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Specific Defense (pg 8)
Specific Defense (pg 8)
• Third line of defense
• Results in immunity
Specific Defense (pg 8)
• Third line of defense
• Results in immunity
Characteristics:
1. Specific: recognizes and acts against
particular pathogens
Specific Defense (pg 8)
• Third line of defense
• Results in immunity
Characteristics:
1. Specific: recognizes and acts against
particular pathogens
2. Systemic: immunity is not restricted to the
initial infection site
Specific Defense (pg 8)
• Third line of defense
• Results in immunity
• Characteristics:
1. Specific: recognizes and acts against
particular pathogens
2. Systemic: immunity is not restricted to the
initial infection site
3. Memory: Mounts an even stronger attack on
pathogens that have been previously
encountered
Definitions
• Antigen: molecules that are recognized as
foreign by the body. Bacteria and other
pathogens bear such foreign molecules on
the surface of their cells.
Definitions
• Antigen: molecules that are recognized as
foreign by the body. Bacteria and other
pathogens bear such foreign molecules on
the surface of their cells.
• Antibody: Y-shaped proteins produced by
the body. Each antibody attacks only one
particular antigen and disables it. “Predator
drones”
Types of Lymphocytes
• All lymphocytes are made in the bone
marrow, but they go to different places to
become immunocompetent (capable of
responding to a specific antigen)
Types of Lymphocytes
• All lymphocytes are made in the bone
marrow, but they go to different places to
become immunocompetent (capable of
responding to a specific antigen)
• T-lymphocytes (70%): mature in the thymus.
Involved in cell-mediated immunity, where t-
lymphocytes directly attack antigens. Most
effective against virus-infected cells, cancer
cells, foreign tissue, fungi, protozoans
Types of Lymphocytes
• T-lymphocytes (70%): mature in the thymus.
Involved in cell-mediated immunity, where t-
lymphocytes directly attack antigens. Most
effective against virus-infected cells, cancer
cells, foreign tissue, fungi, protozoans
• B-lymphocytes (30%): mature in the bone
marrow. Involved in antibody-mediated
immunity. B-lymphocytes don’t attack
directly, but produce antibodies that bind to
the antigen and inactivate it. Most effective
against bacteria, viruses outside of cells, and
toxins
Output (pg 9)
• Paste in Antibody-mediated and Cell-mediated
immunity diagrams
Acquired Immunity (pg 10)
Acquired Immunity (pg 10)
• Active: Individual’s own body produces
memory T-cells and B-cells
Acquired Immunity (pg 10)
• Active: Individual’s own body produces
memory T-cells and B-cells
• Passive: Immune agents are made in someone
else’s body and then transferred to the
individual
Acquired Immunity (pg 10)
1. Active natural: Contract a disease and
produce memory cells
Acquired Immunity (pg 10)
1. Active natural: Contract a disease and
produce memory cells
2. Active artificial: receive a vaccination and
produce memory cells
Acquired Immunity (pg 10)
1. Active natural: Contract a disease and
produce memory cells
2. Active artificial: receive a vaccination and
produce memory cells
3. Passive natural: baby receive maternal
antibodies through placenta or breast milk
Acquired Immunity (pg 10)
1. Active natural: Contract a disease and
produce memory cells
2. Active artificial: receive a vaccination and
produce memory cells
3. Passive natural: baby receive maternal
antibodies through placenta or breast milk
4. Passive artificial: receive antiserum that
contains antibodies produced in another
host. Used to treat rabies, botulism, bites
from venomous snakes and spiders

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Specific defense

  • 2. Specific Defense (pg 8) • Third line of defense • Results in immunity
  • 3. Specific Defense (pg 8) • Third line of defense • Results in immunity Characteristics: 1. Specific: recognizes and acts against particular pathogens
  • 4. Specific Defense (pg 8) • Third line of defense • Results in immunity Characteristics: 1. Specific: recognizes and acts against particular pathogens 2. Systemic: immunity is not restricted to the initial infection site
  • 5. Specific Defense (pg 8) • Third line of defense • Results in immunity • Characteristics: 1. Specific: recognizes and acts against particular pathogens 2. Systemic: immunity is not restricted to the initial infection site 3. Memory: Mounts an even stronger attack on pathogens that have been previously encountered
  • 6. Definitions • Antigen: molecules that are recognized as foreign by the body. Bacteria and other pathogens bear such foreign molecules on the surface of their cells.
  • 7. Definitions • Antigen: molecules that are recognized as foreign by the body. Bacteria and other pathogens bear such foreign molecules on the surface of their cells. • Antibody: Y-shaped proteins produced by the body. Each antibody attacks only one particular antigen and disables it. “Predator drones”
  • 8. Types of Lymphocytes • All lymphocytes are made in the bone marrow, but they go to different places to become immunocompetent (capable of responding to a specific antigen)
  • 9. Types of Lymphocytes • All lymphocytes are made in the bone marrow, but they go to different places to become immunocompetent (capable of responding to a specific antigen) • T-lymphocytes (70%): mature in the thymus. Involved in cell-mediated immunity, where t- lymphocytes directly attack antigens. Most effective against virus-infected cells, cancer cells, foreign tissue, fungi, protozoans
  • 10. Types of Lymphocytes • T-lymphocytes (70%): mature in the thymus. Involved in cell-mediated immunity, where t- lymphocytes directly attack antigens. Most effective against virus-infected cells, cancer cells, foreign tissue, fungi, protozoans • B-lymphocytes (30%): mature in the bone marrow. Involved in antibody-mediated immunity. B-lymphocytes don’t attack directly, but produce antibodies that bind to the antigen and inactivate it. Most effective against bacteria, viruses outside of cells, and toxins
  • 11. Output (pg 9) • Paste in Antibody-mediated and Cell-mediated immunity diagrams
  • 13. Acquired Immunity (pg 10) • Active: Individual’s own body produces memory T-cells and B-cells
  • 14. Acquired Immunity (pg 10) • Active: Individual’s own body produces memory T-cells and B-cells • Passive: Immune agents are made in someone else’s body and then transferred to the individual
  • 15. Acquired Immunity (pg 10) 1. Active natural: Contract a disease and produce memory cells
  • 16. Acquired Immunity (pg 10) 1. Active natural: Contract a disease and produce memory cells 2. Active artificial: receive a vaccination and produce memory cells
  • 17. Acquired Immunity (pg 10) 1. Active natural: Contract a disease and produce memory cells 2. Active artificial: receive a vaccination and produce memory cells 3. Passive natural: baby receive maternal antibodies through placenta or breast milk
  • 18. Acquired Immunity (pg 10) 1. Active natural: Contract a disease and produce memory cells 2. Active artificial: receive a vaccination and produce memory cells 3. Passive natural: baby receive maternal antibodies through placenta or breast milk 4. Passive artificial: receive antiserum that contains antibodies produced in another host. Used to treat rabies, botulism, bites from venomous snakes and spiders