
FOLLICULOGENESIS
Mature
follicle
Follicle cells produce
hormone ESTROGEN
Corpus luteum
produces
PROGESTERONE
The ovary produces the egg cell, in the
follicle.
MATURE GRAFFIAN FOLLICLE
MATURE GRAFFIAN FOLLICLE
STAINED GRAFFIAN FOLLICLE
At what age does the development of egg start in the female body?
Egg cell formation begins during the embryonic stage
6-7 Million immature
eggs.(5-6 months)
1-2 Million ( Birth)
4,00,000
(Puberty)
OOGENESIS
Inside the follicle-Oogenesis
• The formation of haploid
ovum from a diploid
oogonium is OOGENESIS.
• Oogenesis produces one
ovum and three polar bodies.
Oogenesis Spermatogenesis
Number of gametes
produced
One Four
Process begining Embryonic stage Puberty
Process ending Age of 45-50 Continues for life
time
Where does the
process occur
In the ovary In testis
Human ovum
• Cytoplasm is differentiated into
• Outer transparent exoplasm or egg cortex,
• Inner opaque endoplasm or ooplasm.
• Outer row of follicular cells surrounding
the egg cell –Corona radiata
• A glycoprotein layer inner to follicular
cells – zona pellucida.
• The membrane of the egg cell next to the
plasma membrane- vitelline membrane.
• Between the zona pellucida and the
vitelline membrane is the perivitelline
space.
• Where in the ovary does the egg cell develop?
• Inside the follicle
• How does the oocyte leave the ovary?
• The Graffian follicle ruptures to release the oocyte by ovulation.
• What happens to the ruptured follicle?
• It is converted to a yellow body called corpus luteum.
• In the ovary follicle cells produce estrogen and corpus luteum
produces progesterone.
• When does the production of egg cell begin in a female?
• During the embryonic development
Homologyof male and female reproductive organs
Male organs Female organs
Testis Ovary
Vas deferens Fallopian tube
Penis Clitoris
Fertilisation
For the zygote to develop into an embryo and then a baby the uterus
has to prepare itself.
The uterus thus undergoes changes to be able to nourish the
developing embryo.
MENSTRUAL CYCLE
PHASES IN MENSTRUAL CYCLE
Menstrualcycle- hormone function
PITUITARYFSH
Estrogen
Helps in proliferation/thickening of endometrium
LH
Progesterone
Helps in proliferation/thickening of endometrium and
maintaining pregnancy.
Follicle in ovary
Corpus luteum in ovary
Stimulates folliculogenesis Maintains corpus luteum
MENARCHE: The beginning of
the menstrual cycle.
It begins between 10-15 years.
MENOPAUSE: The end or
stopping of the menstrual cycle
It happens at 44-55years.
Menstrual cycle: phases
FOLLICULLAR PHASE
• It follows the menstrual phase and lasts for about 10-12
days.
• GnRH stimulates pituitary gland to release FSH.
• FSH stimulates the change ofa primary follicle of the ovary
into a Graffian follicle.
• Follicular cells secrete estrogens.
• Estrogens stimulate the growth, maintenance and normal
functioning of secondary sex organs.
• Uterine endometrium becomes thick, more vascular and
more glandular. The uterine glands become cork-screw
shaped and prepares itself for implantation
• Estrogen inhibit the secretion of FSH and stimulate the
secretion of LH.
• Gylcogen and fat accumulate in the endometrial cells.
OVULATORY PHASE
• It involves the ovulation from the Graffian follicle of ovary.
• It occurs midway between two menstrual cycles on 14th day of the onset of the
menstrual cycle.
• It is caused by increased level of LH in the blood.
• Ovum is received by the fimbriae of the Fallopian tube.
• LH also starts the change of empty Graffian follicle into corpus luteum.
• There is no much change in the uterine endometrium during ovulatory phase.
LEUTAL PHASE
• It lasts from 15th day to 28th day of the
menstrual cycle.
• Corpus luteum is formed and hence this
phase is called Leutal phase.
• Corpus luteum secretes progesterone
hormone.
• Decreases the secretion of FSH & LH.
• Uterine endometrium further proliferates
and is ready for implantation
MENSTRUAL PHASE
• It lasts about 3-5 days and extends from the 1st to 4th day of the menstrual
cycle.
• When ovum remains unfertilized the corpus luteum starts degenerating.
• The level of progesterone in the blood declines.
• The uterine tissues fails to be maintained.
• The unfertilized ovum along with ruptured uterine epithelium, about 50-100
ml of blood and mucus is discharged out and is called Menstrual flow or
Menstruation
CHANGES DURING MENSTRUAL
CYCLE
Changes in the ovary (recap)
The ovum or the egg cell develops inside the follicle in the ovary.
The mature or the graffian
follicle contains the
oocyte.
The graffian follicle
ruptures to release the
oocyte.
The process of release of the oocyte from
the graffian follicle in the ovary is called
OVULATION.
The ruptured follicle then forms a yellow body called CORPUS LUTEUM.
Changes in the uterus
While there are changes in the ovary, the uterus also shows changes.
1. The endometrial lining
starts to thicken
2. The lining thickens further
in expectation of the fertilised
egg cell
The thickening of the
endometrium is essential for
the implantation of the
fertilised egg cell
The estrogen from the follicle cells in the ovary acts on the endometrium.
Changes in the uterus
The shedding of the
uterine lining is called
MENSTRUATION
The released egg may get fertilised or it is not fertilised…thus..
If there is no fertilisation the
uterine lining is shed with the
unfertilised ovum.
If there is fertilisation the zygote
is attached to the wall and
pregnancy begins.
THE MENSTRUAL CYCLE
The series of events that occur in cyclic manner every 28-32 days and involve the
formation of female gamete with change in structure and function of entire female
reproductive system.
Hormones in the Menstrualcycle
Follicle stimulating hormone (FSH)
Luteinizing hormone (LH)
Oestrogen (produced by follicle cells)
Progesterone (produced by corpus luteum)
OVARY
Gonadotropins from anterior pituitary
HORMONAL CHANGES
ALONG WITH THE PHASES
OF MENSTRUAL CYCLE
EVENTS THAT OCCUR IN THE ENDOMETRIUM
ENDOMETRIUM
Hormonalchanges inMenstrual cycle:phases
ACCESSORY GLANDS
MAMMARY GLANDS
Mammary glands are tubulo-alveolar and
modified sweat glands.
15-20 lobes of milk glands
MAMMARY GLANDS
HORMONAL CONTROL
OESTROUS CYCLE
• The period of sexual responsiveness of female is called Oestrous Cycle or
heat period.
• It is generally for short duration.
• It is followed by anaestrous during which the female does not copulate
with male.
• Most of wild animals are Monoestrous (eg, sheep, deer, dog etc)
• Rats and mice breed as frequently as every five days and the guinea pig every
fifteen days so are Polyestrous.
THANK YOU

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Human Reproduction - II

  • 3. Female reproductive system(front view) Fallopian tubes are also called oviducts or uterine tubes
  • 5. Female reproductive system-uterus and oviduct Myometrium: the middle muscular layer Ampulla: The part of the fallopian tube where fertilization takes place. Perimetrium: the external membranous structure
  • 6. Femalereproductive system(side view) Picture of pelvic region showing location of reproductive system Picture showing the sectional view of female reproductive system Ovary Oviduct Uterus Cervix Vagina Urinary bladder Urethra
  • 9. Internal structure ofovary Germinal epithelium- the lining of the ovary These are a pair of ovoid organs, located in the upper pelvic cavity, one on each side of the uterus. Produce ovum and female hormones
  • 10. The ovum in the ovary Potential eggs AT PUBERTY The follicle rupture after 2 weeks to release the egg cell The released egg cell- OVULATION A mature follicle is called Graafian follicle Potential eggs surrounded by cells - follicle
  • 11. Internal structure of ovary Development of follicles from primordial to graffian follicle- FOLLICULOGENESIS Mature follicle Follicle cells produce hormone ESTROGEN Corpus luteum produces PROGESTERONE The ovary produces the egg cell, in the follicle.
  • 15. At what age does the development of egg start in the female body? Egg cell formation begins during the embryonic stage 6-7 Million immature eggs.(5-6 months) 1-2 Million ( Birth) 4,00,000 (Puberty)
  • 17. Inside the follicle-Oogenesis • The formation of haploid ovum from a diploid oogonium is OOGENESIS. • Oogenesis produces one ovum and three polar bodies.
  • 18. Oogenesis Spermatogenesis Number of gametes produced One Four Process begining Embryonic stage Puberty Process ending Age of 45-50 Continues for life time Where does the process occur In the ovary In testis
  • 19. Human ovum • Cytoplasm is differentiated into • Outer transparent exoplasm or egg cortex, • Inner opaque endoplasm or ooplasm. • Outer row of follicular cells surrounding the egg cell –Corona radiata • A glycoprotein layer inner to follicular cells – zona pellucida. • The membrane of the egg cell next to the plasma membrane- vitelline membrane. • Between the zona pellucida and the vitelline membrane is the perivitelline space.
  • 20. • Where in the ovary does the egg cell develop? • Inside the follicle • How does the oocyte leave the ovary? • The Graffian follicle ruptures to release the oocyte by ovulation. • What happens to the ruptured follicle? • It is converted to a yellow body called corpus luteum. • In the ovary follicle cells produce estrogen and corpus luteum produces progesterone. • When does the production of egg cell begin in a female? • During the embryonic development
  • 21. Homologyof male and female reproductive organs Male organs Female organs Testis Ovary Vas deferens Fallopian tube Penis Clitoris
  • 22. Fertilisation For the zygote to develop into an embryo and then a baby the uterus has to prepare itself. The uterus thus undergoes changes to be able to nourish the developing embryo.
  • 25. Menstrualcycle- hormone function PITUITARYFSH Estrogen Helps in proliferation/thickening of endometrium LH Progesterone Helps in proliferation/thickening of endometrium and maintaining pregnancy. Follicle in ovary Corpus luteum in ovary Stimulates folliculogenesis Maintains corpus luteum MENARCHE: The beginning of the menstrual cycle. It begins between 10-15 years. MENOPAUSE: The end or stopping of the menstrual cycle It happens at 44-55years.
  • 27. FOLLICULLAR PHASE • It follows the menstrual phase and lasts for about 10-12 days. • GnRH stimulates pituitary gland to release FSH. • FSH stimulates the change ofa primary follicle of the ovary into a Graffian follicle. • Follicular cells secrete estrogens. • Estrogens stimulate the growth, maintenance and normal functioning of secondary sex organs. • Uterine endometrium becomes thick, more vascular and more glandular. The uterine glands become cork-screw shaped and prepares itself for implantation • Estrogen inhibit the secretion of FSH and stimulate the secretion of LH. • Gylcogen and fat accumulate in the endometrial cells.
  • 28. OVULATORY PHASE • It involves the ovulation from the Graffian follicle of ovary. • It occurs midway between two menstrual cycles on 14th day of the onset of the menstrual cycle. • It is caused by increased level of LH in the blood. • Ovum is received by the fimbriae of the Fallopian tube. • LH also starts the change of empty Graffian follicle into corpus luteum. • There is no much change in the uterine endometrium during ovulatory phase.
  • 29. LEUTAL PHASE • It lasts from 15th day to 28th day of the menstrual cycle. • Corpus luteum is formed and hence this phase is called Leutal phase. • Corpus luteum secretes progesterone hormone. • Decreases the secretion of FSH & LH. • Uterine endometrium further proliferates and is ready for implantation
  • 30. MENSTRUAL PHASE • It lasts about 3-5 days and extends from the 1st to 4th day of the menstrual cycle. • When ovum remains unfertilized the corpus luteum starts degenerating. • The level of progesterone in the blood declines. • The uterine tissues fails to be maintained. • The unfertilized ovum along with ruptured uterine epithelium, about 50-100 ml of blood and mucus is discharged out and is called Menstrual flow or Menstruation
  • 32. Changes in the ovary (recap) The ovum or the egg cell develops inside the follicle in the ovary. The mature or the graffian follicle contains the oocyte. The graffian follicle ruptures to release the oocyte. The process of release of the oocyte from the graffian follicle in the ovary is called OVULATION. The ruptured follicle then forms a yellow body called CORPUS LUTEUM.
  • 33. Changes in the uterus While there are changes in the ovary, the uterus also shows changes. 1. The endometrial lining starts to thicken 2. The lining thickens further in expectation of the fertilised egg cell The thickening of the endometrium is essential for the implantation of the fertilised egg cell The estrogen from the follicle cells in the ovary acts on the endometrium.
  • 34. Changes in the uterus The shedding of the uterine lining is called MENSTRUATION The released egg may get fertilised or it is not fertilised…thus.. If there is no fertilisation the uterine lining is shed with the unfertilised ovum. If there is fertilisation the zygote is attached to the wall and pregnancy begins.
  • 35. THE MENSTRUAL CYCLE The series of events that occur in cyclic manner every 28-32 days and involve the formation of female gamete with change in structure and function of entire female reproductive system.
  • 36. Hormones in the Menstrualcycle Follicle stimulating hormone (FSH) Luteinizing hormone (LH) Oestrogen (produced by follicle cells) Progesterone (produced by corpus luteum) OVARY Gonadotropins from anterior pituitary
  • 37. HORMONAL CHANGES ALONG WITH THE PHASES OF MENSTRUAL CYCLE
  • 38. EVENTS THAT OCCUR IN THE ENDOMETRIUM
  • 42. MAMMARY GLANDS Mammary glands are tubulo-alveolar and modified sweat glands. 15-20 lobes of milk glands
  • 45.
  • 46. OESTROUS CYCLE • The period of sexual responsiveness of female is called Oestrous Cycle or heat period. • It is generally for short duration. • It is followed by anaestrous during which the female does not copulate with male. • Most of wild animals are Monoestrous (eg, sheep, deer, dog etc) • Rats and mice breed as frequently as every five days and the guinea pig every fifteen days so are Polyestrous.

Notas del editor

  1. Consists of Pair of ovaries Fallopian tubes (oviducts) Uterus Cervix Vagina Accessory glands
  2. Vulva includes- 1. The lip-like structures (labia majora and labia minora) around the vagina. The labia majora protects the inner parts. 2. Clitoris: A small protrusion of tissue covered with a thin flap of tissue. The clitoris is the main source of sensations during sexual activity.
  3. Cortical stroma- the outer layer of ovarian tissue containing round structures containing the ovum. Medullary stroma- the inner layer of ovarian tissue consisting of neuro-vascular tissue.