This presentation includes case study of a person affected with Swine Flu.

1. CASE PRESENTATION
SWINE FLU(H1 N1 FLU)
Presented By-
Mr. Gaurav Shriram Patil
Final Year B. Pharm
KVPS, Institute of Pharmaceutical Education, Boradi.
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2. SWINE FLU (H1 N1 FLU)
Technically the term Swine flu refers to Influenza in Pigs. Occasionally. Pigs
transmit influenza viruses to people, mainly hog farmers and veterinarians.
The human respiratory infection caused by a particular influenza virus H1 N1
strain- Popularly known as Swine Flu. It was recognized first in 2009. Afterward
the cases were reported worldwide as a result, the world health organization
(WHO) declared the infection a global pandemic.
The pandemic was declared over in august 2010. Currently the H1 N1 still
circulating in humans as a seasonal flu virus and is included in the seasonal flu
vaccine .
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3. SYMPTOMS
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4. SYMPTOMS
 Swine Flu symptoms develop about one to three days after you’re exposed to
the virus and continue about seven days.
When to see a doctor: Its not a necessary to see a doctor if you’re generally
healthy and develop flu sings and symptoms, such as fever , cough and body
aches. Call your doctor, however you have flu like symptoms and if you have
chronic diseases.
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5. CAUSES & RISK FACTORS
 CAUSES:
Influenza viruses infect the cells lining of your nose , throat and lungs. The
virus enters your body when you inhale contaminant droplets or transfer live
virus from contaminated surface to your eyes , nose and mouth.
You cant catch a Swine flu from eating pork.
RISK FACTORS:
Swine farmers and veterinarians have the highest risk of true swine flu because
of the exposure to pigs.
Also if you’ve travelled to area where many people are affected by Swine Flu.
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6. PROFORMA
1. Name: Dinkar Bhoi
2. Age : 60 Years
3. Sex : Male
4. Address : Manjrod , Shirpur.
5. Weight: 74 Kg
6. Hospital Name : Radha Hospital.
7. DOA : 18.08.2019
8. DOD : 25.08.2019
9. Physician Name : Dr. Pitamber Nilkanth Dighore.
10. Patients Occupation : Farmer.
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7. PROFORMA
11. Social History : Alcoholic , Non smoker , Non Vegetarian.
12. Body Temp : 102.08 F.
13. Blood Pressure : 116/92 mm/hg.
14. Pulse : 102/ min
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8. HAEMOGRAM
INVESTIGATION RESULT NORMAL RANGE
Hemoglobin 13.6 mg/dl 12-16 mg/dl
RBC Count 4.22 mil/cmm 3.8-5.8 mil/cmm
WBC Count 9000 /mm3 5000-11000/mm3
Platelet Count 2.26 lakh/mm3 1.4-4.4 lakh/mm
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9. HAEMOGRAM
Differential Count
INVSTIGATION RESULT NORMAL RANGE
Neutrophils 88% 40-70%
Lymphocytes 05% 20-45%
Eosinophil 03% 0-6%
Monocytes 05% 0-8%
Basophils 0% 0-1%
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10. OTHER TEST
The general diagnosis of Swine flu is done on the basis of severity of symptoms
and the following were confirmatory tests
Confirmation of the diagnosis:
TEST DESCRIPTION
Routine blood tests Haemogram Profile is studied.
Chest X- ray Use to check other
complication like pneumonia.
Nose or Throat Swab It gives result in just 15 min.
Kit to Diagnose flu Develop by CDC. Gives results
in 4 hours
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11. TREATMENTS AND DRUGS
SR.
NO.
Medications API Dose Time Frequency Route Category
1 C. Tamiflu Oseltamivir
acid
500mg Twice a day 24 hours Oral Antiviral
2 T. Pan 40 Pantoprazole 40mg Once a day 12 hours Oral Antacid
3 Relenza - - Twice a day 12 hours Inhalation,
IV
Antiviral
4 T. Clavam
625
Amoxicillin
and
clavulanic
acid
500mg+125
mg
Twice a day 12 hours Oral Antibiotics
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12. MODE OFACTION OF DRUGS
Mode of action of TAMIFLU:
Oseltamivir inhibits the neuraminidase enzyme, which is expressed on the viral surface. The
enzyme promotes release of virus from infected cells and facilitates viral movement within the
respiratory tract.
Mode of action of Relenza:
Zanamivir works by binding to the active site of neuraminidase protein, rendering the influenza
virus unable to escape its host cell and others. It also inhibitor of influenza virus in vitro and in
vivo.
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13. MODE OFACTION OF DRUGS
Mode of action of Clavam:
Amoxicillin binds to penicillin binding proteins within the bacterial cell wall and inhibits
bacterial cell wall synthesis. Clavulanic acid is beta lactam, structurally related to penicillin, that
may inactivate certain beta lactamase enzymes.
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14. SIDE EFFECTS
oSide Effects of Influenza Vaccines and Drugs:
oWheezing
oHypersensitivity reactions
oLethargy
o Sore Throat
oHeadache.
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15. LIFE STYLE AND HOME
REMEDIES
There are certain measures also helps to prevent Swine Flu (H1 N1) and limit
the spread:
 Stay home if you’re sick: If you do have swine flu, you can give it to others starting about 24
hours before you develop symptoms and ending about seven days later.
Wash your hands thoroughly and frequently: Use soap and water or if they are unavailable
use alcohol base sanitizer.
Contain your cough and sneezes: Cover your mouth and nose when you sneeze or cough. To
avoid contaminating yours hands and other body parts too.
Avoid contact : Stay away from crowds if possible. And if you’re at risk of complications fro
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16. REFERNCES
1. Review of the Pharmacology by the Gobind Rai Garg and Sparsh Gupta, Ninth edition ,
Jaypee Brothers Medical Publishers, New Delhi.
2. K.D.Tripathi Essentials of Medical Pharmacology.
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17. AT LAST
THANK YOU!
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