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“ENCOURAGE
EVERYONE TO KNOW
THEIR STATUS”
Human Immunodeficiency Virus
or HIV virus as it is commonly
known is a unique type of virus
(a retrovirus).
• A global epidemic.
• Preventable & manageable
but is NOT curable.
HIV is a lentivirus that causes the AIDS disease ,
i.e. Failure of the immune system
AIDS (Acquired
immunodeficiency
syndrome) is a
disease that can
develop in people
with HIV
Celebrated every
year on 1st of
December from 1988
To raise the public
awareness about
AIDS (Acquired
Immuno Deficiency
Syndrome).
In 2018, 30th
anniversary on 1
December, will be
“Know your
status”.
Encouraging people
to undergo medical
HIV testing
 UNAIDS estimates that
more than 9.4 million
people living with HIV
still do not know their
status.
 Stresses the importance
of knowing one’s HIV
status in the fight
against the disease
HIV testing is crucial to achieve90-90-90:
 90% of those who are HIV positive in the country know
their status,
 90% of those who know their status are on treatment
and
 90% of those who are on treatment experience
effective viral load suppression
AIDS IS:
 A: Acquired, (not inherited) to differentiate from a genetic or
inherited condition that causes immune dysfunction
 I: Immuno-, because it attacks the immune system and increases
susceptibility to infection
 D: Deficiency of certain white blood cells in the immune system
 S: Syndrome, meaning a group of symptoms or illnesses that result
from the HIV infection
 estimated at 21.40 lakhs
(15.90 lakhs–28.39 lakhs) in
2017 mostly in age group
15-49 years
 In India, the key populations
are
o Female Sex workers
o Men having sex with
Men
o Injecting Drug Users
o Trans
genders / Hijra Popul
ation

 Entry in the body through body fluids
 Virus attaches itself to immune system cells called CD4 lymphocyte cells,
 it enters the CD4 cells and start replication
 Copies kill CD4 cells after replication
 CD4 count drops so low and immune system stops working.
 Body becomes prone to infections
CAUSES OF
TRANSMISSION OF HIV
• Blood products
• Semen
• Vaginal fluids
 Sharing Needles
Without sterilization Increases the chances of contracting
HIV
 Unsterilized blades
Unprotected Intercourse:
• Oral
• Anal ( 10 times
higher rate than
vaginal sex)
• Men sex men (MSM)
• Before Birth
• During Birth
Blood-to-blood transmission
Transfusion with
HIV-infected
blood
Direct contact
with HIV-infected
blood
• Short, flu-like illness - occurs
one to six weeks after
infection
• Mild symptoms
• Infected person can infect
other people
• Lasts for an average of ten years
• This stage is free from symptoms
• There may be swollen glands
• The level of HIV in the blood drops to low levels
• HIV antibodies are detectable in the blood
• The immune system
deteriorates
• Opportunistic infections
and cancers start to
appear.
If your CD4 < 500:
• Bacterial infections
• Tuberculosis (TB)
• Herpes Simplex
• Herpes Zoster
• Vaginal candidiasis
• Hairy leukoplakia
• Kaposi’s sarcoma
If your CD4 < 200:
• Pneumocystic carinii
• Toxoplasmosis
• Cryptococcosis
• Coccidiodomycosis
• Cryptosporiosis
• Non hodgkin’s lymphoma
If your CD4 < 50:
 Disseminated mycobacterium avium complex (MAC) infection
 Histoplasmosis
 CMV retinitis
 CNS lymphoma
 Progressive multifocal leukoencephalopathy
 HIV dementia
The Most Common Opportunistic Infection:
• For HIV-infected individuals with CD4 < 200 cells/mcL:
Pneumocystis jiroveci prophylaxis
• For HIV-infected individuals with CD4 < 75 cells/mcL:
Mycobacterium avium complex prophylaxis
• For HIV-infected individuals with CD4 < 50 cells/mcL:
CMV prophylaxis
• Tuberculosis (TB) is the most common opportunistic infection in HIV
and the first cause of mortality in HIV infected patients (10-30%)
• 10 million patients co-infected in the world.
• Immunosuppression induced by HIV modifies the clinical
presentation of TB.
• No name is used.
• Unique identifying number.
• Results issued only to test recipient. 23659874515
Anonymous
HIV enzyme-linked immunosorbent
assay (ELISA)
Screening test for HIV
Sensitivity > 99.9%
Western blot Confirmatory test
Specificity > 99.9% (when combined with
ELIZA)
HIV rapid antibody test Screening test for HIV
Simple to perform
Absolute CD4 lymphocyte count Predictor of HIV progression
Risk of opportunistic infections and AIDS
when
<200
HIV viral load tests Best test for diagnosis of acute
HIV infection Correlates with
disease progression and
response to HAART
Urine Western Blot
• As sensitive as testing blood
• Safe way to screen for HIV
• Can cause false positives in certain
people at high risk for HIV
Orasure
• The only FDA approved HIV antibody.
• As accurate as blood testing
• Draws blood-derived fluids from the
gum tissue.
• NOT A SALIVATEST!
• Nucleoside Reverse Transcriptase inhibitors
AZT (Zidovudine)
• Non-Nucleoside Transcriptase inhibitors Viramune
(Nevirapine)
• Protease inhibitors Norvir
(Ritonavir)
For all HIV-infected individuals:
• CD4 counts every 3–6 months
• Viral load tests every 3–6 months and 1 month following a
change in therapy
• PPD = Tuberculosis skin test
• INH (Isoniazid) for those with positive PPD and normal chest
radiograph
• RPR (rapid plasma reagin test) or VDRL (venereal disease
research lab test) for syphilis
• Toxoplasma IgG serology
• CMV IgG serology
• Pneumococcal (pneumonia) vaccine
• Influenza vaccine in season
• Hepatitis B vaccine for those who are HBsAb-
negative
• Haemophilus influenzae type b vaccination
• Papanicolaou smears every 6 months for women.
 Conducting HIV diagnostic tests.
 Providing basic information on the modes of HIV transmission,
and promoting behavioural change to reduce vulnerability.
 Link people with other HIV prevention, care and treatment
services.
Five ways to protect yourself:
• Abstinence
• Monogamous Relationship
• Protected Sex
• Sterile needles
• New shaving/cutting blades
It is the most effective method of not acquiring HIV/AIDS.
• Refraining from unprotected sex: oral, anal, or vaginal.
• Refraining from intravenous drug use
• Use condoms every time you
have sex
• Always use latex or polyurethane
condom (not a natural skin condom)
• Always use a latex barrier during
oral sex
 Right to informed consent
 Right to confidentiality
 Right against discrimination
 Right to health
 Right to employment
• We can reduce sexual transmission of HIV.
• We can prevent mothers from dying and babies from becoming
infected with HIV.
• We can ensure that people living with HIV receive
treatment.
• We can prevent people living with HIV from dying of tuberculosis.
• We can protect drug users from becoming infected with HIV.
• We can remove punitive laws, policies, practices,
stigma and discrimination that
• Block effective responses to AIDS.
• We can stop violence against women and girls.
• We can empower young people to protect themselves from
HIV.
• We can enhance social protection for people
affected by HIV.
World aids day
World aids day

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World aids day

  • 2. Human Immunodeficiency Virus or HIV virus as it is commonly known is a unique type of virus (a retrovirus). • A global epidemic. • Preventable & manageable but is NOT curable.
  • 3. HIV is a lentivirus that causes the AIDS disease , i.e. Failure of the immune system
  • 4. AIDS (Acquired immunodeficiency syndrome) is a disease that can develop in people with HIV
  • 5. Celebrated every year on 1st of December from 1988 To raise the public awareness about AIDS (Acquired Immuno Deficiency Syndrome).
  • 6. In 2018, 30th anniversary on 1 December, will be “Know your status”. Encouraging people to undergo medical HIV testing
  • 7.  UNAIDS estimates that more than 9.4 million people living with HIV still do not know their status.  Stresses the importance of knowing one’s HIV status in the fight against the disease
  • 8. HIV testing is crucial to achieve90-90-90:  90% of those who are HIV positive in the country know their status,  90% of those who know their status are on treatment and  90% of those who are on treatment experience effective viral load suppression
  • 9. AIDS IS:  A: Acquired, (not inherited) to differentiate from a genetic or inherited condition that causes immune dysfunction  I: Immuno-, because it attacks the immune system and increases susceptibility to infection  D: Deficiency of certain white blood cells in the immune system  S: Syndrome, meaning a group of symptoms or illnesses that result from the HIV infection
  • 10.  estimated at 21.40 lakhs (15.90 lakhs–28.39 lakhs) in 2017 mostly in age group 15-49 years  In India, the key populations are o Female Sex workers o Men having sex with Men o Injecting Drug Users o Trans genders / Hijra Popul ation
  • 11.
  • 12.  Entry in the body through body fluids  Virus attaches itself to immune system cells called CD4 lymphocyte cells,  it enters the CD4 cells and start replication  Copies kill CD4 cells after replication  CD4 count drops so low and immune system stops working.  Body becomes prone to infections
  • 13.
  • 15.
  • 16. • Blood products • Semen • Vaginal fluids
  • 17.  Sharing Needles Without sterilization Increases the chances of contracting HIV  Unsterilized blades
  • 18. Unprotected Intercourse: • Oral • Anal ( 10 times higher rate than vaginal sex) • Men sex men (MSM)
  • 19. • Before Birth • During Birth
  • 21.
  • 22.
  • 23. • Short, flu-like illness - occurs one to six weeks after infection • Mild symptoms • Infected person can infect other people
  • 24. • Lasts for an average of ten years • This stage is free from symptoms • There may be swollen glands • The level of HIV in the blood drops to low levels • HIV antibodies are detectable in the blood
  • 25. • The immune system deteriorates • Opportunistic infections and cancers start to appear.
  • 26.
  • 27. If your CD4 < 500: • Bacterial infections • Tuberculosis (TB) • Herpes Simplex • Herpes Zoster • Vaginal candidiasis • Hairy leukoplakia • Kaposi’s sarcoma
  • 28. If your CD4 < 200: • Pneumocystic carinii • Toxoplasmosis • Cryptococcosis • Coccidiodomycosis • Cryptosporiosis • Non hodgkin’s lymphoma
  • 29. If your CD4 < 50:  Disseminated mycobacterium avium complex (MAC) infection  Histoplasmosis  CMV retinitis  CNS lymphoma  Progressive multifocal leukoencephalopathy  HIV dementia
  • 30. The Most Common Opportunistic Infection: • For HIV-infected individuals with CD4 < 200 cells/mcL: Pneumocystis jiroveci prophylaxis • For HIV-infected individuals with CD4 < 75 cells/mcL: Mycobacterium avium complex prophylaxis • For HIV-infected individuals with CD4 < 50 cells/mcL: CMV prophylaxis
  • 31. • Tuberculosis (TB) is the most common opportunistic infection in HIV and the first cause of mortality in HIV infected patients (10-30%) • 10 million patients co-infected in the world. • Immunosuppression induced by HIV modifies the clinical presentation of TB.
  • 32.
  • 33. • No name is used. • Unique identifying number. • Results issued only to test recipient. 23659874515 Anonymous
  • 34. HIV enzyme-linked immunosorbent assay (ELISA) Screening test for HIV Sensitivity > 99.9% Western blot Confirmatory test Specificity > 99.9% (when combined with ELIZA) HIV rapid antibody test Screening test for HIV Simple to perform Absolute CD4 lymphocyte count Predictor of HIV progression Risk of opportunistic infections and AIDS when <200 HIV viral load tests Best test for diagnosis of acute HIV infection Correlates with disease progression and response to HAART
  • 35. Urine Western Blot • As sensitive as testing blood • Safe way to screen for HIV • Can cause false positives in certain people at high risk for HIV
  • 36. Orasure • The only FDA approved HIV antibody. • As accurate as blood testing • Draws blood-derived fluids from the gum tissue. • NOT A SALIVATEST!
  • 37.
  • 38.
  • 39. • Nucleoside Reverse Transcriptase inhibitors AZT (Zidovudine) • Non-Nucleoside Transcriptase inhibitors Viramune (Nevirapine) • Protease inhibitors Norvir (Ritonavir)
  • 40. For all HIV-infected individuals: • CD4 counts every 3–6 months • Viral load tests every 3–6 months and 1 month following a change in therapy • PPD = Tuberculosis skin test • INH (Isoniazid) for those with positive PPD and normal chest radiograph • RPR (rapid plasma reagin test) or VDRL (venereal disease research lab test) for syphilis
  • 41. • Toxoplasma IgG serology • CMV IgG serology • Pneumococcal (pneumonia) vaccine • Influenza vaccine in season • Hepatitis B vaccine for those who are HBsAb- negative • Haemophilus influenzae type b vaccination • Papanicolaou smears every 6 months for women.
  • 42.  Conducting HIV diagnostic tests.  Providing basic information on the modes of HIV transmission, and promoting behavioural change to reduce vulnerability.  Link people with other HIV prevention, care and treatment services.
  • 43. Five ways to protect yourself: • Abstinence • Monogamous Relationship • Protected Sex • Sterile needles • New shaving/cutting blades
  • 44. It is the most effective method of not acquiring HIV/AIDS. • Refraining from unprotected sex: oral, anal, or vaginal. • Refraining from intravenous drug use
  • 45.
  • 46. • Use condoms every time you have sex • Always use latex or polyurethane condom (not a natural skin condom) • Always use a latex barrier during oral sex
  • 47.  Right to informed consent  Right to confidentiality  Right against discrimination  Right to health  Right to employment
  • 48. • We can reduce sexual transmission of HIV. • We can prevent mothers from dying and babies from becoming infected with HIV. • We can ensure that people living with HIV receive treatment. • We can prevent people living with HIV from dying of tuberculosis. • We can protect drug users from becoming infected with HIV.
  • 49. • We can remove punitive laws, policies, practices, stigma and discrimination that • Block effective responses to AIDS. • We can stop violence against women and girls. • We can empower young people to protect themselves from HIV. • We can enhance social protection for people affected by HIV.