The company founder effectively life-hacked a $billion dollar OTC product and was awarded 6 patents for it. The funds raised were to prove efficacy and will probably be the only funding required before licensing. We took a highly technical breifing and created a story that is both understandable and informative. We developed the brands, strategy, copy, graphics, and put together the deck and arranged key meetings with investors. www.wildoutwest.com

1. 100M people in the US suffer from a
problem for which we have a strong
solution. The patents are issued, we
are raising funds for FDA trial...
PAXEROL™ for NOCTURIA
07.21.2014

2. Misery associated with nocturia
Insomnia, fatigue, depression,
lower quality of life
US lost work time $60B/year
Incontinence care currently 25%
of the costs of nursing home care
Heart disease, stroke, brain
damage, hip fractures
NOCTURIA is the #1 urology
complaint of men and women 55-84
65%of people
ages 55-84
100Msufferers in US
(2.2B worldwide)
THIS IS A SIGNIFICANT UNMET MEDICAL NEED AS NO CURRENT
DRUG TREATS LOW NOCTURNAL BLADDER CAPACITY
2

3. Paxerol is a unique 8 hour extended release formulation
that provides increased nocturnal bladder capacity (NBC)
through the night. (+50-100%)
HOW IT WORKS: For 76% of people suffering from nocturia,
low NBC is a key issue. The cause is excess Prostaglandins
(PGE2) that irritate the bladder.
For sufferers of Nocturia and Over Active Bladder, a
combination of APAP & ibuprofen will inhibit PGE2
production to increase comfortable bladder capacity.
People are informally using the combination of already
approved drugs. It is proving effective for 80%. Our next step
is to prove efficacy in trials. Our use of these drugs for this
purpose and the addition of the timed release aspect are
protected by numerous broad patents.
3
INTRODUCING
APAP
ibuprofen
+ time release
Paxerol has three synergistic
mechanisms of action.

4. SCIENTIFIC ADVISORS
Frank Rauscher, III, Ph.D., Chief Scientist: Dep. Director, Wistar Inst.
Khurshid Iqbal, Ph.D., Pharma Chemist, J&J, Hoffmann-LaRoche
LEADING CLINICAL EXPERTS
Tony DelConte, MD, led Novartis Enablex FDA trials
Thomas Garvey III, MD, NIH, FDA, drug safety expert
LICENSING AND LEGAL
Joy Barton, Ph.D., Novartis, Licensing Agent
Ed Allera, Buchanan Ingersoll, FDA Focused Lawyer
Ping Wang MD IP Medical Expert Andrews Kurth, (named top 1000 patent Lawyer)
4
World Class Team
David Dill, CEO, IBM, CFO of 7 firms, 35 years as manager

5. 6 Patents issued in 2012-2014 (16+ year life)
• Method of use claims; broad spectrum combinations.
• Covers use with Over Active Bladder (OAB)
• Extended release critical: 2-3 hour half life standard
• Wide range dosing of APAP with antimuscarinics, diuretics, antidiuretics,
spasmolytics, and/or NSAIDs.
• PCT process for worldwide protection filed 12/2010
5
Intellectual Property
8,236,857 B2 – Extended-release formulation
8,236,856 B2 – Delayed release formulation
8,685,453 B2 – Low dose APAP and NSAIDs
8,445,015 B2 – Extended-release formulation
8,445,011 B2 – Delayed-release formulation
8,703,184 B2 – Delayed-release formulation
US PATENTS ISSUED:

6. 6
Vesicare, Enablex, Myrbetriq
• Effects often take months
• Large % do not respond
• Severe side effects
• 43–83% stop in < 30 days
• 10-15% fewer bathroom trips
• Treats annoying problem
• Significant competition
OVERACTIVE BLADDER DRUGS
2M
patients
(0.1%)
$2B
SALES
• Effects in as little as 30 mins.
• 80% positive (anecdotal)
• No side effects
• 20% drop out (anecdotal)
• 33-100% fewer nightly trips
• Treats dangerous problem
• No current competition
$2-8B
SALES ?
Proving effective for
OAB, but focused
on treatment of
bladder problems
related to sleep

7. 7
Actionable Market
$2-8B
SALES
2018
Paxerol is a new product that is effective in ways that current OAB
(over active bladder) products are not.
*source 2013 Report by Debra E. Irwin et al / Company estimates
NOT A
SIGNIFICANT
PROBLEM
1 x per night
1.2 Billion
423 Million
Unaffordable
600 Million
130 Million No efficacy
50 Million Medical Issues
$0.30 / dose/daily = $39B
annual sales potential (retail)
NOTE: Forecasting a new market is
highly speculative.
2.4 Billion sufferers
es'mated
by
2018

8. Almost all regulatory bodies outside US permit use of unlicensed drugs
(“Specials”). We have an agreement for such distribution of Paxerol.
Contract signed April 2014 (Q1 2015 launch) with Ethicor Pharma, Ltd. (UK). Plan
to launch Paxerol with support of key opinion leaders, education sessions, and
published articles. Partnered with UDG, UK’s largest prescription drug distributor.
Ethicor exits when big pharma enters markets.
Top end price target – $5/dose controlled by Ethicor
Gross profit estimate – 98%
Only ages 60+, EU, MENA, and SA, with no advertising
8
Ethicor Short-term Revenues
2015 2016 2017 2018 2019 TOTAL
$832 $6,611 $26,949 $50,538 $73,161 $151,091
$k Ethicor Projected Income

9. We have protocol feedback and indications of interest from key
global pharmaceutical leaders.
Licensee to complete trials, patents, and launch Paxerol. We are expecting an
upfront payment after Phase 2 trial (mid-2015), milestone payments, 15% royalty.
9
Big Pharma License

10. Safe Drug, low risk Huge unmet need.
Tight patent barrier through 2030
10
Strengths of This Investment
This is not a new chemical entity. Approval can be attained
with a simpler, relatively inexpensive trial: Avoids Phase 1 Trial
safety tests, and years of risk from unexpected side effects.
Strong Ethicor validation. International sales begin before trial
completion, mitigates risk. Mid-2015 worldwide big pharma license.
Strong ROI @ up to 94% net profit.
$3M to positive Cash flow 12-15 months
1
2
3
4
5
$787K raised so far primarily through pooled
due diligence of Keiretsu Forum.

11. 11
Use of Funds
Primary use of funds will be in the management of the trial
process and preparations for Ethicor launch.
Ethicor GP Rev Share
Expenses
Mfg. Testing
Clinical Trials
Business Dev.
Patents/ Legal WW
G&A / other
TOTAL Expenses
Net Income
2014 Q1 Q2 Q3
$42 $125 $221
$500 – – –
$612 $425 – –
$108 $29 $33 $38
$396 $130 $130 $90
$475 $55 $50 $50
$2,095 $639 $213 $178
($2,095) ($597) ($88) $43
Figures expressed as $k
2015
Profits in Q3 2015

12. 12
Projections
Ethicor GP Rev Share
Big Pharma Milestones
Big Pharma Royalties
TOTAL Revenue
Expenses
Net Income
%
2014 2015 2016 2017 2018 2019 2020 2021
$1 $7 $27 $51 $73
– $13 $5 $5 $38
– – – – $15 $77 $307 $768
$0 $13 $12 $32 $103 $150 $307 $767
$2 $2 $1 $2 $6 $8 $16 $39
($2) $11 $11 $30 $97 $142 $291 $729
– 84% 92% 94% 95% 95% 95% 95%
Figures $Millions
Key Assumptions
1. FDA approval 2018 (no accelerated approval designation)
2. $0.30 retail ($0.15 wholesale) in 2018
3. 15% License fee (15-18% tiered structure would add $120M in 2021)
4. Licensing Agent 5% fee
5. A $5B big pharma drug by 2021 (no OAB or bedwetting solution)

13. Patents filed (issued 2012, 2013, & 2014)
FDA Confirms no Phase 1 safety tests required
EU“Special”Ethicor contract (launch Q1/2015)
Series A complete and trial contract signed
1st patient starts trial:
13 week crossover design; patients with 3+ voids/night
60 patient trial completed.
Sign big pharma license (Series A cash back)
FDA approval H1- Paxerol launch 6 weeks later
13
Milestones
7/2010
4/2012
4/2014
Q3/2014
Q2/2015
Q3/2015
2018
Q1/2015

14. • 22 patients informally tested Paxerol for a Johns Hopkins physician.
17 reported good results (fewer nightly bathroom trips). (77%)
• 18 patients have since tested Paxerol, with 15 reporting good results
(1-4 fewer nightly bathroom trips).
• Placebo effects are always possible, but much less likely when sleeping.
• 32 of 40 patients (80%) self-report success – without placebo controls.
• 3 articles report OAB suffers’urine averages 700% higher PGE2 levels -
Paxerol addresses PGE2 levels.
14
Anecdotal Evidence

15. Independent clinical studies consistently report that ~70% of nocturia patients
experience improvement when taking appropriate doses of certain NSAIDs
80% of patients with neurogenic bladder and 74% of patients with BPH
experience improvement in nocturia when taking appropriate doses of NSAIDs
(consistent with animal studies)
Johns Hopkins proves NSAIDs reduce bladder spasms
Ohio State preclinical model of bladder function showed acetaminophen equal
to NSAIDs in reducing inflammation, achieved through independent
mechanisms of action
Together acetaminophen and NSAIDs impact multiple independent molecular
pathways to relieve nocturia symptoms
15
Supporting Research

16. No matter how nice
your bathroom is, nobody wants
to visit in the middle of the night

17. 17
OAB Market Segment
$2.1B
SALES
2011
*source 2013 Report by Debra E. Irwin et al / Company estimates
Astellas
VesiCare
3.8M
1.6 M Enablex
In the 12 months ending January 2012, more than 17.8 million
prescriptions were filled for drugs in the Over Active Bladder,
accounting for almost $2.1 billion in sales.
Oxybutynin
3.7M
Oxybutynin
ER 3.6M
Pfizer
Detrol LA
3.3 M
712 k Pfizer Toviaz

18. 18
A Serious Problem
* Results from the Third National Health and
Nutrition Examination Study
12 year survival odds for
women ages 65-90 based on
nightly voiding episodes:
0 voids 68%
1 void 60%
2 voids 50%
3+ voids 22%
Association of Nocturia and
Mortality: Results From the
Third National Health and
Nutrition Examination Study

19. 19
Clinical Trial Design
Inclusion Criteria
• Those who use bathroom 3+ times/night
• Those with elevated PGE2 levels
Exclusion Criteria
• Congestive heart failure, diabetes, etc.
• Those with major arthritis or muscle pains
13 week double blind crossover study
• Each patient tests all alternatives (to normalize variables)
• Paxerol, APAP, ibuprofen, placebo
• Show Paxerol’s superiority in reducing nocturia
• Delay time to first awakening
• Improve quality of life

20. 20
Series A vs Series B
Both share 50% of returns until made whole for initial investment
Series A thereafter gets returns based on $1.10/share
Series B gets 50% until 15X invested $ back (1-4 years)
Inflated returns come from Founders, not Series A
Series B thereafter get returns based on $2.20/share