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Relive: a game 
to learn how to save lives 
Dr Federico Semeraro 
Italian Resuscitation Council, Bologna Italy 
Luca Marchetti 
CEO Studio Evil, Bologna Italy
Dedicated to the Next Generation 
Andrea was born 20thNovember 2010 
20th November 2010 6.35 his first photo with iPhone 
2ndDecember 2010 First Skype Call Bologna-Porto 
21stNovember 2010 Andrea’s Secret Facebook Group 
23thNovember 2010 Andrea slept with music from iPod
2 full jumbo jets crashing with 
no survivors each and every day. 
Cardiac Arrest 
www.restartaheart.eu 
1,000 deaths per day every day of the year across Europe.
Bystanders CPR 
• Sweden 55% (Norderg et al. 2005) 
• Amsterdam 54% (Koster et al. 2001) 
• Seattle 52% (EMS Report 2012) 
• London 36.7% (London Ambul.Serv. NHS 2011) 
• US 32% (AHA 2012) 
• Bologna 11% (118 Bologna 2011) 
• Milano 11% (Morici et al. 2010) 
• Europe 11% (ERC 2013)
European Restart a Heart day
Mini-VREM project
Future of Health Award 2012
Future of Health Award 2012
Veel Dank
Motion detection technology as a tool for cardiopulmonary resuscitation (CPR) quality training: a randomised crossover mannequin pilot studyResuscitation 84 (April 2013) 501–507
Motion detection technology as a tool for cardiopulmonary resuscitation (CPR) quality training: a randomised crossover manikin pilot study 
Conclusions 
The Mini-VREM system was able to improve significantly the quality of chest compressions, 
in terms of compression rate and depth, 
performed by healthcare professionals and lay people 
in a simulated cardiac arrest scenario. 
The system was perceived as easy to use and providing an effective feedback.
Mini-VREM project 
present
Federico Semeraro: 
oSpecialty Doctor Anaesthesia and Intensive Care Maggiore Hospital Bologna, Italy. 
oItalian Resuscitation Council Executive Committee 
oRelive Project coordinator 
ErgaCerchiari: 
oClinical Director Anaesthesia and Intensive Care Maggiore Hospital Bologna, Italy. 
oPast-President Italian Resuscitation Council. 
oRelive Scientific Supervision 
“The doctors”
Antonio Frisoli: 
oAssociate Professor, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine coordinator & scientific supervisor 
Claudio Loconsole: 
oEng. PhD, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine developer 
“The Engineers”
Fabio Stroppa: 
oReserchFellow, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine developer 
Nicola Mastronicola: 
oResearch Fellow, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine developer 
“The Engineers”
Luca Marchetti: 
oStudio Evil CEO 
oRelive Game Development coordinator 
Marco Di Timoteo: 
oStudio Evil art director, lead designer 
oRelive Game Design 
“…and Game Dev”
Christian Meneghini: 
oStudio Evil CTO 
oRelive Game Technical Artist 
Luca Salmin: 
oStudio Evil Senior Developer 
oRelive Game Tools and Game play programmer 
“…Game Dev”
IRC Executive Committe
RELIVE 
RELIVE is a game about cardiopulmonary resuscitation. 
The main purpose of this game is to increase the awareness about this 
topic and push people, especially teenagers and young adults, to take 
a CPR class and be prepared to intervene in case of need. 
The idea is to create a fun and entertaining game, a SCI-FI opera, to 
gather the attention of the audience, and let the CPR concept slip 
through the game.
During the game the player is forced to learn the basis of CPR to move 
forward in the story, in an interesting and non-invasive way. 
To keep the CPR skills razor sharp and for a fun and fast CPR 
challenge a tournament mode will encourage group play. 
Family, schools and groups will challenge themselves to beat the best 
score. 
RELIVE
RELIVE 
TOURNAMENT MODE 
to increase CPR 
skill and knowledge 
STORY MODE 
to increase cardiac 
arrest awareness
•Standard setup (PC Keyboard & Mouse) 
•Tournamentmode setup 
–Full trackingsetup 1 –Microsoft Kinect 
–Full trackingsetup 2 –Intel PerceptualCamera (2015) 
–OculusRift(2015) 
RELIVE
Relive Study 
•Baseline CPR knowledge and skill of target groups(March 2014) 
collecting data from a selected target group as a baseline knowledge (MCQ) and CPR skills (CPR quality data): 
–MCQ about cardiac arrest, CPR and algorithm BLS & AED; 
–2 minute CPR without any previous training (quality data collected with Relive) 
•Game Phase -Target group play with RELIVE game (May 2014) 
–Target groups played with RELIVE in the competition modedirectly at school; the mission of the target groups was to participate to a 2-minute CPR competition. 
–Only one session of 2-minute CPR competition
Relive Study 
•Retention collecting data from the same target groups about CPR skills (CPR quality data) and knowledge (MCQ) (Sept 2014): 
–MCQ about cardiac arrest, CPR and algorithm BLS & AED 
–2 minute CPR (quality data collected with Relive). 
Baseline 
March 
Competition 
May 
Retention 
Sept 
B/C 
B/R
Relive Study B/C 
•Baseline (based on 65 students): 
–Mean compression rate (cpm): 92±34 
–Mean compression depth (mm): 29±12 
•Competition (based on 65 students): 
–Mean compression rate (cpm): 111±10 
–Mean compression depth (mm): 46±8 
•ERC GL: rate 100-120 cpm& depth 50-60 mm 
•t student baseline vs competition 
–Mean compression rate p < 0.0001 
–Mean compression depth p < 0.0001
Relive Study B/R 
•Baseline (based on 52 students): 
–Mean compression rate (cpm): 97±35 
–Mean compression depth (mm): 30±11 
•Retention (based on 52 students) 
–Mean compression rate (cpm): 133±39 
–Mean compression depth (mm): 47±15 
•ERC GL: rate 100-120 cpm& depth 50-60 mm 
•t student baseline vs retention 
–Mean compression rate p < 0.0001 
–Mean compression depth p < 0.0001
RELIVE 
RELIVE TOURNAMENT MODEEVALUATION
Relive Study 
Q1 It was difficult to use Relive in the competition mode 
1 -Stronglydisagree 
2 -Disagree 
3 -Somewhatdisagree 
4 -Neitheragreeor disagree 
5 -Somewhatagree 
6-Agree 
7 -Stronglyagree 
Medianresponse(65): 3 Somewhatdisagree 
Q2 
The feedback thatyoureceivedfrom Relive game on yourchestcompressionsperformance during2 minutes of CPR wereclear 
Medianresponse(65): 6 Agree
Relive Study 
Q3 Relive helped you to perform a chest compression rate between 100 and 120 compressions per minute as recommended by 2010 guidelines 
1 -Stronglydisagree 
2 -Disagree 
3 -Somewhatdisagree 
4 -Neitheragreeor disagree 
5 -Somewhatagree 
6-Agree 
7 -Stronglyagree 
Medianresponse(65): 6 Agree 
Q4 
Relive helped you to perform a chest compression depth between 50 and 60 millimetersas 
recommended by 2010 guidelines 
Medianresponse(65): 6 Agree
Relive Study 
Relivegame competitionevaluation(2 ItalianSchools) 
65 students 
Q1 
Q2 
Q3 
Q4 
3 
6 
6 
6
Relive Study 
Relivegame competitionevaluation(Public PlaceEventBologna) 
33 students 
Q1 
Q2 
Q3 
Q4 
3 
6 
6 
6
Relive Study 
Relivegame competitionevaluation(IRC CongressNaples) 
34 HPs 
Q1 
Q2 
Q3 
Q4 
3 
6 
6 
6
Testing & Outcome 
Primary outcome: 
•increase awareness about cardiac arrest and CPRin TG 
•> 70% in TG 
Secondary outcome: 
•a significant improvement of CPR knowledge in TG 
•> 50% in TG 
•a significant improvement of CPR skills in TG 
•Improve significantly CPR skill quality data pre-post 
-chest compression rate and depth baseline (pre) vspost (feedback) 
The game will accomplish the compliance objective if the primary 
outcome and at least one of the secondary outcome are reached. 
TGTarget Group
Relive Study 
Secondary outcome: 
•a significant improvement of CPR knowledge in TG 
> 50% in TG 
MCQ (10 questions) –52 students 
Baseline 46±13 vs Retention 62±13 p ≤ 0.01 
Students 38/52 (improvement in 73%of target group) 
•a significant improvement of CPR skills in TG 
Improve significantly CPR skill quality data pre-post 
-chest compression rate and depth baseline (pre) vs retention (post)
Relive Study B/R 
•Baseline (based on 52 students): 
–Mean compression rate (cpm): 97±35 
–Mean compression depth (mm): 30±11 
•Retention (based on 52 students) 
–Mean compression rate (cpm): 133±39 
–Mean compression depth (mm): 47±15 
•t student baseline vs retention 
–Mean compression rate p < 0.0001 
–Mean compression depth p < 0.0001 
–Students 38/52 (improvement in 73%of target group)
Testing & Outcome 
Primary outcome: 
•increase awareness about cardiac arrest and CPRin TG 
> 70% in TG 
CPR Knowledge improvement in 73% of target group 
CPR Skill improvement in 73% of target group 
The game will accomplish the compliance objective if the primary 
outcome and at least one of the secondary outcome are reached.
•ReliveInternational launch 
•ReliveNetherlands Study 
•ERC collaborationin severalcountries 
•EuropeanRestartHeartDay2015 
The Future
relivegame.com

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Games for Health Europe - Federico Semeraro & Luca Marchetti - Relive: a game to learn how to save lives

  • 1. Relive: a game to learn how to save lives Dr Federico Semeraro Italian Resuscitation Council, Bologna Italy Luca Marchetti CEO Studio Evil, Bologna Italy
  • 2. Dedicated to the Next Generation Andrea was born 20thNovember 2010 20th November 2010 6.35 his first photo with iPhone 2ndDecember 2010 First Skype Call Bologna-Porto 21stNovember 2010 Andrea’s Secret Facebook Group 23thNovember 2010 Andrea slept with music from iPod
  • 3.
  • 4. 2 full jumbo jets crashing with no survivors each and every day. Cardiac Arrest www.restartaheart.eu 1,000 deaths per day every day of the year across Europe.
  • 5. Bystanders CPR • Sweden 55% (Norderg et al. 2005) • Amsterdam 54% (Koster et al. 2001) • Seattle 52% (EMS Report 2012) • London 36.7% (London Ambul.Serv. NHS 2011) • US 32% (AHA 2012) • Bologna 11% (118 Bologna 2011) • Milano 11% (Morici et al. 2010) • Europe 11% (ERC 2013)
  • 6. European Restart a Heart day
  • 7.
  • 9. Future of Health Award 2012
  • 10. Future of Health Award 2012
  • 12.
  • 13. Motion detection technology as a tool for cardiopulmonary resuscitation (CPR) quality training: a randomised crossover mannequin pilot studyResuscitation 84 (April 2013) 501–507
  • 14. Motion detection technology as a tool for cardiopulmonary resuscitation (CPR) quality training: a randomised crossover manikin pilot study Conclusions The Mini-VREM system was able to improve significantly the quality of chest compressions, in terms of compression rate and depth, performed by healthcare professionals and lay people in a simulated cardiac arrest scenario. The system was perceived as easy to use and providing an effective feedback.
  • 16. Federico Semeraro: oSpecialty Doctor Anaesthesia and Intensive Care Maggiore Hospital Bologna, Italy. oItalian Resuscitation Council Executive Committee oRelive Project coordinator ErgaCerchiari: oClinical Director Anaesthesia and Intensive Care Maggiore Hospital Bologna, Italy. oPast-President Italian Resuscitation Council. oRelive Scientific Supervision “The doctors”
  • 17. Antonio Frisoli: oAssociate Professor, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine coordinator & scientific supervisor Claudio Loconsole: oEng. PhD, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine developer “The Engineers”
  • 18. Fabio Stroppa: oReserchFellow, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine developer Nicola Mastronicola: oResearch Fellow, PERCRO Laboratory, ScuolaSuperioreSant'AnnaPisa, Italy. Relive Tracking engine developer “The Engineers”
  • 19. Luca Marchetti: oStudio Evil CEO oRelive Game Development coordinator Marco Di Timoteo: oStudio Evil art director, lead designer oRelive Game Design “…and Game Dev”
  • 20. Christian Meneghini: oStudio Evil CTO oRelive Game Technical Artist Luca Salmin: oStudio Evil Senior Developer oRelive Game Tools and Game play programmer “…Game Dev”
  • 22. RELIVE RELIVE is a game about cardiopulmonary resuscitation. The main purpose of this game is to increase the awareness about this topic and push people, especially teenagers and young adults, to take a CPR class and be prepared to intervene in case of need. The idea is to create a fun and entertaining game, a SCI-FI opera, to gather the attention of the audience, and let the CPR concept slip through the game.
  • 23. During the game the player is forced to learn the basis of CPR to move forward in the story, in an interesting and non-invasive way. To keep the CPR skills razor sharp and for a fun and fast CPR challenge a tournament mode will encourage group play. Family, schools and groups will challenge themselves to beat the best score. RELIVE
  • 24. RELIVE TOURNAMENT MODE to increase CPR skill and knowledge STORY MODE to increase cardiac arrest awareness
  • 25. •Standard setup (PC Keyboard & Mouse) •Tournamentmode setup –Full trackingsetup 1 –Microsoft Kinect –Full trackingsetup 2 –Intel PerceptualCamera (2015) –OculusRift(2015) RELIVE
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31. Relive Study •Baseline CPR knowledge and skill of target groups(March 2014) collecting data from a selected target group as a baseline knowledge (MCQ) and CPR skills (CPR quality data): –MCQ about cardiac arrest, CPR and algorithm BLS & AED; –2 minute CPR without any previous training (quality data collected with Relive) •Game Phase -Target group play with RELIVE game (May 2014) –Target groups played with RELIVE in the competition modedirectly at school; the mission of the target groups was to participate to a 2-minute CPR competition. –Only one session of 2-minute CPR competition
  • 32. Relive Study •Retention collecting data from the same target groups about CPR skills (CPR quality data) and knowledge (MCQ) (Sept 2014): –MCQ about cardiac arrest, CPR and algorithm BLS & AED –2 minute CPR (quality data collected with Relive). Baseline March Competition May Retention Sept B/C B/R
  • 33. Relive Study B/C •Baseline (based on 65 students): –Mean compression rate (cpm): 92±34 –Mean compression depth (mm): 29±12 •Competition (based on 65 students): –Mean compression rate (cpm): 111±10 –Mean compression depth (mm): 46±8 •ERC GL: rate 100-120 cpm& depth 50-60 mm •t student baseline vs competition –Mean compression rate p < 0.0001 –Mean compression depth p < 0.0001
  • 34. Relive Study B/R •Baseline (based on 52 students): –Mean compression rate (cpm): 97±35 –Mean compression depth (mm): 30±11 •Retention (based on 52 students) –Mean compression rate (cpm): 133±39 –Mean compression depth (mm): 47±15 •ERC GL: rate 100-120 cpm& depth 50-60 mm •t student baseline vs retention –Mean compression rate p < 0.0001 –Mean compression depth p < 0.0001
  • 35. RELIVE RELIVE TOURNAMENT MODEEVALUATION
  • 36. Relive Study Q1 It was difficult to use Relive in the competition mode 1 -Stronglydisagree 2 -Disagree 3 -Somewhatdisagree 4 -Neitheragreeor disagree 5 -Somewhatagree 6-Agree 7 -Stronglyagree Medianresponse(65): 3 Somewhatdisagree Q2 The feedback thatyoureceivedfrom Relive game on yourchestcompressionsperformance during2 minutes of CPR wereclear Medianresponse(65): 6 Agree
  • 37. Relive Study Q3 Relive helped you to perform a chest compression rate between 100 and 120 compressions per minute as recommended by 2010 guidelines 1 -Stronglydisagree 2 -Disagree 3 -Somewhatdisagree 4 -Neitheragreeor disagree 5 -Somewhatagree 6-Agree 7 -Stronglyagree Medianresponse(65): 6 Agree Q4 Relive helped you to perform a chest compression depth between 50 and 60 millimetersas recommended by 2010 guidelines Medianresponse(65): 6 Agree
  • 38. Relive Study Relivegame competitionevaluation(2 ItalianSchools) 65 students Q1 Q2 Q3 Q4 3 6 6 6
  • 39. Relive Study Relivegame competitionevaluation(Public PlaceEventBologna) 33 students Q1 Q2 Q3 Q4 3 6 6 6
  • 40. Relive Study Relivegame competitionevaluation(IRC CongressNaples) 34 HPs Q1 Q2 Q3 Q4 3 6 6 6
  • 41. Testing & Outcome Primary outcome: •increase awareness about cardiac arrest and CPRin TG •> 70% in TG Secondary outcome: •a significant improvement of CPR knowledge in TG •> 50% in TG •a significant improvement of CPR skills in TG •Improve significantly CPR skill quality data pre-post -chest compression rate and depth baseline (pre) vspost (feedback) The game will accomplish the compliance objective if the primary outcome and at least one of the secondary outcome are reached. TGTarget Group
  • 42. Relive Study Secondary outcome: •a significant improvement of CPR knowledge in TG > 50% in TG MCQ (10 questions) –52 students Baseline 46±13 vs Retention 62±13 p ≤ 0.01 Students 38/52 (improvement in 73%of target group) •a significant improvement of CPR skills in TG Improve significantly CPR skill quality data pre-post -chest compression rate and depth baseline (pre) vs retention (post)
  • 43. Relive Study B/R •Baseline (based on 52 students): –Mean compression rate (cpm): 97±35 –Mean compression depth (mm): 30±11 •Retention (based on 52 students) –Mean compression rate (cpm): 133±39 –Mean compression depth (mm): 47±15 •t student baseline vs retention –Mean compression rate p < 0.0001 –Mean compression depth p < 0.0001 –Students 38/52 (improvement in 73%of target group)
  • 44. Testing & Outcome Primary outcome: •increase awareness about cardiac arrest and CPRin TG > 70% in TG CPR Knowledge improvement in 73% of target group CPR Skill improvement in 73% of target group The game will accomplish the compliance objective if the primary outcome and at least one of the secondary outcome are reached.
  • 45. •ReliveInternational launch •ReliveNetherlands Study •ERC collaborationin severalcountries •EuropeanRestartHeartDay2015 The Future