1. CHAPTER 10: IMMUNITY EDWARD JENNER The Influenza Epidemic of 1918 – 1919 killed 22 million people in 18 months

11. These cells extend long pseudopodia that can attach to polysaccharides on a microbe’s surface, engulfing the microbes by phagocytosis, and fusing the resulting vacuole with a lysosome

27. A single antigen such as a bacterial surface protein usually has several effective epitopes, each capable of inducing the production of specific antibody

44. Structure of the lymph node

45. Structure of the spleen

68. Summary of Antibody-antigen Interaction

69. 10.2 Development of Immunity

74. Antigen molecules bind to the antigen receptors of only one of the six B cells shown The selected B cell proliferates to give rise to a clone of identical cells bearing receptors for the selecting antigen Some proliferating cells develop into long-lived memory cells that can respond rapidly upon subsequent exposure to the same antigen Some proliferating cells develop into short-lived plasma cells that secrete antibody specific for the antigen

93. Fig. 57.9

94. IMMUNE RESPONSES

108. Cytotoxic T cell

117. The immune system’s capacity to distinguish self from nonself limits blood transfusion and tissue transplantation

124. 10.3 Immune Disorder: SLE and AIDS

140. Rheumatoid Arthritis of the Hands Rheumatoid arthritis can result in severe deformation of the hands, wrists, feet, ankles, hips, and shoulders. The characteristic swelling, pain, and restricted movement Rheumatoid arthritis can result in severe deformation of the hands, wrists, feet, ankles, hips and shoulders. The characteristic swelling, pain and restricted movement

142. Myasthenia gravis Myasthenia gravis is a neuromuscular disease that causes weakness and fatigue, most commonly in the muscles of the eyes, face, throat and limbs. MG is an acquired disease, meaning it isn't inherited as a genetic disease. The word "myasthenia" means muscle weakness.

143. Systemic lupus erythematosus

145. A I D S C QUIRED MMUNO - EFICIENCY YNDROME

146. INTRODUCTION

153. Causative Agent RNA Capsid RNA Reverse transcriptase enzyme Viral envelope Glycoprotein

155. The Causes

157. The Symptoms

161. The Symptoms Kaposi’s sarcoma a cancer of the skin and blood vessels (purplish spot on skin)

162. The mechanism of infection and HIV replication

174. 1 2 3 4 5 6 7 8

175. The new HIV particles leaving the host’s cell Mature form Budding particle

180. HIV on a lymphocyte HIV particles