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Child Psychiatry – Part 1
Dr Bhakti Murkey
Assistant Professor, Department of Psychiatry (PMCH Udaipur)
Outline
 Classification (ICD-10)
 History taking in Child Psychiatry
 ADHD
 Autism
 Asperger’s Syndrome
 Intellectual Disability Disorder
 Specific Learning Disorders
 Tic Disorder
 Disruptive Behavior Disorders
 Oppositional Defiant Disorder
 Conduct Disorder
 Anxiety Disorders in children
 Childhood Depression
 Childhood Mania
 Childhood onset Schizophrenia
 Elimination Disorders
 Rating Scales in children
 References
Classification of Childhood Psychiatric Disorders
(ICD-10)
 F 70-73: Mental Retardation
 F 80-83: Specific Developmental Disorders
 F 84: Pervasive Developmental Disorder
 F 90: Hyperkinetic Disorder
 F 91: Conduct Disorder
 F 93: Emotional Disorders with childhood onset
 F 94: Disorders of social functioning
 F 95:Tic Disorder
History Taking in Child Psychiatry
 Chief complaints
 History of Present Illness
 Past History
 Personal History
 Medication History
 Family History
 Social History
 Childhood History
Childhood History
 Pregnancy
 Perinatal history: birth asphyxia? LBW? NICU stay? Major medical/ surgical illness?
 Developmental milestones: gross and fine motor, social and language
 Behavioral symptoms: temper tantrums, head-banging, thumb-sucking, regressive
behavior, stereotypy?
 Schooling history: behavior, performance at school, any complaints? Relationship
with peers?
 Assessment of Temperament
Temperament Assessment Scale
Temperament Assessment Scale
Childhood History contd…
 Family environment
 Parenting styles
 Relationship with sibling/s
 Any major life events or recent stressor (for example, death of pet or
change in school, etc)
 Feeding and sleep patterns
 Indulgence in substance use
Effect of Maternal Depression
Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder
 Impairment in attention and/or hyperactivity-impulsivity
 In at least 2 settings
 Interfering with developmentally appropriate functioning (social, academic or
extracurricular)
 For at least 6 months
 1-2% prevalence
 3 times more common in boys
 Genetic vulnerability
 DA and NA dysfunction in prefrontal cortex
 Up to 50% children will have other co-morbid psychiatric illnesses
Attention Deficit Hyperactivity Disorder
 Up to15% of cases continue to meet diagnostic criteria for ADHD at the age of
25 years
 50% of individuals will suffer some impairment from residual symptoms
 5 times greater risk for antisocial behavior, substance abuse and other
psychiatric disorders
 15-20% develop substance misuse problems
 Poor prognosis if early stressful life experiences (poverty, overcrowding,
expressed emotions and parental psychopathology) or severe symptoms,
predominantly hyperactive - impulsive and associated with conduct, language
or learning disorder
Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder
Autism Spectrum Disorder
(Pervasive Developmental Disorders)
Autism Spectrum Disorder
(Pervasive Developmental Disorders)
 PDD is an umbrella term, which includes Autism, Asperger’s syndrome,
Rett’s syndrome and Childhood Disintegrative Disorder
 Characterized by: impaired reciprocal social interactions, communication
difficulties, aberrant language development, and restricted behavioral
repertoire
 Typically emerge before the age of 3 years
 Four times more frequent in boys
 There is no cure or treatment for autism
 Early and effective management is desirable for a better outcome, and
involves a comprehensive assessment of the child and family’s needs
Autism Spectrum Disorder
(Pervasive Developmental Disorders)
 Management aimed at helping the family, providing vocational training and
support to the person
 Psychotherapy may be helpful for verbal skills
 Specific intervention programmes:
 Applied Behavior Analysis program: based on operant conditioning, imitation
and reinforcement
 TEACCH – Treatment and Education for Autistic and related Communication
Handicapped Children program: based on the belief that children are
motivated to learn language, successful in reducing self injurious behaviors
and enhancing life skills
Autism Spectrum Disorder
(Pervasive Developmental Disorders)
 Pharmacotherapy commonly used as adjunct
 SSRIs - most widely used for restricted repetitive behaviors
 Second generation antipsychotics are the first line treatment for associated
irritability and aggression
 The only licensed medication is Risperidone (0.5 – 2 mg/day)
Asperger’s Syndrome
 Same type of qualitative abnormalities in reciprocal social interaction that
typify autism with a restricted, stereotyped and repetitive, repertoire of
behavior/interests
 IQ and language are usually within normal limits
 No significant delays occur in relation to language development., cognitive
development, and/or age appropriate self help skills
 One third as common as autism with a prevalence of about 6 in 10,000
 Normal IQ and high level social skills have good prognosis
Rett’s Syndrome
 Rare X linked dominant disorder
 Almost exclusively affects females
 Head circumference normal at birth
and developmental milestones
unremarkable in early life
 Between 6-18 months, head
growth begins to decelerate and
produces microcephaly
 Loss of purposeful hand
movements
 Stereotypic hand wringing
 Loss of previously acquired speech
 Psychomotor retardation and
ataxia
 Both receptive and expressive
communicative and social skills
plateau
 Poor muscle coordination
 Unsteady gait
 Associated seizures in up to 75%
cases
 Irregular respiration, with episodes
of hyperventilation, apnoea and
breath holding
Childhood Disintegrative Disorder
 Heller’s disease
 Marked regression in several areas of functioning after at least 2 years of
apparently normal development
 Loss of acquired motor, language, and social skills between ages 3 and 4 years
 Loss of skills in two of the following areas: language, social or adaptive behavior;
bowel or bladder control, play and motor skills
 Abnormality in at least two of the following categories: reciprocal social interaction,
communication skills, and stereotyped or restricted behavior
 Associated seizure disorder
 Male predominance
 Poor prognosis
Mental Retardation
(Intellectual Disability Disorder)
Mental Retardation
(Intellectual Disability Disorder)
 Developmental disability marked by lower-than-normal intelligence and
limited daily living skills
 Either normally present at birth or develops early in life
 Types:
 Borderline intelligence IQ < 80
 Mild (IQ = 50-70)
 Moderate (IQ = 35-50)
 Severe (IQ = 20-35)
 Profound (IQ < 20)
Mental Retardation
(Intellectual Disability Disorder)
 Mild MR:
 Individuals can often live on their own with community support
 They have minimum retardation in sensory-motor areas
 Moderate MR:
 They are challenged academically and often are not able to achieve
academically above a second to third grade level
 As adults, they may be able to perform semiskilled work under appropriate
supervision
Mental Retardation
(Intellectual Disability Disorder)
 Severe MR:
 Individuals can often master the most basic skills of living, such as
cleaning and dressing themselves
 Is often recognized early in life with poor motor development & absent or
markedly delayed speech & communication skills
 Profound MR:
 Individuals can often develop basic communication and self-care skills
 Most individuals have identifiable causes for their condition
Mental Retardation
(Intellectual Disability Disorder)
 Causes:
 Infections (present at birth or occurring after birth)
 Chromosomal abnormalities:
 Chromosome deletions
 Defects in chromosomal inheritance
 Errors of chromosome numbers
 Problems at birth:
 Difficult labor or perinatal hypoxia
 Problems during pregnancy (TORCH infection)
 Exposure to certain toxins/ teratogenic medication
SpLD
(Specific Learning Disability)
 Problems with educational achievements
 Performance significantly below that expected for IQ or age
 Under-achievement in reading, written expression, or mathematics
 Genetic predisposition, peri-natal injury and neurological and other medical
conditions can contribute
 Affect at least 5% of school age children
 Associated with up to 50% risk of co-morbid disorders, including ADHD,
communication disorders, conduct disorders and depression
 Commonly present as emotional or behavioral problems
 Strong evidence of heritability
Tic Disorder (Tourette Syndrome)
Tic Disorder (Tourette Syndrome)
 Multiple motor and/ or vocal tics
 Present for at least a year
 Significant distress and impaired function
 Facial tics: eye blinks or head jerks are often the initial symptoms, but tics
involving the neck, shoulders, and upper extremities are also common
 Vocal tics begin 1- 2 yrs after the onset of motor symptoms and range from
meaningless sounds to clear words
 Vocal tics are crucial for diagnosis and may be barks, hisses, hoots and not
necessarily obscene blasphemous utterances (coprolalia), echolalia, or
palilalia(repeating ones own speech)
 Treatment: low dose Anti-psychotics (Haloperidol/ Risperidone)
Oppositional Defiant Disorder
Oppositional Defiant Disorder
 Enduring pattern of negative, hostile, disobedient and defiant behavior, without
serious violations of societal norms or the rights of others
 For at least 6 months
 Temper outbursts, active refusal to comply with rules, tendency to blame
others, spiteful and annoying behaviors
 Can begin as early as 3 years of age, typically noted by 8 years
 Prevalence 2-5%
 More prevalent in boys than in girls
 25% cases show no symptoms in later life but many progress to conduct
disorder
Oppositional Defiant Disorder
 Aetiology: temperamental factors like sick or traumatized child and power
struggle between parents & child
 ADHD in early life is a predictor of oppositional defiant disorder and conduct
disorder later in life
 Almost always interferes with interpersonal relationships and school
performance
 Can cause low self-esteem, poor frustration tolerance, depressed mood, and
temper outbursts
 Adolescents may abuse alcohol and illegal substances
 May evolve into a conduct disorder or a mood disorder
Oppositional Defiant Disorder
 Poor prognosis: early onset, longer duration of symptoms, co-morbid
anxiety, impulse control & substance misuse
 Management:
 Family intervention using both direct training of the parents in child
management skills and careful assessment of family interactions
 With the child, use collaborative problem solving skills
 Teach parents how to alter their behavior to discourage the child's
oppositional behavior and encourage appropriate behavior
 Selective reinforcement and praising of appropriate behaviors
 Ignoring or not reinforcing undesired behavior
Conduct Disorder
Conduct Disorder
 Severe and persistent pattern of antisocial, aggressive or defiant behaviors
that defy age appropriate societal norms
 Four categories:
 Physical aggression or threats of harm to people, cruelty to people and
animals
 Destruction of their own property or that of others
 Theft or acts of deceit
 Frequent and serious violation of age appropriate rules (truancy/running
away)
 At least one behavior for at least six months
 Begins usually before the age of 13
 Prevalence of 5-7%
 More common among boys than girls (4:1)
Conduct Disorder
 Three most significant risk
factors (Ontario Child Health
Survey,1987):
 Family dysfunction
 Parental mental illness
 Low income
 Other risk factors (Rutter,1978):
 Criminality of father
 Overcrowding
 Maternal neurosis
 Institutional care
 Chronic marital discord
 Biological risk factors
 Temperament:
‘callous-unemotional’
 Brain injury
 Neuro-chemical: Low CSF
serotonin seen in more
aggressive behavior
 Low IQ
Conduct Disorder
 Psychosocial risk factors:
 Maternal smoking during pregnancy
 Parental criminality and substance abuse
 Harsh and inconsistent parenting
 Lack of a warm parental relationship and cold/rejecting family relationships
 Domestic violence in the family and child abuse
 Large family size
 School failure and poor school achievement
 Social isolation
Conduct Disorder
 Conduct disorders further predict risk for numerous problems in adulthood
that includes (Moffitt, 2002)
 Criminality and ASPD (antisocial personality disorder)
 Serious difficulties in education, work and finances
 Homelessness and abuse
 Drug and alcohol dependence
 Poor physical health including injuries, sexually transmitted infections,
compromised immune function
 Variety of mental disorders and suicidal behavior
Conduct Disorder
Conduct Disorder
 Treatment is multimodal
 Psychological therapies form the mainstay of treatment
 Parent Management Training based on the principles of social learning
theory has been very successful
 NICE recommends group based parent training/education programmes as
mainstay of treatment
 Cognitive behavioral therapy:
 Social skills training
 Anger management
 Common targets – aggression, social interaction, self evaluation and
emotional dysregulation
Conduct Disorder
 Functional family therapy: practicable and relatively inexpensive. There
are four phases of treatment which includes Engagement, Motivation,
Behavioral Change and Generalization (reduce reoffending rates by 50%)
 Multi-systemic therapy: Address specific individual difficulties and promote
strengths
 Other treatment options:
 Treat any co-morbidity
 Address any child protection concerns
 Anger Management Programme
To be continued…
References
 Kaplan and Sadock’s Synopsis of Psychiatry
 Rutter’s Textbook of Child Psychiatry
 SPMM Clinical Notes in Child Psychiatry
Child Psychiatry - Part 1

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Child Psychiatry - Part 1

  • 1. Child Psychiatry – Part 1 Dr Bhakti Murkey Assistant Professor, Department of Psychiatry (PMCH Udaipur)
  • 2. Outline  Classification (ICD-10)  History taking in Child Psychiatry  ADHD  Autism  Asperger’s Syndrome  Intellectual Disability Disorder  Specific Learning Disorders  Tic Disorder  Disruptive Behavior Disorders  Oppositional Defiant Disorder  Conduct Disorder  Anxiety Disorders in children  Childhood Depression  Childhood Mania  Childhood onset Schizophrenia  Elimination Disorders  Rating Scales in children  References
  • 3. Classification of Childhood Psychiatric Disorders (ICD-10)  F 70-73: Mental Retardation  F 80-83: Specific Developmental Disorders  F 84: Pervasive Developmental Disorder  F 90: Hyperkinetic Disorder  F 91: Conduct Disorder  F 93: Emotional Disorders with childhood onset  F 94: Disorders of social functioning  F 95:Tic Disorder
  • 4. History Taking in Child Psychiatry  Chief complaints  History of Present Illness  Past History  Personal History  Medication History  Family History  Social History  Childhood History
  • 5. Childhood History  Pregnancy  Perinatal history: birth asphyxia? LBW? NICU stay? Major medical/ surgical illness?  Developmental milestones: gross and fine motor, social and language  Behavioral symptoms: temper tantrums, head-banging, thumb-sucking, regressive behavior, stereotypy?  Schooling history: behavior, performance at school, any complaints? Relationship with peers?  Assessment of Temperament
  • 8. Childhood History contd…  Family environment  Parenting styles  Relationship with sibling/s  Any major life events or recent stressor (for example, death of pet or change in school, etc)  Feeding and sleep patterns  Indulgence in substance use
  • 9. Effect of Maternal Depression
  • 11. Attention Deficit Hyperactivity Disorder  Impairment in attention and/or hyperactivity-impulsivity  In at least 2 settings  Interfering with developmentally appropriate functioning (social, academic or extracurricular)  For at least 6 months  1-2% prevalence  3 times more common in boys  Genetic vulnerability  DA and NA dysfunction in prefrontal cortex  Up to 50% children will have other co-morbid psychiatric illnesses
  • 12. Attention Deficit Hyperactivity Disorder  Up to15% of cases continue to meet diagnostic criteria for ADHD at the age of 25 years  50% of individuals will suffer some impairment from residual symptoms  5 times greater risk for antisocial behavior, substance abuse and other psychiatric disorders  15-20% develop substance misuse problems  Poor prognosis if early stressful life experiences (poverty, overcrowding, expressed emotions and parental psychopathology) or severe symptoms, predominantly hyperactive - impulsive and associated with conduct, language or learning disorder
  • 16. Autism Spectrum Disorder (Pervasive Developmental Disorders)
  • 17. Autism Spectrum Disorder (Pervasive Developmental Disorders)  PDD is an umbrella term, which includes Autism, Asperger’s syndrome, Rett’s syndrome and Childhood Disintegrative Disorder  Characterized by: impaired reciprocal social interactions, communication difficulties, aberrant language development, and restricted behavioral repertoire  Typically emerge before the age of 3 years  Four times more frequent in boys  There is no cure or treatment for autism  Early and effective management is desirable for a better outcome, and involves a comprehensive assessment of the child and family’s needs
  • 18. Autism Spectrum Disorder (Pervasive Developmental Disorders)  Management aimed at helping the family, providing vocational training and support to the person  Psychotherapy may be helpful for verbal skills  Specific intervention programmes:  Applied Behavior Analysis program: based on operant conditioning, imitation and reinforcement  TEACCH – Treatment and Education for Autistic and related Communication Handicapped Children program: based on the belief that children are motivated to learn language, successful in reducing self injurious behaviors and enhancing life skills
  • 19. Autism Spectrum Disorder (Pervasive Developmental Disorders)  Pharmacotherapy commonly used as adjunct  SSRIs - most widely used for restricted repetitive behaviors  Second generation antipsychotics are the first line treatment for associated irritability and aggression  The only licensed medication is Risperidone (0.5 – 2 mg/day)
  • 20. Asperger’s Syndrome  Same type of qualitative abnormalities in reciprocal social interaction that typify autism with a restricted, stereotyped and repetitive, repertoire of behavior/interests  IQ and language are usually within normal limits  No significant delays occur in relation to language development., cognitive development, and/or age appropriate self help skills  One third as common as autism with a prevalence of about 6 in 10,000  Normal IQ and high level social skills have good prognosis
  • 21. Rett’s Syndrome  Rare X linked dominant disorder  Almost exclusively affects females  Head circumference normal at birth and developmental milestones unremarkable in early life  Between 6-18 months, head growth begins to decelerate and produces microcephaly  Loss of purposeful hand movements  Stereotypic hand wringing  Loss of previously acquired speech  Psychomotor retardation and ataxia  Both receptive and expressive communicative and social skills plateau  Poor muscle coordination  Unsteady gait  Associated seizures in up to 75% cases  Irregular respiration, with episodes of hyperventilation, apnoea and breath holding
  • 22. Childhood Disintegrative Disorder  Heller’s disease  Marked regression in several areas of functioning after at least 2 years of apparently normal development  Loss of acquired motor, language, and social skills between ages 3 and 4 years  Loss of skills in two of the following areas: language, social or adaptive behavior; bowel or bladder control, play and motor skills  Abnormality in at least two of the following categories: reciprocal social interaction, communication skills, and stereotyped or restricted behavior  Associated seizure disorder  Male predominance  Poor prognosis
  • 24. Mental Retardation (Intellectual Disability Disorder)  Developmental disability marked by lower-than-normal intelligence and limited daily living skills  Either normally present at birth or develops early in life  Types:  Borderline intelligence IQ < 80  Mild (IQ = 50-70)  Moderate (IQ = 35-50)  Severe (IQ = 20-35)  Profound (IQ < 20)
  • 25. Mental Retardation (Intellectual Disability Disorder)  Mild MR:  Individuals can often live on their own with community support  They have minimum retardation in sensory-motor areas  Moderate MR:  They are challenged academically and often are not able to achieve academically above a second to third grade level  As adults, they may be able to perform semiskilled work under appropriate supervision
  • 26. Mental Retardation (Intellectual Disability Disorder)  Severe MR:  Individuals can often master the most basic skills of living, such as cleaning and dressing themselves  Is often recognized early in life with poor motor development & absent or markedly delayed speech & communication skills  Profound MR:  Individuals can often develop basic communication and self-care skills  Most individuals have identifiable causes for their condition
  • 27. Mental Retardation (Intellectual Disability Disorder)  Causes:  Infections (present at birth or occurring after birth)  Chromosomal abnormalities:  Chromosome deletions  Defects in chromosomal inheritance  Errors of chromosome numbers  Problems at birth:  Difficult labor or perinatal hypoxia  Problems during pregnancy (TORCH infection)  Exposure to certain toxins/ teratogenic medication
  • 28. SpLD (Specific Learning Disability)  Problems with educational achievements  Performance significantly below that expected for IQ or age  Under-achievement in reading, written expression, or mathematics  Genetic predisposition, peri-natal injury and neurological and other medical conditions can contribute  Affect at least 5% of school age children  Associated with up to 50% risk of co-morbid disorders, including ADHD, communication disorders, conduct disorders and depression  Commonly present as emotional or behavioral problems  Strong evidence of heritability
  • 30. Tic Disorder (Tourette Syndrome)  Multiple motor and/ or vocal tics  Present for at least a year  Significant distress and impaired function  Facial tics: eye blinks or head jerks are often the initial symptoms, but tics involving the neck, shoulders, and upper extremities are also common  Vocal tics begin 1- 2 yrs after the onset of motor symptoms and range from meaningless sounds to clear words  Vocal tics are crucial for diagnosis and may be barks, hisses, hoots and not necessarily obscene blasphemous utterances (coprolalia), echolalia, or palilalia(repeating ones own speech)  Treatment: low dose Anti-psychotics (Haloperidol/ Risperidone)
  • 32. Oppositional Defiant Disorder  Enduring pattern of negative, hostile, disobedient and defiant behavior, without serious violations of societal norms or the rights of others  For at least 6 months  Temper outbursts, active refusal to comply with rules, tendency to blame others, spiteful and annoying behaviors  Can begin as early as 3 years of age, typically noted by 8 years  Prevalence 2-5%  More prevalent in boys than in girls  25% cases show no symptoms in later life but many progress to conduct disorder
  • 33. Oppositional Defiant Disorder  Aetiology: temperamental factors like sick or traumatized child and power struggle between parents & child  ADHD in early life is a predictor of oppositional defiant disorder and conduct disorder later in life  Almost always interferes with interpersonal relationships and school performance  Can cause low self-esteem, poor frustration tolerance, depressed mood, and temper outbursts  Adolescents may abuse alcohol and illegal substances  May evolve into a conduct disorder or a mood disorder
  • 34. Oppositional Defiant Disorder  Poor prognosis: early onset, longer duration of symptoms, co-morbid anxiety, impulse control & substance misuse  Management:  Family intervention using both direct training of the parents in child management skills and careful assessment of family interactions  With the child, use collaborative problem solving skills  Teach parents how to alter their behavior to discourage the child's oppositional behavior and encourage appropriate behavior  Selective reinforcement and praising of appropriate behaviors  Ignoring or not reinforcing undesired behavior
  • 36. Conduct Disorder  Severe and persistent pattern of antisocial, aggressive or defiant behaviors that defy age appropriate societal norms  Four categories:  Physical aggression or threats of harm to people, cruelty to people and animals  Destruction of their own property or that of others  Theft or acts of deceit  Frequent and serious violation of age appropriate rules (truancy/running away)  At least one behavior for at least six months  Begins usually before the age of 13  Prevalence of 5-7%  More common among boys than girls (4:1)
  • 37. Conduct Disorder  Three most significant risk factors (Ontario Child Health Survey,1987):  Family dysfunction  Parental mental illness  Low income  Other risk factors (Rutter,1978):  Criminality of father  Overcrowding  Maternal neurosis  Institutional care  Chronic marital discord  Biological risk factors  Temperament: ‘callous-unemotional’  Brain injury  Neuro-chemical: Low CSF serotonin seen in more aggressive behavior  Low IQ
  • 38. Conduct Disorder  Psychosocial risk factors:  Maternal smoking during pregnancy  Parental criminality and substance abuse  Harsh and inconsistent parenting  Lack of a warm parental relationship and cold/rejecting family relationships  Domestic violence in the family and child abuse  Large family size  School failure and poor school achievement  Social isolation
  • 39. Conduct Disorder  Conduct disorders further predict risk for numerous problems in adulthood that includes (Moffitt, 2002)  Criminality and ASPD (antisocial personality disorder)  Serious difficulties in education, work and finances  Homelessness and abuse  Drug and alcohol dependence  Poor physical health including injuries, sexually transmitted infections, compromised immune function  Variety of mental disorders and suicidal behavior
  • 41. Conduct Disorder  Treatment is multimodal  Psychological therapies form the mainstay of treatment  Parent Management Training based on the principles of social learning theory has been very successful  NICE recommends group based parent training/education programmes as mainstay of treatment  Cognitive behavioral therapy:  Social skills training  Anger management  Common targets – aggression, social interaction, self evaluation and emotional dysregulation
  • 42. Conduct Disorder  Functional family therapy: practicable and relatively inexpensive. There are four phases of treatment which includes Engagement, Motivation, Behavioral Change and Generalization (reduce reoffending rates by 50%)  Multi-systemic therapy: Address specific individual difficulties and promote strengths  Other treatment options:  Treat any co-morbidity  Address any child protection concerns  Anger Management Programme
  • 44. References  Kaplan and Sadock’s Synopsis of Psychiatry  Rutter’s Textbook of Child Psychiatry  SPMM Clinical Notes in Child Psychiatry