Development of Genital System

1. DEVELOPMENT OFDEVELOPMENT OF
GENITAL SYSTEMGENITAL SYSTEM
Development of GonadsDevelopment of Gonads
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2. Anatomy of Male
Genital System
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4. Seminiferous tubules
Rete testis
Head of epididymis
Body of epididymis
Tail of epididymis
Vas deference
Tunica
albuginea
Tunica
vaginalis
Testis
Vasa efferentia
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5. Ureter
Vas
defference
Seminal vesicle
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6. Anatomy of Female
Genital system
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9. Development of
Gonads
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10. A- Indifferent Gonads
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16. Comparison betweenComparison between
development of testisdevelopment of testis
& ovary& ovary
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18. DEVELOPMENT OFDEVELOPMENT OF
TESTISTESTIS
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19. From the 7th
week
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22. Descend of TestisDescend of Testis
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28. Congenital AnomaliesCongenital Anomalies
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29. A- Abnormal formation:
1- Gonadal dysgenesis.
2- Klinefelter syndrom (47, XXY)
3- Hermaphrodites (intersex): True or
pseudo.
B- Abnormal Descent:
1- Undescended testis (Cryptorchism)
2- Ectopic testis
C- Anomalies of processus vaginalis:
1- Congenital hydrocele.
2- Congenital inguinal hernia.
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32. DEVELOPMENT OFDEVELOPMENT OF
OVARYOVARY
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37. Descend of OvaryDescend of Ovary
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40. DEVELOPMENT OFDEVELOPMENT OF
GENITAL DUCTSGENITAL DUCTS
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MESONEPHRIC &MESONEPHRIC &
PARAMESONEPHRIC DUCTPARAMESONEPHRIC DUCT
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41. Anatomy of Female
Genital system
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44. Paramesonephric
duct (evagination of
celomic epithelium)
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55. PARAMESONEPHRIC DUCTPARAMESONEPHRIC DUCT
 Two ducts which are formed by evagination ofTwo ducts which are formed by evagination of
coelomic epithelium.coelomic epithelium.
 Cranial end of the duct communicates withCranial end of the duct communicates with
coelomic cavity.coelomic cavity.
 It has 3 parts:It has 3 parts:

Cranial vertical partCranial vertical part which lies lateral towhich lies lateral to
mesonephric duct.mesonephric duct.

Middle horizontal partMiddle horizontal part which is ventral towhich is ventral to
mesonephric duct.mesonephric duct.

Caudal vertical partCaudal vertical part which is medial to mesonephricwhich is medial to mesonephric
duct. They are blind caudal ends which lie induct. They are blind caudal ends which lie in
contact with the back of defenitive uro-genital sinus.contact with the back of defenitive uro-genital sinus.
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56. Congenital AnomaliesCongenital Anomalies
A- Failure of fusion between 2 para-
mesonephric ducts:
- Double uterus and vagina.
- Double uterus and single vagina.
- Double uterus, single cervix and single
vagina.
- Septate uterus.
- Arcuate uterus. Dr.Sherif Fahmy

57. B- Incomplete development of one
uterine tube:
-Unicornuate uterus with rudimentary horn.
C- Failure or incomplete canalization of
paramesonephric ducts:
- Atresia of cervix.
-Atresia of vagina.
-Imperforate hymen.
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59. DEVELOPMENT OF EXTERNALDEVELOPMENT OF EXTERNAL
GENITAL ORGANGENITAL ORGAN
A-A- Indifferent stage:Indifferent stage:
 It starts at the 3It starts at the 3rdrd
week by the appearance of cloacalweek by the appearance of cloacal
folds on both sides of cloacal membrane.folds on both sides of cloacal membrane.
 With division of cloacal membrane, cloacal folds divideWith division of cloacal membrane, cloacal folds divide
into genital and anal folds.into genital and anal folds.
B-B- Differentiation:Differentiation:
 At the end of 3At the end of 3rdrd
month, genital folds unites anteriorlymonth, genital folds unites anteriorly
to form genital tubercle that form phalus in male andto form genital tubercle that form phalus in male and
clitoris in female. The genital folds become uretheralclitoris in female. The genital folds become uretheral
fold in male and labia minora in female.fold in male and labia minora in female.
 Genital swellings appear on both sides of genital foldsGenital swellings appear on both sides of genital folds
that unite together in male forming scrotum andthat unite together in male forming scrotum and
remain separate in female forming labia majora.remain separate in female forming labia majora.
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63. CONGENITAL ANOMALIESCONGENITAL ANOMALIES
 1-1- Hypospadius:Hypospadius: Opening of urethera on lowerOpening of urethera on lower
surface of penis due to failure of fusion of uretheralsurface of penis due to failure of fusion of uretheral
folds.folds.
 2-2- Clitoris hypertrophy:Clitoris hypertrophy: overgrowth of genitalovergrowth of genital
tubercle.tubercle.
 3-3- Undersized penis:Undersized penis: undergrowth of genital tubercle.undergrowth of genital tubercle.
 4-4- Bifid scrotum:Bifid scrotum: failure of fusion of genital swellings.failure of fusion of genital swellings.
 5-5- Pseudohermaphrodite:Pseudohermaphrodite: External genitalia belongExternal genitalia belong
to one sex and the gonads belong to the other.to one sex and the gonads belong to the other.
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