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
 DR.KHURSHID ALAM
 MEDICAL OFFICER
 VAISHALI
 Acute encephalitis syndrome
 Long standing mystery disease
 Affecting mainly north bihar
especially MUZAFFARPUR
 Mystery since two decades
 First noticed in2008
 Claimed over more than thousand death
 Occurs in summer
 Has direct correlation with heat and humidity
 Arrival of monsoon leads to end of this
disease
 Unknown etiology
 Clinically neurological manifestation caused
by wide range of bacteria, virus, chemical,
fungus etc
SYMPTOM
 High fever with change in mental status
including symptoms such as confusion ,
disorientation , inability to talk , seizure ,
coma
AFFECTED AGE GROUP
1-10 years
RESEARCH
 DR.T Jacob ( it is caused by a toxic substance
in lichi
 AIIMS-Patna (it is due to contaminated water
in Gandak river
 RMRI MS- (Published a hypothesis in
international journal of current microbiology
and applied science in Nov.13
LAB INVESTIGATION
 Nothing detected in Blood , Brain , other
Body fluid and Body organ
 Low blood sugar in most of the patient
 Majority of patient are malnourished and
belonged to low socio economic group
MANAGEMENT
 Mainly symptomatic
 Paracetamol for fever
 Seadetive for convulsion
 DNS/10% Dextrose for hopoglysemia
 Oxygen
 Ventilatory support
PREVENTION
JEVaccination
Prevent mosquito bite
Prevent sun stroke
Don’t eat contaminated fruit and water
Stay away from pig
Don’t miss dinner
 A mystery ………………
SOLVE IT !!!!!!
THANKYOU

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AES Muzaffarpur.pptx

  • 1.
  • 2.   DR.KHURSHID ALAM  MEDICAL OFFICER  VAISHALI
  • 3.  Acute encephalitis syndrome  Long standing mystery disease  Affecting mainly north bihar especially MUZAFFARPUR
  • 4.  Mystery since two decades  First noticed in2008  Claimed over more than thousand death  Occurs in summer  Has direct correlation with heat and humidity  Arrival of monsoon leads to end of this disease
  • 5.  Unknown etiology  Clinically neurological manifestation caused by wide range of bacteria, virus, chemical, fungus etc
  • 6. SYMPTOM  High fever with change in mental status including symptoms such as confusion , disorientation , inability to talk , seizure , coma AFFECTED AGE GROUP 1-10 years
  • 7. RESEARCH  DR.T Jacob ( it is caused by a toxic substance in lichi  AIIMS-Patna (it is due to contaminated water in Gandak river  RMRI MS- (Published a hypothesis in international journal of current microbiology and applied science in Nov.13
  • 8. LAB INVESTIGATION  Nothing detected in Blood , Brain , other Body fluid and Body organ  Low blood sugar in most of the patient  Majority of patient are malnourished and belonged to low socio economic group
  • 9. MANAGEMENT  Mainly symptomatic  Paracetamol for fever  Seadetive for convulsion  DNS/10% Dextrose for hopoglysemia  Oxygen  Ventilatory support
  • 10. PREVENTION JEVaccination Prevent mosquito bite Prevent sun stroke Don’t eat contaminated fruit and water Stay away from pig Don’t miss dinner
  • 11.  A mystery ……………… SOLVE IT !!!!!! THANKYOU