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Francisco Montes Campaña

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Najljepše džamije,katedrale,crkve i sinagoge

centar-obrazovanja

علم النفس اللونيColor psychology1

Marwa Merghani

Effect of acrylamide on testis of albino rats. ultrastructure and dna cytomet...

Prof. Hesham N. Mustafa

Effect of sodium selenite and vitamin e on the renal cortex in rats an ultras...

Prof. Hesham N. Mustafa

MORPHOLOGICAL STUDY OF THE MUSCLE- BONE INTERFACE IN MAN The aim of the present study was to investigate the histological structure of the fleshy muscle-bone interface in selected limb muscles in man, as compared to that of the enthesis, in an attempt to clarify the way muscle fibers transmit their contractile force to adjacent bone. The muscle specimens were taken from biceps and tendocalcaneus as examples for the tendon-bone attachment (enthesis), from external intercostal, brachioradialis, and external oblique muscles as examples for the linear fleshy attachment, and from infraspinatus and brachialis as examples for the fleshy attachment over a wide area. The muscle-bone interface specimens were collected form six formalin-fixed dissecting room elderly male cadavers with no gross pathology. The whole muscle-bone interface was extracted so that each specimen included the muscle and the underlying bone tissues. The specimens were fixed in 10% neutral buffered formol saline for one week, and then decalcified with 10% EDTA for about 4-6 weeks. Dehydrated in ascending grades of alcohols, cleared in xylol, and embedded in paraffin wax. Serial sections were cut at 8-µm thickness and stained with Haematoxylin and eosin, and Masson's trichrome. In the present work, it was found that tendon-bone attachment of either biceps brachii or tendocalcaneus was formed of four zones; zone 1 (Z1) of dense connective tissue, zone 2 (Z2) of fibrocartilage, zone 3 (Z3) of calcified fibrocartilage, and zone 4 (Z4) of compact bone. Serrated basophilic line "tidemark" was usually seen between fibrocartilage and calcified fibrocartilage zones. Moreover, differences in the distribution and population of chondrocytes occurred between zone 2 (Z2) and zone 3 (Z3). On the other hand, the muscle-bone interface of brachialis, infraspinatus, brachioradialis, and external intercostal muscles was noticed to be formed of three zones; zone 1 (Z1) of skeletal muscle tissue, zone 2 (Z2) of dense connective tissue, and zone 3 (Z3) of compact bone. The dense connective tissue zone interposed between the skeletal muscle fibers and the bone differed in its density and structure between the studied muscles. Moreover, some regions of the attachment site of the external oblique muscle were observed to include zones of fibrocartilage and calcified fibrocartilage so that a mixture of fibrocartilaginous and fibrous attachment could be identified. From the above mentioned findings it was concluded that three patterns of muscle-bone interfaces could be described according to the number and types of histological zones; (1) the classical pattern of tendon-bone interface (enthesis) formed of the four zones, (2) the fleshy pattern of the muscle-bone interface characterized by absence of fibrocartilage, (3) the third pattern is an admixture of the previous two patterns. The present findings would be helpful in clinical practice; especially, for the choice of the suitable muscle for transplant.

Morphological study of the musclebone interface in man 29.9.2004

Prof. Hesham N. Mustafa

Drama | Ajdin Smajlović

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Hardver Prezentacija

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Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. The aim of the current study is to investigate the possible beneficial effects of Hyphaene thebaica in DN. Materials and methods: For this, 50 male albino rats were divided into five groups: group I — represented the control group; group II — received Hyphaene thebaica extracts of 150 mg/kg BW by oral gavage for 6 weeks; group III — received single intraperitoneal injections of streptozotocin (50 mg/kg BW) to induce type-2 diabetes mellitus; group IV (protective) — diabetic rats received Hyphaene thebaica extract (150 mg/kg BW) orally for 6 weeks; group V (curative) — received Hyphaene thebaica extract (150 mg/kg BW) orally after the diagnosis of DN. Results: In the DN protected group, blood glucose, urea, and creatinine decreased significantly, while insulin and C-peptide increased significantly. Moreover, cystatin C and neutrophil gelatinase-associated lipocalin decreased. Collagen fibre deposition is increased with an apparent thickening of the parietal layer of Bowman’s capsules and the basal lamina of convoluted tubules, as well as increase of the immune-reaction of caspase-3 and desmin. The introduction of Hyphaene thebaica led to greater amelioration in the biochemical markers, apoptotic alterations, and podocyte injuries of the protected group than in the curative group. Conclusions: Hyphaene thebaica may be advised as a good choice that can delay diabetic renal complications. (Folia Morphol 2015; 74, 4: 447–457) Key words: diabetic nephropathy, Hyphaene thebaica, podocyte injury, apoptosis

The ameliorative potential of hyphaene thebaica on streptozotocin induced dia...

Prof. Hesham N. Mustafa

Destacado (8)

Najljepše džamije,katedrale,crkve i sinagoge

علم النفس اللونيColor psychology1

Effect of acrylamide on testis of albino rats. ultrastructure and dna cytomet...

Effect of sodium selenite and vitamin e on the renal cortex in rats an ultras...

Morphological study of the musclebone interface in man 29.9.2004

Drama | Ajdin Smajlović

Hardver Prezentacija

The ameliorative potential of hyphaene thebaica on streptozotocin induced dia...

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