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Linee guida e timing chirurgico dell’Insufficienza Aortica :  che cosa attende migliore definizione Dr. Antonio Federico  “ L’Insufficienza Valvolare Aortica” Villa Maria Cecilia Hospital 15 – 16 Maggio 2009
 
Natural History of Aortic Regurgitation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ACC/AHA VHD Guidelines: 2008 Focused Update Incorporated  JACC Vol. 52, No. 13, 2008 e1–142
Indici di performance ventricolare sinistra + + + +  + +  + +  + + +  S.F. (v.n. 25%-45%) + + + +  + + + + +  0 +  Dimens. sistoliche + + +  + +  + + +  0  + + +  VCF (SF/ET) (v.n.>1,1circ./sc) + +  + +  + +  + +  + + + +  dP/dt + + + +  + + + + + + + + F.E. fattibilità Dipendenza Massa/vol. Dipendenza da postcarico Dipendenza da precarico Sensibilità a inotropismo
Indici di performance ventricolare sinistra ,[object Object],[object Object]
[object Object],Am. J. Cardiol. 2003;92:755-758
Diagnostic and prognostic value of N-terminal pro B-type natriuretic peptide in patients with chronic aortic regurgitation   ,[object Object],[object Object],[object Object],[object Object],[object Object],International Journal of Cardiology 2008 Vol. 127 (3): 321-327
BNP e timing CCH nella SVA severa JACC 2006 (47), 11:2141 - 2151
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
EF 54 % EF 51 % Rest Exercise Sv 5.4 cm/s Sv 6.1 cm/s Delay 60 ms F UP:Acute HF EF 34% Sv 2.4 cm/s “ Stress testing could be useful for the early detection of  latent systolic failure”
Proposta flow chart per timing chirurgico in I. Ao DTD 55-70 mm  +  DTS 45/55 mm  DTD > 70 mm  +  DTS > 55 mm F.E. > 55%  F.E. < 55% dP/dt  +  BNP =  < > +  stress ECO =  <  Follow up   CCH
Quale ruolo per la terapia medica ?
Quale ruolo per la terapia medica ? JACC 2005;45:1205-30
Quale ruolo per la terapia medica ? ,[object Object],[object Object],[object Object],JACC 2005;45:1205-30
Quale ruolo per la terapia medica ? ,[object Object],[object Object],[object Object],N Engl J Med 2005;353:1342-9 .
[object Object],Circulation 2004;110:1477 - 1483
Quale ruolo per la terapia medica ? ,[object Object],[object Object],[object Object],[object Object],J. Am. Coll. Cardiol.  2008;52;e1-e142
Quale ruolo per la terapia medica ? ,[object Object],[object Object],JACC   2008;52;e1-e142
Quando intervenire su I. Ao. associata ad altra valvulopatia ? ,[object Object],JACC 2005;45:1205-30
Insufficienza aortica + stenosi mitralica severa ,[object Object],[object Object],[object Object],[object Object],[object Object],JACC 2005;45:1205-30
Insufficienza aortica + insufficienza mitralica severe ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Quando operare una I. Ao. moderata ,[object Object],[object Object],[object Object],[object Object],[object Object],European Heart Journal (2007) 28, 230–268 1. AVR may be considered in patients with moderate AR while undergoing surgery on the ascending aorta.  (IIb evidence: C) 2. AVR may be considered in patients with moderate AR while undergoing CABG.  (II b evidence: C) JACC 2005;45:1205-30
La riparabilità della valvola modifica il timing chirurgico ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ACC/AHA VHD Guidelines: 2008 Focused Update Incorporated  JACC Vol. 52, No. 13, 2008 e1–142
CONCLUSIONI ,[object Object],[object Object],[object Object],[object Object]
CONCLUSIONI ,[object Object],[object Object],[object Object],[object Object]
CONCLUSIONI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CONCLUSIONI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Linee guida e timing chirurgico insufficienza aortica

  • 1. Linee guida e timing chirurgico dell’Insufficienza Aortica : che cosa attende migliore definizione Dr. Antonio Federico “ L’Insufficienza Valvolare Aortica” Villa Maria Cecilia Hospital 15 – 16 Maggio 2009
  • 2.  
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  • 4. Indici di performance ventricolare sinistra + + + + + + + + + + + S.F. (v.n. 25%-45%) + + + + + + + + + 0 + Dimens. sistoliche + + + + + + + + 0 + + + VCF (SF/ET) (v.n.>1,1circ./sc) + + + + + + + + + + + + dP/dt + + + + + + + + + + + + F.E. fattibilità Dipendenza Massa/vol. Dipendenza da postcarico Dipendenza da precarico Sensibilità a inotropismo
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  • 8. BNP e timing CCH nella SVA severa JACC 2006 (47), 11:2141 - 2151
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  • 11. EF 54 % EF 51 % Rest Exercise Sv 5.4 cm/s Sv 6.1 cm/s Delay 60 ms F UP:Acute HF EF 34% Sv 2.4 cm/s “ Stress testing could be useful for the early detection of latent systolic failure”
  • 12. Proposta flow chart per timing chirurgico in I. Ao DTD 55-70 mm + DTS 45/55 mm DTD > 70 mm + DTS > 55 mm F.E. > 55% F.E. < 55% dP/dt + BNP = < > + stress ECO = < Follow up CCH
  • 13. Quale ruolo per la terapia medica ?
  • 14. Quale ruolo per la terapia medica ? JACC 2005;45:1205-30
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