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OSCE
4 March-08
 th




Center For Child Health
Sir Ganga Ram Hospital
Spot 1
                                  10 yr old male
                                  child presented
                                  with multiple
                                  cranial nerve
                                  palsies of 2 wks
                                  duration. MRI
                                  done is shown
                                  here



  • Spot the diagnosis with type
  • Views of picture A and B and what does
    the MRI depicts
  • Early important clinical clue for
    hydrocephalus after 1st month of life
•   Severe communicating hydrocephalus
•   Contrast-enhanced axial (A) and coronal
    (B) T1- weighted MR images depict
    diffuse leptomeningeal enhancement in
    the basal cistern. Strong enhancement
    of the bilateral thickened third nerves
    (arrowheads in A)
•   Open squamo parietal suture beyond
    first month of life
Spot 2
                          Prematurely (28 wks)
                          born SGA baby,
                          ventilated for 18 days,
                          hemodynamically was
                          unstable and had
                          neonatal seizures. USG
                          cranium done at 6 wks of
                          age is shown here…

  • Name the investigation with view
  • Spot the diagnosis with grade
  • Significance of the diagnosis and
    intervention
  • Protective antenatal factors
• Sonogram cranium (coronal view)
  showing cystic periventricular
  leukomalacia
• Cystic Periventricular Leukomalacia,
  Grade III (De Veries classification)
• C-PVL strongest indicator of cerebral
  palsy, especially spastic diplegia so
  palsy
  early stimulation programme with
  occupational therapy
• Antenatal steroids and Anemia
Spot 3
                              3 yr old male child from Utter
                              Pradesh admitted with high
                              grade fever x 4-5 days and
                              generalized seizures for 1 day.
                              There were (B/L)6th and 7th CN
                              palsy with dystonias. Similar
                              cases are being reported from
                              the same area. His most
                              important investigation is given
                              here….

 Name of the investigation and identify the Spot
 Main transmitter to man
 Subclinical cases, what %
 Preventive strategy
• T2-weighted MRI of the brain
  showing Panda sign
• Female Culex mosquito (Culex
  tritanirhynchus and Vishnui)
                       Vishnui
• 99% cases are sub clinical
• Vaccine in the inter epidemic
  period and Fogging with
  malathion sprayed in 3 km range
  from the infected cases
Spot 4

                                   EEG of a 60 hrs old
                                   newborn who required
                                   resuscitation at Birth
                                   with a 5 minute APGAR
                                   of 5. Child had seizures
                                   in first 12 hrs of life


 Identify the spot
 Its significance
 Name of the staging system other than Sarnat and Sarnat
 and give its component
• EEG showing Burst Suppression
 pattern
• It indicates serious outcome in HIE
 patients
• Levene’s staging system (Mild,
 Moderate and Severe)
  – Consciousness
  – Tone
  – Seizures
  – Sucking/Respiration
Spot 5
                            11 yrs old male child
                            admitted with slurring of
                            speech, ataxia and
                            dystonias. On inv.he found
                            to have renal tubular
                            acidosis and active rickets.



 Give the most possible diagnosis
 Pattern of inheritance
 Most specific investigation
 Specific treatment and advise to family
 members
• Wilson disease with lenticular
 degeneration
• Autosomal recessive

• Hepatic copper content (µg/gm dry wt. of
 liver- it exceeds >250 µg/gm dry wt.)
• D-Penicillamine with Pyridoxine and Zinc
 and all family members should be screen
 with slit lamp examination
Spot 6                     4 yrs old male child
                           brought with a history of
                           developmental delay. He
                           found to have mild
                           mental retardation and
                           Sensory neuropathy. He
                           is from low SE group
                           and his father is a
                           laborer. X-ray is shown
                           here…..


         Most probable diagnosis
         Treatment options
         Indication for treatment
         Urine investigation
• Lead posioning

• CaNa2EDTA (Calcium Versanate) and BAL

 in symptomatic child

• If lead levels >45 µgm% (N <10 µgm%)

• Urine – Increased Zinc protoporphyrin
Spot 7                           6 yrs old male child
                                 presented with seizures,
                                 delayed development, some
                                 problem in vision and
                                 fainting attack which are
                                 not due to seizures. He had
                                 myoclonic seizures during
                                 the infancy. His only clinical
                                 finding is given here

 Possible diagnosis and spot the arrowed structure
 Pattern of inheritance
 Investigation you would ask for and what do you expect
 One eye finding
 Treatment of choice for seizures and its important ocular
 S?E
• Tuberous Sclerosis, Ash leaf
           Sclerosis
  macule
• Autosomal Dominant trait
• CT head for subependymal nodes
• Retinal hamartoma
• Vigabatrin and loss of peripheral
 vision
Spot 8




  • Identify the Spot
  • Main Uses
  • Normal test indicates what?
• BERA- Brainstem Evoked
  BERA
 Response Audiometry
• Post meningitis/Bilirubin induced
 neurotoxity
• Normal test – normal retro
 cochlear nervous pathway
Spot 9

Six days after undergoing liver
transplantation, a 12 yr old patient's levels
of gamma-glutamyl transferase (GGT),
alkaline phosphatase, and bilirubin begin
to rise.
   •Which is the most appropriate next step
   in diagnosis?
   •What if kidneys were transplanted and
   BUN/Cr used to be increased and why?
• Ultrasound of biliary tract and Doppler studies of the
  anastomosed vessels
• In all other solid organ transplants, deterioration of
  function 5-6 days out would suggest an acute
  rejection episode, and appropriate biopsies would
  be done to confirm the diagnosis.


  In the case of the liver, however, antigenic reactions
                     liver
  are less common, whereas technical problems with
  the biliary and vascular anastomosis are the most
  common cause of early functional deterioration.
Spot 10

A 3-year old boy presented with FTT. The
child was apparently fine for the first
couple of years. He began to have
diarrhea with light colored stools. Although
stool examinations were performed, it was
unclear what the report is. The child was
placed on a high protein, high calorie diet
with vitamins and supplements. However,
he showed very little improvement over a
                                               •Identify the spot
4 month period. Barium exam showed
"large dilated loops of hypotonic bowel"),     •Best diagnostic
the child was admitted with a diagnosis of     possibility
celiac disease. Stool examinations has
                                               •Treatment ?
shown in the picture
• This image contains a Giardia lamblia
 trophozoite
• Three stool examinations on altrenate
 days detects around 90%
• Metronidazole is the treatment of
 Choice x 5 days and Others are
 Albendazole, Furazolidine
Spot 11

• A 13-year-old, obese boy complains of persistent knee pain
  for several weeks. The family brings him in because he has
  been limping. He sits in the examining table with the sole of
       limping
  the foot on the affected side pointing to the other leg.
  Physical examination is normal for the knee, but shows
  limited hip motion. As the hip is flexed, the leg goes into
              motion
  external rotation and cannot be rotated internally.
                                          internally



   Which of the following is the
   most likely diagnosis?
• Slipped capital femoral epiphysis is an

 orthopedic emergency.

  – The clinical picture is classic: a chubby male

    in his early teens who is limping and cannot

    rotate his leg internally.
Spot 12

• A 14-year-old boy dives into the shallow end of a
  swimming pool and hits his head against the
  bottom. When he is rescued, he shows a complete
  lack of neurologic function below the neck. He is
                                        neck
  still breathing on his own, but he cannot move or
                         own
  feel his arms and legs. The paramedics carefully
                      legs
  immobilize his neck for transportation to the
  hospital, and they alert the emergency department
  to his impending arrival.
   – Once there, which treatment would most likely have an
     immediate benefit for this patient? (other than ABC)
• There is some evidence that high-

 dose corticosteroids administered as

 soon as possible after the injury will

 result in a better ultimate outcome
Spot 13




  • 8 yrs old child resident of Delhi is admitted with
    fever x 5-6 days, loss of appetite x 6 days and
    hepato splenomegaly. His peripheral smear is
    shown above
     – Spot the picture (name the form of parasite)
     – Name of the culture media
     – Drugs used to treat resistant cases
• Kala Azar (LD bodies-Amastigote form,
                                  form
 non flagelated form)

• NNN media (Novy, MacNeil & Nicolle)

• AMB, Pentamidine, Aminosidine,

 Miltefosine, Recombinant INF gamma,

 Allopurinol and adjunct splenectomy
Spot 14

  2 month old male, "fussy", diarrhea and vomiting;
  flatulence. Breast-fed. He had Viral gastroenteritis
  10 days previously. Before the infection, mother's
  milk was well tolerated. Body weight within normal
  limits. Moderately dehydrated. Urine shows
  presence of reducing sugars. No reaction for
  glucose. You make a diagnosis of lactose
  intolerance and start him on reduced lactose diet..


  • Indications for changing diet in case
    of non or poor response
  • What are diet A, B and C
• Indications
  – Stool frequency >10 watery stool/day even
    after 48 hrs of starting diet
  – Return of the signs of dehydration any time
    after staring diet
  – Failure to establish wt,gain by 7th day of
    dietary management
• Types of diet
  – Diet A (reduced lactose)
  – Diet B (lactose free)
  – Diet C (Monosaccharide diet)
Spot 15
 2 yr old male child presented with diarrhea of 3 wks
   duration with failure to thrive. He was started with
   nutrition rich feeds (Simyl-MCT drops, HMF
   sachet and pedia sure) and antibiotics at a
                        sure
   peripheral health center 7 fays back. Since then
   diarrhoea has even increased and patient is
   loosing weight. He was Moderately dehydrated at
   admission. His daily stool output comes around
   185 ml and his stool Na+ 42 mEq/L and K+ 3.8
   mEq/L. Sister didn’t sent the stool pH and
   mEq/L
   reducing substance.

  What is the diagnosis based on these investigations
  Calculate the osmotic Gap
  What is the treatment next
• Chronic diarrhoea (Secondary
  lactose intolerance- Osmotic
  diarrhoea)
  diarrhoea
• Osmotic Gap : 290-(2 x Stool Na+K)
  If Gap >100 its osmotic diarrhoea
• Remove the osmotic load from the
  diet and stop feeding for 24 hrs and
  then restart the lactose free diet
  without adding any nutritional stuff
http://groups.yahoo.com/group/PediatricsDNB/


         Theory: http://dnbpediatricstheory.blogspot.in/

         OSCE: http://oscepediatrics.blogspot.in/

         Clinical: http://clinicalpediatrics.blogspot.in/

        Practicals: http://practicalpediatrics.blogspot.in/


Download at: http://www.4shared.com/folder/t8E_yjDv/_online.html

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OSCE IN PEDIATRICS (March 4th 2008) SGRH

  • 1. OSCE 4 March-08 th Center For Child Health Sir Ganga Ram Hospital
  • 2. Spot 1 10 yr old male child presented with multiple cranial nerve palsies of 2 wks duration. MRI done is shown here • Spot the diagnosis with type • Views of picture A and B and what does the MRI depicts • Early important clinical clue for hydrocephalus after 1st month of life
  • 3. Severe communicating hydrocephalus • Contrast-enhanced axial (A) and coronal (B) T1- weighted MR images depict diffuse leptomeningeal enhancement in the basal cistern. Strong enhancement of the bilateral thickened third nerves (arrowheads in A) • Open squamo parietal suture beyond first month of life
  • 4. Spot 2 Prematurely (28 wks) born SGA baby, ventilated for 18 days, hemodynamically was unstable and had neonatal seizures. USG cranium done at 6 wks of age is shown here… • Name the investigation with view • Spot the diagnosis with grade • Significance of the diagnosis and intervention • Protective antenatal factors
  • 5. • Sonogram cranium (coronal view) showing cystic periventricular leukomalacia • Cystic Periventricular Leukomalacia, Grade III (De Veries classification) • C-PVL strongest indicator of cerebral palsy, especially spastic diplegia so palsy early stimulation programme with occupational therapy • Antenatal steroids and Anemia
  • 6. Spot 3 3 yr old male child from Utter Pradesh admitted with high grade fever x 4-5 days and generalized seizures for 1 day. There were (B/L)6th and 7th CN palsy with dystonias. Similar cases are being reported from the same area. His most important investigation is given here…. Name of the investigation and identify the Spot Main transmitter to man Subclinical cases, what % Preventive strategy
  • 7. • T2-weighted MRI of the brain showing Panda sign • Female Culex mosquito (Culex tritanirhynchus and Vishnui) Vishnui • 99% cases are sub clinical • Vaccine in the inter epidemic period and Fogging with malathion sprayed in 3 km range from the infected cases
  • 8. Spot 4 EEG of a 60 hrs old newborn who required resuscitation at Birth with a 5 minute APGAR of 5. Child had seizures in first 12 hrs of life Identify the spot Its significance Name of the staging system other than Sarnat and Sarnat and give its component
  • 9. • EEG showing Burst Suppression pattern • It indicates serious outcome in HIE patients • Levene’s staging system (Mild, Moderate and Severe) – Consciousness – Tone – Seizures – Sucking/Respiration
  • 10. Spot 5 11 yrs old male child admitted with slurring of speech, ataxia and dystonias. On inv.he found to have renal tubular acidosis and active rickets. Give the most possible diagnosis Pattern of inheritance Most specific investigation Specific treatment and advise to family members
  • 11. • Wilson disease with lenticular degeneration • Autosomal recessive • Hepatic copper content (µg/gm dry wt. of liver- it exceeds >250 µg/gm dry wt.) • D-Penicillamine with Pyridoxine and Zinc and all family members should be screen with slit lamp examination
  • 12. Spot 6 4 yrs old male child brought with a history of developmental delay. He found to have mild mental retardation and Sensory neuropathy. He is from low SE group and his father is a laborer. X-ray is shown here….. Most probable diagnosis Treatment options Indication for treatment Urine investigation
  • 13. • Lead posioning • CaNa2EDTA (Calcium Versanate) and BAL in symptomatic child • If lead levels >45 µgm% (N <10 µgm%) • Urine – Increased Zinc protoporphyrin
  • 14. Spot 7 6 yrs old male child presented with seizures, delayed development, some problem in vision and fainting attack which are not due to seizures. He had myoclonic seizures during the infancy. His only clinical finding is given here Possible diagnosis and spot the arrowed structure Pattern of inheritance Investigation you would ask for and what do you expect One eye finding Treatment of choice for seizures and its important ocular S?E
  • 15. • Tuberous Sclerosis, Ash leaf Sclerosis macule • Autosomal Dominant trait • CT head for subependymal nodes • Retinal hamartoma • Vigabatrin and loss of peripheral vision
  • 16. Spot 8 • Identify the Spot • Main Uses • Normal test indicates what?
  • 17. • BERA- Brainstem Evoked BERA Response Audiometry • Post meningitis/Bilirubin induced neurotoxity • Normal test – normal retro cochlear nervous pathway
  • 18. Spot 9 Six days after undergoing liver transplantation, a 12 yr old patient's levels of gamma-glutamyl transferase (GGT), alkaline phosphatase, and bilirubin begin to rise. •Which is the most appropriate next step in diagnosis? •What if kidneys were transplanted and BUN/Cr used to be increased and why?
  • 19. • Ultrasound of biliary tract and Doppler studies of the anastomosed vessels • In all other solid organ transplants, deterioration of function 5-6 days out would suggest an acute rejection episode, and appropriate biopsies would be done to confirm the diagnosis. In the case of the liver, however, antigenic reactions liver are less common, whereas technical problems with the biliary and vascular anastomosis are the most common cause of early functional deterioration.
  • 20. Spot 10 A 3-year old boy presented with FTT. The child was apparently fine for the first couple of years. He began to have diarrhea with light colored stools. Although stool examinations were performed, it was unclear what the report is. The child was placed on a high protein, high calorie diet with vitamins and supplements. However, he showed very little improvement over a •Identify the spot 4 month period. Barium exam showed "large dilated loops of hypotonic bowel"), •Best diagnostic the child was admitted with a diagnosis of possibility celiac disease. Stool examinations has •Treatment ? shown in the picture
  • 21. • This image contains a Giardia lamblia trophozoite • Three stool examinations on altrenate days detects around 90% • Metronidazole is the treatment of Choice x 5 days and Others are Albendazole, Furazolidine
  • 22. Spot 11 • A 13-year-old, obese boy complains of persistent knee pain for several weeks. The family brings him in because he has been limping. He sits in the examining table with the sole of limping the foot on the affected side pointing to the other leg. Physical examination is normal for the knee, but shows limited hip motion. As the hip is flexed, the leg goes into motion external rotation and cannot be rotated internally. internally Which of the following is the most likely diagnosis?
  • 23. • Slipped capital femoral epiphysis is an orthopedic emergency. – The clinical picture is classic: a chubby male in his early teens who is limping and cannot rotate his leg internally.
  • 24. Spot 12 • A 14-year-old boy dives into the shallow end of a swimming pool and hits his head against the bottom. When he is rescued, he shows a complete lack of neurologic function below the neck. He is neck still breathing on his own, but he cannot move or own feel his arms and legs. The paramedics carefully legs immobilize his neck for transportation to the hospital, and they alert the emergency department to his impending arrival. – Once there, which treatment would most likely have an immediate benefit for this patient? (other than ABC)
  • 25. • There is some evidence that high- dose corticosteroids administered as soon as possible after the injury will result in a better ultimate outcome
  • 26. Spot 13 • 8 yrs old child resident of Delhi is admitted with fever x 5-6 days, loss of appetite x 6 days and hepato splenomegaly. His peripheral smear is shown above – Spot the picture (name the form of parasite) – Name of the culture media – Drugs used to treat resistant cases
  • 27. • Kala Azar (LD bodies-Amastigote form, form non flagelated form) • NNN media (Novy, MacNeil & Nicolle) • AMB, Pentamidine, Aminosidine, Miltefosine, Recombinant INF gamma, Allopurinol and adjunct splenectomy
  • 28. Spot 14 2 month old male, "fussy", diarrhea and vomiting; flatulence. Breast-fed. He had Viral gastroenteritis 10 days previously. Before the infection, mother's milk was well tolerated. Body weight within normal limits. Moderately dehydrated. Urine shows presence of reducing sugars. No reaction for glucose. You make a diagnosis of lactose intolerance and start him on reduced lactose diet.. • Indications for changing diet in case of non or poor response • What are diet A, B and C
  • 29. • Indications – Stool frequency >10 watery stool/day even after 48 hrs of starting diet – Return of the signs of dehydration any time after staring diet – Failure to establish wt,gain by 7th day of dietary management • Types of diet – Diet A (reduced lactose) – Diet B (lactose free) – Diet C (Monosaccharide diet)
  • 30. Spot 15 2 yr old male child presented with diarrhea of 3 wks duration with failure to thrive. He was started with nutrition rich feeds (Simyl-MCT drops, HMF sachet and pedia sure) and antibiotics at a sure peripheral health center 7 fays back. Since then diarrhoea has even increased and patient is loosing weight. He was Moderately dehydrated at admission. His daily stool output comes around 185 ml and his stool Na+ 42 mEq/L and K+ 3.8 mEq/L. Sister didn’t sent the stool pH and mEq/L reducing substance. What is the diagnosis based on these investigations Calculate the osmotic Gap What is the treatment next
  • 31. • Chronic diarrhoea (Secondary lactose intolerance- Osmotic diarrhoea) diarrhoea • Osmotic Gap : 290-(2 x Stool Na+K) If Gap >100 its osmotic diarrhoea • Remove the osmotic load from the diet and stop feeding for 24 hrs and then restart the lactose free diet without adding any nutritional stuff
  • 32. http://groups.yahoo.com/group/PediatricsDNB/ Theory: http://dnbpediatricstheory.blogspot.in/ OSCE: http://oscepediatrics.blogspot.in/ Clinical: http://clinicalpediatrics.blogspot.in/ Practicals: http://practicalpediatrics.blogspot.in/ Download at: http://www.4shared.com/folder/t8E_yjDv/_online.html