1. Lazzaro Repetto UOC Oncologia Istituto Nazionale Ricovero e Cura Anziani Istituto di Ricovero e Cura a Carattere Scientifico, Roma Cancer in the older person 4th ESO-EONS Masterclass in Oncology Nursing 2-7 April 2011 Ermatingen (Lake Constance), Switzerland

2. Jemal et al, CA, ,2005, 55, 10

3. Assessing the Older Patient for Cancer Treatment 15% of all population 60% of all cases of cancer 70% of all death for cancer

5. As a guide, two ages are important milestones: 70 years because the prevalence of age-related changes strongly increases 85 years because the prevalence of frailty strongly increases There is No Short Definition of Elderly Cancer Patients Do these age limits fit requirements of onco-hematologist ?

7. Clinical approach to geriatric patient

10. Same Chronological Age; Different Functional Age Do we have clinical options available for both?

13. Geriatric assessment and detection of unexpected conditions

22. Balducci L, et al. Oncologist. 2000;5:224-237. Assessment Group 1 Life expectancy >Cancer Life-prolonging treatment Palliation Group 2 Group 3 <Cancer Treatment tolerance Yes No Comprehensive Geriatric Assessment (CGA) (frail elderly)

24. Commonly observed geriatric syndromes GER. SYNDROMES CLINICAL DESCRIPTION Delirium Delirium is a transient organic mental syndrome of acute onset, characterized by global impairment of cognitive functions, reduced level of consciousness, attention abnormalities, increased or decreased psychomotor activity and a disordered sleep-wake cycle. Falls A fall is a sudden, unintentional change in position causing an individual to land at a lower level, for example on an object, floor or ground, that is not consequence of a sudden onset of paralysis, epileptic seizure, or overwhelming external force. Frailty According to phenotypic definition, frailty is defined as the presence of > 3 of 5 components: muscle weakness and slow walking speed, exhaustion, low physical activity, and unintentional weight loss. The definition of frailty based on frailty index (FI) is based on deficit accumulation using 70 deficits from clinical examination . Dizziness Painless head discomfort with many causes including disturbances of vision, brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term used to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo . Urinary incontinence The inability to control urination or bladder control. The severity of urinary incontinence ranges from occasionally leaking urine to unpredictable episodes of strong urinary urgency. Syncope Partial or complete loss of consciousness with a temporary interruption of awareness of oneself and ones surroundings.

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