Chronic Kidney Disease - What You Need to Know

Chronic Kidney Disease What You Need to Know Phil Ramos, MD, MSCI Denver Nephrologists, P.C.

Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object]

The Kidney ,[object Object],[object Object],[object Object],[object Object]

The Nephron ,[object Object],[object Object],[object Object],[object Object]

Other Important Functions ,[object Object],[object Object],[object Object],[object Object]

Estimating Kidney Function ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

What is Chronic Kidney Disease ,[object Object],[object Object],[object Object],[object Object],National Kidney Foundation (NKF). Am J Kidney Dis. 2002;39(2 suppl 1):S1-S266.

CKD Progresses in Stages (Defined by eGFR) NKF. Am J Kidney Dis. 2002;39(2 suppl 1):S1-S266. CKD Stage Description GFR (mL/min/1.73 m 2 ) 1 Kidney damage with normal or  GFR  90 2 Kidney damage with mild  GFR 60-89 3 Moderate  GFR 30-59 4 Severe  GFR 15-29 5 Kidney failure <15 or dialysis

The Epidemic of CKD ,[object Object],[object Object],[object Object]

CKD Is a Growing Epidemic CKD Stage Number of Individuals* 1  90 3.6 million 2 60-89 6.5 million 3 30-59 15.5 million 4 15-29 700,000 5 <15 or dialysis 500,000 GFR (mL/min/1.73 m 2 ) *Coresh et al. JAMA; 298 (17): 2038 (2007) United States Renal Data System, 2008

Risk Factors for CKD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Medication Risk Factors: NSAID’s ,[object Object],[object Object],[object Object],[object Object],Gooch, K. et. al. Am J Med 2007;120.

NSAID’s ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Signs/Symptoms of CKD ,[object Object],[object Object],[object Object],[object Object],[object Object]

Signs/Symptoms of End Stage Renal Disease (ESRD) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Signs/Symptoms of End Stage Renal Disease (ESRD) ,[object Object],[object Object],[object Object]

Blood and Urine Results in CKD/ESRD ,[object Object],[object Object],[object Object],[object Object],[object Object]

Urinary Tract Obstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Kidney Cysts ,[object Object],[object Object]

Which Patients Should Be Screened for CKD? Levey et al. Ann Intern Med . 2003;139:137-147. USRDS. 1999 Annual Data Report. Available at: www.usrds.org. Susceptibility Risk Factors Progression Factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Primary Goals of Management in CKD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Primary Goals of Management in CKD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ESRD and Hemodialysis ,[object Object],[object Object],[object Object],[object Object]

ESRD and Peritoneal Dialysis ,[object Object],[object Object],[object Object],[object Object]

Renal Transplantation ,[object Object],[object Object],[object Object]

Prevention of CKD Most Important ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Chronic Kidney Disease - What You Need to Know

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