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Oh, the Aching Backs!

Low Back Pain:
Eric Robertson, PT,
A Current State ofK.AffairsDPT, OCS
Eric Robertson, PT, DPT, OCS, FAAOMPT
University of Texas at El Paso Continuing Education Series, Spring 2014
Our Objectives
 Review current epidemiology of LBP

 Review current clinical guidelines for managing patients with
LBP

 Discuss psychologically informed practice as it relates to
patients with LBP

 Discuss optimal care pathways for patients with LBP
Relative Healthcare Costs
Cost in Billions
800
700

600
500
400
300
200
100
0

Cardiovascular
Disease
Relative Healthcare Costs
Cost in Billions
350
300

Cardiovascular
Disease

250

200
150
100
50
0

Cancer

Diabetes

LBP

All Arthritis
Relative Healthcare Costs
Cost in Billions
800
700

CHRONIC PAIN!

600
500
400
300
200
100
0

Cardiovascular
Disease
Which of the following are predictors of LBP?
• Bulging disc without
herniation or root
contact
• Bulging disc without
herniation but with
nerve root contact
• Herniated/Prolapsed
discs
• End plate changes /
Shmorl‘s nodes
• Foraminal or canal
stenosis

Physical findings
/ Imaging

• History of depression
• History of
occupational-related
LBP
• Fearful beliefs about
work as reported in a
survey

Psychosocial
findings
How did you do?
 Physically:
 Only disc contact with nerve root has been shown
to be a WEAK predictor of LBP
 Psychosocial:
 Depression, occupational injuries, and fearavoidance are all STRONG predictors of LBP
Implications in terms of pain?
Summary of LBP Predictors ?

Physical

Psychosocial
Guideline Adherence for LBP
Adherent

Non-adherent
Worsening Trends in
the Management
and Treatment of
Back Pain
Malfi et al. JAMA Int Med, 2013

―Despite numerous published
national
guidelines, management of
routine back pain increasingly
has relied on advanced
diagnostic imaging, referrals to
other physicians, and use of
narcotics, with a concomitant
decrease in NSAID or
acetaminophen use and no
change in physical therapy
referrals. With health care costs
soaring, improvements in the
management of back pain
represent an area of potential
cost savings for the health care
system while also improving the
quality of care.‖
Things we know
about LBP:
 Incidence
 Second only to the common cold for reasons to see a doctor

 25% of US population has had back pain within last 3 months at
any given time.
 Common Dx in PT Clinics everywhere!

 Prognosis
 Favorable prognosis for simple, acute LBP!

Di Fabio & Boissonault (1998)
We have a
problem…
According to
Martin, Deyo et al., (2008
JAMA)

“…spine-related
expenses have risen
exponentially from
1997 – 2005 without
evidence of
improvement of selfassessed health status.”

 Healthcare costs related to low back pain are
climbing

 Outcomes for low back pain are falling
Why?
 Cause of LBP is unclear

 Surgical Interventions

 Imaging

 Chronic LBP costs are high as a sub-group
Evolution of a Paradigm
 Historically, the diagnosis of LBP has closely
matched the tools with which we have had at
our disposal to examine it.
 1900‘s – Nerve etiologies
 1920‘s – Muscle etiologies
 1950‘s – Bony etiologies (radiographs)
 1980‘s – Disc etiologies (MRI) –
 However, this was discovered in 1938!

Back Pain Diagnoses in the 20th Century, Lutz et al., 2003
The percentage of low back pain of a non-specific
nature.
So what about that imaging anyway?
MRI‘s in Healthy Individuals
% of people
120
100
80
60

40
20
0
All Healthy Sign Anatom

HNP

Facet

Combined
Findings on MRI
Do not predict who has LBP in either
the chronic or acute state
• Caragee et al, 2005, 2006; Borenstein et al, 2001; Savage et
al, 1997

Lead to higher rates of surgical
intervention
• Jarvik et al, 2003

Do not predict success or nonsuccess
in rehabilitation or future disability
• Caragee et al, 2005; Kleinsteuck et al, 2006
Inappropriate Imaging?
 66% of CT and MRI ordered by primary MD‘s in an
HMO inapprop.

 28-38% of California workers‘ comp. MRI‘s
inappropriate

 Higher use when MD owns imaging facility

 All imaging tests increased 40% from 2000-2003; now
$100 billion/year
Pharmaceuticals: 180%
increase!

Martin, Deyo et al, JAMA, 2008
Deyo R, AAOMPT 2009
Deyo R, AAOMPT 2009
Spinal Instability?
 "Spinal instability is routinely given as a diagnosis
to these patients with chronic lower-back pain. It
is a term used to justify an operation. And it‗s a
great diagnosis, because it can't be directly
disproved."
Deyo R, AAOMPT
Spinal Fusion Surgery

Annual number of spinal-fusion operations rose by 77 percent
between 1996 and 2001. In contrast, TKA and THA increased by 13 to
14 percent during the same interval
Spinal-Fusion Surgery - The Case for Restraint
Deyo RA et al. NEJM. 2004 350, Iss. 7; 722
Financial Interests in Spine
Surgery
Pedicle Screws at $13,000 per instrumented
fusion surgery.
• $4 billion per year!

Manufactures acknowledge giving surgeons
millions in royalties, speaking fees, and research
grants.
• On-going government investigation of device makers

Government investigating illegal kickbacks.
• Medtronic paid $40million in settlement

Ableson R, Peterson M; New York Times, 2003
Quote:
Dr. Seth Waldman:

 "There will be a lot of people doing the wrong
thing for back pain for a long time, until we finally
figure it out. I just hope that we don't hurt too
many people in the process."
Clinical
Guidelines
Diagnosis and Treatment of Low Back Pain: A
Joint Clinical Practice Guideline from the
American College of Physicians and the
American Pain Society. Chou et al., 2007
Clinical Guideline: APS - APC
Chou et al., 2007 Annals of Internal Medicine
Clinical Guideline: APS - APC
Chou et al., 2007 Annals of Internal Medicine
Clinical Guideline: APS - APC
Chou et al., 2007 Annals of Internal Medicine
Clinical Guideline: APS - APC
Chou et al., 2007 Annals of Internal Medicine
Clinical Guideline: APS - APC
Chou et al., 2007 Annals of Internal Medicine
Clinical Guideline: APS - APC
Chou et al., 2007 Annals of Internal Medicine

•Spinal Manipulation

•Exercise
•Yoga
•Acupuncture
•CBT
•Spinal manipulation
635 Billion Reasons
Or, why addressing chronic pain is in everyone’s best
interest.
PAIN
#1 cause of adult
disability in the US
PAIN
1 in 6 People live with
chronic pain.
PAIN
Total annual direct
costs for pain >$635B.
Relative Healthcare Costs
Cost in Billions
350
300

Cardiovascular
Disease

250

200
150
100
50
0

Cancer

Diabetes

LBP

All Arthritis
Relative Healthcare Costs
Cost in Billions
800
700

CHRONIC PAIN!

600
500
400
300
200
100
0

Cardiovascular
Disease
Summary of LBP Predictors ?

Physical

Psychosocial
Implications in terms of pain?
 It might not be as much of a
physical thing as we think!

 We need to consider the
cognitive components!
Nociception
Nociceptive Input
Mechanical /
Proprioceptive Input

C/Adelta
A-beta

T-Cells
Signal in 2nd order Neurons
dominated by A-beta input
Nociception
Noci means danger! Detecting danger.
All the way to thalmus is nociception. The
thalmus is determining what should we tell
the brain
 Nociception can activate protective
responses without us knowing about it…think
withdrawal reflex from a hot stove

Nociception is NOT Pain Perception.
The perception of pain
creates pain!
CRPS EXAMPLE Neurology, 2005- touching a
mirror image of the non-painful hand creates
pain and swelling in the painful side.
The perception of pain
creates pain!
Also:
 Phantom limb pain
 Severity of Whiplash inversely related to initial
pain perception
 Battlefield injuries: little pain reported
 So…you don‘t need nociception to feel pain.
Nociception

Pain

Outside of
awareness

Aware

Input
Small picture

Without emotion

Relatively Simple

Output
Big picture
With emotion
Relatively
Complex

Pain the conscious version of nociception
Pain is…

Modern Pain Model: The Neuromatrix Paradigm
 Nociceptive signals are processed in the
brain, mixed with other
sensory, emotional, cognitive, planning, and motor
signals in the brain, and the resultant output is the
pain perception.
How do we change pain
perception?

What can we change
 Sensory input from body
 Social work environment
 Expected consequences
 Beliefs, knowledge

What can’t we change
 Previous experience
 Cultural Factors
Chronic Pain Models

 We speak of pain processing primarily in terms of
acute pain.
Physical

 Pain that persists beyond nociceptive input is
difficult to understand if you forget that pain is an
output.

 Chronic pain models can influence the way we
treat patients.

Psychosocial
Concept: The Body-self

Large loops of neurons between the
thalamus and the cortex which allow parallel
processing and permit:
 An awareness of the body and unique and
separate from the world
 An orientation of the self as a point of awareness
Neuromatrix Paradigm
 The collection of structures creating the body-self is
called the neuromatrix.

 The continuous output from this system is a
neurosignature

 The neurosignature is always present and allows us
to perceive normal

 We detect when it‘s abnormal = pain
Melzack, Acta Anaesthesiol Scand 1999; 43: 880–884
Neuromatrix Paradigm
 Explains how pain can be felt without
nociception

 Explains chronic pain

 Explains how the brain changes in response to
pain
 Up-regulation, increased receptor fields, more
efficient pain processing
Neuromatrix Paradigm

BodySelf

Pain?
57

From: Gifford, LS 1998
Identifying Patients at Risk for
Chronic Pain
Originally:
 Waddell‘s Non-organic Signs and Symptoms

Bottom Line:

•None of the non-organic tests served as
effective screening measures to predict
development of chronic LBP
•Alternative screening tools are required
Fritz et al., 2000
Identifying Patients at Risk for
Chronic Pain
George & Zepperi, JOSPT, July- 2009

 Fear-avoidance model of musculoskeletal pain
(FAM) (Measured by FABQ)
 Factors influencing pain perception
 Anxiety
 Fear of re-injury
 Catastrophizing

Confrontation
Anxiety
Fear of re-injury
Catastrophizing

Avoidance
Anxiety
Fear of re-injury
Catastrophizing
Graded Exposure for Patients
with Chronic Pain

George & Zepperi, JOSPT, July2009
L E V E L
P A I N

Injury!
Adapted from Butler & Mosely, 2008, ―Explain Pain‖

H E A L I N G

R E S P ON SE
FDAQ – A Measurement

George & Zepperi, JOSPT, July- 2009
George et al., PTJ, July- 2009
General Principles

1.

Chronic pain is not a local anatomical problem.

2. Pain perception influenced by common psychological
conditions (FAB, depression).
General Principles

3. True psychogenic causes of pain are so rare as to not even be
discussed much in rehab settings. Most patients we see have a
reason to have pain (i.e. injury) and it is the processing of the
pain that is altered.

4. Overt malingering is rare and cannot be detected by physical
therapists (i.e. variation in maximum effort does not equal lack
of effort).
General Principles

5. Graded approaches are a good way for PT's to incorporate
cognitive-behavioral principles. The key is to focus on activity
tolerance, NOT pain reduction.

6. If you are seeing a lot of chronic pain, consider a
multidisciplinary approach, as that is where the evidence points
to increased effectiveness.
Establishing a Baseline
Therapist: ‗How long can you walk before you flare-up?‘
Patient: ‗I can walk for 30 min but I pay for it the next day‘
Therapist: ‗Can you walk for 20 min without flaring up?‘
Patient: ‗No, but I have‘
Therapist: ‗Can you walk for 10 min without flaring up?‘
Patient: ‗Probably not — definitely not up hills‘
Therapist: ‗5 min on a flat surface?‘
Patient: ‗Probably‘

Therapist: ‗3 min on a flat surface?‘
Patient: ‗Definitely‘
Continuous Progression
 ‗every day you do more than you did
yesterday, but not much more‘…at least initially.
 Setting clear measurable goals and objectives!
KEY POINTS
 Pain is not nociception
 The representation of the body in the human brain
 The brain changes as the pain persists
 Body-brain is a 2 way street

 Training the brain for people in Pain
Patient Education
Perhaps your most powerful analgesic
tool is the ability to educate your patient
about pain physiology.

Physical Therapists
We are the intersection of physiology &
psychology!
A = Baseline
Chronic Pain

B = Following
HEP

C = Following
Pain
Education
One more thing…
Is spinal manipulation appropriate for people with chronic pain?
Response to Thoracic Spine
Manipulation: fMRI
Pre-Manipulation

Post-Manipulation

Sparks et al, JOSPT 2013
Timing of Referral and
Adherence to Best Practice
for LBP:
Does It Matter?
John D. Childs, PT, PhD, MBA
Non-invasive Interventions for Acute
LBP
Intervention

Net benefit

Level of evidence

Spinal manipulation

Small/Moderate

Fair

Exercise therapy

No benefit

Good

Back schools

Unclear

Poor

Acupuncture

Unclear

Poor

Massage

Unclear

Poor

Interferential therapy, shortwave diathermy, ultrasound,
lumbar supports, TENS

Unclear

Poor
Non-invasive interventions for Chronic or Subacute
LBP
Intervention

Net benefit

Level of evidence

Behavioral therapy

Moderate

Good

Exercise therapy

Moderate

Good

Interdisciplinary
rehabilitation

Moderate

Good

Spinal manipulation

Moderate

Good

Acupuncture

Moderate

Fair

Massage

Moderate

Fair

Yoga

Moderate

Fair (for Viniyoga)

Back schools

Small

Fair
Arch Intern Med. 2010;170(3):271-277
Methods
• Care provided in 3,533 patient visits to GPs for a
new episode of LBP was mapped to key
recommendations in treatment guidelines
• The proportion of patient encounters in which care
arranged by a GP aligned with these key
recommendations was determined for the period
2005 through 2008 and separately for the period
before the release of the local guideline in 2004
(2001-2004)
Results
• Despite recommendations to the contrary
• > 25% patients referred for imaging
• Only 20.5% and 17.7% received care limited to advice
and simple analgesics, respectively
• Analgesics provided were typically NSAIDs (37.4%) and opioids
(19.6%)

• This pattern of care was the same in the periods
before and after the release of the local guideline
The timing of care
matters.
2011;41(11):838846

Fuhrmans V. A Novel Plan Helps Hospital Wean Itself Off Pricey Tests. WSJ. 2007:1/12.
Methods
• National 20% sample of CMS outpatient claims
(Medicare)
• Treatment for LBP between 2003-2004 (n=439,195).

• Patients with prior visit for back pain, lumbosacral
injection, or lumbar surgery within the previous
year were excluded
• Referral to physical therapy classified as
• Acute – 0-4 weeks
• -Subacute – 4 weeks – 3 months
• Chronic – 3 months – 1 year
Gellhorn et al. 2012; 37: 775 – 782

0.47 (95% CI, 0.44–0.50)

0.46 (95% CI, 0.44–0.49)

0.38 (95% CI, 0.36–0.41)

There was a lower risk of subsequent medical
service among patients who received PT early
after an episode of acute LBP relative to those
who received PT later.
Purpose
• Examine the cost implications of the decision to
refer patients with a new episode of LBP from
primary care providers to physical therapy and
examine the influence of the timing of referral
(early vs. delayed) and the content of the care
(adherent vs. non adherent) received by physical
therapists
Subjects
SETTING
Data extracted from Mercer
HealthOnline® a database of
members of employeesponsored health plans.
Subjects
32,070 patients with a new primary care consultation for
LBP from November 1, 2007 - January 31, 2009.
756.11 Spondylolysis, lumbosacral region
756.11 Spondylolesthesis

722.1 Lumbar disk displacement

722.93 Other disk disorder lumbar region

846.0 Sprain lumbosacral

722.73 Lumbar disk deease with myelopathy

846.8 Sprain – other sacroilliac region

721.3 Lumbosacralspondylosis without myelopathy

846.1 Sprain sacroilliac
,sprain - sacrum

722.52 Lumbar / lumbosacral disc displacement

724.02 Spinal stenosis - lumbar

724.5 Backache, unspecified

847.2 Sprain lumbar region

847.3 sprain other specified sites of sacroiliac region

724.3 Sciatica

724.4 Thoracic or lumbosacral neuritis or radiculitis

724.3 Lumbago
Data Abstraction
• Patients meeting definition of new LBP episode visiting a
primary care provider from November 1, 2007 through
January 31, 2009

• Eligible patients had to be continuously eligible within the
database for 6 months before and 18 months after the index
date
• All healthcare visits, procedures, tests, prescription
medications, etc. and associated billed charges
• CPT codes for each visit if patient received physical therapy
Inclusion/Exclusion
• Age 18-60 years old at index primary care visit
• No prior spinal surgery
• No evidence of non-musculoskeletal cause of LBP
diagnosis (e.g., infectious process, kidney
stones, gall stones, urinary tract
infection, cancer, osteomyelitis, etc.)
Groups
Timing:
1. Early Physical Therapy - 1-14 days from first Dr. visit
(53%)
2. Delayed Physical Therapy - 15-90 days (47%)
Content:
1. Adherent - Active physical therapy based on CPT
codes (22%)
2. Non adherent – Passive physical therapy (78%)
Covariates Examined
• Age and gender
• Amount of co-payment for the index visit
• Insurance plan (Point-of-service, Preferred Provider
Organization, Health Maintenance Organization , High
deductible health plan, Other)
• Employment status (Active, Retiree, Long-term
disability, Other)
• Geographic region (Northeast, South, Midwest, West)
Comorbidities
• Co-morbid healthcare conditions in 6-month period prior to index date
• Number unique ICD-9 diagnoses recorded in any setting
• Number of unique medications
• If a hospitalization occurred
• If narcotic medications were prescribed
• Total allowed costs for all services (inpatient, outpatient and
prescription)
• Presence of co-morbid health conditions that may influence prognosis
for individuals with LBP
• Mental health conditions (depression, anxiety, bipolar or other
psychotic disorders)
• Concomitant neck or thoracic spine pain
• Fibromyalgia
Phase 1: 1st 14 days of Episode of Care
ACTIVE CODES
97110
97350
97535

Therapeutic
Exercise
Therapeutic
Activity
Self Care
Management
Training

PASSIVE CODES

ALLOWED CODES
PT
Evaluation
PT ReEvaluation

97035

Ultrasound

97001

97010

Hot or Cold
Pack

97002

G0283,
97032

Electrical
Stimulation

99070

Miscellaneo
us Supplies

97112

Neuromuscul
ar Re97012
Education

Mechanical
Traction

97750

Physical
Performanc
e
Test/Measu
re

97150

Group
Therapeutic
Procedures

Massage
Therapy

97140

Manual
Therapy

PHASE I

97124

97113

97116

Aquatic
Therapy
with
Exercise
Gait
Training
Therapy
Phase 2: >14 days
ACTIVE CODES
97110
97350
97535

PHASE II

PASSIVE CODES

Therapeutic
97140
Exercise
Therapeutic
97035
Activity
Self Care
Management 97010
Training

ALLOWED CODES

Manual
Therapy

97001

Ultrasound

97002

Hot or Cold
Pack

99070

97112

Neuromuscul
G0283,
ar Re97032
Education

Electrical
Stimulation

97750

97150

Group
Therapeutic
Procedures

97012

Mechanical
Traction

97113

97124

Massage
Therapy

97116

PT
Evaluation
PT ReEvaluation
Miscellaneo
us Supplies
Physical
Performanc
e
Test/Measu
re
Aquatic
Therapy
with
Exercise
Gait
Training
Therapy
Determination of Adherence
• Number of active and passive CPT codes at each visit within
each phase recorded
• % of active to passive codes calculated as
• Number of active codes/(number of active codes + number of
passive codes) x 100%

• Adherent care defined as % of active to passive codes at
least 75%, with each visit including at least 1 active code
• Comparisons of costs between adherent vs. non-adherent
care
All Patients
(n=32,070)

Timing of Physical
Therapy (n=2,077)
Early
Delayed
(n=1,102) (n=975)

Content of Physical
Therapy (n=1,917)
NonAdherent Adherent
(n=413) (n=1504)

Advanced
Imaging (MRI
or CT)

18.9%

29.4%

54.9%

38.7%

43.9%

Physician
Specialist Visits

44.1%

52.6%

81.0%

64.4%

68.8%

Lumbar Spine
Surgery

2.5%

4.7%

9.9%

5.1%

8.1%

Lumbar Spinal
Injections

7.1%

10.1%

21.2%

12.6%

17.8%

Narcotic
49.1%
Medication Use

49.1%

55.3%

49.6%

53.2%

Table 2. Utilization of specific services for low back pain in the 18
month period following the index primary care visit
All Patients
(n=32,070)

Timing of Physical
Therapy (n=2,077)
Early
(n=1,102)

Delayed
(n=975)

Content of Physical
Therapy (n=1,917)
NonAdherent
Adherent
(n=413)
(n=1504)

Imaging
Procedures

$291.12
(5.42)

$473.32 $807.20 $513.84 $701.14
(63.92) (42.12) (46.82) (52.32)

Physician Visits

$209.54
(1.48)

$259.62 $411.76 $295.52 $357.15
(9.76)
(11.89) (14.33)
(9.86)

Surgical/
Injection
Procedures

$740.44 $1018.88 $2760.62 $1445.23 $1965.72
(36.84) (170.65) (381.27) (486.37) (229.42)

Inpatient NonSurgical
Procedures

$79.28
(11.13)

$65.00
(30.58)

$231.79 $162.31 $142.99
(64.52) (90.20) (37.81)

Table 3. Costs incurred over the 18 month period following the index
primary care visit. Values represent mean (standard error).
All
Patients
(n=32,070)

Timing of Physical
Therapy (n=2,077)
Early
Delayed
(n=1,102) (n=975)

Content of Physical
Therapy (n=1,917)
Adherent Non-Adherent
(n=413)
(n=1504)

Emergency Room
Visits

$19.83
(0.87)

$26.21
(4.89)

$25.22
(4.59)

$24.87
(6.94)

$28.61
(4.36)

Prescription
Medication

$104.23
(3.01)

$80.41
(10.22)

$116.83
(11.27)

$76.43
(9.85)

$98.85
(9.61)

Other LBP-related $437.89 $1225.04 $1531.3 $1090.64
Costs
(8.11) (52.10) (67.01) (89.06)

$1651.73
(53.07)

Total LBP costs

$1882.33 $3148.49 $5884.71 $3608.83
(44.58) (228.90) (429.92) (533.49)

$4946.18
(277.19)

Non-LBP
healthcare costs

$7892.53 $7169.22 $8430.44 $7254.82
(108.75) (472.39) (761.80) (1155.66)

$7511.44
(402.09)

Table 3. Costs incurred over the 18 month period following the index
primary care visit. Values represent mean (standard error).
Utilization of Services
Early PT

Delayed PT

53%

81%

49%

55%

10%

21%

4.7%

9.9%

29%

55%
Figure 2. Likelihood of receiving specific services during the 18 month
follow-up period based on non adherent physical therapy care.
$3,000.00

Total Costs:
$2,500.00

$3148
$5884

$2,000.00

$1,500.00

$1,000.00

$500.00

$0.00

Early PT
Delayed PT
Total Costs:
$7,000

$3148
$5884

$6,000

Other LBP-related Costs

$5,000

Prescription Medication
Emergency Room Visits
$4,000

Inpatient Non-Surgical Procedures
Surgical/ Injection Procedures

$3,000

Physician Visits
Imaging Procedures

$2,000

$1,000

$0

Early Physical Therapy

Delayed Physical Therapy
Implications of Timing and Quality of Physical
Therapy on Low Back Pain Utilization and Costs in
the Military Health System
John D. Childs, PT, PhD, MBA
Samuel S. Wu, PhD
Eric Robertson, PT, DPT
Forest S. Kim PhD, MHA, MBA
Robert S. Wainner, PT, PhD
Timothy W. Flynn, PT, PhD
Steven Z. George, PT, PhD
Julie M. Fritz, PT, PhD
Background
• Back pain & arthritis the most costly conditions requiring rehabilitation
in the U.S.
• Over $200 billion per year, exceeding total costs associated with spinal cord
injury, traumatic brain injury, stroke, multiple sclerosis, and limb loss

• Studies demonstrate that the vast majority of costs are incurred early in
the care process
• Many studies demonstrate lack of adherence to practice guidelines for
managing LBP
• Previous work has demonstrated that timing of referral and adherence
to practice guidelines reduces utilization and costs
• Military Health System offers compelling opportunity to expand this
work because a single payer system
Methods
• Extract LBP ICD-9 codes from Jan 1, 2007 through Dec 31, 2009

• Extract full history of these cases from Jan 1, 2006-Dec 31, 2011
• Determine previous medical history for 1-year preceding the index visit
• Conduct 2-year follow-up from index visit

• Newly consulting LBP defined as no claims with a LBP-related
ICD-9 code for 6 months preceding the index date
Inclusion/Exclusion
• Age between 18-60 years of age at index date
• Continuously eligible within database 12 months before (to capture comorbidities and previous history) and 24 months after index date
• No co-morbid diagnosis within 4 weeks of index date that could be
nonmusculoskeletal source of LBP (e.g, kidney stones, urinary tract
infection, etc .)
• No prior history of spinal surgery or trauma (ie. fx) based on the
presence of related current procedural terminology (CPT) codes at any
time prior to the index date
• Only the first eligible index date for an individual patient included to
avoid overlap in episodes of care. (ie – individual patients can only
appear once in dataset)
Analysis
• Considered 90-day period after the primary care index date to identify PT
utilization
• If a PT visit occurred with a LBP-related ICD-9 during this period, patient
defined as utilizing PT
• Early PT defined as utilizing PT within 14 days from primary care index date
• All PT episodes without a primary care index date (ie, direct access) classified
as early
• Late PT defined as utilizing PT between 15-90 days from index date

• Patients with both PT and chiropractic utilization for LBP excluded
• Adherence determined using the same algorithm previously published
(Fritz, Spine, 2012)

• Controlled for co-morbidities similar to previous research
(Fritz, Spine, 2012)
Inclusion and
Exclusion
Criteria

883,969 continuously eligible
patients with primary care for low
back pain.
Age <18 & >60 years
(n=13,992)
Low back pain claim in the
past 6 months (n=38,955)

Possible nonmusculoskeletal low back
pain (n=154,729)
Prior surgery for low back
pain (n=148)

676,145 patients included in
analysis
Groups and Demographics

Age (mean, sd)

Gender (% female)
Common Beneficiary Category
Spouse/families
Retired
Other
Active Duty

Timing of PT
Adherence
All
PT Users
Adheren
Patients
Early Delayed
Non‐Adher
(n=158,2
t
(n=676,14
(n=59,4 (n=98,8
ent
(n=23,5
71)
16)
55)
5)
(n=32,750)
50)
33.8
33.3
32.2
34.0
34.8
36.1
(11.2)
(10.5)
(10.4) (10.6) (11.3)
(11.2)
39.10% 34.10% 32.80% 34.90% 41.80% 45.30%
19.80%
10.10%
12.80%
57.30%

14.50% 13.10% 15.30% 20.60%
7.30% 5.80% 8.10% 11.20%
8.80% 8.00% 9.30% 13.20%
69.50% 73.10% 67.20% 55.00%

22.80%
11.70%
14.90%
50.70%
Additional Covariates
Timing of PT
All Patients PT Users
Early
Delayed
(n=676,145 (n=158,271
(n=59,416 (n=98,855
)
)
)
)
Number of LBP diagnosis codes
1.5
1.4
1.4
1.4
(mean, sd)
(1.8)
1.5)
(1.2)
(1.6)
Number of prescription
13.6
15.2
12.9
16.5
medications
(10.3)
(10.8)
(9.9)
(11.0)
(mean, sd)
Co‐morbid mental health condition
0.082
0.084
0.078
0.088
Co‐morbid fibromyalgia diagnosis
0.019
0.017
0.016
0.018
Co‐morbid neck/thoracic spine
0.108
0.118
0.129
0.111
condition
Narcotic use prior to index visit 34.10%
35.20%
34.10%
35.90%
Hospitalization prior to index visit 7.20%
7.10%
6.90%
7.20%
Total medical costs prior to index
$3608.26 $3704.36 $3617.90 $3756.35
visit
(8017.10) (7795.80) (8189.26) (7548.91)
(mean, sd)

Adherence
Adherent Non‐Adhere
(n=23,550
nt
)
(n=32,750)
1.5
1.7
(1.7)
(1.9)
15.9
(11.1)

16.4
(11.3)

0.09
0.02

0.088
0.023

0.116

0.142

37.50%
8.40%
$4119.76
(10271.64
)

38.40%
8.50%
$4069.42
(7558.78)
Adjusted Odds Ratios & 99% CIs

Advanced Imaging

E vs. D
.47 (.45, .49)

A vs. NA

.68 (.64, .72)

Lumbar surgery

.52 (.47, .56)

.80 (.71, .91)

Spinal injection

.47 (.45, .49)

.78 (.73, .83)

Opioid use

.48 (.47, .50)

.93 (.89, .98)
Utilization of Services – Timing of Care
Early

Delayed

Advanced imaging
(MRI or CT)

12%

23%

Lumbar spine
surgery

3%

4%

8%

17%

59%

75%

Lumbar spinal
injections

Opioid medication
use
Utilization of Services – Guideline Adherence
Adherent Non-adherent
Advanced
imaging
(MRI or CT)

Lumbar spine
surgery
Lumbar spinal
injections

Opioid
medication
use

23%

30%

2%

4%

14%

18%

71%

73%
Utilization of Services – Timing & Guideline
Adherence
E/A E/NA D/A D/NA
Advanced
imaging
(MRI or CT)
Lumbar spine
surgery

Lumbar spinal
injections
Opioid
medication
use

13%

20%

27%

35%

2%

3%

4%

5%

9%

13%

17%

21%

61%

64%

77%

78%
Total Costs Incurred Over 2-year
Follow-up
$1,400
$1,200

$859

$1,000
$800

$733

$983

$600
$400
$200
$0

Prescription meds
E/A

E/NA

L/A

L/NA

$1,145
Total Costs Incurred Over 2-year
Follow-up
$16,000
$14,000
$12,000

$11,407

$13,030
$10,521

$10,000
$8,000
$6,000
$4,000

$2,000
$0

Inpatient
E/A

E/NA

L/A

L/NA

$13,506
Total Costs Incurred Over 2-year
Follow-up
$5,000

$4,340

$4,500

$3,670

$4,000
$3,500

$2,784

$3,000
$2,500

$2,110

$2,000
$1,500
$1,000
$500
$0

Total LBP
E/A

E/NA

L/A

L/NA
Total Costs Incurred Over 2-year
Follow-up
$12,000
$10,000

$10,380
$8,470

$8,459

$8,000
$6,000
$4,000
$2,000
$0

Non LBP-related
E/A

E/NA

L/A

L/NA

$10,589
Low quality physical
therapy delivered early
is better than current
standard of care for
back pain management
in the U.S.
High quality physical
therapy delivered
early is even better
Acknowledgements
• This study is funded in part by the following
organizations:
• U.S. Air Force Medical Service Intramural Grant
Program
• Texas State University Faculty Grant
References
1. mischvalente. back pain.; 2008. Available at: http://www.flickr.com/photos/mamibodega/2931602556/
[Accessed July 12, 2009].
2. Martin BI, Deyo RA, Mirza SK, et al. Expenditures and health status among adults with back and neck problems.
JAMA. 2008;299(6):656-664.
3. Groupman J. Annals of Medicine: A Knife in the Back: The New Yorker. 2002. Available at:
http://www.newyorker.com/archive/2002/04/08/020408fa_FACT [Accessed July 13, 2009].
4. Deyo RA, Nachemson A, Mirza SK. Spinal-fusion surgery - the case for restraint. N. Engl. J. Med.
2004;350(7):722-726.
5. Deyo R, Mirza S. The case for restraint in spinal surgery: does quality management have a role to play? Eur Spine
J. 2009. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19266220 [Accessed July 14, 2009].
6. Dave. stop back pain.; 2007. Available at: http://www.flickr.com/photos/funkypancake/1478208586/ [Accessed
July 12, 2009].
7. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States
and internationally. Spine J. 2008;8(1):8-20.
8. Chou R, Baisden J, Carragee EJ, et al. Surgery for low back pain: a review of the evidence for an American Pain
Society Clinical Practice Guideline. Spine. 2009;34(10):1094-1109.
9. Chou R, Atlas SJ, Stanos SP, Rosenquist RW. Nonsurgical interventional therapies for low back pain: a review of
the evidence for an american pain society clinical practice guideline. Spine. 2009;34(10):1078-1093.
10. Chou R, Fu R, Carrino JA, Deyo RA. Imaging strategies for low-back pain: systematic review and meta-analysis.
Lancet. 2009;373(9662):463-472.

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LBP Update

  • 1. Oh, the Aching Backs! Low Back Pain: Eric Robertson, PT, A Current State ofK.AffairsDPT, OCS Eric Robertson, PT, DPT, OCS, FAAOMPT University of Texas at El Paso Continuing Education Series, Spring 2014
  • 2. Our Objectives  Review current epidemiology of LBP  Review current clinical guidelines for managing patients with LBP  Discuss psychologically informed practice as it relates to patients with LBP  Discuss optimal care pathways for patients with LBP
  • 3. Relative Healthcare Costs Cost in Billions 800 700 600 500 400 300 200 100 0 Cardiovascular Disease
  • 4. Relative Healthcare Costs Cost in Billions 350 300 Cardiovascular Disease 250 200 150 100 50 0 Cancer Diabetes LBP All Arthritis
  • 5. Relative Healthcare Costs Cost in Billions 800 700 CHRONIC PAIN! 600 500 400 300 200 100 0 Cardiovascular Disease
  • 6. Which of the following are predictors of LBP? • Bulging disc without herniation or root contact • Bulging disc without herniation but with nerve root contact • Herniated/Prolapsed discs • End plate changes / Shmorl‘s nodes • Foraminal or canal stenosis Physical findings / Imaging • History of depression • History of occupational-related LBP • Fearful beliefs about work as reported in a survey Psychosocial findings
  • 7. How did you do?  Physically:  Only disc contact with nerve root has been shown to be a WEAK predictor of LBP  Psychosocial:  Depression, occupational injuries, and fearavoidance are all STRONG predictors of LBP Implications in terms of pain?
  • 8. Summary of LBP Predictors ? Physical Psychosocial
  • 9. Guideline Adherence for LBP Adherent Non-adherent
  • 10. Worsening Trends in the Management and Treatment of Back Pain Malfi et al. JAMA Int Med, 2013 ―Despite numerous published national guidelines, management of routine back pain increasingly has relied on advanced diagnostic imaging, referrals to other physicians, and use of narcotics, with a concomitant decrease in NSAID or acetaminophen use and no change in physical therapy referrals. With health care costs soaring, improvements in the management of back pain represent an area of potential cost savings for the health care system while also improving the quality of care.‖
  • 11. Things we know about LBP:  Incidence  Second only to the common cold for reasons to see a doctor  25% of US population has had back pain within last 3 months at any given time.  Common Dx in PT Clinics everywhere!  Prognosis  Favorable prognosis for simple, acute LBP! Di Fabio & Boissonault (1998)
  • 12. We have a problem… According to Martin, Deyo et al., (2008 JAMA) “…spine-related expenses have risen exponentially from 1997 – 2005 without evidence of improvement of selfassessed health status.”  Healthcare costs related to low back pain are climbing  Outcomes for low back pain are falling
  • 13. Why?  Cause of LBP is unclear  Surgical Interventions  Imaging  Chronic LBP costs are high as a sub-group
  • 14. Evolution of a Paradigm  Historically, the diagnosis of LBP has closely matched the tools with which we have had at our disposal to examine it.  1900‘s – Nerve etiologies  1920‘s – Muscle etiologies  1950‘s – Bony etiologies (radiographs)  1980‘s – Disc etiologies (MRI) –  However, this was discovered in 1938! Back Pain Diagnoses in the 20th Century, Lutz et al., 2003
  • 15. The percentage of low back pain of a non-specific nature.
  • 16. So what about that imaging anyway?
  • 17. MRI‘s in Healthy Individuals % of people 120 100 80 60 40 20 0 All Healthy Sign Anatom HNP Facet Combined
  • 18. Findings on MRI Do not predict who has LBP in either the chronic or acute state • Caragee et al, 2005, 2006; Borenstein et al, 2001; Savage et al, 1997 Lead to higher rates of surgical intervention • Jarvik et al, 2003 Do not predict success or nonsuccess in rehabilitation or future disability • Caragee et al, 2005; Kleinsteuck et al, 2006
  • 19. Inappropriate Imaging?  66% of CT and MRI ordered by primary MD‘s in an HMO inapprop.  28-38% of California workers‘ comp. MRI‘s inappropriate  Higher use when MD owns imaging facility  All imaging tests increased 40% from 2000-2003; now $100 billion/year
  • 23. Spinal Instability?  "Spinal instability is routinely given as a diagnosis to these patients with chronic lower-back pain. It is a term used to justify an operation. And it‗s a great diagnosis, because it can't be directly disproved."
  • 25. Spinal Fusion Surgery Annual number of spinal-fusion operations rose by 77 percent between 1996 and 2001. In contrast, TKA and THA increased by 13 to 14 percent during the same interval Spinal-Fusion Surgery - The Case for Restraint Deyo RA et al. NEJM. 2004 350, Iss. 7; 722
  • 26. Financial Interests in Spine Surgery Pedicle Screws at $13,000 per instrumented fusion surgery. • $4 billion per year! Manufactures acknowledge giving surgeons millions in royalties, speaking fees, and research grants. • On-going government investigation of device makers Government investigating illegal kickbacks. • Medtronic paid $40million in settlement Ableson R, Peterson M; New York Times, 2003
  • 27. Quote: Dr. Seth Waldman:  "There will be a lot of people doing the wrong thing for back pain for a long time, until we finally figure it out. I just hope that we don't hurt too many people in the process."
  • 28. Clinical Guidelines Diagnosis and Treatment of Low Back Pain: A Joint Clinical Practice Guideline from the American College of Physicians and the American Pain Society. Chou et al., 2007
  • 29. Clinical Guideline: APS - APC Chou et al., 2007 Annals of Internal Medicine
  • 30. Clinical Guideline: APS - APC Chou et al., 2007 Annals of Internal Medicine
  • 31. Clinical Guideline: APS - APC Chou et al., 2007 Annals of Internal Medicine
  • 32. Clinical Guideline: APS - APC Chou et al., 2007 Annals of Internal Medicine
  • 33. Clinical Guideline: APS - APC Chou et al., 2007 Annals of Internal Medicine
  • 34. Clinical Guideline: APS - APC Chou et al., 2007 Annals of Internal Medicine •Spinal Manipulation •Exercise •Yoga •Acupuncture •CBT •Spinal manipulation
  • 35.
  • 36. 635 Billion Reasons Or, why addressing chronic pain is in everyone’s best interest.
  • 37. PAIN #1 cause of adult disability in the US
  • 38. PAIN 1 in 6 People live with chronic pain.
  • 39. PAIN Total annual direct costs for pain >$635B.
  • 40. Relative Healthcare Costs Cost in Billions 350 300 Cardiovascular Disease 250 200 150 100 50 0 Cancer Diabetes LBP All Arthritis
  • 41. Relative Healthcare Costs Cost in Billions 800 700 CHRONIC PAIN! 600 500 400 300 200 100 0 Cardiovascular Disease
  • 42. Summary of LBP Predictors ? Physical Psychosocial
  • 43. Implications in terms of pain?  It might not be as much of a physical thing as we think!  We need to consider the cognitive components!
  • 45. Nociceptive Input Mechanical / Proprioceptive Input C/Adelta A-beta T-Cells Signal in 2nd order Neurons dominated by A-beta input
  • 46. Nociception Noci means danger! Detecting danger. All the way to thalmus is nociception. The thalmus is determining what should we tell the brain  Nociception can activate protective responses without us knowing about it…think withdrawal reflex from a hot stove Nociception is NOT Pain Perception.
  • 47. The perception of pain creates pain! CRPS EXAMPLE Neurology, 2005- touching a mirror image of the non-painful hand creates pain and swelling in the painful side.
  • 48. The perception of pain creates pain! Also:  Phantom limb pain  Severity of Whiplash inversely related to initial pain perception  Battlefield injuries: little pain reported  So…you don‘t need nociception to feel pain.
  • 49. Nociception Pain Outside of awareness Aware Input Small picture Without emotion Relatively Simple Output Big picture With emotion Relatively Complex Pain the conscious version of nociception
  • 50. Pain is… Modern Pain Model: The Neuromatrix Paradigm  Nociceptive signals are processed in the brain, mixed with other sensory, emotional, cognitive, planning, and motor signals in the brain, and the resultant output is the pain perception.
  • 51. How do we change pain perception? What can we change  Sensory input from body  Social work environment  Expected consequences  Beliefs, knowledge What can’t we change  Previous experience  Cultural Factors
  • 52. Chronic Pain Models  We speak of pain processing primarily in terms of acute pain. Physical  Pain that persists beyond nociceptive input is difficult to understand if you forget that pain is an output.  Chronic pain models can influence the way we treat patients. Psychosocial
  • 53. Concept: The Body-self Large loops of neurons between the thalamus and the cortex which allow parallel processing and permit:  An awareness of the body and unique and separate from the world  An orientation of the self as a point of awareness
  • 54. Neuromatrix Paradigm  The collection of structures creating the body-self is called the neuromatrix.  The continuous output from this system is a neurosignature  The neurosignature is always present and allows us to perceive normal  We detect when it‘s abnormal = pain Melzack, Acta Anaesthesiol Scand 1999; 43: 880–884
  • 55. Neuromatrix Paradigm  Explains how pain can be felt without nociception  Explains chronic pain  Explains how the brain changes in response to pain  Up-regulation, increased receptor fields, more efficient pain processing
  • 58. Identifying Patients at Risk for Chronic Pain Originally:  Waddell‘s Non-organic Signs and Symptoms Bottom Line: •None of the non-organic tests served as effective screening measures to predict development of chronic LBP •Alternative screening tools are required Fritz et al., 2000
  • 59. Identifying Patients at Risk for Chronic Pain George & Zepperi, JOSPT, July- 2009  Fear-avoidance model of musculoskeletal pain (FAM) (Measured by FABQ)  Factors influencing pain perception  Anxiety  Fear of re-injury  Catastrophizing Confrontation Anxiety Fear of re-injury Catastrophizing Avoidance Anxiety Fear of re-injury Catastrophizing
  • 60. Graded Exposure for Patients with Chronic Pain George & Zepperi, JOSPT, July2009
  • 61. L E V E L P A I N Injury! Adapted from Butler & Mosely, 2008, ―Explain Pain‖ H E A L I N G R E S P ON SE
  • 62. FDAQ – A Measurement George & Zepperi, JOSPT, July- 2009 George et al., PTJ, July- 2009
  • 63. General Principles 1. Chronic pain is not a local anatomical problem. 2. Pain perception influenced by common psychological conditions (FAB, depression).
  • 64. General Principles 3. True psychogenic causes of pain are so rare as to not even be discussed much in rehab settings. Most patients we see have a reason to have pain (i.e. injury) and it is the processing of the pain that is altered. 4. Overt malingering is rare and cannot be detected by physical therapists (i.e. variation in maximum effort does not equal lack of effort).
  • 65. General Principles 5. Graded approaches are a good way for PT's to incorporate cognitive-behavioral principles. The key is to focus on activity tolerance, NOT pain reduction. 6. If you are seeing a lot of chronic pain, consider a multidisciplinary approach, as that is where the evidence points to increased effectiveness.
  • 66. Establishing a Baseline Therapist: ‗How long can you walk before you flare-up?‘ Patient: ‗I can walk for 30 min but I pay for it the next day‘ Therapist: ‗Can you walk for 20 min without flaring up?‘ Patient: ‗No, but I have‘ Therapist: ‗Can you walk for 10 min without flaring up?‘ Patient: ‗Probably not — definitely not up hills‘ Therapist: ‗5 min on a flat surface?‘ Patient: ‗Probably‘ Therapist: ‗3 min on a flat surface?‘ Patient: ‗Definitely‘
  • 67. Continuous Progression  ‗every day you do more than you did yesterday, but not much more‘…at least initially.  Setting clear measurable goals and objectives!
  • 68. KEY POINTS  Pain is not nociception  The representation of the body in the human brain  The brain changes as the pain persists  Body-brain is a 2 way street  Training the brain for people in Pain
  • 69. Patient Education Perhaps your most powerful analgesic tool is the ability to educate your patient about pain physiology. Physical Therapists We are the intersection of physiology & psychology!
  • 70. A = Baseline Chronic Pain B = Following HEP C = Following Pain Education
  • 71. One more thing… Is spinal manipulation appropriate for people with chronic pain?
  • 72. Response to Thoracic Spine Manipulation: fMRI Pre-Manipulation Post-Manipulation Sparks et al, JOSPT 2013
  • 73. Timing of Referral and Adherence to Best Practice for LBP: Does It Matter? John D. Childs, PT, PhD, MBA
  • 74. Non-invasive Interventions for Acute LBP Intervention Net benefit Level of evidence Spinal manipulation Small/Moderate Fair Exercise therapy No benefit Good Back schools Unclear Poor Acupuncture Unclear Poor Massage Unclear Poor Interferential therapy, shortwave diathermy, ultrasound, lumbar supports, TENS Unclear Poor
  • 75. Non-invasive interventions for Chronic or Subacute LBP Intervention Net benefit Level of evidence Behavioral therapy Moderate Good Exercise therapy Moderate Good Interdisciplinary rehabilitation Moderate Good Spinal manipulation Moderate Good Acupuncture Moderate Fair Massage Moderate Fair Yoga Moderate Fair (for Viniyoga) Back schools Small Fair
  • 76. Arch Intern Med. 2010;170(3):271-277
  • 77. Methods • Care provided in 3,533 patient visits to GPs for a new episode of LBP was mapped to key recommendations in treatment guidelines • The proportion of patient encounters in which care arranged by a GP aligned with these key recommendations was determined for the period 2005 through 2008 and separately for the period before the release of the local guideline in 2004 (2001-2004)
  • 78. Results • Despite recommendations to the contrary • > 25% patients referred for imaging • Only 20.5% and 17.7% received care limited to advice and simple analgesics, respectively • Analgesics provided were typically NSAIDs (37.4%) and opioids (19.6%) • This pattern of care was the same in the periods before and after the release of the local guideline
  • 79. The timing of care matters. 2011;41(11):838846 Fuhrmans V. A Novel Plan Helps Hospital Wean Itself Off Pricey Tests. WSJ. 2007:1/12.
  • 80.
  • 81. Methods • National 20% sample of CMS outpatient claims (Medicare) • Treatment for LBP between 2003-2004 (n=439,195). • Patients with prior visit for back pain, lumbosacral injection, or lumbar surgery within the previous year were excluded • Referral to physical therapy classified as • Acute – 0-4 weeks • -Subacute – 4 weeks – 3 months • Chronic – 3 months – 1 year
  • 82. Gellhorn et al. 2012; 37: 775 – 782 0.47 (95% CI, 0.44–0.50) 0.46 (95% CI, 0.44–0.49) 0.38 (95% CI, 0.36–0.41) There was a lower risk of subsequent medical service among patients who received PT early after an episode of acute LBP relative to those who received PT later.
  • 83.
  • 84. Purpose • Examine the cost implications of the decision to refer patients with a new episode of LBP from primary care providers to physical therapy and examine the influence of the timing of referral (early vs. delayed) and the content of the care (adherent vs. non adherent) received by physical therapists
  • 85. Subjects SETTING Data extracted from Mercer HealthOnline® a database of members of employeesponsored health plans.
  • 86. Subjects 32,070 patients with a new primary care consultation for LBP from November 1, 2007 - January 31, 2009. 756.11 Spondylolysis, lumbosacral region 756.11 Spondylolesthesis 722.1 Lumbar disk displacement 722.93 Other disk disorder lumbar region 846.0 Sprain lumbosacral 722.73 Lumbar disk deease with myelopathy 846.8 Sprain – other sacroilliac region 721.3 Lumbosacralspondylosis without myelopathy 846.1 Sprain sacroilliac ,sprain - sacrum 722.52 Lumbar / lumbosacral disc displacement 724.02 Spinal stenosis - lumbar 724.5 Backache, unspecified 847.2 Sprain lumbar region 847.3 sprain other specified sites of sacroiliac region 724.3 Sciatica 724.4 Thoracic or lumbosacral neuritis or radiculitis 724.3 Lumbago
  • 87. Data Abstraction • Patients meeting definition of new LBP episode visiting a primary care provider from November 1, 2007 through January 31, 2009 • Eligible patients had to be continuously eligible within the database for 6 months before and 18 months after the index date • All healthcare visits, procedures, tests, prescription medications, etc. and associated billed charges • CPT codes for each visit if patient received physical therapy
  • 88. Inclusion/Exclusion • Age 18-60 years old at index primary care visit • No prior spinal surgery • No evidence of non-musculoskeletal cause of LBP diagnosis (e.g., infectious process, kidney stones, gall stones, urinary tract infection, cancer, osteomyelitis, etc.)
  • 89. Groups Timing: 1. Early Physical Therapy - 1-14 days from first Dr. visit (53%) 2. Delayed Physical Therapy - 15-90 days (47%) Content: 1. Adherent - Active physical therapy based on CPT codes (22%) 2. Non adherent – Passive physical therapy (78%)
  • 90. Covariates Examined • Age and gender • Amount of co-payment for the index visit • Insurance plan (Point-of-service, Preferred Provider Organization, Health Maintenance Organization , High deductible health plan, Other) • Employment status (Active, Retiree, Long-term disability, Other) • Geographic region (Northeast, South, Midwest, West)
  • 91. Comorbidities • Co-morbid healthcare conditions in 6-month period prior to index date • Number unique ICD-9 diagnoses recorded in any setting • Number of unique medications • If a hospitalization occurred • If narcotic medications were prescribed • Total allowed costs for all services (inpatient, outpatient and prescription) • Presence of co-morbid health conditions that may influence prognosis for individuals with LBP • Mental health conditions (depression, anxiety, bipolar or other psychotic disorders) • Concomitant neck or thoracic spine pain • Fibromyalgia
  • 92. Phase 1: 1st 14 days of Episode of Care ACTIVE CODES 97110 97350 97535 Therapeutic Exercise Therapeutic Activity Self Care Management Training PASSIVE CODES ALLOWED CODES PT Evaluation PT ReEvaluation 97035 Ultrasound 97001 97010 Hot or Cold Pack 97002 G0283, 97032 Electrical Stimulation 99070 Miscellaneo us Supplies 97112 Neuromuscul ar Re97012 Education Mechanical Traction 97750 Physical Performanc e Test/Measu re 97150 Group Therapeutic Procedures Massage Therapy 97140 Manual Therapy PHASE I 97124 97113 97116 Aquatic Therapy with Exercise Gait Training Therapy
  • 93. Phase 2: >14 days ACTIVE CODES 97110 97350 97535 PHASE II PASSIVE CODES Therapeutic 97140 Exercise Therapeutic 97035 Activity Self Care Management 97010 Training ALLOWED CODES Manual Therapy 97001 Ultrasound 97002 Hot or Cold Pack 99070 97112 Neuromuscul G0283, ar Re97032 Education Electrical Stimulation 97750 97150 Group Therapeutic Procedures 97012 Mechanical Traction 97113 97124 Massage Therapy 97116 PT Evaluation PT ReEvaluation Miscellaneo us Supplies Physical Performanc e Test/Measu re Aquatic Therapy with Exercise Gait Training Therapy
  • 94. Determination of Adherence • Number of active and passive CPT codes at each visit within each phase recorded • % of active to passive codes calculated as • Number of active codes/(number of active codes + number of passive codes) x 100% • Adherent care defined as % of active to passive codes at least 75%, with each visit including at least 1 active code • Comparisons of costs between adherent vs. non-adherent care
  • 95. All Patients (n=32,070) Timing of Physical Therapy (n=2,077) Early Delayed (n=1,102) (n=975) Content of Physical Therapy (n=1,917) NonAdherent Adherent (n=413) (n=1504) Advanced Imaging (MRI or CT) 18.9% 29.4% 54.9% 38.7% 43.9% Physician Specialist Visits 44.1% 52.6% 81.0% 64.4% 68.8% Lumbar Spine Surgery 2.5% 4.7% 9.9% 5.1% 8.1% Lumbar Spinal Injections 7.1% 10.1% 21.2% 12.6% 17.8% Narcotic 49.1% Medication Use 49.1% 55.3% 49.6% 53.2% Table 2. Utilization of specific services for low back pain in the 18 month period following the index primary care visit
  • 96. All Patients (n=32,070) Timing of Physical Therapy (n=2,077) Early (n=1,102) Delayed (n=975) Content of Physical Therapy (n=1,917) NonAdherent Adherent (n=413) (n=1504) Imaging Procedures $291.12 (5.42) $473.32 $807.20 $513.84 $701.14 (63.92) (42.12) (46.82) (52.32) Physician Visits $209.54 (1.48) $259.62 $411.76 $295.52 $357.15 (9.76) (11.89) (14.33) (9.86) Surgical/ Injection Procedures $740.44 $1018.88 $2760.62 $1445.23 $1965.72 (36.84) (170.65) (381.27) (486.37) (229.42) Inpatient NonSurgical Procedures $79.28 (11.13) $65.00 (30.58) $231.79 $162.31 $142.99 (64.52) (90.20) (37.81) Table 3. Costs incurred over the 18 month period following the index primary care visit. Values represent mean (standard error).
  • 97. All Patients (n=32,070) Timing of Physical Therapy (n=2,077) Early Delayed (n=1,102) (n=975) Content of Physical Therapy (n=1,917) Adherent Non-Adherent (n=413) (n=1504) Emergency Room Visits $19.83 (0.87) $26.21 (4.89) $25.22 (4.59) $24.87 (6.94) $28.61 (4.36) Prescription Medication $104.23 (3.01) $80.41 (10.22) $116.83 (11.27) $76.43 (9.85) $98.85 (9.61) Other LBP-related $437.89 $1225.04 $1531.3 $1090.64 Costs (8.11) (52.10) (67.01) (89.06) $1651.73 (53.07) Total LBP costs $1882.33 $3148.49 $5884.71 $3608.83 (44.58) (228.90) (429.92) (533.49) $4946.18 (277.19) Non-LBP healthcare costs $7892.53 $7169.22 $8430.44 $7254.82 (108.75) (472.39) (761.80) (1155.66) $7511.44 (402.09) Table 3. Costs incurred over the 18 month period following the index primary care visit. Values represent mean (standard error).
  • 98.
  • 99. Utilization of Services Early PT Delayed PT 53% 81% 49% 55% 10% 21% 4.7% 9.9% 29% 55%
  • 100. Figure 2. Likelihood of receiving specific services during the 18 month follow-up period based on non adherent physical therapy care.
  • 102. Total Costs: $7,000 $3148 $5884 $6,000 Other LBP-related Costs $5,000 Prescription Medication Emergency Room Visits $4,000 Inpatient Non-Surgical Procedures Surgical/ Injection Procedures $3,000 Physician Visits Imaging Procedures $2,000 $1,000 $0 Early Physical Therapy Delayed Physical Therapy
  • 103. Implications of Timing and Quality of Physical Therapy on Low Back Pain Utilization and Costs in the Military Health System John D. Childs, PT, PhD, MBA Samuel S. Wu, PhD Eric Robertson, PT, DPT Forest S. Kim PhD, MHA, MBA Robert S. Wainner, PT, PhD Timothy W. Flynn, PT, PhD Steven Z. George, PT, PhD Julie M. Fritz, PT, PhD
  • 104. Background • Back pain & arthritis the most costly conditions requiring rehabilitation in the U.S. • Over $200 billion per year, exceeding total costs associated with spinal cord injury, traumatic brain injury, stroke, multiple sclerosis, and limb loss • Studies demonstrate that the vast majority of costs are incurred early in the care process • Many studies demonstrate lack of adherence to practice guidelines for managing LBP • Previous work has demonstrated that timing of referral and adherence to practice guidelines reduces utilization and costs • Military Health System offers compelling opportunity to expand this work because a single payer system
  • 105. Methods • Extract LBP ICD-9 codes from Jan 1, 2007 through Dec 31, 2009 • Extract full history of these cases from Jan 1, 2006-Dec 31, 2011 • Determine previous medical history for 1-year preceding the index visit • Conduct 2-year follow-up from index visit • Newly consulting LBP defined as no claims with a LBP-related ICD-9 code for 6 months preceding the index date
  • 106. Inclusion/Exclusion • Age between 18-60 years of age at index date • Continuously eligible within database 12 months before (to capture comorbidities and previous history) and 24 months after index date • No co-morbid diagnosis within 4 weeks of index date that could be nonmusculoskeletal source of LBP (e.g, kidney stones, urinary tract infection, etc .) • No prior history of spinal surgery or trauma (ie. fx) based on the presence of related current procedural terminology (CPT) codes at any time prior to the index date • Only the first eligible index date for an individual patient included to avoid overlap in episodes of care. (ie – individual patients can only appear once in dataset)
  • 107. Analysis • Considered 90-day period after the primary care index date to identify PT utilization • If a PT visit occurred with a LBP-related ICD-9 during this period, patient defined as utilizing PT • Early PT defined as utilizing PT within 14 days from primary care index date • All PT episodes without a primary care index date (ie, direct access) classified as early • Late PT defined as utilizing PT between 15-90 days from index date • Patients with both PT and chiropractic utilization for LBP excluded • Adherence determined using the same algorithm previously published (Fritz, Spine, 2012) • Controlled for co-morbidities similar to previous research (Fritz, Spine, 2012)
  • 108. Inclusion and Exclusion Criteria 883,969 continuously eligible patients with primary care for low back pain. Age <18 & >60 years (n=13,992) Low back pain claim in the past 6 months (n=38,955) Possible nonmusculoskeletal low back pain (n=154,729) Prior surgery for low back pain (n=148) 676,145 patients included in analysis
  • 109. Groups and Demographics Age (mean, sd) Gender (% female) Common Beneficiary Category Spouse/families Retired Other Active Duty Timing of PT Adherence All PT Users Adheren Patients Early Delayed Non‐Adher (n=158,2 t (n=676,14 (n=59,4 (n=98,8 ent (n=23,5 71) 16) 55) 5) (n=32,750) 50) 33.8 33.3 32.2 34.0 34.8 36.1 (11.2) (10.5) (10.4) (10.6) (11.3) (11.2) 39.10% 34.10% 32.80% 34.90% 41.80% 45.30% 19.80% 10.10% 12.80% 57.30% 14.50% 13.10% 15.30% 20.60% 7.30% 5.80% 8.10% 11.20% 8.80% 8.00% 9.30% 13.20% 69.50% 73.10% 67.20% 55.00% 22.80% 11.70% 14.90% 50.70%
  • 110. Additional Covariates Timing of PT All Patients PT Users Early Delayed (n=676,145 (n=158,271 (n=59,416 (n=98,855 ) ) ) ) Number of LBP diagnosis codes 1.5 1.4 1.4 1.4 (mean, sd) (1.8) 1.5) (1.2) (1.6) Number of prescription 13.6 15.2 12.9 16.5 medications (10.3) (10.8) (9.9) (11.0) (mean, sd) Co‐morbid mental health condition 0.082 0.084 0.078 0.088 Co‐morbid fibromyalgia diagnosis 0.019 0.017 0.016 0.018 Co‐morbid neck/thoracic spine 0.108 0.118 0.129 0.111 condition Narcotic use prior to index visit 34.10% 35.20% 34.10% 35.90% Hospitalization prior to index visit 7.20% 7.10% 6.90% 7.20% Total medical costs prior to index $3608.26 $3704.36 $3617.90 $3756.35 visit (8017.10) (7795.80) (8189.26) (7548.91) (mean, sd) Adherence Adherent Non‐Adhere (n=23,550 nt ) (n=32,750) 1.5 1.7 (1.7) (1.9) 15.9 (11.1) 16.4 (11.3) 0.09 0.02 0.088 0.023 0.116 0.142 37.50% 8.40% $4119.76 (10271.64 ) 38.40% 8.50% $4069.42 (7558.78)
  • 111. Adjusted Odds Ratios & 99% CIs Advanced Imaging E vs. D .47 (.45, .49) A vs. NA .68 (.64, .72) Lumbar surgery .52 (.47, .56) .80 (.71, .91) Spinal injection .47 (.45, .49) .78 (.73, .83) Opioid use .48 (.47, .50) .93 (.89, .98)
  • 112.
  • 113.
  • 114. Utilization of Services – Timing of Care Early Delayed Advanced imaging (MRI or CT) 12% 23% Lumbar spine surgery 3% 4% 8% 17% 59% 75% Lumbar spinal injections Opioid medication use
  • 115. Utilization of Services – Guideline Adherence Adherent Non-adherent Advanced imaging (MRI or CT) Lumbar spine surgery Lumbar spinal injections Opioid medication use 23% 30% 2% 4% 14% 18% 71% 73%
  • 116. Utilization of Services – Timing & Guideline Adherence E/A E/NA D/A D/NA Advanced imaging (MRI or CT) Lumbar spine surgery Lumbar spinal injections Opioid medication use 13% 20% 27% 35% 2% 3% 4% 5% 9% 13% 17% 21% 61% 64% 77% 78%
  • 117. Total Costs Incurred Over 2-year Follow-up $1,400 $1,200 $859 $1,000 $800 $733 $983 $600 $400 $200 $0 Prescription meds E/A E/NA L/A L/NA $1,145
  • 118. Total Costs Incurred Over 2-year Follow-up $16,000 $14,000 $12,000 $11,407 $13,030 $10,521 $10,000 $8,000 $6,000 $4,000 $2,000 $0 Inpatient E/A E/NA L/A L/NA $13,506
  • 119. Total Costs Incurred Over 2-year Follow-up $5,000 $4,340 $4,500 $3,670 $4,000 $3,500 $2,784 $3,000 $2,500 $2,110 $2,000 $1,500 $1,000 $500 $0 Total LBP E/A E/NA L/A L/NA
  • 120. Total Costs Incurred Over 2-year Follow-up $12,000 $10,000 $10,380 $8,470 $8,459 $8,000 $6,000 $4,000 $2,000 $0 Non LBP-related E/A E/NA L/A L/NA $10,589
  • 121. Low quality physical therapy delivered early is better than current standard of care for back pain management in the U.S.
  • 122. High quality physical therapy delivered early is even better
  • 123. Acknowledgements • This study is funded in part by the following organizations: • U.S. Air Force Medical Service Intramural Grant Program • Texas State University Faculty Grant
  • 124. References 1. mischvalente. back pain.; 2008. Available at: http://www.flickr.com/photos/mamibodega/2931602556/ [Accessed July 12, 2009]. 2. Martin BI, Deyo RA, Mirza SK, et al. Expenditures and health status among adults with back and neck problems. JAMA. 2008;299(6):656-664. 3. Groupman J. Annals of Medicine: A Knife in the Back: The New Yorker. 2002. Available at: http://www.newyorker.com/archive/2002/04/08/020408fa_FACT [Accessed July 13, 2009]. 4. Deyo RA, Nachemson A, Mirza SK. Spinal-fusion surgery - the case for restraint. N. Engl. J. Med. 2004;350(7):722-726. 5. Deyo R, Mirza S. The case for restraint in spinal surgery: does quality management have a role to play? Eur Spine J. 2009. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19266220 [Accessed July 14, 2009]. 6. Dave. stop back pain.; 2007. Available at: http://www.flickr.com/photos/funkypancake/1478208586/ [Accessed July 12, 2009]. 7. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J. 2008;8(1):8-20. 8. Chou R, Baisden J, Carragee EJ, et al. Surgery for low back pain: a review of the evidence for an American Pain Society Clinical Practice Guideline. Spine. 2009;34(10):1094-1109. 9. Chou R, Atlas SJ, Stanos SP, Rosenquist RW. Nonsurgical interventional therapies for low back pain: a review of the evidence for an american pain society clinical practice guideline. Spine. 2009;34(10):1078-1093. 10. Chou R, Fu R, Carrino JA, Deyo RA. Imaging strategies for low-back pain: systematic review and meta-analysis. Lancet. 2009;373(9662):463-472.

Notas del editor

  1. Low Back Pain: $86 billion/year (2005)• All arthritis: $80 billion (2003)• Cancer: $89 billion (2007)• Diabetes: $98 billion (2002)• Heart dis &amp; stroke: $258 billion (2005)• Costs for LBP rose 65% (inflationadjusted),1997-2005Martin BI, Deyo RA, et al. JAMA
  2. Low Back Pain: $86 billion/year (2005)• All arthritis: $80 billion (2003)• Cancer: $89 billion (2007)• Diabetes: $98 billion (2002)• Heart dis &amp; stroke: $258 billion (2005)• Costs for LBP rose 65% (inflationadjusted),1997-2005Martin BI, Deyo RA, et al. JAMA
  3. Low Back Pain: $86 billion/year (2005)• All arthritis: $80 billion (2003)• Cancer: $89 billion (2007)• Diabetes: $98 billion (2002)• Heart dis &amp; stroke: $258 billion (2005)• Costs for LBP rose 65% (inflationadjusted),1997-2005Martin BI, Deyo RA, et al. JAMA
  4. Low Back Pain: $86 billion/year (2005)• All arthritis: $80 billion (2003)• Cancer: $89 billion (2007)• Diabetes: $98 billion (2002)• Heart dis &amp; stroke: $258 billion (2005)• Costs for LBP rose 65% (inflationadjusted),1997-2005Martin BI, Deyo RA, et al. JAMA
  5. Low Back Pain: $86 billion/year (2005)• All arthritis: $80 billion (2003)• Cancer: $89 billion (2007)• Diabetes: $98 billion (2002)• Heart dis &amp; stroke: $258 billion (2005)• Costs for LBP rose 65% (inflationadjusted),1997-2005Martin BI, Deyo RA, et al. JAMA
  6. Tried to use colors to show “dose effect” across categories - ekr