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Machine Learning in Bioinformatics

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Dmytro Fishman
Dmytro Fishman

Bioinformatics is a science of extracting knowledge from biological data, сomplexity and amount of which, has increased significantly over the past decades. To meet the challenges ahead, more sophisticated algorithms and assets should be adopted. Thus, Machine Learning has become an everyday tool in Bioinformatics, that helps to solve important biological riddles. In this report, In this presentation I discussed examples of how using well-known Machine Learning methods, bioinformaticians and computer scientists help doctors and biologists diagnose and treat deadly diseases.

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Machine Learning in Bioinformatics Dmytro Fishman (dmytro@ut.ee) BIIT
Dmytro Fishman E-mail: dmytro@ut.ee Oct 21 - 23, Tartu
Machine Learning in Bioinformatics
Machine Learning in Bioinformatics
https://siteman.wustl.edu/glossary/cdr0000046470/
Central dogma
Microlevel http://learn.genetics.utah.edu/content/cells/scale/
What these books contain?
This is a single human genome ~4GB
Big Data
ML in Bioinformatics (part III) 2016
Labs that produce data Research groups that can analyse data
What is Bioinformatics? “Bioinformatics is an interdisciplinary field that develops methods and software tools for extracting knowledge from biological data.” https://en.wikipedia.org/wiki/Bioinformatics
What is Bioinformatics? “Bioinformatics is • an interdisciplinary field • develops methods and software tools • for extracting knowledge from biological data.”
What is Bioinformatics? Presenting this knowledge to non-experts “Bioinformatics is • an interdisciplinary field • develops methods and software tools • for extracting knowledge from biological data.”
Bioinformatics Computer Science Biology Statistics
Bioinformatics Computer Science Biology Statistics
Bioinformatics Computer Science Biology Statistics P-hacking
Machine Learning in Bioinformatics
Feature#2 Feature #1
Feature#2 Feature #1
Feature#2 Feature #1
Feature#2 Feature #1 Healthy Sick
Feature#2 Feature #1 Healthy Sick Feature#2 Feature #1
Feature#2 Feature #1 Healthy Sick Feature#2 Feature #1
Feature#2 Feature #1 Healthy Sick Feature#2 Feature #1 Anything in common?
Feature#2 Feature #1 Healthy Sick Feature#2 Feature #1 Females Males
Feature#2 Feature #1 Healthy Sick Feature#2 Feature #1 Females Males Supervised Learning Unsupervised Learning
Linear Classifiers Decision Trees Feature #1 > 20 <= 20 Feature #2 > 1000 <= 1000 1 Neural Networks Input Hidden Layer 0 k-Nearest Neighbors Others Self-Organizing Map https://topepo.github.io/caret Many more Feature#2 Feature #1 Output Layer 1 0 1 1
Machine Learning in Bioinformatics
Anna, 32, Female, DT2,… Metadata
Anna, 32, Female, DT2,… Medical Signal Metadata
Anna, 32, Female, DT2,… Medical Signal Metadata Medical Imaging
Anna, 32, Female, DT2,… Medical Signal Metadata Medical Imaging
Anna, 32, Female, DT2,… Medical Signal Metadata Medical Imaging Clinical Data
Anna, 32, Female, DT2,… ACCTTGCTTACC… Medical Signal Metadata Medical Imaging Clinical Data Genetical Information
Anna, 32, Female, DT2,… ACCTTGCTTACC… Medical Signal Metadata Medical Imaging Clinical Data Genetical Information
Metabolite #1 Metabolite #2 Metabolite #3 First individual
Metabolite #1 Metabolite #2 Metabolite #3 First individual M1 M2 M3
Metabolite #1 Metabolite #2 Metabolite #3 First individual M1 M2 M3
Metabolite #1 Metabolite #2 Metabolite #3 Second individual M1 M2 M3
Metabolite #1 Metabolite #2 Metabolite #3 Individual #N M1 M2 M3
Metabolite #1 Metabolite #2 Metabolite #3 M1 M2 M3 Patients Healthy Individual #N
Metabolite #1 Metabolite #2 Metabolite #3 M1 M2 M3 Patients Healthy Individual #N
Metabolite #1 Metabolite #2 Metabolite #3 M1 M2 M3 Patients Healthy P(disease) = 0.6*M1 + 0*M2 - 0.7*M3 Individual #N
Metabolite #1 Metabolite #2 Metabolite #3 M1 M2 M3 Patients Healthy P(disease) = 0.6*M1 + 0*M2 - 0.7*M3 Individual #N
Dima
Anna, 32, Female, DT2,… ACCTTGCTTACC… Medical Signal Metadata Medical Imaging Clinical Data Genetical Information
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N …
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … Human genomes are 99.5% similar
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … Mutations
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … Deletions
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … Insertions
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … Compute pairwise distance
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … Compute pairwise distance #1 #2 … #N #1 0 29 … 34 #2 29 0 … 56 … … … … … #N 34 56 … 0 Distance Matrix
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … #1 #2 … #N #1 0 29 … 34 #2 29 0 … 56 … … … … … #N 34 56 … 0 Distance Matrix
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … #1 #2 … #N #1 0 29 … 34 #2 29 0 … 56 … … … … … #N 34 56 … 0 Distance Matrix PCA
…AACCTTTACATTAAACTGGGACCCGG… Individual #1 …AACCTTTACATTATACTGGGAGCCGG… Individual #2 …CTAAACCACATTATACTGGGACCCGG… Individual #N … #1 #2 … #N #1 0 29 … 34 #2 29 0 … 56 … … … … … #N 34 56 … 0 Distance Matrix PCA Principal component analysis of the combined autosomal genotypic data of individuals from Russia and seven European countries (Finnland, Estonia, Latvia, Poland, Czech Republic, Germany [5] and Italia [22]). Khrunin et al.
Anna, 32, Female, DT2,… ACCTTGCTTACC… Medical Signal Metadata Medical Imaging Clinical Data Genetical Information
Neuroimaging
Neuroimaging EEG Signal
Neuroimaging EEG Signal Fourier Transform Data
Neuroimaging EEG Signal Data
Neuroimaging EEG Signal Data Machine Learning
Neuroimaging EEG Signal Data Machine Learning P( ) = .92
Neuroimaging EEG Signal Data Machine Learning P( ) = .92 Flying
Neuroimaging EEG Signal Data Machine Learning P( ) = .92 Soft Introduction to Brain-Computer Interfaces by Ilya Kuzovkin (www.ikuz.eu) Flying
Cardiogram Data Machine Learning P( ) = .92 Cardiograph
Anna, 32, Female, DT2,… ACCTTGCTTACC… Medical Signal Metadata Medical Imaging Clinical Data Genetical Information
AD NDC Alzheimer’s Disease
Disease Stage Prediction Diabetic Retinopathy AD NDC Alzheimer’s Disease
Disease Stage Prediction Diabetic Retinopathy Alzheimer’s Disease Heart Volume Prediction Heart Failure AD NDC
Disease Stage Prediction Diabetic Retinopathy Mitotic Cells Count Breast Cancer Alzheimer’s Disease Heart Volume Prediction Heart Failure AD NDC
AD NDC Alzheimer’s Disease Disease Stage Prediction Diabetic Retinopathy Heart Volume Prediction Heart Failure Mitotic Cells Count Breast Cancer Stained Cells Count Cancer
AD NDC Alzheimer’s Disease Disease Stage Prediction Diabetic Retinopathy Heart Volume Prediction Heart Failure Mitotic Cells Count Breast Cancer Stained Cells Count Cancer Protein Classification
AD NDC Alzheimer’s Disease Disease Stage Prediction Diabetic Retinopathy Heart Volume Prediction Heart Failure Mitotic Cells Count Breast Cancer Stained Cells Count Cancer Protein Classification Accurate classification of protein subcellular localization from high throughput microscopy images using deep learning. Pärnamaa et al.
Anna, 32, Female, DT2,… ACCTTGCTTACC… Medical Signal Metadata Medical Imaging Clinical Data Genetical Information
National Health System peterson@nhs.eu Log In Having trouble logging in?
Anna, 32, Female see full profile see all recent scans see all genetic risks Susceptible to DT2 09 10 11 12 0102 0304 normal Sugar 2010 2011 2011 see other tests results Enter symptoms here… 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016 Birth A37: Whooping cough J21.8: Acute bronchiolitis S82: Fracture of lower leg V22.0: Normal Pregnancy Dr. Peterson related medical reports Logout
Anna, 32, Female, DT2,… ACCTTGCTTACC… Data Integration for better decision making is the key challenge
Quiz
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes are us… and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY— EUROPEAN,BIOINFORMAT,ICS,INSTITUTE 50%
MEETUP
BIIT dmytro@ut.ee
Machine Learning in Bioinformatics

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