Codefresh is a Kubernetes-native CI/CD product used by 20,000 users globally. The document discusses using Codefresh to build a CI/CD pipeline across multiple Kubernetes clusters in different clouds or regions. This provides high availability and allows mitigating outages by failing over workloads between clusters. It also demonstrates using Istio for a canary deployment process, deploying a new version to a percentage of traffic initially and then routing all traffic to it if everything works as expected.