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Left Atrial Myxoma
A Review For Medical Students
Dr B Vivek Baliga
Consultant Physician And Director
Baliga Diagnostics
WHAT YOU WILL LEARN
1. What is LA Myxoma?
2. Pathology
3. Clinical Features
4. Diagnostic methods
5. Management
6. MCQs
2
INTRODUCTION
Cardiac tumours are a commonly asked question in medical
exams.
The most common cardiac tumour that is encountered in
clinical practice is a left atrial myxoma.
3
POSSIBLE QUESTIONS
1. Write a note on Left atrial myxoma
2. Discuss cardiac tumors
3. Write a note on the most common cardiac tumor
LA MYXOMA
▹ Most common type of primary
cardiac tumor that is seen in
adults.
▹ Predominantly seen in females
▹ Between the ages of 30 and 60
years
4
CLASSIFICATION
5
2 BASIC TYPES6
SPORADIC
90% of cases
Usually solitary
FAMILIAL
10% of cases
Tend to be
multiple
PART OF CLINICAL SYNDROMES
Carney Complex
LAMB Syndrome
NAME syndrome
PATHOLOGY
▹ Primarily composed of a gelatin -like structure that contains
myxoma cells in a stroma composed of glycosaminoglycans.
▹ Myxomas produce vascular endothelial growth factor which is
responsible for its enlargement of size.
▹ Typical myxomas range between 1 to 15 cm in diameter.
▹ Around 30% of these tumours have a friable surface and can
embolize.
7
Imagecourtesy Wikimediacommons,user Nephron
SITE AND LOCATION
Myxomas are mostly present in the left
atrium, and are attached through a
pedicle to the fossa ovalis.
The pedicle consists of fibrous and
vascular tissue.
8
CLINICAL FEATURES
9
SYMPTOMS
▹ Early stages - No symptoms
▹ Later - Features of cardiac
failure
▹ ‘Tumor plop’ - Heard in early
diastole
▹ May be associated MR
▹ Constitutional symptoms -
fever, malaise etc
10
COMPLICATIONS
1. Mitral valve - mitral stenosis or
mitral regurgitation
2. Embolism - peripheral or
neurological
11
DIAGNOSIS
12
ECHOCARDIOGRAPHY IS CONFIRMATORY
13
14 MANAGEMENT
▹ Surgical excision through cardiopulmonary
bypass.
▹ Surgical mortality risk is less than 5%.
▹ This treatment is curative and only 1 to 2% of
sporadic cases recur.
▹ Familial cases have a slightly higher recurrence
rate of up to 20%.
15
For more information and exam
questions on LA myxoma, visit the link
in the description.

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LA Myxoma - For Medical Students

  • 1. Left Atrial Myxoma A Review For Medical Students Dr B Vivek Baliga Consultant Physician And Director Baliga Diagnostics
  • 2. WHAT YOU WILL LEARN 1. What is LA Myxoma? 2. Pathology 3. Clinical Features 4. Diagnostic methods 5. Management 6. MCQs 2
  • 3. INTRODUCTION Cardiac tumours are a commonly asked question in medical exams. The most common cardiac tumour that is encountered in clinical practice is a left atrial myxoma. 3 POSSIBLE QUESTIONS 1. Write a note on Left atrial myxoma 2. Discuss cardiac tumors 3. Write a note on the most common cardiac tumor
  • 4. LA MYXOMA ▹ Most common type of primary cardiac tumor that is seen in adults. ▹ Predominantly seen in females ▹ Between the ages of 30 and 60 years 4
  • 6. 2 BASIC TYPES6 SPORADIC 90% of cases Usually solitary FAMILIAL 10% of cases Tend to be multiple PART OF CLINICAL SYNDROMES Carney Complex LAMB Syndrome NAME syndrome
  • 7. PATHOLOGY ▹ Primarily composed of a gelatin -like structure that contains myxoma cells in a stroma composed of glycosaminoglycans. ▹ Myxomas produce vascular endothelial growth factor which is responsible for its enlargement of size. ▹ Typical myxomas range between 1 to 15 cm in diameter. ▹ Around 30% of these tumours have a friable surface and can embolize. 7 Imagecourtesy Wikimediacommons,user Nephron
  • 8. SITE AND LOCATION Myxomas are mostly present in the left atrium, and are attached through a pedicle to the fossa ovalis. The pedicle consists of fibrous and vascular tissue. 8
  • 10. SYMPTOMS ▹ Early stages - No symptoms ▹ Later - Features of cardiac failure ▹ ‘Tumor plop’ - Heard in early diastole ▹ May be associated MR ▹ Constitutional symptoms - fever, malaise etc 10
  • 11. COMPLICATIONS 1. Mitral valve - mitral stenosis or mitral regurgitation 2. Embolism - peripheral or neurological 11
  • 14. 14 MANAGEMENT ▹ Surgical excision through cardiopulmonary bypass. ▹ Surgical mortality risk is less than 5%. ▹ This treatment is curative and only 1 to 2% of sporadic cases recur. ▹ Familial cases have a slightly higher recurrence rate of up to 20%.
  • 15. 15 For more information and exam questions on LA myxoma, visit the link in the description.